Location: Biological Control of Insects Research
Project Number: 3622-22000-031-00
Start Date: Oct 01, 2005
End Date: Mar 25, 2010
1) Identify immune response factors responsible for resistance to entomopathogenic viruses, bacteria and parasitoids using proteomic, mass spectrometric, liquid chromatographic, and genomic methods; 2) Isolate and clone selected immune response factors for detailed characterization; 3) Determine the mechanisms by which these immune response factors determine virulence and host range; 4) Test the effects of foliar immunosuppressive and immunostimulatory factors upon the activities or levels of immune response factors; and 5) Determine and characterize the role of eicosanoids in the biochemical regulatory pathways coordinating immune response factors using in vitro and in vivo approaches.