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Research Project:
PHYTOCHEMICALS AND CANCER PREVENTIVE PATHWAYS: EFFECTS OF GENETIC AND EPIGENETIC FACTORS
Location: Diet, Genomics and Immunology Lab
Publications
(Clicking on the reprint icon
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Dietary phenethyl isothiocyanate inhibition of androgen-responsive LNCaP prostate cancer cell tumor growth correlates with decreased angiogenesis
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| Hudson, T., Perkins, S., Hursting, S., Young, H., Kim, Y., Wang, T., Wang, T.T. 2011. Dietary phenethyl isothiocyanate inhibition of androgen-responsive LNCaP prostate cancer cell tumor growth correlates with decreased angiogenesis. International Journal of Oncology. 40:1113-1121. |
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Chemical composition of five commercial gynostemma pentaphyllum samples and their radical scavenging, antiproliferative, and anti-inflammatory properties
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| Xie, Z., Liu, W., Huang, H., Slavin, M., Zhao, Y., Whent, M., Blackford, J., Lutterodt, H., Zhou, H., Chen, P., Wang, T.T., Liangli, Y. 2010. Chemical composition of five commercial gynostemma pentaphyllum samples and their radical scavenging, antiproliferative, and anti-inflammatory properties. Journal of Agricultural and Food Chemistry. 58(21):11243-11249. |
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Effect of resveratrol and zinc on intracellular zinc status in normal human prostate epithelial cells
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| Zhang, J., Wu, M., Schoene, N.W., Cheng, W., Wang, T.T., Alshatwi, A.A., Alsaif, M., Lei, K.Y. 2009. Effect of resveratrol and zinc on intracellular zinc status in normal human prostate epithelial cells. American Journal of Physiology - Cell Physiology. 297(3):C632-644. |
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Differential effects of resveratrol and its methylether analogs on cell cycle and apoptosis in human androgen-responsive LNCaP cancer cells
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| Wang, T.T., Schoene, N.W., Kim, Y.S., Mizuno, C.S., Rimando, A.M. 2010. Differential effects of resveratrol and its methylether analogs on cell cycle and apoptosis in human androgen-responsive LNCaP cancer cells. Molecular Nutrition and Food Research. 54(3):335-344. |
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Ligand, receptor, and cell type-dependent regulation of ABCA1 and ABCG1 mRNA in prostate cancer epithelial cells
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| Trasino, S.E., Kim, Y.S., Wang, T.T. 2009. Ligand, receptor, and cell type-dependent regulation of ABCA1 and ABCG1 mRNA in prostate cancer epithelial cells. Molecular Cancer Therapeutics. 8(7):1934-1945. |
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Molecular effects of soy phytoalexin glyceollins in human prostate cancer cells LNCaP
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| Payton-Stewart, F., Schoene, N.W., Kim, Y.S., Burrow, M.E., Cleveland, T.E., Boue, S.M., Wang, T.T. 2009. Molecular effects of soy phytoalexin glyceollins in human prostate cancer cells LNCaP. Molecular Carcinogenesis. 48(9):862-871. |
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Differential effects of resveratrol on androgen-responsive LNCaP human prostrate cancer cells in vitro and in vivo.
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| Wang, T.T., Hudson, T.S., Wang, T.C., Remsberg, C.M., Davies, N.M., Takahashi, Y., Kim, Y.S., Seifried, H., Vinyard, B.T., Perkins, S.N., Hursting, S.D. 2008. Differential effects of resveratrol on androgen-responsive LNCaP human prostrate cancer cells in vitro and in vivo. Carcinogenesis. 29(10):2001-2010. |
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Concentration-dependent effects of genistein on global gene expression in MCF-7 breast cancer cells: an oligo microarray study.
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| Lavigne, J.A., Takahashi, Y., Chandramouli, G.V., Liu, H., Shih, J., Perkins, S.N., Hursting, S.D., Barrett, J., Wang, T.T. 2007. Concentration-dependent effects of genistein on global gene expression in MCF-7 breast cancer cells: an oligo microarray study. Breast Cancer Research and Treatment. [DOI 10.1007/s10549-007-9705-6]. |
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Inhibition of prostate cancer growth by muscadine grapeskin extract and resveratrol through distinct mechanisms
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| Hudson, T.S., Hartle, D.K., Hursting, S.D., Nunez, N.P., Wang, T.T., Young, H.A., Arany, P., Green, J.E. 2007. Inhibition of prostate cancer growth by muscadine grapeskin extract and resveratrol through distinct mechanisms. Cancer Research. 67(17):8396-8405. |
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Androgen regulation of aldehyde dehydrogenase 1A3 (ALDH1A3) in androgen responsive human prostate cancer cell LNCaP.
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| Trasino, S.E., Harrison, E.H., Wang, T.T. 2007. Androgen regulation of aldehyde dehydrogenase 1A3 (ALDH1A3) in androgen responsive human prostate cancer cell LNCaP. Experimental Biology and Medicine (Maywood). 232(6):762-771. |
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MOLECULAR SIGNATURES OF SOY-DERIVED PHYTOCHEMICALS IN ANDROGEN-RESPONSIVE PROSTATE CANCER CELLS: A COMPARISON STUDY USING DNA MICROARRAY
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| Takahashi, Y., Lavigne, J.A., Hursting, S.D., Chandramouli, G.V., Perkins, S.N., Kim, Y.S., Wang, T.T. 2006. Molecular signatures of soy-derived phytochemicals in androgen-responsive prostate cancer cells: a comparison study using dna microarray. Molecular Carcinogenesis. 12:943-956. |
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ENHANCED ESTROGENIC RESPONSES AND SENSITIVITY TO AZOSYMETHANE FOLLOWING DIETARY SOY ISOFLAVONE SUPPLEMENTATION IN OLDER FEMALE RATS
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| Daly, K.T., Tracy, A.C., Malik, M., Wang, T.T., Francke-Carroll, S., Magnuson, B.A. 2007. Enhanced estrogenic responses and sensitivity to azosymethane following dietary soy isoflavone supplementation in older female rats. Food and Chemical Toxicology. 45(4):628-637. |
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DECIPHERING MOLECULAR SIGNATURES OF PHYTOCHEMICALS IN CELLS
- (Proceedings)
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| Wang, T.T., Kim, Y.S., Hursting, S.D., Perkins, S.N., Gadisetti, C.R., Lavigne, J.A., Takahashi, Y. 2005. Deciphering molecular signatures of phytochemicals in cells. UJNR Food & Agricultural Panel Proceedings. |
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