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Research Project: PHYTOCHEMICALS AND CANCER PREVENTIVE PATHWAYS: EFFECTS OF GENETIC AND EPIGENETIC FACTORS

Location: Diet, Genomics and Immunology Lab

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)

Dietary phenethyl isothiocyanate inhibition of androgen-responsive LNCaP prostate cancer cell tumor growth correlates with decreased angiogenesis - (Peer Reviewed Journal)
Hudson, T., Perkins, S., Hursting, S., Young, H., Kim, Y., Wang, T., Wang, T.T. 2011. Dietary phenethyl isothiocyanate inhibition of androgen-responsive LNCaP prostate cancer cell tumor growth correlates with decreased angiogenesis. International Journal of Oncology. 40:1113-1121.
Chemical composition of five commercial gynostemma pentaphyllum samples and their radical scavenging, antiproliferative, and anti-inflammatory properties - (Peer Reviewed Journal)
Xie, Z., Liu, W., Huang, H., Slavin, M., Zhao, Y., Whent, M., Blackford, J., Lutterodt, H., Zhou, H., Chen, P., Wang, T.T., Liangli, Y. 2010. Chemical composition of five commercial gynostemma pentaphyllum samples and their radical scavenging, antiproliferative, and anti-inflammatory properties. Journal of Agricultural and Food Chemistry. 58(21):11243-11249.
Effect of resveratrol and zinc on intracellular zinc status in normal human prostate epithelial cells - (Peer Reviewed Journal)
Zhang, J., Wu, M., Schoene, N.W., Cheng, W., Wang, T.T., Alshatwi, A.A., Alsaif, M., Lei, K.Y. 2009. Effect of resveratrol and zinc on intracellular zinc status in normal human prostate epithelial cells. American Journal of Physiology - Cell Physiology. 297(3):C632-644.
Differential effects of resveratrol and its methylether analogs on cell cycle and apoptosis in human androgen-responsive LNCaP cancer cells - (Peer Reviewed Journal)
Wang, T.T., Schoene, N.W., Kim, Y.S., Mizuno, C.S., Rimando, A.M. 2010. Differential effects of resveratrol and its methylether analogs on cell cycle and apoptosis in human androgen-responsive LNCaP cancer cells. Molecular Nutrition and Food Research. 54(3):335-344.
Ligand, receptor, and cell type-dependent regulation of ABCA1 and ABCG1 mRNA in prostate cancer epithelial cells - (Peer Reviewed Journal)
Trasino, S.E., Kim, Y.S., Wang, T.T. 2009. Ligand, receptor, and cell type-dependent regulation of ABCA1 and ABCG1 mRNA in prostate cancer epithelial cells. Molecular Cancer Therapeutics. 8(7):1934-1945.
Molecular effects of soy phytoalexin glyceollins in human prostate cancer cells LNCaP     Reprint Icon - (Peer Reviewed Journal)
Payton-Stewart, F., Schoene, N.W., Kim, Y.S., Burrow, M.E., Cleveland, T.E., Boue, S.M., Wang, T.T. 2009. Molecular effects of soy phytoalexin glyceollins in human prostate cancer cells LNCaP. Molecular Carcinogenesis. 48(9):862-871.
Differential effects of resveratrol on androgen-responsive LNCaP human prostrate cancer cells in vitro and in vivo. - (Peer Reviewed Journal)
Wang, T.T., Hudson, T.S., Wang, T.C., Remsberg, C.M., Davies, N.M., Takahashi, Y., Kim, Y.S., Seifried, H., Vinyard, B.T., Perkins, S.N., Hursting, S.D. 2008. Differential effects of resveratrol on androgen-responsive LNCaP human prostrate cancer cells in vitro and in vivo. Carcinogenesis. 29(10):2001-2010.
Concentration-dependent effects of genistein on global gene expression in MCF-7 breast cancer cells: an oligo microarray study. - (Peer Reviewed Journal)
Lavigne, J.A., Takahashi, Y., Chandramouli, G.V., Liu, H., Shih, J., Perkins, S.N., Hursting, S.D., Barrett, J., Wang, T.T. 2007. Concentration-dependent effects of genistein on global gene expression in MCF-7 breast cancer cells: an oligo microarray study. Breast Cancer Research and Treatment. [DOI 10.1007/s10549-007-9705-6].
Inhibition of prostate cancer growth by muscadine grapeskin extract and resveratrol through distinct mechanisms - (Peer Reviewed Journal)
Hudson, T.S., Hartle, D.K., Hursting, S.D., Nunez, N.P., Wang, T.T., Young, H.A., Arany, P., Green, J.E. 2007. Inhibition of prostate cancer growth by muscadine grapeskin extract and resveratrol through distinct mechanisms. Cancer Research. 67(17):8396-8405.
Androgen regulation of aldehyde dehydrogenase 1A3 (ALDH1A3) in androgen responsive human prostate cancer cell LNCaP. - (Peer Reviewed Journal)
Trasino, S.E., Harrison, E.H., Wang, T.T. 2007. Androgen regulation of aldehyde dehydrogenase 1A3 (ALDH1A3) in androgen responsive human prostate cancer cell LNCaP. Experimental Biology and Medicine (Maywood). 232(6):762-771.
MOLECULAR SIGNATURES OF SOY-DERIVED PHYTOCHEMICALS IN ANDROGEN-RESPONSIVE PROSTATE CANCER CELLS: A COMPARISON STUDY USING DNA MICROARRAY - (Peer Reviewed Journal)
Takahashi, Y., Lavigne, J.A., Hursting, S.D., Chandramouli, G.V., Perkins, S.N., Kim, Y.S., Wang, T.T. 2006. Molecular signatures of soy-derived phytochemicals in androgen-responsive prostate cancer cells: a comparison study using dna microarray. Molecular Carcinogenesis. 12:943-956.
ENHANCED ESTROGENIC RESPONSES AND SENSITIVITY TO AZOSYMETHANE FOLLOWING DIETARY SOY ISOFLAVONE SUPPLEMENTATION IN OLDER FEMALE RATS - (Peer Reviewed Journal)
Daly, K.T., Tracy, A.C., Malik, M., Wang, T.T., Francke-Carroll, S., Magnuson, B.A. 2007. Enhanced estrogenic responses and sensitivity to azosymethane following dietary soy isoflavone supplementation in older female rats. Food and Chemical Toxicology. 45(4):628-637.
DECIPHERING MOLECULAR SIGNATURES OF PHYTOCHEMICALS IN CELLS - (Proceedings)
Wang, T.T., Kim, Y.S., Hursting, S.D., Perkins, S.N., Gadisetti, C.R., Lavigne, J.A., Takahashi, Y. 2005. Deciphering molecular signatures of phytochemicals in cells. UJNR Food & Agricultural Panel Proceedings.

   

 
Project Team
Wang, Thomas - Tom
 
Project Annual Reports
  FY 2009
  FY 2008
  FY 2007
  FY 2006
  FY 2005
 
Publications
   Publications
 
Related National Programs
  Human Nutrition (107)
 
 
Last Modified: 05/22/2013
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