Publications (Clicking on the reprint icon will take you to the publication reprint.)

Comparative susceptibility of Atlantic salmon and rainbow trout to Yersinia ruckeri: relationship to O antigen serotype and resistance to serum killing - (Peer Reviewed Journal)

Haig, S., Davies, R.L., Welch, T.J., Reese, A.R., Verner-Jefferies, D. 2010. Comparative susceptibility of Atlantic salmon and rainbow trout to Yersinia ruckeri: relationship to O antigen serotype and resistance to serum killing. Veterinary Microbiology. doi:10.1016/j.vetmic.2010.06.022

Temporal and pathogen-load dependent changes in rainbow trout (Oncorhynchus mykiss) immune response traits following challenge with biotype 2 Yersinia ruckeri - (Peer Reviewed Journal)

Wiens, G.D., Vallejo, R.L. 2010. Temporal and pathogen-load dependent changes in rainbow trout (Oncorhynchus mykiss) immune response traits following challenge with biotype 2 Yersinia ruckeri. Fish and Shellfish Immunology. doi:10.1016/j.fsi.2010.06.010 29:639-647.

Bacterial kidney disease (Renibacterium salmoninarum) - (Book / Chapter)

Wiens, G.D. 2011. Bacterial kidney disease (Renibacterium salmoninarum). Fish Diseases and Disorders. 3:338-374.

Inheritance of rainbow trout Oncorhynchus mykiss spleen size and correlation with bacterial cold water disease resistance - (Abstract Only)

Wiens, G.D., Vallejo, R.L., Leeds, T.D., Palti, Y., Evenhuis, J., Welch, T.J., Rexroad Iii, C.E. 2010. Inheritance of rainbow trout Oncorhynchus mykiss spleen size and correlation with bacterial cold water disease resistance. World Aquaculture Society Meeting 2010. Paper No. 87.

High prevalence of multidrug-tolerant bacteria and associated antimicrobial resistance genes isolated from ornamental fish and their carriage water - (Peer Reviewed Journal)

Verner-Jefferies, D., Welch, T.J., Schwarz, T., Pond, M.J., Woodward, M.J., Haig, S.J., Rimmer, G.S., Roberts, E., Morrison, V., Baker-Austin, C. 2009. High prevalence of multidrug-tolerant bacteria and associated antimicrobial resistance genes isolated from ornamental fish and their carriage water. PLoS One. 4(12):1-9.

Resistance of rainbow trout to Flavobacterium psychrophilum infection: integrating selective breeding and microbial genomics - (Proceedings)

Wiens, G.D., Leeds, T.D., Vallejo, R.L., Palti, Y., Welch, T.J., Rexroad III, C.E. 2009. Resistance of rainbow trout to Flavobacterium psychrophilum infection: integrating selective breeding and microbial genomics. Flavobacterium Meeting.

Identification of flagellar motility genes in Yersinia ruckeri by transposon mutagenesis - (Peer Reviewed Journal)

Evenhuis, J., Lapatra, S.E., Verner-Jefferys, D.W., Dalsgaard, I., Welch, T.J. 2009. Identification of flagellar motility genes in Yersinia ruckeri by transposon mutagenesis. Applied and Environmental Microbiology. 75(20):6630-6633.

Resistance of rainbow trout to Flavobacterium psychrophilum infection: integrating selective breeding and microbial genomics - (Abstract Only)

Wiens, G.D., Leeds, T.D., Vallejo, R.L., Palti, Y., Welch, T.J., Rexroad Iii, C.E. 2009. Resistance of rainbow trout to Flavobacterium psychrophilum infection: integrating selective breeding and microbial genomics. Flavobacterium 2009 Meeting. Paper No. 100.

Variable regions in Flavobacterium psychrophilum strains identified by comparative genomics: application to selective breeding for cold water disease resistance - (Abstract Only)

Wiens, G.D., Lapatra, S.E., Palti, Y., Vallejo, R.L., Leeds, T.D., Welch, T.J., Rexroad III, C.E. 2009. Variable regions in Flavobacterium psychrophilum strains identified by comparative genomics: application to selective breeding for cold water disease resistance. American Fishery Society (Fish Health Section) Proceedings.

Comparative genomics of the IncA/C multidrug resistance plasmid family - (Peer Reviewed Journal)

Fricle, F., Welch, T.J., Mcdermott, P., Mammel, M., Leclerc, E., White, D., Cebula, T., Ravel, J. 2009. Comparative genomics of the IncA/C multidrug resistance plasmid family. Journal of Bacteriology. 191(15):4750-4757.

Comparative genomics of the Flavobacterium psychrophilum Frp locus - (Abstract Only)

Wiens, G.D., Lapatra, S.E., Call, D.R., Welch, T.J. 2009. Comparative genomics of the Flavobacterium psychrophilum Frp locus. American Society for Microbiology Meeting.

Identification and characterization of flagellar biosynthetic genes in Yersinia ruckeri - (Abstract Only)

Evenhuis, J., Lapatra, S., Welch, T.J. 2009. Identification and characterization of flagellar biosynthetic genes in Yersinia ruckeri. Annual Eastern Fish Health Workshop.

Microbial Genomics of Aquaculture Pathogens - (Book / Chapter)

Wiens, G.D. 2009. Microbial Genomics of Aquaculture Pathogens. In: Overturf, K., editor. Current Status of Molecular Techniques in Aquaculture. Hobolen, NJ: Wiley, John & Sons, Inc. p. 315-335.

Characterisation of geographically and temporally diverse Yersinia ruckeri isolates: evidence that UK and mainland European biotype 2 isolates represent different clonal groups - (Peer Reviewed Journal)

Wheeler, R.W., Davies, R.L., Dalsgaard, I., Garcia, J., Welch, T.J., Waqley, S., Bateman, K.S., Verner-Jeffreys, D.W. 2009. Characterization of geographically and temporally diverse Yersinia ruckeri isolates: evidence that UK and mainland European biotype 2 isolates represent different clonal groups. Diseases of Aquatic Organisms. 84:25-33.

IncA/C Plasmid-Mediated Florfenicol Resistance in the Catfish Pathogen Edwardsiella ictaluri - (Peer Reviewed Journal)

Welch, T.J., Evenhuis, J., White, D.G., Mcdermott, P.F., Harbottle, H., Miller, R., Griffin, M., Wise, D. 2008. IncA/C Plasmid-Mediated Florfenicol Resistance in the Catfish Pathogen Edwardsiella ictaluri. Antimicrobial Agents and Chemotherapy. 53(2):845-846.

Renibacterium salmoninarum p57 antigenic variation is restricted in geographic distribution and correlated with genomic markers - (Peer Reviewed Journal)

Wiens, G.D., Dale, O. 2009. Renibacterium salmoninarum p57 antigenic variation is restricted in geographic distribution and correlated with genomic markers. Diseases of Aquatic Organisms. 83:123-131.

Genome sequence of the fish pathogen Renibacterium salmoninarum suggests reductive evolution away from an environmental Arthrobacter ancestor. - (Peer Reviewed Journal)

Wiens, G.D., Rockey, D.D., Wu, Z., Crane, S., Chen, D.S., Capri, G.R., Burnett, J.R., Ponnerassary, S., Schimpma, M.J., Burd, H., Bhattacharyya, A., Rhodes, L.D., Strom, M.S. 2008. The genome sequence of Renibacterium salmoninarum suggests reductive evolution away from an environmental Arthrobacter ancestor. Journal of Bacteriology. 190(21):6970-6982.

Characterization of a bacteriophage LPS depolymerase: potential role in disease control - (Abstract Only)

Welch, T.J. 2008. Characterization of a bacteriophage LPS depolymerase: potential role in disease control. Meeting Abstract. Edinburgh International Phage Conference. Paper No. 105.

Characterization of anti-channel catfish MHC class II monoclonal antibodies - (Peer Reviewed Journal)

Moulana, M., Evenhuis, J., Kountikov, E.I., Wilson, M., Bengten, E., Miller, N.W., Mcconnell, T. 2008. Characterization of anti-channel catfish MHC class II monoclonal antibodies. Veterinary Immunology and Immunopathology. 126:120-130.

Integrating selective breeding with microbial genomics to improve rainbow trout disease resistance - (Abstract Only)

Wiens, G.D. 2008. Integrating selective breeding with microbial genomics to improve rainbow trout disease resistance. Meeting Abstract. p. 104.

Challenges associated with heterologous expression of Flavobacterium psychrophilum proteins in Escherichia coli - (Peer Reviewed Journal)

Shah, D.H., Cain, K.D., Wiens, G.D., Call, D.R. 2008. Challenges associated with heterologous expression of Flavobacterium psychrophilum proteins in Escherichia coli. Marine Biotechnology. 10(6):719-730. Epub 2008 Jun 13.

Spleen Size Predicts Resistance of Rainbow Trout to Flavobacterium psychrophilum Challenge - (Peer Reviewed Journal)

Hadidi, S., Glenney, G., Welch, T.J., Silverstein, J., Wiens, G.D. 2008. Spleen Size Predicts Resistance of Rainbow Trout to Flavobacterium psychrophilum Challenge. Journal of Immunology. 180:4156-4165.

Cortisol Response to a Crowding Stress: Heritability and Association with Disease Resistance to Yersinia ruckeri in Rainbow Trout - (Peer Reviewed Journal)

Weber, G.M., Vallejo, R.L., Lankford, S.E., Silverstein, J., Welch, T.J. 2008. Cortisol Response to a Crowding Stress: Heritability and Association with Disease Resistance to Yersinia ruckeri in Rainbow Trout. North American Journal of Aquaculture.

Recent Advances in Bacterial Coldwater Disease Research - (Trade Journal)

Wiens, G.D., Welch, T.J. 2007. Recent Advances in Bacterial Coldwater Disease Research. Trout Talk Pg 5-6.

Rainbow Trout Innate Immunity against Flavobacterium psychrophilum - (Abstract Only)

Hadidi, S., Glenney, G.W., Welch, T.J., Silverstein, J., Blazer, V., Wiens, G.D. 2007. Rainbow Trout Innate Immunity against Flavobacterium psychrophilum. Meeting Abstract Pg 35.

Genome Sequence of Flavobacterium psychrophilum Strain CSF 259-93 and Characterization of a Large Cluster of Genes Containing Short Repeats - (Abstract Only)

Wiens, G.D., Welch, T.J., Rexroad III, C.E., Lapatra, S., Call, D.R., Hunnicutt, D., Bhattacharyya, A., Campbell, J., Walunas, T. 2007. Genome Sequence of Flavobacterium psychrophilum Strain CSF 259-93 and Characterization of a Large Cluster of Genes Containing Short Repeats. Meeting Abstract Pg 12.

Early Diversification of the Tumor Necrosis Superfamily in Teleosts: Genomic Characterization and Expression Analysis - (Peer Reviewed Journal)

Glenney, G.W., Wiens, G.D. 2007. Early Diversification of the Tumor Necrosis Superfamily in Teleosts: Genomic Characterization and Expression Analysis. Journal of Immunology, 178:7955-7973.

Transcription termination Within the iron transport-biosynthesis operon of Vibrio anguillarum requires an antisense RNA - (Peer Reviewed Journal)

Stork, M., Di Lorenzo, M., Welch, T.J., Crosa, J. 2007. Transcription termination Within the iron transport-biosynthesis operon of Vibrio anguillarum requires an antisense RNA. Journal of Bacteriology 189:(9), 3479-88.

Multiple Antimicrobial Resistance in Plague: An Emerging Public Health Risk - (Peer Reviewed Journal)

Welch, T.J., Fricke, W.F., Rosso, M.L., Rasko, D.A., Mammel, M., Eppinger, M., Rosovitz, M.J., White, D.G., Mcdermott, P.F., Wagner, D., Rahalison, L., Leclerc, J.E., Hinshaw, J.M., Lindler, L.E., Cebula, T.A., Carniel, E., Ravel, J. 2007. Multiple Antimicrobial Resistance in Plague: An Emerging Public Health Risk. PLoS One. Vol.1 (3)1-6.

Distribution of Yersinia pestis pIP1202-like Multidrug Resistance Plasmids Among Foodborne Pathogens - (Abstract Only)

Welch, T.J., Fricke, W.F., Eppinger, M., Rosovitz, M.J., Mcdermott, P., White, D., Wiens, G.D., Ravel, J. 2007. Distribution of Yersinia pestis pIP1202-like Multidrug Resistance Plasmids Among Foodborne Pathogens. American Society of Microbiologists Abstracts.

Spleen Size Predicts Innate Resistance of Rainbow Trout to Flavobacterium psychrophilum Challenge - (Abstract Only)

Hadidi, S., Glenney, G., Welch, T.J., Silverstein, J., Wiens, G.D. 2007. Spleen Size Predicts Innate Resistance of Rainbow Trout to Flavobacterium psychrophilum Challenge. American Society for Microbiology.

Identification of potential vaccine target antigens by immunoproteomic analysis of a virulent and a non-virulent strain of the fish pathogen Flavobacterium psychrophilum - (Peer Reviewed Journal)

Sudheesh, P.S., Lafrentz, B.R., Call, D.R., Siems, W.F., Lapatra, S.E., Wiens, G.D., Cain, K.D. 2007. Identification of potential vaccine target antigens by immunoproteomic analysis of a virulent and a non-virulent strain of the fish pathogen Flavobacterium psychrophilum. Diseases of Aquatic Organisms. 74(1):37-47.

GENOMIC AND FUNCTIONAL-GENETIC CHARACTERIZATION OF BACTERIOPHAGE NC10 REVEALS A NOVEL Yersinia ruckeri VIRULENCE NEUTRALIZING ACTIVITY - (Abstract Only)

Welch, T.J. 2006. Genomic and functional-genetic characterization of bacteriophage nc10 reveals a novel yersinia ruckeri virulence neutralizing activity. Meeting Abstract pg 272.

Application of Microbial Genomics to Improve Aquatic Animal Health - (Abstract Only)

Wiens, G.D. 2006. Application of Microbial Genomics to Improve Aquatic Animal Health. Meeting Abstract.

GENOTYPE DIET INTERACTIONS IN RAINBOW TROUT FAMILIES FED DIETS WITH AND WITHOUT HIGH LEVELS OF SOYBEAN MEAL INCLUSION - (Abstract Only)

Silverstein, J., Hardy, R., Casten, M., Barrows, F. 2006. Genotype diet interactions in rainbow trout families fed diets with and without high levels of soybean meal inclusion. International Symposium on Genetics in Aquaculture. p. 97.

GENE EXPRESSION AND CELLULAR IMMUNE RESPONSE OF RAINBOW TROUT (ONCORHYNCHUS MYKISS) EXPOSED TO YERSINIA RUCKERI: A MODEL SYSTEM FOR UNDERSTANDING MECHANISMS OF TELEOST PROTECTIVE IMMUNITY - (Abstract Only)

Wiens, G.D., Lapatra, S., Palti, Y., Rexroad III, C.E., Yao, J., Welch, T.J. 2006. Gene expression and cellular immune response of rainbow trout (Oncorhynchus mykiss) exposed to Yersinia ruckeri: A model system for understanding mechanisms of teleost protective immunity. 10th International Congress, International Society of Developmental and Comparative Immunology, July 1 - 6, 2006. Meeting Abstract. Page 249.

EARLY DIVERSIFICATION OF THE TUMOR NECROSIS SUPERFAMILY IN TELEOSTS: GENOMIC CHARACTERIZATION AND EXPRESSION ANALYSIS - (Abstract Only)

Glenney, G., Wiens, G.D. 2006. Early diversification of the tumor necrosis superfamily in teleosts: genomic characterization and expression analysis. 10th International Congress, International Society of Developmental and Comparative Immunology. Meeting Abstract Page 113.

BACTERIAL KIDNEY DISEASE - (Book / Chapter)

Wiens, G.D. 2006. Bacterial kidney disease. Aquaculture Compendium. Online at www.cabicompendium.org/ac. Wallingford, UK: CAB International

PERFORMANCE OF A ROTATING BIOLOGICAL CONTRACTOR IN TILAPIA RECIRCULATING AQUACULTURE SYSTEM - (Popular Publication)

Brazil, B.L. 2006. Performance of a rotating biological contractor in tilapia recirculating aquaculture system. Aquaculture Magazine, 32(3) 52-59.

IDENTIFICATION OF NOVEL RAINBOW TROUT (ONCHORYNCHUS MYKISS) CHEMOKINES, CXCD1 AND CXCD2: MRNA EXPRESSION FOLLOWING YERSINIA RUCKERI VACCINATION AND CHALLENGE - (Peer Reviewed Journal)

Wiens, G.D., Glenney, G.W., Lapatra, S.E., Welch, T.J. 2006. Identification of novel rainbow trout (Onchorynchus mykiss) chemokines, cxcd1 and cxcd2: Mrna expression following Yersinia ruckeri vaccination and challenge. Immunogenetics. 2006 May;58(4):308-23. Epub 2006 Mar 29.

ANTIGENIC VARIATION IN RENIBACTERIUM SALMONINARUM P57: FUNCTIONAL AND DIAGNOSTIC IMPLICATIONS - (Abstract Only)

Wiens, G.D., Ole Bendik, D. 2005. Antigenic variation in Renibacterium salmoninarum p57: functional and diagnostic implications. Bacterial Kidney Disease: Challenges for the 21st Century. Meeting Abstract. November 15-17, 05 Seattle, WA p. 21.

NOVEL VACCINE TARGETS AND ASSESSMENT OF CELLULAR IMMUNITY - (Abstract Only)

Wiens, G.D. 2005. Novel vaccine targets and assessment of cellular immunity.Workshop on genomics of Renibacterium saloninarum. Meeting Abstract Bacterial Kidney Disease: Challenges for the 21st Century. p. 12.

GROWTH AND PHYSIOLOGICAL CHARACTERISTICS OF RAINBOW TROUT REARED IN DIFFERENT CULTURE ENVIRONMENTS - (Abstract Only)

Brazil, B.L., Silverstein, J. 2005. Growth and physiological characteristics of rainbow trout reared in different culture environments. Meeting Abstract, Volume 12.

CHARACTERIZATION OF A BACTERIOPHAGE SPECIFIC FOR THE SALMONID PATHOGEN YERSINIA RUCKERI - (Abstract Only)

Welch, T.J. 2005. Characterizaion of a bacteriophage specific for the salmonid pathogen yersinia ruckeri. Evergreen International Phage Meeting. the Evergreen State College, Olympia, WA. p. A-43.

IDENTIFICATION AND EXPRESSION OF AN IMMUNO-REACTIVE HEAT SHOCK PROTEIN FROM FLAVOBACTERIUM PSYCHROPHILUM - (Abstract Only)

Cain, K., Sudheesh, P.S., Lapatra, S.E., Wiens, G.D., Lafrentz, B.R., Call, D.R. 2005. Identification and expression of an immuno-reactive heat shock protein from flavobacterium psychrophilum. Annual Meeting of the Fish Health Section/American Fisheries Society. (abstract).

ESTIMATION OF THE GENOME SIZE OF RENIBACTERIUM SALMONINARUM ATCC 33209 BY PULSED-FIELD GEL ELECTROPHORESIS - (Abstract Only)

Wiens, G.D., Strom, M.S. 2005. Estimation of the genome size of renibacterium salmoniarum atcc 33209 by pulsed-tield gel electrophoresis. (Abstract). 30th Eastern Fish Health Workshop. p. 8.