Location: Natural Products Utilization Research
2007 Annual Report
Life-Pharms project: To date 5,846 samples have been processed for antifungal evaluation. This year (2007) alone, we have evaluated 336 new crude extracts utilizing bioautography. We have determined 23 primary leads from the first four plates evaluated, as well as 40 compounds of secondary secondary importance, and about 40 extracts that present activity of interest which do not fit into the other two priority groups. Of all the samples evaluated we have a total of 61 primary leads, about 400 secondary leads, and about 250 extracts that appear to be of interest. We have received 18 follow up samples, several of sufficient quantity to pursue towards structure elucidation of identified actives.
Tabanca, N., Demirci, B., Can Baser, K., Mincsovics, E., Khan, S.I., Jacob, M.R., Wedge, D.E. 2007. Characterization of Volatile Constituents of Scaligeria tripartita and Studies on the Antifungal Activity Against Phytopathogenic Fungi. Journal of Chromatography B. V. 850:221-229.
Can Baser, K., Tabanca, N., Kirimer, N., Bedir, E., Khan, I.A., Wedge, D.E. 2007. Recent Advances in the Chemistry and Biological Activities of the Pimpinella Species of Turkey. Journal of Pure and Applied Chemistry. V. 79(4):539-556.
Tabanca, N., Pawar, R.S., Ferreira, D., Marais, J.J., Khan, S.I., Wedge, D.E., Khan, I.A. 2007. Flavan-3-ol-phenylpropanoid Conjugates from Anemopaegma arvense and Their Antioxident Activites. Planta Medica. 73:1107-1111.
Wedge, D.E., Smith, B.J., Quebedeaux, J.P., Constantin, R.J. 2007. Fungicide Management Strategies for Control of Strawberry Fruit Rot Diseases in Louisiana and Mississippi. Crop Protection Journal. 26:1449-1458.