Publications (Clicking on the reprint icon will take you to the publication reprint.)

Elimination of a disulfide bridge in Aspergillus niger NRRL 3135 Phytase (PhyA) enhances heat tolerance and optimizes its temperature versus activity profile - (Peer Reviewed Journal)

Mullaney, E., Sethumadhavan, K., Boone, S., Lei, X.G., Ullah, A.H.J. 2012. Elimination of a disulfide bridge in Aspergillus niger NRRL 3135 Phytase (PhyA) enhances heat tolerance and optimizes its temperature versus activity profile. Advances in Biological Chemistry. 2(4):372-378.

Ethanol tolerance in Aspergillus niger and Escherichia coli phytase - (Peer Reviewed Journal)

Mullaney, E.J., Sethumadhavan, K., Boone, S., Ullah, A.H.J. 2012. Ethanol tolerance in Aspergillus niger and Escherichia coli phytase. Advances in Microbiology. 2(3):395-398.

Impact of Assay conditions on activity estimate and kinetics comparison of Aspergillus niger PhyA and Escherichia coli AppA2 phytases     - (Peer Reviewed Journal)

Weaver, J.D., Ullah, A.H., Sethumadhavan, K., Mullaney, E.J., Lei, X.G. 2009. Comparisons of activity assay methods and kinetics of Aspergillus niger PhyA and Escherichia coli AppA2 phytases. Journal of Agriculture and Food Chemistry. 57:5315-5320.

Unfolding and Refolding of Aspergillus Niger PhyB Phytase: Role of Disulfide Bridges - (Peer Reviewed Journal)

Ullah, A.H., Sethumadhavan, K., Mullaney, E.J. 2008. Unfolding and Refolding of Aspergillus Niger PhyB Phytase: Role of Disulfide Bridges. Journal of Agriculture and Food Chemistry. 56(17):8179-8183.

Kinetic Characterization of O-Phospho-L-Tyrosine Phosphohydrolase Activity of Two Fungal Phytases. - (Peer Reviewed Journal)

Ullah, A.H., Sethumadhavan, K., Mullaney, E.J. 2008. Kinetic characterization of o-phospho-L-tyrosine phosphohydrolase activity of two fungal phytases. Journal of Agriculture and Food Chemistry. 56(16):7467-7471.

OPTIMIZING THE PH PROFILE OF FUNGAL PHYTASE THROUGH PROTEIN ENGINEERING ALSO ENHANCES ACTIVITY - (Abstract Only)

Mullaney, E.J., Ullah, A.H., Sethumadhavan, K., Lei2, X. 2007. Optimizing the ph profile of fungal phytase through protein engineering also enhances activity (abstract). Society of Industrial Microbiology Annual Meeting. p. 146.

Altering the Substrate Specificity Site of Aspergillus Niger PhyB shifts the pH optimum to pH 3.2 - (Peer Reviewed Journal)

Weaver, J.D., Mullaney, E.J., Lei, X.G. 2007. Altering the substrate specificity site of aspergillus niger PhyB shifts the pH optimum to pH 3.2. Applied Microbiology and Biotechnology. (2007)76:117-122.

Enzymatic Comparisons of Aspergillus niger PhyA and Escherichia coli AppA2 Phytases - (Abstract Only)

Weaver, J.D., Ullah, A.H., Sethumadhavan, K., Mullaney, E.J., Lei, X.G. 2007. Enzymatic comparisons of Aspergillus Niger PhyA and Escherichia Coli AppA2 Phytases (abstract). Journal of Animal Science. 85(Supplement 1):647.

ADOPTING SELECTED HYDROGEN BONDING AND IONIC INTERACTIONS FROM ASPERGILLUS FUMIGATUS PHYTASE STRUCTURE IMPROVES THE THERMOSTABILITY OF ASPERGILLUS NIGER PHYA PHYTASE - (Peer Reviewed Journal)

Zhang, W., Mullaney, E.J., Lei, X. 2007. Adopting selected hydrogen bonding and ionic interactions from Aspergillus fumigatus phytase structure improves the thermostability of Aspergillus niger PhyA phytase. Applied and Environmental Microbiology. 73(9):3069-3076.

SHIFTING THE PH PROFILE OF ASPERGILLUS NIGER PHYA PHYTASE TO MATCH THE STOMACH PH ENHANCES ITS EFFECTIVENESS AS AN ANIMAL FEED ADDITIVE - (Peer Reviewed Journal)

Kim, T., Mullaney, E.J., Porres, J.M., Roneker, K.R., Crowe, S., Rice, S., Ko, T., Ullah, A.H., Daly, C.B., Welch, R.M., Lei, X.G. 2006. Shifting the ph profile of Aspergillus niger PhyA phytase to match the stomach ph enhances its effectiveness as an animal feed additive. Applied and Environmental Microbiology. 72(6):4397-4403.

TRANSPORT OF CALCIUM ACROSS CACO-2 CELLS IN THE PRESENCE OF INOSITOL HEXAKISPHOSPHATE - (Peer Reviewed Journal)

Phillippy, B.Q. 2006. TRANSPORT OF CALCIUM ACROSS CACO-2 CELLS IN THE PRESENCE OF INOSITOL HEXAKISPHOSPHATE. Nutrition Research. 26(3):146-149.

PHYTASE: SOURCE, STRUCTURE, AND APPLICATION - (Book / Chapter)

Lei, X. G., Porres, J. M., Mullaney, E. J. and Brinch-Pedersen, H. 2007. Phytase: source, structure and application. In: Industrial Enzymes, structure, function and applications. Editied by Polina, J. and MacCabe, A. P. Springer, Dordrecht, The Netherlands, p. 505-529.

CONSERVATION OF AN EIGHT-CYSTEINE MOTIF IN FUNGAL HISTIDINE ACID PHOSPHATASES - (Abstract Only)

Mullaney, E.J., Ullah, A.H. 2005. Conservation of an eight-cysteine motif in fungal histidine acid phosphatases (abstract). Mycological Society of America. p. 169.

PHYTASES: ATTRIBUTES, CATALYTIC MECHANISMS AND APPLICATIONS - (Abstract Only)

Mullaney, E.J., Ullah, A.H. 2005. Phytases: attributes, catalytic mechanisms and applications (abstract). Inositol Phosphates in the Plant and Soil System. p.17-18.

MONITORING OF UNFOLDING AND REFOLDING IN FUNGAL PHYTASE (PHYA) BY DYNAMIC LIGHT SCATTERING - (Peer Reviewed Journal)

Ullah, A.H., Sethumadhavan, K., Mullaney, E.J. 2005. Monitoring of unfolding and refolding in fungal phytase (phyA) by dynamic light scattering. Biochemical and Biophysical Research Communications. 327(4):993-998.

CONSERVATION OF CYSTEINE RESIDUES IN FUNGAL HISTIDINE ACID PHYTASES - (Peer Reviewed Journal)

Mullaney, E.J., Ullah, A.H., 2005. Conservation of cysteine residues in fungal histidine acid phytases. Biochemical and Biophysical Research Communications. Biochemical and Biophysical Research Communications. 328(2):404-408.