Location: Tick and Biting Fly Research
Project Number: 6205-32000-026-00
Start Date: Jun 01, 2004
End Date: May 31, 2009
Basic information on the structure of the B. microplus genome will be obtained from information derived from a normalized cDNA library approach and the creation of a BAC library. Gene silencing through use of RNA interference will be used to reduce expression of targeted genes, and assist in the elucidation of their metabolic, biochemical, or structural roles. By focusing on the components of the tick proteome associated with events associated with tick feeding and the facilitation of pathogen transmission, proteins involved in tick feeding and life-stage related differences in protein expression will be identified and related to function.