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Research Project: IMPACT OF NUTRITIONAL STATUS ON IMMUNE-INDUCED CHANGES IN GUT FUNCTION

Location: Diet, Genomics and Immunology Lab

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)

Critical requirement for the Wiskott-Aldrich syndrome protein in Th2 effector function - (Peer Reviewed Journal)
Morales-Tirado, V., Sojka, D.K., Katzman, S.D., Lazarski, C.A., Finkelman, L.D., Urban Jr, J.F., Fowell, D.J. 2010. Critical requirement for the Wiskott-Aldrich syndrome protein in Th2 effector function. Blood. 115(17):3498-3507.
Intestinal epithelial cell secretion of RELM-beta protects against gastrointestinal worm infection - (Peer Reviewed Journal)
Herbert, D.R., Yang, J.Q., Hogan, S.P., Groschwitz, K., Khodoun, M., Munitz, A., Orekov, T., Perkins, C., Wang, Q., Brombacher, F., Urban Jr, J.F., Rothenberg, M.E., Finkelman, F.D. 2009. Intestinal epithelial cell secretion of RELM-beta protects against gastrointestinal worm infection. Journal of Experimental Medicine. 206(13):2947-2957.
IL-13 receptor alpha-2 regulates the immune and functional response to Nippostrongylus brasiliensis infection - (Peer Reviewed Journal)
Morimoto, M., Zhao, A., Sun, R., Stiltz, J., Madden, K.B., Mentink-Kane, M., Ramalingam, T., Wynn, T.A., Urban Jr, J.F., Shea-Donohue, T. 2009. IL-13 receptor alpha-2 regulates the immune and functional response to Nippostrongylus brasiliensis infection. Journal of Immunology. 183(3):1934-1999.
Quantitative evaluation of his-tag purification and immunoprecipitation of tristetraprolin and its mutant proteins from transfected human cells - (Peer Reviewed Journal)
Cao, H., Lin, R. 2009. Quantitative evaluation of his-tag purification and immunoprecipitation of tristetraprolin and its mutant proteins from transfected human cells. Biotechnology Progress. 25:461-467.
Anti-inflammatory Mechanisms of Enteric Heligmosomoides polygyrus Infection on TNBS-Induced Colitis in a Murine Model - (Peer Reviewed Journal)
Sutton, T.L., Zhao, A., Madden, K.B., Elfrey, J.E., Tuft, B.A., Sullivan, C.A., Urban Jr, J.F., Shea-Donohue, T. 2008. Anti-inflammatory mechanisms of enteric Heligmosomoides polygyrus infection on TNBS-induced colitis in a murine model. Infection and Immunity 76(10):4772-82.
Th2 cytokine-induced alterations in intestinal smooth muscle function depend on alternatively activated macrophages - (Peer Reviewed Journal)
Zhao, A., Urban Jr, J.F., Anthony, R.M., Sun, R., Stiltz, J., van Rooijen, N., Wynn, T.A., Gause, W.C., Shea-Donohue, T. 2008. Th2 cytokine-induced alterations in intestinal smooth muscle function depend on alternatively activated macrophages. Gastroenterology. 135(1):217-225.
Production and characterization of ZFP36L1 antiserum against recombinant protein from Escherichia coli - (Peer Reviewed Journal)
Cao, H., Lin, R., Ghosh, S., Anderson, R.A., Urban Jr, J.F. 2008. Production and characterization of ZFP36L1 antiserum against recombinant protein from Escherichia coli. Biotechnology Progress. 24(2)326-333.
Production and Characterization of ZFP36L1 Antiserum Against Recombinant Protein From Escherichia coli - (Abstract Only)
Cao, H., Lin, R., Ghosh, S., Anderson, R.A., Urban Jr, J.F. 2008. Production and Characterization of ZFP36L1 Antiserum Against Recombinant Protein From Escherichia coli. [abstract]. Journal of Federation of American Societies for Experimental Biology. 22:1003.7.
Heligmosomoides polygyrus promotes T regulatory cytokine production in the normal distal murine intestine. - (Peer Reviewed Journal)
Setiawan, T., Metwali, A., Blum, A., Urban Jr, J.F., Elliott, D., Weinstock, J. 2007. Heligmosomoides polygyrus promotes T regulatory cytokine production in the normal distal murine intestine. Infection and Immunity.
Amphiregulin-a Th2 cytokine enhancing resistance to nematodes - (Peer Reviewed Journal)
Zaiss, D.M., Yang, L., Shah, P.R., Kobie, J.J., Urban, J.F., Mosmann, T.R. 2006. Amphiregulin-a TH2 cytokine enhancing resistance to nematodes. Science. 314(5806):1746.
Il-4producing memory T-cells induce alternatively activated macrophages to mediate protection against nematode parasites. - (Peer Reviewed Journal)
Anthony, R.M., Urban Jr, J.F., Alem, F., Hamed, H.A., Boucher, J., Van Rooijen, N., Gauge, W.C. 2006. IL-4-producing memory T cells induce alternatively activated macrophages to mediate protection against nematode parasites. Nature (Medicine). 12(8):955-960.
IL-18 STIMULATES IL-13 MEDIATED IFN-GAMMA SENSITIVE HOST RESISTANCE IN VIVO - (Peer Reviewed Journal)
Liu, Q., Liu, Z., Whitmire, J., Alem, F., Hamed, H., Pesce, J., Urban Jr, J.F., Gause, W. 2006. IL-18 stimulates IL-13 mediated INF-gamma sensitive host resistance in vivo. European Journal of Immunology. 36(5):1187-1198.
CONTRIBUTION OF 5-HT2A RECEPTOR IN NEMATODE INFECTION-INDUCED MURINE INTESTINAL SMOOTH MUSCLE HYPER CONTRACTILITY - (Peer Reviewed Journal)
Zhao, A., Urban, Jr, J.F., Morimoto, M., Elfrey, J., Madden, K., Finkelman, F., Shea-Donohue, T. 2006. Contribution of 5-HT2A receptor in nematode infection-induced murine intestinal smooth muscle hyper contractility. Gastroenterology. 131(2):568-578
FUNCTIONAL IMPORTANCE OF REGIONAL DIFFERENCES IN LOCALIZED GENE EXPRESSION OF RECEPTORS FOR IL-13 IN MURINE GUT - (Peer Reviewed Journal)
Morimoto, M., Morimoto, M., Zhao, A., Madden, K., Dawson, H., Finkleman, F., Mentink-Kane, M., Urban Jr., J.F., Wynn, T., and Shea-Donohue, T. 2006. Functional importance of regional differences in localized gene expression of receptors for IL-13 in murine gut. Journal of Immunology. 176(1):491-495.
ALTERNATIVELY ACTIVATED MACROPHAGES ACCUMULATE AT THE HOST PARASITE INTERFACE AND CONTRIBUTE TO PROTECTION AGAINST A NEMATODE PARASITE. - (Abstract Only)
Anthony, R., Urban Jr, J.F., Alem, F., Hamed, H., Van Rooijen, N., Gause, W. 2005. Alternatively activated macrophages accumulate at the host parasite interface and contribute to protection against a nematode parasite.. Meeting Abstract.
IMMUNE REGULATION OF PROTEASE-ACTIVATED RECEPTOR-1 EXPRESSION IN MURINE SMALL INTESTINE DURING NIPPOSTRONGYLUS BRASILIENSIS INFECTION - (Peer Reviewed Journal)
Zao, A., Morimoto, M., Dawson, H., Elfrey, J.E., Madden, K.B., Gause, W.C., Min, B., Finkelman, F.D., Urban, J.F. Jr., Shea-Donohue, T. 2005. Immune regulation of protease-activated receptor-1 expression in murine small intestine during nippostrongylus brasiliensis infection. Journal of Immunology. 175(4):2563-2569.
THE IL-21 RECEPTOR AUGUMENTS TH2 EFFECTOR FUNCTION AND ALTERNATIVE MACROPHAGE ACTIVATION. - (Peer Reviewed Journal)
Pesce, J., Kaviratne, M., Ramalingam, T., Thompson, R.W., Urban Jr, J.F., Cheever, A., Young, D., Collins, M., Grusby, M., Wynn, T. 2006. The IL-21 receptor auguments Th2 effector function and alternative macrophage activation. Journal of Clinical Investigation. 116(7):2044-2055.
CONDITIONAL DELETION OF GATA-3 REVEALS ITS CRITICAL ROLE IN TH1/TH2 RESPONSES - (Peer Reviewed Journal)
Zhu, J., Min, B., Hu-Li, J., Watson, C., Grinberg, A., Wang, Q., Killeen, N., Urban Jr, J.F., Guo, L., Paul, W. 2004. Conditional deletion of gata-3 reveals its critical role in th1/th2 responses. Nature Immunology. 5(11):1157-1165.
HELIGMOSOMOIDES POLYGYRUS INHIBITS ESTABLISHED COLITIS IN IL-10 DEFICIENT MICE - (Peer Reviewed Journal)
Elliott, D.E., Setiawan T., Metwali, A., Blum, A., Urban, Jr., J.F., Weinstock, J.V. 2004. Heligmosomoides polygyrus inhibites established colitis in IL-10 deficient mice. European Journal of Immunology. 34:2690-2696.
DEPENDENCE OF I1-4, IL-13, AND NEMATODE-INDUCED ALTERATIONS IN MURINE SMALL INTESTINAL SMOOTH MUSCLE CONTRACTILITY ON STAT6 AND ENTERIC NERVES - (Peer Reviewed Journal)
Zhao, A., Mcdermott, J., Urban Jr, J.F., Gause, W., Madden, K., Auyeung, K., Morris, S., Finkelman, F., Shea-Donohue, T. 2004. Dependence of i1-4, il-13, and nematode-induced alterations in murine small intestinal smooth muscle contractility on stat6 and enteric nerves. Journal of Immunology. 171:948-954 (2003).

   

 
Project Team
Urban, Joseph
Dawson, Harry
Smith, Allen
 
Project Annual Reports
  FY 2009
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  FY 2005
 
Publications
   Publications
 
Related National Programs
  Human Nutrition (107)
 
 
Last Modified: 06/19/2013
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