Publications (Clicking on the reprint icon will take you to the publication reprint.)

Sulfur amino acid metabolism in children with severe childhood undernutrition: cysteine kinetics - (Peer Reviewed Journal)

Jahoor, F., Badaloo, A., Reid, M., Forrester, T. 2006. Sulfur amino acid metabolism in children with severe childhood undernutrition: Cysteine kinetics. American Journal of Clinical Nutrition. 84(6):1393-1399.

The bovine lactation genome: Insights into the evolution of mammalian milk - (Peer Reviewed Journal)

Lemay, D.G., Lynn, D.J., Martin, W.F., Neville, M.C., Casey, T.M., Rincon, G., Kriventseva, E.V., Barris, W.C., Hinrichs, A.S., Molenaar, A.J., Pollard, K.S., Maqbool, N.J., Singh, K., Murney, R., Zdobnov, E.M., Tellam, R.L., Medrano, J.F., German, J.B., Rijnkels, M. 2009. The bovine lactation genome: Insights into the evolution of mammalian milk. Genome Biology. 10(4):R43.1-R43.18.

Lessons from the bovine genome: Implications for human nutrition and research - (Review Article)

Lemay, D.G., Rijnkels, M., German, J.B. 2009. Lessons from the bovine genome: Implications for human nutrition and research. Journal of Nutrition. 139:1271-1271.

Undernutrition malnutrition in infants in developing countries - (Other)

Ashorn, P., Phuka, J.C., Maleta, K., Thakwalakwa, C., Cheung, Y.B., Briend, A., Manary, M.J. 2009. Undernutrition malnutrition in infants in developing countries. Archives of Pediatrics and Adolescent Medicine. 163(2):186.

Supplementary feeding with fortified spreads results in higher recovery rates than with a corn/soy blend in moderately wasted children - (Peer Reviewed Journal)

Matilsky, D.K., Maleta, K., Castleman, T., Manary, M.J. 2009. Supplementary feeding with fortified spreads results in higher recovery rates than with a corn/soy blend in moderately wasted children. Journal of Nutrition. 139(4):773-778.

Twenty-four-hour simultaneous subcutaneous basal-bolus administration of insulin and amylin in adolescents with type 1 diabetes decreases postprandial hyperglycemia - (Peer Reviewed Journal)

Heptulla, R.A., Rodriguez, L.M., Mason, K.J., Haymond, M.W. 2009. Twenty-four-hour simultaneous subcutaneous basal-bolus administration of insulin and amylin in adolescents with type 1 diabetes decreases postprandial hyperglycemia. Journal of Clinical Endocrinology and Metabolism. 94(5):1608-1611.

Supplementary feeding with either ready-to-use fortified spread or corn-soy blend in wasted adults starting antiretroviral therapy in Malawi: Randomised, Investigator Blinded, Controlled Trial - (Peer Reviewed Journal)

Ndekha, M.J., Van Oosterhout, J.J.G., Zijlstra, E.E., Manary, M., Saloojee, H., Manary, M.J. 2009. Supplementary feeding with either ready-to-use fortified spread or corn-soy blend in wasted adults starting antiretroviral therapy in Malawi: Randomised, Investigator Blinded, Controlled Trial. British Medical Journal. 338:b1867.

Gene expression in the human mammary epithelium during lactation: the milk fat globule transcriptome. - (Peer Reviewed Journal)

Maningat, P.D., Sen, P., Rijnkels, M., Sunehag, A.L., Hadsell, D.L., Bray, M., Haymond, M.W. 2009. Gene expression in the human mammary epithelium during lactation: The milk fat globule transcriptome. Physiological Genomics. 37(1):12-22.

Technical note: Assessing the functional capacity of mitochondria isolated from lactating mammary tissue: Choose your chelating agent wisely - (Peer Reviewed Journal)

Hadsell, D.L., George, J., Abraham, P.A., Collier, R.J., Lambert, B.D. 2009. Technical note: Assessing the functional capacity of mitochondria isolated from lactating mammary tissue: Choose your chelating agent wisely. Journal of Dairy Science. 92:2038-2045.

Whole-body CO2 production as an index of the metabolic response to sepsis - (Peer Reviewed Journal)

Kao, C.C., Guntupalli, K.K., Bandi, V., Jahoor, F. 2009. Whole-body CO2 production as an index of the metabolic response to sepsis. SHOCK. 32(1):23-28.

Management of acute moderate and severe childhood malnutrition - (Review Article)

Manary, M.J., Sandige, H.L. 2008. Management of acute moderate and severe childhood malnutrition. British Medical Journal. 337:1227-1230.

Postintervention growth of Malawian children who received 12-mo dietary complementation with a lipid-based nutrient supplement or maize-soy flour - (Peer Reviewed Journal)

Phuka, J.C., Maleta, K., Thakwalakwa, C., Cheung, Y.B., Briend, A., Manary, M.J., Ashorn, P. 2009. Postintervention growth of Malawian children who received 12-mo dietary complementation with a lipid-based nutrient supplement or maize-soy flour. American Journal of Clinical Nutrition. 89(1):382-390.

Complementary feeding with fortified spread and incidence of severe stunting in 6- to 18-month-old rural Malawians - (Peer Reviewed Journal)

Phuka, J.C., Maleta, K., Thakwalakwa, C., Cheung, Y.B., Briend, A., Manary, M.J., Ashorn, P. 2008. Complementary feeding with fortified spread and incidence of severe stunting in 6- to 18-month-old rural Malawians. Archives of Pediatrics and Adolescent Medicine. 162(7):619-626.

The use of home-based therapy with ready-to-use therapeutic food to treat malnutrition in a rural area during a food crisis - (Peer Reviewed Journal)

Amthor, R.E., Cole, S.M., Manary, M.J. 2009. The use of home-based therapy with ready-to-use therapeutic food to treat malnutrition in a rural area during a food crisis. Journal of The American Dietetic Association. 109(3):464-467.

Gastric emptying and postprandial glucose excursions in adolescents with type 1 diabetes - (Peer Reviewed Journal)

Heptulla, R.A., Rodriguez, L.M., Mason, K.J., Haymond, M.W. 2008. Gastric emptying and postprandial glucose excursions in adolescents with type 1 diabetes. Pediatric Diabetes. 9(6):561-566.

The test of variables of attention (TOVA): Internal consistency (Q1 vs. Q2 and Q3 vs. Q4) in children with Attention Deficit/Hyperactivity Disorder (ADHD) - (Peer Reviewed Journal)

Llorente, A.M., Voigt, R., Jensen, C.L., Fraley, J.K., Heird, W.C., Rennie, K.M. 2008. The test of variables of attention (TOVA): Internal consistency (Q1 vs. Q2 and Q3 vs. Q4) in children with Attention Deficit/Hyperactivity Disorder (ADHD). Child Neuropsychology. 14(4):314-322.

Bicarbonate kinetics and predicted energy expenditure in critically ill children - (Peer Reviewed Journal)

Sy, J., Gourishankar, A., Gordon, W.E., Griffin, D., Zurakowski, D., Roth, R.M., Coss-Bu, J., Jefferson, L., Heird, W., Castillo, L. 2008. Bicarbonate kinetics and predicted energy expenditure in critically ill children. American Journal of Clinical Nutrition. 88(2):340-347.

Adaptation to a long term (4 weeks) arginine- and precursor (glutamate, proline and aspartate)-free diet - (Peer Reviewed Journal)

(25-Apr-08)

Hyperglycemia during induction therapy is associated with increased infectious complications in childhood acute lymphocytic leukemia - (Peer Reviewed Journal)

Sonabend, R.Y., McKay, S.V., Okcu, M.F., Yan, J., Haymond, M.W., Margolin, J.F. 2008. Hyperglycemia during induction therapy is associated with increased infectious complications in childhood acute lymphocytic leukemia. Pediatric Blood and Cancer. 51(3):387-392

Enhancement of maternal lactation performance during prolonged lactation in the mouse by mouse GH and long-R3-IGF-I is linked to changes in mammary signaling and gene expression - (Peer Reviewed Journal)

Hadsell, D.L., Parlow, A.F., Torres, D., George, J., Olea, W. 2008. Enhancement of maternal lactation performance during prolonged lactation in the mouse by mouse GH and long-R3-IGF-I is linked to changes in mammary signaling and gene expression. Journal of Endocrinology. 198:61-70.

Protein and amino acid metabolism in the human newborn - (Review Article)

Kalhan, S.C., Bier, D.M. 2008. Protein and amino acid metabolism in the human newborn. Annual Review of Nutrition. 28:389-410.

Case management of HIV-infected severely malnourished children: challenges in the area of highest prevalence - (Review Article)

Heikens, G.T., Bunn, J., Amadi, B., Manary, M., Chhagan, M., Berkley, J.A., Rollins, N., Kelly, P., Adamczick, C., Maitland, K., Tomkins, A. 2008. Case management of HIV-infected severely malnourished children: Challenges in the area of highest prevalence. Lancet. 371(9620):1305-1307.

Infant feeding and vision - (Review Article)

Heird, W.C. 2008. Infant feeding and vision. American Journal of Clinical Nutrition. 87(5):1120.

Methionine splanchnic uptake is increased in critically ill children - (Abstract Only)

Sy, J., Gordon, W.E., Verbruggen, S., Wu, M., Castillo, L. 2008. Methionine splanchnic uptake is increased in critically ill children [abstract]. Journal of Federation of American Societies for Experimental Biology. 22:869.27.

Parenteral amino acid intakes in critically ill children - (Abstract Only)

Sy, J., Gordon, W.E., Verbruggen, S., Arrivillaga, A., Lane, C., Stein, F., Castillo, L. 2008. Parenteral amino acid intakes in critically ill children [abstract]. Journal of Federation of American Societies for Experimental Biology. 22:869.26.

Epigenetic modifications and chromatin loop organization explain the different expression profiles of the Tbrg4, WAP and Ramp3 genes - (Peer Reviewed Journal)

Montazer-Torbati, M.B., Hue-Beauvais, C., Droineau, S., Ballester, M., Coant, N., Aujean, E., Petitbarat, M., Rijnkels, M., Devinoy, E. 2008. Epigenetic modifications and chromatin loop organization explain the different expression profiles of the Tbrg4, WAP and Ramp3 genes. Experimental Cell Research. 314:975-987.

Nutrition interventions need improved operational capacity - (Review Article)

Heikens, G.T., Amadi, B.C., Manary, M., Rollins, N., Tomkins, A. 2008. Nutrition interventions need improved operational capacity. Lancet. 371(9608):181-182.

Feeding patterns of underweight children in rural Malawi given supplementary fortified spread at home - (Peer Reviewed Journal)

Flax, V.L., Ashorn, U., Phuka, J., Maleta, K., Manary, M.J., Ashorn, P. 2008. Feeding patterns of underweight children in rural Malawi given supplementary fortified spread at home. Maternal and Child Nutrition. 4(1):65-73.

Corticosteroids increase glutamine utilization in human splanchnic bed - (Peer Reviewed Journal)

Thibault, R., Welch, S., Mauras, N., Sager, B., Altomare, A., Haymond, M., Darmaun, D. 2008. Corticosteroids increase glutamine utilization in human splanchnic bed. American Journal of Physiology-Gastrointestinal and Liver Physiology. 294:G548-G553.

An energy-dense complementary food is associated with a modest increase in weight gain when compared with a fortified porridge in Malawian children aged 6-18 months - (Peer Reviewed Journal)

Lin, C.A., Manary, M.J., Maleta, K., Briend, A., Ashorn, P. 2008. An energy-dense complementary food is associated with a modest increase in weight gain when compared with a fortified porridge in Malawian children aged 6-18 months. Journal of Nutrition. 138(3):593-598.

Macronutrient requirement for growth: Protein/amino acid - (Book / Chapter)

Roth, R.M., Castillo, L. 2008. Macronutrient requirement for growth: Protein/amino acid. In: Duggan, C., Watkins, J.B., Walker, W.A., editors. Nutrition In Pediatrics. 4th edition. Hamilton, Ontario:BC Decker Inc. p. 49-58.

Enforced epithelial expression of IGF-1 causes hyperplastic prostate growth while negative selection is requisite for spontaneous metastogenesis - (Peer Reviewed Journal)

Kaplan-Lefko, P.J., Sutherland, B.W., Evagelou, A.I., Hadsell, D.L., Barrios, R.J., Foster, B.A., Demayo, F., Greenberg, N.M. 2008. Enforced epithelial expression of IGF-1 causes hyperplastic prostate growth while negative selection is requisite for spontaneous metastogenesis. Oncogene. 27(20):2868-2876.

Regulation of gene expression in human mammary epithelium: effect of breast pumping - (Peer Reviewed Journal)

Maningat, P.D., Sen, P., Sunehag, A.L., Hadsell, D.L., Haymond, M.W. 2007. Regulation of gene expression in human mammary epithelium: Effect of breast pumping. Journal of Endocrinology. 195(3):503-511.

The effect of total starvation and very low energy diet in lean men on kinetics of whole body protein and five hepatic secretory proteins. - (Peer Reviewed Journal)

Afolabi, P.R., Jahoor, F., Jackson, A.A., Stubbs, J., Johnstone, A.M., Faber, P., Lobley, G., Gibney, E., Elia, M. 2007. The effect of total starvation and very low energy diet in lean men on kinetics of whole body protein and five hepatic secretory proteins. American Journal of Physiology - Endocrinology and Metabolism. 293:E1580-E1589.

Measurement of gluconeogenesis using glucose fragments and mass spectrometry after ingestion of deuterium oxide. - (Peer Reviewed Journal)

Chacko, S.K., Sunehag, A.L., Sharma, S., Sauer, P.J.J., Haymond, M.W. 2008. Measurement of gluconeogenesis using glucose fragments and mass spectrometry after ingestion of deuterium oxide. Journal of Applied Physiology. 104:944-951.

Insulin therapy in the pediatric intensive care unit - (Review Article)

Verbruggen, S.C., Joosten, K.F., Castillo, L., Van Goudoever, J.B. 2007. Insulin therapy in the pediatric intensive care unit. Clinical Nutrition. 26(6):677-690.

Nutritional management of preterm infants postdischarge - (Book / Chapter)

Heird, W.C. 2008. Nutritional management of preterm infants postdischarge. In: Duggan, C., Watkins, J.B., Walker, W.A., editors. Nutrition In Pediatrics. 4th edition. Hamilton, ON: BC Decker Inc. p. 395-402.

The role of prandial pramlintide in the treatment of adolescents with type 1 diabetes - (Peer Reviewed Journal)

Rodriguez, L.M., Mason, K., Haymond, M.W., Heptulla, R.A. 2007. The role of prandial pramlintide in the treatment of adolescents with type 1 diabetes. Pediatric Research. 62(6):746-749.

Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development - (Peer Reviewed Journal)

Heckman, B.M., Chakravarty, G., Vargo-Gogola, T., Gonzales-Rimbau, M., Hadsell, D.L., Lee, A.V., Settleman, J., Rosen, J.M. 2007. Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development. Developmental Biology. 309:137-149.

A large-scale operational study of home-based therapy with ready-to-use therapeutic food in childhood malnutriton in Malawi - (Peer Reviewed Journal)

Linneman, Z., Matilsky, D., Ndekha, M., Manary, M.J., Maleta, K., Manary, M.J. 2007. A large-scale operational study of home-based therapy with ready-to-use therapeutic food in childhood malnutriton in Malawi. Maternal and Child Nutrition. 3(3):206-215.

Arginine flux and intravascular nitric oxide synthesis in severe childhood undernutrition - (Peer Reviewed Journal)

Jahoor, F., Badaloo, A., Villalpando, S., Reid, M., Forrester, T. 2007. Arginine flux and intravascular nitric oxide synthesis in severe childhood undernutrition. American Journal of Clinical Nutrition. 86(4):1024-1031.

Formative research of a quick list for an automated self-administered 24-Hour dietary recall - (Peer Reviewed Journal)

Subar, A.F., Thompson, F.E., Potischman, N., Forsyth, B.H., Buday, R., Richards, D., McNutt, S., Hull, S.G., Guenther, P.M., Schatzkin, A., Baranowski, T. 2007. Formative research of a quick list or an automated self-administered 24-hour dietary recall. Journal of The American Dietetic Association. 107(6):1002-1007.

Understanding and interpreting laboratory test results in the clinical management of diabetes mellitus - (Review Article)

Jeha, G., Haymond, M.W. 2007. Understanding and interpreting laboratory test results in the clinical management of diabetes mellitus. Pediatric Endocrinology Reviews. 5(suppl.1):608-628.

Ethnic/racial diversity, maternal stress, lactation and very low birthweight infants - (Peer Reviewed Journal)

Lau, C., Hurst, N.M., Smith, E.O., Schanler, R.J. 2007. Ethnic/racial diversity, maternal stress, lactation and very low birthweight infants. Journal of Perinatology. 27(7):399-408.

Comparison of the validity of direct pediatric developmental evaluation versus developmental screening by parent report - (Peer Reviewed Journal)

Voight, R.G., Llorente, A.M., Jensen, C., Fraley, J.K., Barbaresi, W.J., Heird, W.C. 2007. Comparison of the validity of direct pediatric developmental evaluation versus developmental screening by parent report. Journal of Clinical Pediatrics. 46(6):523-529.

Rapid resolution of consumptive hypothyroidism in a child with hepatic hemangioendothelioma following liver transplantation - (Peer Reviewed Journal)

Balazs, A.E., Athanassaki, I., Gunn, S.K., Tatevian, N., Huang, S.A., Haymond, M.W., Karaviti, L.P. 2007. Rapid resolution of consumptive hypothyroidism in a child with hepatic hemangioendothelioma following liver transplantation. Annals of Clinical and Laboratory Science. 37(3):280-284.

Methionine cycle kinetics and arginine supplementation in endothelial dysfunction of ESRD - (Abstract Only)

Pendse, S., Singh, A., Swain, J., Creager, M., Gerhard, M., Castillo, L. 2007. Methionine cycle kinetics and arginine supplementation in endothelial dysfunction of ESRD [abstract]. Journal of Federation of American Societies for Experimental Biology. 21(6):A1404.

Methionine requirements in healthy adolescents - (Abstract Only)

Gordon, W.E., Sy, J., Zurakowski, D., Griffin, D., Jefferson, L., Castillo, L. 2007. Methionine requirements in healthy adolescents [abstract]. Journal of Federation of American Societies for Experimental Biology. 21(5):A334-A335.

Parenteral sulfur amino acid requirements in septic infants - (Abstract Only)

Sy, J., Gordon, W., Griffin, D., Jefferson, L.S., Krance, R.A., Heird, W., Castillo, L. 2007. Parenteral sulfur amino acid requirements in septic infants [abstract]. Journal of Federation of American Societies for Experimental Biology. 21(6):A1072.

Oncogenic transformation by the signaling adaptor proteins insulin receptor substrate (IRS)-1 and IRS-2     - (Review Article)

Dearth, R.K., Cui, X., Kim, H., Hadsell, D.L., Lee, A.V. 2007. Oncogenic transformation by the signaling adaptor proteins insulin receptor substrate (IRS)-1 and IRS-2. Cell Cycle. 6(6):705-713.

The declining phase of lactation: Peripheral or central, programmed or pathological? - (Review Article)

Hadsell, D., George, J., Torres, D. 2007. The declining phase of lactation: Peripheral or central, programmed or pathological? Journal of Mammary Gland Biology and Neoplasia. 12:59-70.

Progress in promoting breast-feeding, combating malnutrition, and composition and use of infant formula, 1981-2006 - (Review Article)

Heird, W.C. 2007. Progress in promoting breast-feeding, combating malnutrition, and composition and use of infant formula, 1981-2006. Journal of Nutrition. 137:499S-502S.

Nutritional Needs - (Book / Chapter)

Heird, W.C. 2007. Nutritional needs. In: Kliegman, R.M., Jenson, H.B., Behrman, R.E., Stanton, B.F., editors. Nelson Textbook of Pediatrics. 18th edition. Saunders Elsevier, Philadelphia, PA. p. 209-214.

The feeding of infants and children - (Book / Chapter)

Heird, W.C. 2007. The feeding of infants and children. In: Kliegman, R.M., Jenson, H.B., Behrman, R.E., Stanton, B.F., editors. Nelson Textbook of Pediatrics. 18th edition. Saunders Elsevier, Philadelphia, PA. p. 214-225.

Food insecurity, hunger, and undernutrition - (Book / Chapter)

Heird, W.C. 2007. Food insecurity, hunger, and undernutrition. In: Kliegman, R.M., Jenson, H.B., Behrman, R.E., Stanton, B.F., editors. Nelson Textbook of Pediatrics. 18th edition. Saunders Elsevier, Philadelphia. PA. p. 226-232.

A prospective assessment of food and nutrient intake in a population of Malawian children at risk for kwashiorkor - (Peer Reviewed Journal)

Lin, C.A., Boslaugh, S., Ciliberto, H.M., Maleta, K., Ashorn, P., Briend, A., Manary, M.J. 2007. A prospective assessment of food and nutrient intake in a population of Malawian children at risk for kwashiorkor. Journal of Pediatric Gastroenterology and Nutrition. 44(4):487-493.

Acute depletion of plasma glutamine increases leucine oxidation in prednisone-treated humans. - (Peer Reviewed Journal)

Le Bacquer, O., Mauras, N., Welch, S., Haymond, M., Darmaun, D. 2007. Acute depletion of plasma glutamine increases leucine oxidation in prednisone-treated humans. Clinical Nutrition. 26:231-238.

Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2 - (Review Article)

Dearth, R.K., Cui, X., Kim, H., Kuiatse, I., Lawrence, N.A., Zhang, X., Divisova, J., Britton, O.L., Mohsin, S., Allred, D.C., Hadsell, D.L., Lee, A.V. 2006. Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2. Molecular and Cellular Biology. 26:9302-9314.

Local production and provision of ready-to-use therapeutic food (RUTF) spread for the treatment of severe childhood malnutrition - (Peer Reviewed Journal)

Manary, M.J. 2006. Local production and provision of ready-to-use therapeutic food (RUTF) spread for the treatment of severe childhood malnutrition. Food and Nutrition Bulletin. 27(3 Suppl):S83-S89.

Integration of prolactin and glucocorticoid signaling at the beta-casein promoter and enhancer by ordered recruitment of specific transcription factors and chromatin modifiers     - (Peer Reviewed Journal)

Kabotyanski, E.B., Huetter, M., Xian, W., Rijnkels, M., Rosen, J. M. 2006. Integration of prolactin and glucocorticoid signaling at the beta-casein promoter and enhancer by ordered recruitment of specific transcription factors and chromatin modifiers. Molecular Endocrinology. 20:2355-2368.

Osteopenic effects of MgSO4 in multiple pregnancies. - (Peer Reviewed Journal)

Kaplan, W., Haymond, M., McKay, S., Karaviti, L.P. 2006. Osteopenic effects of MgSO4 in multiple pregnancies. Journal of Pediatric Endocrinology & Metabolism. 19(10):1225-1230.

Sulfur amino acid metabolism in children with severe childhood undernutrition: methionine kinetics - (Peer Reviewed Journal)

Jahoor, F., Badaloo, A., Reid, M., Forrester, T. 2006. Sulfur amino acid metabolism in children with severe childhood undernutrition: Methionine kinetics. American Journal of Clinical Nutrition. 84(6):1400-1405.

Effects of transgenic expression of HIV-1 Vpr on lipid and energy metabolism in mice - (Peer Reviewed Journal)

Balasubramanyam, A., Mersmann, H., Jahoor, F., Phillips, T.M., Sekhar, R.V., Schubert, U., Brar, B., Iyer, D., Smith, E.O., Takahashi, H., Lu, H., Anderson, P., Kino, T., Henklein, P., Kopp, J.B. 2007. Effects of transgenic expression of HIV-1 Vpr on lipid and energy metabolism in mice. American Journal of Physiology - Endocrinology and Metabolism. 292(1):E40-E48.

Growth and change in blood haemoglobin concentration among underweight Malawian infants receiving fortified spreads for 12 weeks: a preliminary trial - (Peer Reviewed Journal)

Kuusipalo, H., Maleta, K., Briend, A., Manary, M., Ashorn, P. 2006. Growth and change in blood haemoglobin concentration among underweight Malawian infants receiving fortified spreads for 12 weeks: A preliminary trial. Journal of Pediatric Gastroenterology and Nutrition. 43(4):525-532.

Treatment and complications of diabetic ketoacidosis in children - (Other)

Jeha, G., Haymond, M.W. 2006. Treatment and complications of diabetic ketoacidosis in children. In: Rose, B.D., editors. UpToDate Online Journal [serial online]. Available: http://www.uptodate.com.

Lipid kinetic differences between children with kwashiorkor and those with marasmus 1-3 - (Peer Reviewed Journal)

Badaloo, A.V., Forrester, T., Reid, M., Jahoor, F. 2006. Lipid kinetic differences between children with kwashiorkor and those with marasmus 1-3. The American Journal of Clinical Nutrition. 83:1283-1288.

THE QUALITY OF THE DIET IN MALAWIAN CHILDREN WITH KWASHIORKOR AND MARASMUS - (Peer Reviewed Journal)

Sullivan, J., Ndekha, M., Maker, D., Hotz, C., Manary, M.J. 2006. The quality of the diet in Malawian children with kwashiorkor and marasmus. Maternal and Child Nutrition. 2(2):114-122.

Glycine production in severe childhood undernutrition - (Peer Reviewed Journal)

Jahoor, F., Badaloo, A., Reid, M., Forrester, T. 2006. Glycine production in severe childhood undernutrition. American Journal of Clinical Nutrition. 84:143-149.

In vivo arginine production and intravascular nitric oxide synthesis in hypotensive sepsis - (Peer Reviewed Journal)

Villalpando, S., Gopal, J., Balasubramanyam, A., Bandi, V.P., Guntupalli, K., Jahoor, F. 2006. In vivo arginine production and intravascular nitric oxide synthesis in hypotensive sepsis. American Journal of Clinical Nutrition. 84(1):197-203.

Physiologic growth hormone replacement improves fasting lipid kinetics in patients with HIV lipodystrophy syndrome - (Peer Reviewed Journal)

D'Amico, S., Shi, J., Sekhar, R.V., Jahoor, F., Ellis, K.J., Rehman, K., Willis, J., Maldonado, M., Balasubramanyam, A. 2006. Physiologic growth hormone replacement improves fasting lipid kinetics in patients with HIV lipodystrophy syndrome. American Journal of Clinical Nutrition. 84(1):204-211.

Decreased lactation capacity and altered milk composition in IRS-1 knockout mice is associated with decreased insulin-dependent phosphorylation of Akt. - (Abstract Only)

Hadsell, D.L., Lawrence, N.A., George, J., Torres, D.T., Lee, A.V. 2006. Decreased lactation capacity and altered milk composition in IRS-1 knockout mice is associated with decreased insulin-dependent phosphorylation of Akt [abstract]. Endocrine Society Meeting. Available: http://www.abstracts2view.com/endo/view.php?nu=ENDO06L_P1-435.

The growth hormone receptor antagonist pegvisomant blocks both mammary gland development and MCF-7 breast cancer xenograft growth. - (Peer Reviewed Journal)

Divisova, J., Kuiatse, I., Lazard, Z., Weiss, H., Vreeland, F., Hadsell, D.L., Schiff, R., Osborne, C.K., Lee, A.V. 2006. The growth hormone receptor antagonist pegvisomant blocks both mammary gland development and MCF-7 breast cancer xenograft growth. Breast Cancer Research and Treatment. 98(3):315-327.

A noncoding RNA is a potential marker of cell fate during mammary gland development - (Peer Reviewed Journal)

Ginger, M.R., Shore, A.N., Contreras, A., Rijnkels, M., Miller, J., Gonzalez-Rimbau, M.F., Rosen, J.M. 2006. A noncoding RNA is a potential marker of cell fate during mammary gland development. Proceedings of the National Academy of Sciences. 103(15):5781-5786.

Unique metabolic characteristics of the major syndromes of severe childhood malnutrition - (Book / Chapter)

Jahoor, F., Badaloo, A., Reid, M., Forrester, T. 2006. Unique metabolic characteristics of the major syndromes of severe childhood malnutrition. In: Picou, D., Forrester, T., Walker, S.P., editors. The Tropical Metabolism Research Unit, the University of the West Indies Jamaica 1956-2006. The House that John Built. Kingston: Ian Randle Publishers. p. 25-60.

HOME-BASED THERAPY FOR OEDEMATOUS MALNUTRITION WITH READY-TO-USE THERAPEUTIC FOOD - (Peer Reviewed Journal)

Ciliberto, M.A., Manary, M.J., Ndekha, M.J., Briend, A., Ashorn, P. 2006. Home-based therapy for oedematous malnutrition with ready-to-use therapeutic food. Acta Paediatrica. 95(8):1012-1015.

In vivo rates of erythrocyte glutathione synthesis in adults with sickle cell disease - (Peer Reviewed Journal)

Reid, M., Badaloo, A., Forrester, T., Jahoor, F. 2006. In vivo rates of erythrocyte glutathione synthesis in adults with sickle cell disease. American Journal of Physiology Endocrinology and Metabolism. 291:E73-E79.

DONOR MILK: DOWN BUT NOT OUT (IN REPLY) - (Other)

Schanler, R.J., Lau, C., Hurst, N.M., Smith, E.O. 2005. Donor milk: Down but not out (In reply). Pediatrics. 116(6):1610.

SUPPLEMENTAL FEEDING WITH READY-TO-USE THERAPEUTIC FOOD IN MALAWIAN CHILDREN AT RISK OF MALNUTIRITON - (Peer Reviewed Journal)

Patel, M.P., Sandige, H.L., Ndekha, M.J., Briend, A., Ashorn, P., Manary, M.J. 2005. Supplemental feeding with ready-to-use therapeutic food in Malawian children at risk of malnutrition. Journal of Health, Population, and Nutrition. 23(4):351-357.

INCREASED LIVER PATHOLOGY IN HEPATITIS C VIRUS TRANSGENIC MICE EXPRESSING THE HEPATITIS B VIRUS X PROTEIN - (Peer Reviewed Journal)

Keasler, V.V., Lerat, H., Madden, C.R., Finegold, M.J., McGarvey, M.J., Mohammed, E.M., Forbes, S.J., Lemon, S.M., Hadsell, D.L., Grona, S.J., Hollinger, F.B., Slagle, B.L. 2006. Increased liver pathology in hepatitis C virus transgenic mice expressing the hepatitis B virus X protein. Virology. 346(2):466-475.

Pathophysiology of adipocyte defects and dyslipidemia in HIV lipodystrophy: New evidence from metabolic and molecular studies - (Peer Reviewed Journal)

Balasubramanyam, A., Sekhar, R.V., Jahoor, F., Pownall, H.J., Lewis, D. 2006. Pathophysiology of adipocyte defects and dyslipidemia in HIV lipodystrophy: New evidence from metabolic and molecular studies. American Journal of Infectious Diseases. 2(3):167-172.

Protein and amino acid metabolism and requirements - (Book / Chapter)

Heird, W.C., Kashyap, S. 2006. Protein and amino acid metabolism and requirements. In: Polin, R.A., Fox, W.W., Abman, S.H., editors. Fetal and Neonatal Physiology. 3rd edition. Philadelphia, PA: W.B. Sanders. p. 527-539.

MULTIFUNCTIONAL ROLES OF LACTOFERRIN: A CRITICAL OVERVIEW - (Review Article)

Ward, P.P., Paz, E., Conneely, O.M. 2005. Multifunctional roles of lactoferrin: a critical overview. Cellular and Molecular Life Sciences. 62(22):2540-2548.

Nutrient requirements of term and preterm infants - (Book / Chapter)

Heird, W.C. 2006. Nutrient requirements of term and preterm infants. In: Burg, F.D., Ingelfinger, J.R., Polin, R.A., Gershon, A.A., editors. Current Pediatric Therapy. 18th edition. Philadelphia, PA: Saunders Elsevier. p. 66-71.

OVEREXPRESSION OF DES(1-3) INSULIN-LIKE GROWTH FACTOR 1 IN THE MAMMARY GLANDS OF TRANSGENIC MICE DELAYS THE LOSS OF MILK PRODUCTION WITH PROLONGED LACTATION - (Peer Reviewed Journal)

Hadsell, D.L., Torres, D.T., Lawrence, N.A., George, J., Parlow, A.F., Lee, A.V., Fiorotto, M.L. 2005. Overexpression of des(1-3) insulin-like growth factor 1 in the mammary glands of transgenic mice delays the loss of milk production with prolonged lactation. Biology of Reproduction. 73:1116-1125.

Protein kinetic differences between children with edematous and nonedematous severe childhood undernutrition in the fed and postabsorptive states - (Peer Reviewed Journal)

Jahoor, F., Badaloo, A., Reid, M., Forrester, T. 2005. Protein kinetic differences between children with edematous and nonedematous severe childhood undernutrition in the fed and postabsorptive states. The American Journal of Clinical Nutrition. 82:792-800.

MEASUREMENT OF NITRIC OXIDE PRODUCTION IN HUMANS USING 15N-ARGININE AND TANDEM LC/MS - (Abstract Only)

(01-Jun-05)

SEVERELY DYSREGULATED DISPOSAL OF POSTPRANDIAL TRIACYLGLYCEROLS EXACERBATES HYPERTRIACYLGYCEROLEMIA IN HIV LIPODYSTROPHY SYNDROME - (Peer Reviewed Journal)

Sekhar, R.V., Jahoor, F., Pownall, H.J., Rehman, K., Gaubatz, J., Iyer, D., Balasubramanyam, A. 2005. Severely dysregulated disposal of postprandial triacylglycerols exacerbates hypertriacylgycerolemia in HIV lipodystrophy syndrome. American Journal of Clinical Nutrition. 81:1405-1410.

MODERATE TO SEVERE DEPRESSIVE SYMPTOMS AMONG ADOLESCENT MOTHERS FOLLOWED FOUR YEARS POSTPARTUM - (Peer Reviewed Journal)

Schmidt, R.M., Wiemann, C.M., Rickert, V.I., Smith, E.O. 2006. Moderate to severe depressive symptoms among adolescent mothers followed four years postpartum. Journal of Adolescent Health. 38(6):712-718.

Decreased lactation capacity and altered milk composition in insulin receptor substrate null mice is associated with decreased maternal body mass and reduced insulin-dependent phosphorylation of mammary Akt     - (Peer Reviewed Journal)

Hadsell, D.L., Olea, W., Lawrence, N., George, J., Torres, D., Kadowaki, T., Lee, A.V. 2007. Decreased lactation capacity and altered milk composition in insulin receptor substrate null mice is associated with decreased maternal body mass and reduced insulin-dependent phosphorylation of mammary Akt. Journal of Endocrinology. 194:327-336.

EVOLUTION AND REGULATION OF THE CASEIN GENE CLUSTER REGION: A GENOMICS APPROACH - (Abstract Only)

Rijnkels, M., Le, T., Thomas, J. 2005. Evolution and regulation of the casein gene cluster region: a genomics approach. Journal of Dairy Science. 88(Suppl. 1):76-77.

IDENTIFICATION OF FUNCTIONAL ELEMENTS IN A MAMMALIAN SPECIFIC GENE CLUSTER - (Abstract Only)

Kabotyanski, E., Le, T., Elnitski, L., Miller, W., Rosen, J.M., Rijnkels, M. 2004. Identification of functional elements in a mammalian specific gene cluster [abstract]. Cold Spring Harbor Meeting. p. 51.

The role of essential fatty acids in development - (Review Article)

Heird, W.C., Lapillonne, A. 2005. The role of essential fatty acids in development. Annual Review of Nutrition. 25:549-571.

Overexpression of des(1-3)hIGF-I in the mammary gland during prolonged lactation enhances milk yield and elevates prolactin secretion - (Abstract Only)

Hadsell, D.L., Torres, D., George, J., Shelton, G.S., Parlow, A.F., Fiorotto, M.L. 2005. Overexpression of des(1-3)hIGF-I in the mammary gland during prolonged lactation enhances milk yield and elevates prolactin secretion [abstract]. In: The 87th Annual Meeting of the Endocrine Society, June 4-7, 2005, San Diego, California. p. 531.

INCREASED MAMMARY GLAND OXIDATIVE DAMAGE AND APOPTOSIS DURING PROLONGED LACTATION IN THE MOUSE IS LITTLE AFFECTED BY OVEREXPRESSION OF DES(1-3)HIGF-I. - (Abstract Only)

Hadsell, D., Torres, D., George, J. 2005. Increased mammary gland oxidative damage and apoptosis during prolonged lactation in the mouse is little affected by overexpression of des(1-3)hIGF-I [abstract]. Journal of Dairy Science. 88(Suppl. 1):77.

MILKING THE GENOME: IDENTIFICATION OF FUNCTIONAL ELEMENTS IN A MAMMALIAN SPECIFIC GENE CLUSTER. - (Abstract Only)

Rijnkels, M., Kabotyanski, E., Le, T., Rosen, J.M. 2005. Milking the genome: identification of functional elements in a mammalian specific gene cluster [abstract]. 24th Summer Symposium in Molecular Biology; Comparative and Functional Genomics, July 20-23, 2005, Pennsylvania State University, University Park, Pennsylvanai. p. 89.

Clinical features and diagnosis of diabetic ketoacidosis in children - (Other)

Jeha, G., Haymond, M.W., 2005. Clinical features and diagnosis of diabetic ketoacidosis in children. UpToDate.com. Rose B.D., Wellesley, MA: Up To Date. Available: http://www.uptodate.com.

CHANGES IN SECRETORY CELL TURNOVER, AND MITOCHONDRIAL OXIDATIVE DAMAGE IN THE MOUSE MAMMARY GLAND DURING A SINGLE PROLONGED LACTATION CYCLE SUGGEST THE POSSIBILITY OF ACCELERATED CELLULAR AGING. - (Peer Reviewed Journal)

Hadsell, D.L., Torres, D., George, J., Capuco, A.V., Ellis, S.E., Fiorotto, M.L. 2006. Changes in secretory cell turnover, and mitochondrial oxidative damage in the mouse mammary gland during a single prolonged lactation cycle suggest the possibility of accelerated cellular aging. Experimental Gerontology. 41(3):271-281.

Use of a novel pediatric body composition technique for assessing body fatness and its changes during the first 6 month of life     - (Abstract Only)

Yao, M., Heird, W.C., Wong, W.W., Shypailo, R.J., Urlando, A., Ellis, K.J. 2005. Use a novel pediatric body composition technique for assessing body fatness and its changes during the first 6 month of life [abstract]. Pediatric Academic Society. 57:1458.

THE ROLE OF SUBCUTANEOUS PRAMLINTIDE INFUSION IN THE TREATMENT OF ADOLESCENTS WITH TYPE 1 DIABETES - (Abstract Only)

Heptulla, R.A., Rodriguez, L.M., Bomgaars, L., Mason, K., Haymond, M.W. 2005. The role of subcutaneous pramlintide infusion in the treatment of adolescents with type 1 diabetes [abstract]. American Diabetes Association 65th Annual Meeting. Paper No. 447-P.

UNDERSTANDING THE REGULATION OF A MAMMALIAN-SPECIFIC GENOMIC DOMAIN ENCODING SECRETED PROTEINS - (Abstract Only)

Kabotyanski, E., Kemp, L., Rosen, J.M., Rijnkels, M. 2005. Understanding the regulation of a mammalian-specific genomic domain encoding secreted proteins [abstract]. Systems Biology: Genomic Approaches to Transcription Regulation. Cold Spring Harbor Meeting. p. 61.

TUMOR DEVELOPMENT BY TRANSGENIC EXPRESSION OF A CONSTITUTIVELY ACTIVE INSULIN-LIKE GROWTH FACTOR I RECEPTOR - (Peer Reviewed Journal)

Carboni, J.M., Lee, A.V., Hadsell, D.L., Rowley, B.R., Lee, F.Y., Bol, D.K., Camuso, A.E., Gottardis, M., Ho, C., Hurlburt, W. 2005. Tumor development by transgenic expression of a constitutively active Insulin-Like Growth Factor I receptor. Cancer Research. 65:3781-3781.

ARE THE METABOLIC EFFECTS OF GH AND IGF-I SEPARABLE? - (Peer Reviewed Journal)

Mauras, N., Haymond, M.W. 2005. Are the metabolic effects of GH and IGF-I separable? Growth Hormone and IGF Research. 15(1):19-27.

COMPARISON OF HOME-BASED THERAPY WITH READY-TO-USE THERAPEUTIC FOOD WITH STANDARD THERAPY IN THE TREATMENT OF MALNOURISHED MALAWIAN CHILDREN: A CONTROLLED, CLINICAL EFFECTIVENESS TRIAL - (Peer Reviewed Journal)

Ciliberto, M.A., Sandige, H., Ndekha, M.J., Ashorn, P., Briend, A., Ciliberto, H.M., Manary, M.J. 2005. Comparison of home-based therapy with ready-to-use therapeutic food with standard therapy in the treatment of malnourished Malawian children: a controlled, clinical effectiveness trial. American Journal of Clinical Nutrition. 81(4):864-870.

SEQUENCE AND COMPARATIVE ANALYSIS OF THE CHICKEN GENOME PROVIDE UNIQUE PERSPECTIVES ON VERTEBRATE EVOLUTION. - (Peer Reviewed Journal)

Hillier, L.W., Miller, W., Birney, E., Warren, W., Hardison, R.C., Ponting, C.P., Bork, P., Burt, D.W., Groenen, M.A., Rijnkels, M. 2004. Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature. 432:695-716.

Taurine in neonatal nutrition - revisited - (Other)

Heird, W.C. 2004. Taurine in neonatal nutrition - revisited. Archives of Disease in Childhood: Retal and Neonatal Edition. 89:F472-F473.

Nutrition in pediatrics: basic science and clinical applications - (Review Article)

Heird, W.C. 2004. Nutrition in pediatrics: Basic science and clinical applications. American Journal of Clinical Nutrition. 80(4):1091.

MAMMARY GLAND-SPECIFIC OVEREXPRESSION OF INSULIN RECEPTOR SUBSTRATE-1 AND -2 HAS MINIMAL IMPACT ON DOWNSTREAM KINASE ACTIVITY AND DOESN'T AFFECT MAMMARY INVOLUTION - (Abstract Only)

Hadsell, D.L., Divisova, J., Cui, X., Lawrence, N.A., Lee, A.V. 2004. Mammary gland-specific overexpression of insulin receptor substrate-1 and -2 has minimal impact on downstream kinase activity and doesn't affect mammary involution [abstract]. In: Endocrine Society Meeting Proceedings, June 16-19, 2004, New Orleans, Louisiana. Abstract P3-37. p. 473.

DIFFERENTIAL ABILITY OF INSULIN AND LONG-R3-IGF-I TO INDUCE AKT PHOSPHORYLATION IN MAMMARY GLAND OF THE VIRGIN MOUSE IS ACCOUNTED FOR BY CELLULAR HETEROGENEITY. - (Abstract Only)

Hadsell, D.L., George, J., Lawrence, N., Torres, D., Fiorotto, M. 2004. Differential ability of insulin and long-r3-IGF-I to induce Akt phosphorylation in mammary gland of the virgin mouse is accounted for by cellular heterogeneity [abstract]. In: Endocrine Society Meeting Proceedings, June 16-19, 2004, New Orleans, Louisiana. Abstract P3-177. p. 507-508.

Nutritional management of infants and children with specific diseases or other conditions - (Book / Chapter)

Cooper, A., Heird, W.C. 2006. Nutritional management of infants and children with specific diseases or other conditions. In: Shils, M.E., Shike, M., Ross, A.C., Caballero, B., Cousins, R.J., editors. Modern Nutrition in Health and Disease. 10th edition. Baltimore, MD: Lippincott Williams & Wilkins. p. 991-1003.

Infancy and childhood - (Book / Chapter)

Heird, W.C., Cooper, A. 2006. Infancy and childhood. In: Shils, M.E., Shike, M., Ross, A.C., Caballero, B., Cousins, R.J., editors. Modern Nutrition in Health and Desease. 10th edition. Baltimore, MD: Lippincott Williams & Wilkins. p. 797-817.

FUNCTIONAL GENOMICS OF THE CASEINS - (Abstract Only)

Rijnkels, M. 2004. Functional genomics of the caseins. Meeting Proceedings of the 18th Annual J.R. Brunner Symposium at Michigan State University, East Lansing, MI (5/20-21/2004).

Lactation persistence is enhanced in transgenic mice overexpressing des(1-3)hIGF-I in the mammary gland - (Abstract Only)

Hadsell, D.L., Torres, D.T., George, J., Shelton, G.S., Fiorotto, M.L. 2004. Lactation persistence is enhanced in transgenic mice overexpressing des(1-3)hIGF-I in the mammary gland [abstract]. Journal of Animal Science Supplement. 82(Suppl. 1):204.

The role of essential fatty acids in development - (Book / Chapter)

Heird, W.C. 2006. The role of essential fatty acids in development. In: Thureen, P., Hay, W., editors. Neonatal Nutrition and Metabolism. 2nd edition. New York, NY: Cambridge University Press. p. 147-160.

Intravenous feeding - (Book / Chapter)

Heird, W.C. 2006. Intravenous feeding. In: Thureen, P., Hay, W., editors. Neonatal Nutrition and Metabolism. 2nd Edition. NY: Cambridge University Press. p. 312-331.

Effects of maternal docosahexaenoic acid (DHA) supplementation on neuropsychological and visual status of former breast-fed infants at five years of age - (Abstract Only)

Jensen, C., Voigt, R., Llorente, A., Peters, S., Prager, T., Zou, Y., Fraley, K., Heird, W. 2004. Effects of maternal docosahexaenoic acid (DHA) supplementation on neuropsychological and visual status of former breast-fed infants at five years of age [abstract]. Pediatric Research. 55(4):181A.

Polyunsaturated fatty acids and gene expression - (Review Article)

Lapillone, A., Clarke, S.D., Heird, W.C. 2004. Polyunsaturated fatty acids and gene expression. Current Opinion in Clinical Nutrition and Metabolic Care. 7:151-156.

Reply: Omega-3 polyunsaturated fatty acids for postpartum depression - (Other)

Llorente, A., Jensen, C.L., Heird, W.C. 2004. Reply: Omega-3 polyunsaturated fatty acids for postpartum depression. American Journal of Obstetrics and Gynecology. 190:583.

Nutritional requirements - (Book / Chapter)

Heird, W.C. 2004. Nutritional requirements. In: Behrman, R.E., Kleigman, R. M., Jenson, H. B., editors. Nelson Textbook of Pediatrics. 17th edition. Philadelphia, PA: W.B. Sanders. p. 153-157.

The feeding of infants and children - (Book / Chapter)

Heird, W.C. 2004. The feeding of infants and children. In: Behrman, R.E., Kleigman, R.M., Jenson, H.B., editors. Nelson Textbook of Pediatrics. 17th edition. Philadelphia, PA: W.B. Sanders. p. 157-167.

Food insecurity, hunger, and undernutrition - (Book / Chapter)

Heird, W.C. 2004. Food insecurity, hunger, and undernutrition. In: Behrman, R.E., Kleigman, R.M., Jenson, H.B., editors. Nelson Textbook of Pediatrics. 17th edition. Philadelphia, PA: W.B. Sanders. p. 167-173.

Vitamin deficiencies and excesses - (Book / Chapter)

Heird, W.C. 2004. Vitamin deficiencies and excesses. In: Behrman, R.E., Kleigman, R.M., Jenson, H.B., editors. Nelson Textbook of Pediatrics. 17th edition. Philadelphia, PA: W.B. Sanders. p. 177-190.

Long-chain polyunsaturated fatty acids in chronic childhood disorders: panacea, promising, or placebo - (Other)

Agostoni, C., Heird, W.C. 2004. Long-chain polyunsaturated fatty acids in chronic childhood disorders: panacea, promising, or placebo. Journal of Pediatric Gastroenterology and Nutrition. 38(1):2-3.

Estrogen-mediated down-regulation of E-cadherin in breast cancer cells - (Peer Reviewed Journal)

Oesterreich, S., Deng, W., Jiang, S., Cui, X., Ivanova, M., Schiff, R., Kang, K., Hadsell, D.L., Behrens, J., Lee, A.V. 2003. Estrogen-mediated down-regulation of E-cadherin in breast cancer cells. Cancer Research. 63:5203-5208.

The insulin-like growth factor system in normal mammary gland function - (Review Article)

Hadsell, D. 2003. The insulin-like growth factor system in normal mammary gland function. Breast Disease. 17:3-14.

Fats and fatty acids - (Book / Chapter)

Heird, W.C. 2004. Fats and fatty acids. In: Kleinman, R.E. editor. Pediatric Nutrition Handbook. 5th Edition. Elk Grove Village. American Academy Press. p. 261-284.

MEASURING INSULIN RESISTANCE: A TASK WORTH DOING. BUT HOW? - (Review Article)

Haymond, M.W. 2003. Measuring insulin resistance: A task worth doing. But how? Pediatric Diabetes. 4(3):115-118.