Publications (Clicking on the reprint icon will take you to the publication reprint.)

Carbohydrate maldigestion induces necrotizing enterocolitis in preterm pigs - (Peer Reviewed Journal)

Thymann, T., Moller, H.K., Stoll, B., Stoy, A.C., Buddington, R.K., Bering, S., Jensen, B.B., Olutoye, O.O., Siggers, R.H., Molbak, L., Sangild, P.T., Burrin, D.G. 2010. Carbohydrate maldigestion induces necrotizing enterocolitis in preterm pigs. American Journal of Physiology. 297:G1115-G1125.

Intestinal metabolism of sulfur amino acids - (Review Article)

Bauchart-Thevret, C., Stoll, B., Burrin, D.G. 2009. Intestinal metabolism of sulfur amino acids. Nutrition Research Reviews. 22:175-187.

Glucagon-like peptide-2 increases splanchnic blood flow acutely in calves but loses effectiveness with chronic exposure     - (Abstract Only)

Taylor, C.C., Burrin, D.G., Holst, J.J., Mcleod, K.R., Harmon, D.L. 2009. Glucagon-like peptide-2 increases splanchnic blood flow acutely in calves but loses effectiveness with chronic exposure. Joint Meeting of the ADSA, AMSA, ASAS and PSA. Journal of Animal Science. 87:234 (E-Suppl. 2).

Can non-invasive measurement of gut oxygenation predict necrotizing enterocolitis in preterm infants?     - (Abstract Only)

Patel, A.K., Olutoye, O., Burrin, D.G., Brandt, M.L. 2009. Can non-invasive measurement of gut oxygenation predict necrotizing enterocolitis in preterm infants [abstract]? Proceedings of the Pediatric Academic Societies Annual Meeting, May 2-5, 2009, Baltimore, Maryland. Paper No. 4350.356.

The role of methionine metabolism in inflammatory bowel disease     - (Abstract Only)

Benight, N.M., Stoll, B., Puiman, P., Burrin, D. 2009. The role of methionine metabolism in inflammatory bowel disease [abstract]. Journal of Federation of American Societies for Experimental Biology. 23:919.6

Modulating the gut flora alters amino acid metabolism in neonatal pigs - (Abstract Only)

Puiman, P., Burrin, D., Van Goudoever, J., Boehm, G., Stoll, B. 2009. Modulating the gut flora alters amino acid metabolism in neonatal pigs [abstract]. Journal of Federation of American Societies for Experimental Biology. 23:919.9.

Arginine-mediated stimulation of intestinal epithelial cell protein synthesis is mTOR-dependent but NO-independent - (Abstract Only)

Bauchart-Thevret, C., Cui, L., Stoll, B., Burrin, D. 2009. Arginine-mediated stimulation of intestinal epithelial cell protein synthesis is mTOR-dependent but NO-independent [abstract]. Journal of Federation of American Societies for Experimental Biology. 23:227.7.

eNOS signaling is essential in GLP-2-mediated stimulation of blood flow, but not cell proliferation in the mouse gut - (Abstract Only)

Guan, X., Wang, Y., Li, X., Burrin, D., Li, D. 2009. eNOS signaling is essential in GLP-2-mediated stimulation of blood flow, but not cell proliferation in the mouse gut [abstract]. Journal of Federation of American Societies for Experimental Biology. 23:919.10

Sulfur amino acid deficiency upregulates intestinal methionine cycle activity and suppresses epithelial growth in neonatal pigs. - (Peer Reviewed Journal)

Bauchart-Thevret, C., Stoll, B., Chako, S., Burrin, D.G. 2009. Sulfur amino acid deficiency upregulates intestinal methionine cycle activity and suppresses epithelial growth in neonatal pigs. American Journal of Physiology - Endocrinology and Metabolism. 296:E1239-E1250.

A mouse chromosome 4 balancer ENU-mutagenesis screen isolates eleven lethal lines - (Peer Reviewed Journal)

Boles, M.K., Wilkinson, B.M., Maxwell, A., Lai, L., Mills, A.A., Nishijima, I., Salinger, A.P., Moskowitz, I., Hirschi, K.K., Liu, B., Bradley, A., Justice, M.J. 2009. A mouse chromosome 4 balancer ENU-mutagenesis screen isolates eleven lethal lines. Biomed Central (BMC) Genetics. 10:12.

Acute effects of enteral leucine supplementation of a low protein diet on muscle protein synthesis in neonatal pigs     - (Abstract Only)

Torrazza, R.M., Suryawan, A., Orellana, R., Gazzaneo, C., Nguyen, H., Almonaci, R., Davis, T. 2009. Acute effects of enteral leucine supplementation of a low protein diet on muscle protein synthesis in neonatal pigs [abstract]. Federation of American Societies for Experimental Biology Conference: Today's Research: Tomorrow's Health. Session: Piglet model of perinatal growth, nutrition and digestive physiology, April 18-22, 2009, New Orleans, Louisiana. Electronic Abstract: 23(1) Abstract No. 33.1.

Insulin accelerates global and mitochondrial protein synthesis rates in neonatal muscle during sepsis     - (Abstract Only)

Orellana, R.A., Gazzaneo, M.C., Wilson, F.A., Nguyen, H.V., Suryawan, A., Almonaci, R., Davis, T.A. 2009. Insulin accelerates global and mitochondrial protein synthesis rates in neonatal muscle during sepsis [abstract]. Federation of American Societies for Experimental Biology Conference: Today's Research: Tomorrow's Health. Session: Piglet model of perinatal growth, nutrition and digestive physiology, April 18-22, 2009, New Orleans, Louisiana. Electronic Abstract: 23(1) Abstract No. 33.2.

The abundance and activation of mTORC1 regulators in skeletal muscle of neonatal pigs are modulated by insulin, amino acids, and age     - (Abstract Only)

Suryawan, A., Orellana, R., Nguyen, H., Davis, T. 2009. The abundance and activation of mTORC1 regulators in skeletal muscle of neonatal pigs are modulated by insulin, amino acids, and age [abstract]. Federation of American Societies for Experimental Biology Conference: Today's Research: Tomorrow's Health. Session: Nutrient-sensing mechanisms. April 18-22, 2009, New Orleans, Louisiana. Electronic Abstract: 23(1) Abstract No. 228.3.

Long-term leucine induced stimulation of muscle protein synthesis is amino acid dependent     - (Abstract Only)

Wilson, F.A., Suryawan, A., Gazzaneo, M.C., Orellana, R.A., Nguyen, H.V., Davis, T.A. 2009. Long-term leucine induced stimulation of muscle protein synthesis is amino acid dependent [abstract]. Federation of American Societies for Experimental Biology Conference: Today's Research: Tomorrow's Health. Session: Nutrient-sensing mechanisms, April 18-22, 2009, New Orleans, Louisiana. Electronic Abstract: 23(1) Abstract No. 228.7.

Long-chain n-3 fatty acids - New anabolic compounds improving protein metabolism     - (Abstract Only)

Thivierge, M.C., Lévesque, J., Julien, P., Couture, Y., Davis, T.A. 2009. Long-chain n-3 fatty acids - New anabolic compounds improving protein metabolism [abstract]. Federation of American Societies for Experimental Biology Conference: Today's Research: Tomorrow's Health. April 18-22, 2009, New Orleans, Louisiana. Electronic Abstract: 23(1) Abstract No. LB107.

Gastric bolus feeding rapidly stimulates hepatic protein synthesis in neonatal pigs     - (Abstract Only)

Gazzaneo, M.C., Suryawan, A., Wilson, F.A., Orellana, R.A., Kimball, S.R., Nguyen, H.V., Davis, T.A. 2009. Gastric bolus feeding rapidly stimulates hepatic protein synthesis in neonatal pigs [abstract]. Federation of American Societies for Experimental Biology Conference: Today's Research: Tomorrow's Health. Session: Nutrient-sensing mechanisms, April 18-22, 2009, New Orleans, Louisiana. Electronic Abstract: 23(1) Abstract No. 228.6.

Feeding-induced time course of changes in protein synthesis in neonatal pig skeletal muscle     - (Abstract Only)

Wilson, F.A., Suryawan, A., Orellana, R.A., Kimball, S.R., Gazzaneo, M.C., Nguyen, H.V., Davis, T.A. 2009. Feeding-induced time course of changes in protein synthesis in neonatal pig skeletal muscle [abstract]. Federation of American Societies for Experimental Biology Conference. Today's Research: Tomorrow's Health. Session: Protein and amino acid metabolism I, April 18-22, 2009, New Orleans, Louisiana. Electronic Abstract 23(1), Abstract No. 738.2.

Signaling hierarchy regulating human endothelial cell development - (Peer Reviewed Journal)

Kelly, M.A., Hirschi, K.K. 2009. Signaling hierarchy regulating human endothelial cell development. Arteriosclerosis Thrombosis and Vascular Biology. 29(5):718-724.

Commentary on domestic animals in agricultural and biomedical research: An endangered enterprise - (Review Article)

Reynolds, L.P., Ireland, J.J., Caton, J.S., Bauman, D.E., Davis, T.A. 2009. Commentary on domestic animals in agricultural and biomedical research: An endangered enterprise. Journal of Nutrition. 139(3):427-428.

Arginine metabolism and nutrition in growth, health and disease     - (Peer Reviewed Journal)

Wu, G., Bazer, F.W., Davis, T.A., Kim S.W., Li, P., Rhoads, J.M., Satterfield, M.C., Smith, S.B., Spencer, T.E., Yin, Y. 2009. Arginine metabolism and nutrition in growth, health and disease. Amino Acids. 37(1):153-168.

Amino acids and insulin in neonatal growth - (Abstract Only)

Davis, T.A., Suryawan, A., Orellana, R.A. 2008. Amino acids and insulin in neonatal growth [abstract]. The 6th International Congress on Farm Animal Endocrinology, Session: Growth and Metabolic Endocrinology, November 14-16, 2008, Roanoke, Virginia. p. 33.

Regulation of muscle growth in neonates     - (Review Article)

Davis, T.A., Fiorotto, M.L. 2009. Regulation of muscle growth in neonates. Current Opinion in Clinical Nutrition and Metabolic Care. 12(1):78-85.

Positive net movements of amino acids in the hindlimb after overnight food deprivation contribute to sustaining the elevated anabolism of neonatal pigs     - (Peer Reviewed Journal)

Thivierge, M.C., Bush, J.A., Suryawan, A., Nguyen, H.V., Orellana, R.A., Burrin, D.G., Jahoor, F., Davis, T.A. 2008. Positive net movements of amino acids in the hindlimb after overnight food deprivation contribute to sustaining the elevated anabolism of neonatal pigs. Journal of Applied Physiology. 105(6):1959-1966.

Metabolic fate and function of dietary glutamate in the gut     - (Review Article)

Burrin, D.G., Stoll, B. 2009. Metabolic fate and function of dietary glutamate in the gut. American Journal of Clinical Nutrition. 90(suppl):1S-7S.

Prolonged stimulation of muscle protein synthesis by leucine in neonates is dependent on amino acid availability     - (Abstract Only)

Davis, T.A., Wilson, F.A., Suryawan, A., Gazzaneo, M.C., Orellana, R.A. 2008. Prolonged stimulation of muscle protein synthesis by leucine in neonates is dependent on amino acid availability [abstract]. The Biochemical Society Meeting, "mTOR Signalling, Nutrients and Disease", September 15-16, 2008, University of Oxford, United Kingdom. Abstract No. P015.

Enteral feeding induces diet-dependent mucosal dysfunction, bacterial overgrowth and necrotizing enterocolitis in preterm parenterally-fed pigs - (Peer Reviewed Journal)

Bjornvad, C.R., Thymann, T., Deutz, N.E., Burrin, D.G., Jensen, S.K., Jensen, B.B., Molbak, L., Boye, M., Larsson, L., Schmidt, M., Sangild, P.T. 2008. Enteral feeding induces diet-dependent mucosal dysfunction, bacterial overgrowth and necrotizing enterocolitis in preterm parenterally-fed pigs. American Journal of Physiology Gastrointestinal Liver Physiology. 295:1092-1103.

Comparative Aspects of Tissue Glutamine and Proline Metabolism - (Review Article)

Bertolo, R.F., Burrin, D.G. 2008. Comparative aspects of tissue glutamine and proline metabolism. Journal of Nutrition. 138:2032S-2039S.

Animal models to study neonatal nutrition in humans     - (Review Article)

Puiman, P., Stoll, B. 2008. Animal models to study neonatal nutrition in humans. Current Opinion in Clinical Nutrition and Metabolic Care. 11:601-606.

Leucine stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing mTORC1 activation     - (Peer Reviewed Journal)

Suryawan, A., Jeyapalan, A.S., Orellana, R.A., Wilson, F.A., Nguyen, H.V., Davis, T.A. 2008. Leucine stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing mTORC1 activation. American Journal of Physiology: Endocrinology and Metabolism. 295(4):E868-E875.

Fed levels of amino acids are required for the somatotropin-induced increase in muscle protein synthesis     - (Peer Reviewed Journal)

Wilson, F.A., Suryawan, A., Orellana, R.A., Nguyen, H.V., Jeyapalan, A.S., Gazzaneo, M.C., Davis, T.A. 2008. Fed levels of amino acids are required for the somatotropin-induced increase in muscle protein synthesis. American Journal of Physiology: Endocrinology and Metabolism. 295(4):E876-E883.

Cell signaling directing the formation and function of hemogenic endothelium during murine embryogenesis - (Peer Reviewed Journal)

Goldie, L.C., Lucitti, J.L., Dickinson, M.E., Hirschi, K.K. 2008. Cell signaling directing the formation and function of hemogenic endothelium during murine embryogenesis. Blood. 112(8):3194-3204.

Assessing identity, phenotype, and fate of endothelial progenitor cells - (Review Article)

Hirschi, K.K., Ingram, D.A., Yoder, M.C. 2008. Assessing identity, phenotype, and fate of endothelial progenitor cells. Arteriosclerosis Thrombosis and Vascular Biology. 28(9):1584-1595.

Differential regulation of protein synthesis by amino acids and insulin in peripheral and visceral tissues of neonatal pigs     - (Peer Reviewed Journal)

Suryawan, A., O'Connor, P.M.J., Bush, J.A., Nguyen, H.V., Davis, T.A. 2009. Differential regulation of protein synthesis by amino acids and insulin in peripheral and visceral tissues of neonatal pigs. Amino Acids. 37(1):97-104.

Carbohydrate and dietary fiber - (Book / Chapter)

Abrams, S.H., Shulman, R.J. 2009. Carbohydrate and dietary fiber. In: Kleinman, R.E., editor. Pediatric Nutrition Handbook. 6th edition. Elk Grove Village, IL: American Academy of Pediatrics. p. 343-356.

Nutritional regulation of mTOR signaling in skeletal muscle of neonates in vivo - (Abstract Only)

Davis, T.A., Fiorotto, M.L. 2008. Nutritional regulation of mTOR signaling in skeletal muscle of neonates in vivo [abstract]. The Federation of American Societies for Experimental Biology Summer Research Conferences, "Molecular Mechanisms Involved in the Nutrient Control of Cellular Function", Session 4, "Nutrient Control of Signal Transduction Pathways", July 20-25, 2008, Carefree, Arizona. p. 20.

Enhanced skeletal muscle protein synthesis rates in pigs treated with somatotropin requires fed amino acids levels     - (Abstract Only)

Wilson, F.A., Suryawan, A., Orellana, R.A., Nguyen, H.V., Jeyapalan, A.S., Gazzaneo, M.C., Davis, T.A. 2008. Enhanced skeletal muscle protein synthesis rates in pigs treated with somatotropin requires fed amino acids levels [abstract]. The American Dairy Science Association and the American Society of Animal Science Joint Annual Meeting, July 7-11, 2008, Indianapolis, Indiana. Journal of Animal Science, 86(E-Suppl. 2) and the Journal of Dairy Science, 91(E-Suppl. 1), Session: Growth and Development: Historical Perspective and Future Direction. p. 312.

Insulin signaling in skeletal muscle and liver of neonatal pigs during endotoxemia     - (Peer Reviewed Journal)

Orellana, R.A., Suryawan, A., Kimball, S.R., Wu, G., Nguyen, H.V., Jefferson, L.S., Davis, T.A. 2008. Insulin signaling in skeletal muscle and liver of neonatal pigs during endotoxemia. Pediatric Research. 64(5):505-510.

Insulin and amino acids are critical regulators of neonatal muscle growth     - (Peer Reviewed Journal)

Davis, T.A. 2008. Insulin and amino acids are critical regulators of neonatal muscle growth. Nutrition Today. 43(4):143-149.

Stimulation of muscle protein synthesis by somatotropin in pigs is independent of the somatotropin-induced increase in circulating insulin     - (Peer Reviewed Journal)

Wilson, F.A., Orellana, R.A., Suryawan, A., Nguyen, H.V., Jeyapalan, A.S., Frank, J., Davis, T.A. 2008. Stimulation of muscle protein synthesis by somatotropin in pigs is independent of the somatotropin-induced increase in circulating insulin. American Journal of Physiology - Endocrinology and Metabolism. 295(1):E187-E194.

Glucagon-like peptide-2 increases small intestinal mass of calves     - (Abstract Only)

Taylor, C.C., Burrin, D.G., McLeod, K.R., Harmon, D.L. 2009. Glucagon-like peptide-2 increases small intestinal mass of calves [abstract]. Joint Meeting of the ADSA, AMSA, ASAS and PSA. Journal of Animal Science. 87:234 (E-Suppl. 2).

Clinical evidence for immunomodulatory effects of probiotic bacteria - (Review Article)

Ruemmele, F.M., Bier, D.M., Marteau, P., Rechkemmer, G., Bourdet-Sicard, R., Walker, W.A., Goulet, O. 2009. Clinical evidence for immunomodulatory effects of probiotic bacteria. Journal of Pediatric Gastroenterology and Nutrition. 48:126-141.

Increased gastrointestinal permeability and gut inflammation in children with functional abdominal pain and Irritable Bowel Syndrome - (Peer Reviewed Journal)

Shulman, R.J., Eakin, M.N., Czyzewski, D.I., Jarrett, M., Ou, C. 2008. Increased gastrointestinal permeability and gut inflammation in children with functional abdominal pain and Irritable Bowel Syndrome. Journal of Pediatrics. 153(5):646-650.

Trophic Factors and Regulation of Gastrointestinal Tract and Liver Development     - (Book / Chapter)

Burrin, D.G. 2011. Trophic Factors and Regulation of Gastrointestinal Tract and Liver Development. In: Polin, R.A., Fox, W.W., Abman, S.H., editors. "Fetal and Neonatal Physiology". 4th edition. Philadelphia, PA: Saunders Publishers. p. 1-7.

Intestinal metabolism of sulfur amino acids - (Book / Chapter)

Benight, N.M., Burrin, D.G., Stoll, B. 2009. Intestinal metabolism of sulfur amino acids. In: Masella, R., Mazza, G., editors. Glutathione and Sulfur Amino Acids in Human Health and Disease. New Jersey, NJ: Wiley & Sons, Inc. p. 47-72.

Decreased insulin sensitivity due to continuous nutrient administration in neonatal pigs - (Abstract Only)

Stoll, B., Puiman, P.J., Benight, N., Bauchart, C., Burrin, D.G. 2009. Decreased insulin sensitivity due to continuous nutrient administration in neonatal pigs [abstract]. Journal of Federation of American Societies for Experimental Biology. 23:33.3.

Pediatric functional gastrointestinal disorders - (Review Article)

McOmber, M.A., Shulman, R.J. 2008. Pediatric functional gastrointestinal disorders. Nutrition in Clinical Practice. 23(3):268-274.

Sulfur amino acids are necessary for normal intestinal mucosal growth in neonatal piglets     - (Abstract Only)

Bauchart-Thevret, C., Stoll, B., Chang, X., Cui, L., Burrin, D.G. 2008. Sulfur amino acids are necessary for normal intestinal mucosal growth in neonatal piglets [abstract]. Journal of Federation of American Societies for Experimental Biology. 22:686.2

Can abdominal NIRS detect changes in intestinal blood flow and risk of NEC in premature piglets? - (Abstract Only)

Burrin, D.G., Gay, A.N., Stoll, B., Naik-Mathuria, B., Olutoye, O.O. 2008. Can abdominal NIRS detect changes in intestinal blood flow and risk of NEC in premature piglets?. Pediatric Research. E-PAS 635819.3

Intestinal trophic effect of enteral arginine is independent of blood flow in neonatal piglets     - (Abstract Only)

Puiman, P.J., Stoll, B., Van Goudoever, J.B., Burrin, D.G. 2008. Intestinal trophic effect of enteral arginine is independent of blood flow in neonatal piglets [abstract]. Pediatric Research. E-PAS 635:140.4

Endotoxin reduces muscle protein synthesis and restrains translation initiation by decreasing eIF4G phosphorylation in neonatal and young pigs - (Abstract Only)

Orellana, R.A., Gazzaneo, C., Wilson, F., Nguyen, H.V., Suryawan, A., Davis, T.A. 2008. Endotoxin reduces muscle protein synthesis and restrains translation initiation by decreasing eIF4G phosphorylation in neonatal and young pigs [abstract]. Federation of American Societies for Experimental Biology Conference: Today's Research: Tomorrow's Health. Session: Protein and Amino Acid Metabolism, April 5-9, 2008, San Diego, California. C52, Abstract #869.13.

Somatotropin enhanced muscle protein synthesis in growing pigs is not modulated by insulin - (Abstract Only)

Wilson, F.A., Nguyen, H.V., Suryawan, A., Orellana, R.A., Jeyapalan, A.S., Davis, T.A. 2008. Somatotropin enhanced muscle protein synthesis in growing pigs is not modulated by insulin [abstract]. Federation of American Societies for Experimental Biology Conference: Today's Research: Tomorrow's Health. Session: Animal Growth, April 5-9, 2008, San Diego, California. C287, Abstract #1114.2.

Rapamycin blocks leucine-induced protein synthesis by suppressing mTORC1 activation in skeletal muscle of neonatal pigs - (Abstract Only)

Suryawan, A., Jeyapalan, A.S., Orellana, R.A., Nguyen, H.V., Wilson, F.A., Davis, T.A. 2008. Rapamycin blocks leucine-induced protein synthesis by suppressing mTORC1 activiation in skeletal muscle of neonatal pigs [abstract]. Federation of American Societies for Experimental Biology Conference. Minisymposium: Nutrient Sensing Mechanisms, April 5-9, 2008, San Diego, California. Abstract #306.5.

Determination of urinary collection timeframes to enhance measurement of gastrointestinal (GI) site specific permeability in adults and children - (Abstract Only)

McOmber, M.A., Shulman, R.J. 2008. Determination of urinary collection timeframes to enhance measurement of gastrointestinal (GI) site specific permeability in adults and children [abstract]. Gastroenterology. 134(Suppl.1):A-138.

Gastrointestinal (GI) permeability is associated with trait anxiety in children with functional abdominal pain (FAP) and Irritable Bowel Syndrome (IBS) - (Abstract Only)

Shulman, R.J., Czyzewski, D.I., Lane, M., Jarrett, M., Burr, R.L. 2008. Gastrointestinal (GI) permeability is associated with trait anxiety in children with functional abdominal pain (FAP) and Irritable Bowel Syndrome (IBS) [abstract]. Gastroenterology. 134(Suppl.1):A-188

Steroid responsive eosinophilic gastric outlet obstruction in a child - (Peer Reviewed Journal)

Kellermayer, R., Tatevian, N., Klish, W., Shulman, R.J. 2008. Steroid responsive eosinophilic gastric outlet obstruction in a child. World Journal of Gastroenterology. 14(14):2270-2271.

Emerging aspects of dietary glutamate metabolism in the developing gut     - (Review Article)

Burrin, D.G., Janeczko, M.J., Stoll, B. 2008. Emerging aspects of dietary glutamate metabolism in the developing gut. Asia Pacific Journal of Clinical Nutrition. 17(Suppl. 1):368-371.

Trophic Factors and Regulation of Gastrointestinal Tract and Liver Development     - (Book / Chapter)

Janeczko, M., Burrin, D.G. 2008. Trophic factors and regulation of gastrointestinal tract and liver development. In: Neu, J. editor. Gastroenterology and Nutrition, Neonatology Questions and Controversies. Philadelphia, PA: Elsevier. p. 121-134.

Neonatal dietary cholesterol and alleles of cholesterol 7-alpha hydroxylase affect piglet cerebrum weight, cholesterol concentration, and behavior - (Peer Reviewed Journal)

Pond, W.G., Mersmann, H.J., Su, D., McGlone, J.J., Wheeler, M.B. Smith, E.O. 2008. Neonatal dietary cholesterol and alleles of cholesterol 7-alpha hydroxylase affect piglet cerebrum weight, cholesterol concentration, and behavior. Journal of Nutrition. 138(2):282-286.

Activation by insulin and amino acids of signaling components leading to translation initiation in skeletal muscle of neonatal pigs is developmentally regulated     - (Peer Reviewed Journal)

Suryawan, A., Orellana, R.A., Nguyen, H.V., Jeyapalan, A.S., Fleming, J.R., Davis, T.A. 2007. Activation by insulin and amino acids of signaling components leading to translation initiation in skeletal muscle of neonatal pigs is developmentally regulated. American Journal of Physiology - Endocrinology and Metabolism. 293(6):E1597-E1605.

Amino acid availability and age affect the leucine stimulation of protein synthesis and eIF4F formation in muscle     - (Peer Reviewed Journal)

Escobar, J., Frank, J.W., Suryawan, A., Nguyen, H.V., Davis, T.A. 2007. Amino acid availability and age affect the leucine stimulation of protein synthesis and eIF4F formation in muscle. American Journal of Physiology-Endocrinology and Metabolism. 293(6):E1615-E1621.

Inadequate satellite cell replication compromises muscle regrowth following postnatal nutrient restriction - (Abstract Only)

Fiorotto, M.L., Lopez, R., Rosenberger, R., Davis, T.A., Gomez, A.J. Malphus, E.W. 2007. Inadequate satellite cell replication compromises muscle regrowth following postnatal nutrient restriction [abstract]. 5th International Congress on Developmental Origins of Health and Disease, November 6-10, 2007, Perth, Western Australia. 83(Suppl. 1):S58[Abstract #2E-6].

Amino acids augment muscle protein synthesis in neonatal pigs during acute endotoxemia by stimulating mTOR-dependent translation initiation - (Peer Reviewed Journal)

Orellana, R.A., Jeyapalan, A., Escobar, J., Frank, J.W., Nguyen, H.V., Suryawan, A., Davis, T.A. 2007. Amino acids augment muscle protein synthesis in neonatal pigs during acute endotoxemia by stimulating mTOR-dependent translation initiation. American Journal of Physiology-Endocrinology and Metabolism. 293(5):E1416-E1425.

Postnatal ontogeny of skeletal muscle protein synthesis in pigs     - (Peer Reviewed Journal)

Davis, T.A., Suryawan, A., Orellana, R.A., Nguyen, H.V., Fiorotto, M.L. 2008. Postnatal ontogeny of skeletal muscle protein synthesis in pigs. Journal of Animal Science. 86(14 Suppl):E13-E18.

Extensive gut metabolism limits the intestinal absorption of excessive supplemental dietary glutamate loads in infant pigs     - (Peer Reviewed Journal)

Janeczko, M.J., Stoll, B., Chang, X., Guan, X., Burrin, D.G. 2007. Extensive gut metabolism limits the intestinal absorption of excessive supplemental dietary glutamate loads in infant pigs. Journal of Nutrition. 137:2384-2390.

Injury mechanism dictates contribution of bone marrow-derived cells to murine hepatic vascular regeneration - (Peer Reviewed Journal)

Kienstra, K.A., Jackson, K.A., Hirschi, K.K. 2008. Injury mechanism dictates contribution of bone marrow-derived cells to murine hepatic vascular regeneration. Pediatric Research. 63(2):131-136.

Important roles for the arginine family of amino acids in swine nutrition and production - (Peer Reviewed Journal)

Wu, G., Bazer, F.W., Davis, T.A., Jaeger, L.A., Johnson, G.A., Kim, S.W., Knabe, D.A., Meininger, C.J., Spencer, T.E., Yin, Y-L. 2007. Important roles for the arginine family of amino acids in swine nutrition and production. Livestock Science. 112(1-2):8-22.

Murine neonatal intravascular injections: Modeling newborn disease - (Peer Reviewed Journal)

Kienstra, K.A., Freysdottir, D., Gonzales, N.M., Hirschi, K.K. 2007. Murine neonatal intravascular injections: Modeling newborn disease. Journal of the American Association for Laboratory Animal Science. 46(6):50-54.

Long-chain n-3 fatty acids enhance neonatal insulin-regulated protein metabolism in piglets by differentially altering muscle lipid composition - (Peer Reviewed Journal)

Bergeron, K., Julien, P., Davis, T.A., Myre, A., Thivierge, M.C. 2007. Long-chain n-3 fatty acids enhance neonatal insulin-regulated protein metabolism in piglets by differentially altering muscle lipid composition. Journal of Lipid Research. 48:2396-2410.

Nutrient regulation of tumor and vascular endothelial cell proliferation - (Review Article)

Enciso, J.M., Hirschi, K.K. 2007. Nutrient regulation of tumor and vascular endothelial cell proliferation. Current Cancer Drug Targets. 7(5):432-437.

Recurrent abdominal pain and irritable bowel syndrome in children - (Peer Reviewed Journal)

McOmber, M.E., Shulman, R.J. 2007. Recurrent abdominal pain and irritable bowel syndrome in children. Current Opinion in Pediatrics. 19(5):581-585.

Glucagon-like peptide-2 (GLP-2) activates the mTOR signaling through a PI3-kinase-Akt-dependent pathway - (Abstract Only)

Guan, X., Li, X., Li, D., Wang, Y., Qiao, S., Burrin, D., Chang, B., Chan, L. 2007. Glucagon-like peptide-2 (GLP-2) activates the mTOR signaling through a PI3-kinase-Akt-dependent pathway [abstract]. "ENDO 07", 89th Annual Meeting of the Endocrine Society, Juen 2-5, 2007, Toronto, Canada. Paper No. P2-595.

Maturation of oral feeding skills in preterm infants - (Peer Reviewed Journal)

Amaizu, N., Shulman, R.J., Schanler, R.J., Lau, C. 2008. Maturation of oral feeding skills in preterm infants. Acta Paediatrica. 97(1):61-67.

Aromatic Amino Acids and Related Substances: Chemistry, Biology, Medicine, and Application - (Peer Reviewed Journal)

Takai, K., Bier, D.M., Cynober, L., Morris, S.M., Shimomura, Y. 2007. Aromatic amino acids and related substances: Chemistry, biology, medicine, and application. Journal of Nutrition (Supplement). 137(6S-1):1501S-1598S.

Glucose stimulates protein synthesis in skeletal muscle of neonatal pigs through an AMPK- and mTOR-independent process - (Peer Reviewed Journal)

Jeyapalan, A.S., Orellana, R.A., Suryawan, A., O'Connor, P.M.J., Nguyen, H.V., Escobar, J., Frank, J.W., Davis, T.A. 2007. Glucose stimulates protein synthesis in skeletal muscle of neonatal pigs through an AMPK- and mTOR-independent process. American Journal of Physiology Endocrinology and Metabolism. 293(2):E595-E603.

Modulation of protein synthesis by somatotropin and insulin in skeletal muscle of growing pigs - (Abstract Only)

Wilson, F.A., Nguyen, H.V., Suryawan, A., Orellana, R.A., Fleming, J.G., Jeyapalan, A.S., Davis, T.A. 2007. Modulation of protein synthesis by somatotropin and insulin in skeletal muscle of growing pigs [abstract]. Journal of Animal Science, Proceeding of the 2007 Annual Meeting of the American Society of Animal Science, July 8-12, 2007, San Antonio, Texas. 85(Suppl. 1):M144, p. 49.

The activation of insulin and nutrient signaling components leading to translation initiation in skeletal muscle of neonatal pigs is developmentally regulated - (Abstract Only)

Suryawan, A., Orellana, R.A., Jeyapalan, A.S., Nguyen, H.V., Fleming, J.R., Davis, T.A. 2007. The activation of insulin and nutrient signaling components leading to translation initiation in skeletal muscle of neonatal pigs is developmentally regulated [abstract]. Journal of Animal Science, Proceeding of the 2007 Annual Meeting of the American Society of Animal Science, July 8-12, 2007, San Antonio, Texas. 85(Suppl 1):463, p. 391.

Postnatal ontogeny of skeletal muscle protein synthesis in pigs - (Abstract Only)

Davis, T.A., Suryawan, A., Orellana, R.A., Fiorotto, M.L. 2007. Postnatal ontogeny of skeletal muscle protein synthesis in pigs [abstract]. Journal of Animal Science, Proceeding of the 2007 Annual Meeting of the American Society of Animal Science, July 8-12, 2007, San Antonio, Texas. 85(Suppl. 1):630, p. 445.

Differential effects of leucine on translation initiation factor activation and protein synthesis in skeletal muscle, renal and adipose tissues of neonatal pigs - (Abstract Only)

Escobar, J., Nguyen, H.V., Davis, T.A. 2007. Differential effects of leucine on translation initiation factor activation and protein synthesis in skeletal muscle, renal and adipose tissues of neonatal pigs [abstract]. Journal of Animal Science, Proceeding of the 2007 Annual Meeting of the American Society of Animal Science, July 8-12, 2007, San Antonio, Texas. 85(Suppl. 1):618, p. 441.

Glucagon-like peptide-2 (GLP-2) activates the Mtor signaling through a PI3-kinase-Akt-dependent pathway - (Abstract Only)

Li, X., Li, D., Wang, Y., Qiao, S., Chang, B.H., Burrin, D., Chan, L., Guan, X. 2007. Glucagon-like peptide-2 (GLP-2) activates the Mtor signaling through a PI3-kinase-Akt-dependent pathway [abstract]. Gastroenterology. 132(4 Supplement 2):A-546.

Glucagon-like peptide-2 activates the mTOR signaling through a PI3-kinase-Akt-dependent pathway - (Abstract Only)

Li, X., Li, D., Wang, Y., Qiao, S., Chang, B.H., Burrin, D.G., Chan, L., Guan, X. 2007. Glucagon-like peptide-2 activates the mTOR signaling through a PI3-kinase-Akt-dependent pathway [abstract]. Journal of Federation of American Societies for Experimental Biology. 21(6):A1075-A1076.

C57BL/6J male offspring exposed "in utero" and during weaning to a maternal low protein diet have reduced muscle weight by 12 months of age - (Abstract Only)

Fiorotto, M.L., Rosetta, R., Yu, Z., Oliver, W., Van den Veyver, I. 2007. C57BL/6J Male offspring exposed "in utero" and during weaning to a maternal low protein diet have reduced muscle weight by 12 months of age [abstract]. Reproductive Sciences. 14(1)[Suppl]:95A.

Embryonic vasculogenesis and hematopoietic specification - (Review Article)

Goldie, L.C., Nix, M.K., Hirschi, K.K. 2008. Embryonic vasculogenesis and hematopoietic specification. Organogenesis. 4(4):257-263.

Insulin and amino acids stimulate whole body protein synthesis in neonates - (Abstract Only)

Jeyapalan, A., Orellana, R.A., Burrin, D.G., Fiorotto, M.L., Jahoor, F., Nguyen, H.V., Suryawan, A., Davis, T.A. 2007. Insulin and amino acids stimulate whole body protein synthesis in neonates [abstract]. The Federation of American Societies for Experimental Biology Journal. 21(5):A334.

Stimulation of whole body protein synthesis by insulin in neonates is dependent on the pattern of amino acids available - (Abstract Only)

Orellana, R.A., Fiorotto, M.L., Jahoor, F., Burrin, D.G., Nguyen, H.V., Suryawan, A., Davis, T.A. 2007. Stimulation of whole body protein synthesis by insulin in neonates is dependent on the pattern of amino acids available [abstract]. The Federation of American Societies for Experimental Biology Journal. 21(5):A162.

The activation of nutrient signaling components leading to mRNA translation in skeletal muscle of neonatal pigs is developmentally regulated - (Abstract Only)

Suryawan, A., Orellana, R.A., Jeyapalan, A.S., Nguyen, H.V., Fleming, J.R., Davis, T.A. 2007. The activation of nutrient signaling components leading to mRNA translation in skeletal muscle of neonatal pigs is developmentally regulated [abstract]. The Federation of American Societies for Experimental Biology Journal. 21(5):A714.

Acute IGF-I infusion stimulates whole body protein synthesis but does not reduce proteolysis in neonates - (Abstract Only)

Wilson, F., Fiorotto, M.L., Burrin, D.G., Jahoor, F., Nguyen, H.V., Suryawan, A., Davis, T.A. 2007. Acute IGF-I infusion stimulates whole body protein synthesis but does not reduce proteolysis in neonates [abstract]. The Federation of American Societies for Experimental Biology Journal. 21(6):A1119.

The activation of insulin signaling components leading to mRNA translation in skeletal muscle of neonatal pigs is developmentally regulated - (Abstract Only)

Suryawan, A., Orellana, R.A., Jeyapalan, A.S., Nguyen, H.V., Fleming, J.R., Davis, T.A. 2007. The activation of insulin signaling components leading to mRNA translation in skeletal muscle of neonatal pigs is developmentally regulated [abstract]. The Federation of American Societies for Experimental Biology Journal. 21(6):A1119.

Mechanisms of disease: update on the molecular etiology and fundamentals of parenteral nutrition associated cholestasis - (Peer Reviewed Journal)

Carter, B.A., Shulman, R.J. 2007. Mechanisms of disease: Update on the molecular etiology and fundamentals of parenteral nutrition associated cholestasis. Nature Clinical Practice Gastroenterology & Hepatology. 4(5):277-287.

EGD IN CHILDREN WITH ABDOMINAL PAIN: A SYSTEMATIC REVIEW - (Review Article)

Thakkar, K., Gilger, M.A., Shulman, R.J., El Serag, H.B. 2007. EGD in children with abdominal pain: A systematic review. American Journal of Gastroenterology. 102:654-661.

FECAL CALPROTECTIN AND GASTROINTESTINAL (GI) PERMEABILITY CORRELATE WITH DISEASE ACTIVITY INDEX, AND HISTOLOGIC, ENDOSCOPIC, AND RADIOLOGIC FINDINGS IN CHILDREN WITH CROHN DISEASE (CD) - (Abstract Only)

Shulman, R.J., Eakin, M., Tatevian, N. 2007. Fecal calprotectin and gastrointestinal (GI) permeability correlate with disease activity index, and histologic, endoscopic, and radiologic findings in children with crohn disease (CD) [abstract]. Gastroenterology. 132(Suppl.2):A649.

ABNORMAL GASTRIC AND COLONIC PERMEABILITY IN CHILDREN WITH RECURRENT ABDOMINAL PAIN (RAP) - (Abstract Only)

Shulman, R.J., Czyzewski, D., Jarrett, M.E., Zeltzer, L. 2007. Abnormal gastric and colonic permeability in children with recurrent abdominal pain (RAP) [abstract]. Gastroenterology. 132(Supl.2):A65.

Methionine transmethylation and transsulfuration in the piglet gastrointestinal tract     - (Peer Reviewed Journal)

Riedijk, M.A., Stoll, B., Chacko, S., Schierbeek, H., Sunehag, A.L., Van Goudoever, J.B., Burrin, D.G. 2007. Methionine transmethylation and transsulfuration in the piglet gastrointestinal tract. Proceedings of the National Academy of Sciences. 104(9):3408-3413.

Assaying endothelial-mural cell interactions - (Book / Chapter)

Nix, M.K., Hirschi, K.K. 2006. Assaying endothelial-mural cell interactions. In: Staton, C.A., Lewis, C., Bicknell, R., editors. Angiogenesis Assays: A Critical Appraisal of Current Techniques. West Sussex, England: John Wiley & Sons Ltd. p. 123-137.

Long-chain omega-3 fatty acids regulate bovine whole-body protein metabolism by promoting muscle insulin signalling to the Akt-mTOR-S6K1 pathway and insulin sensitivity.     - (Peer Reviewed Journal)

Gingras, A-A., White, P.J., Chouinard, P.Y., Julien, P., Davis, T.A., Dombrowski, L., Couture, Y., Dubreuil, P., Myre, A., Bergeron, K., Marette, A., Thivierge, M.C. 2007. Long-chain omega-3 fatty acids regulate bovine whole-body protein metabolism by promoting muscle insulin signalling to the Akt-mTOR-S6K1 pathway and insulin sensitivity. Journal of Physiology. 579(Pt 1):269-284.

PARENTERAL NUTRITION INDICATIONS, ADMINISTRATION, AND MONITORING - (Book / Chapter)

Shulman, R.J., Phillips, S. 2007. Parenteral nutrition indications, administration, and monitoring. In: Baker, S.S., Baker, R.D., Davis, A. M., editors. Pediatric Nutrition Support. Boston, MA, Jones and Barlett Publishers. p. 273-285.

Oral "N"-Carbamylglutamate supplementation increases protein synthesis in skeletal muscle of piglets     - (Peer Reviewed Journal)

Frank, J.W., Escobar, J., Nguyen, H.V., Jobgen, S.C., Jobgen, W.S., Davis, T.A., Wu, G. 2007. Oral "N"-Carbamylglutamate supplementation increases protein synthesis in skeletal muscle of piglets. Journal of Nutrition. 137(2):315-319.

Emerging aspects of gut sulfur amino acid metabolism - (Review Article)

Burrin, D.G., Stoll, B. 2007. Emerging aspects of gut sulfur amino acid metabolism. Current Opinion in Clinical Nutrition and Metabolic Care. 10:63-68.

RECURRENT ABDOMINALPAIN IN PRIMARY AND TERTIARY CARE: DIFFERENCES AND SIMILARITIES - (Peer Reviewed Journal)

Czyzewski, D.I., Eakin, M.N., Lane, M.M., Jarrett, M., Shulman, R.J. 2007. Recurrent abdominal pain in primary and tertiary care: differences and similarities. Children's Health Care. 36(2):137-153.

Insulin stimulates muscle protein synthesis in neonates during endotoxemia despite repression of translation initiation - (Peer Reviewed Journal)

Orellana, R.A., Kimball, S.R., Suryawan, A., Escobar, J., Nguyen, H.V., Jefferson, L.S., Davis, T.A. 2007. Insulin stimulates muscle protein synthesis in neonates during endotoxemia despite repression of translation initiation. American Journal of Physiology Endocrinology and Metabolism. 292(2):E629-E636.

FEEDING AN ELEMENTAL DIET VS A MILK-BASED FORMULA DOES NOT DECREASE INTESTINAL MUCOSAL GROWTH IN INFANT PIGS. - (Peer Reviewed Journal)

Stoll, B., Price, P.T., Reeds, P.J., Chang, X., Henry, J.F., Van Goudoever, J.B., Holst, J.J., Burrin, D.G. 2006. Feeding an elemental diet vs a milk-based formula does not decrease intestinal mucosal growth in infant pigs. Journal of Parenteral and Enteral Nutrition. 30(1):32-39.

Utility of fecal calprotectin in differentiating inflammatory bowel disease (IBD) from recurrent abdominal pain (RAP) in children - (Abstract Only)

Shulman, R.J. 2006. Utility of fecal calprotectin in differentiating inflammatory bowel disease (IBD) from recurrent abdominal pain (RAP) in children [abstract]. Gastroenterology. 130(4):A206-A207.

Characteristics of pain and stooling in children with recurrent abdominal pain - (Peer Reviewed Journal)

Shulman, R.J., Eakin, M.N., Jarrett, M., Czyzewski, D.I., Zelter, L.K. 2007. Characteristics of pain and stooling in children with recurrent abdominal pain. Journal of Pediatric Gastroenterology and Nutrition. 44(2):203-208.

Gastrointestinal (GI) inflamation in children with recurrent abdominal pain (RAP) is not related to pain and stooling pattern - (Abstract Only)

Shulman, R.J., Czyzewski, D., Jarrett, M., Zeltzer, L. 2006. Gastrointestinal (GI) inflamation in children with recurrent abdominal pain (RAP) is not related to pain and stooling pattern [abstract]. Gastroenterology. 130(4):A190.

Total parenteral nutrition induces liver steatosis and apoptosis in neonatal piglets     - (Peer Reviewed Journal)

Wang, H., Khaoustov, V.I., Krishnan, B., Cai, W., Stoll, B., Burrin, D.G., Yoffe, B. 2006. Total parenteral nutrition induces liver steatosis and apoptosis in neonatal piglets. Journal of Nutrition. 136:2547-2552.

GLP-2 rapidly activates divergent intracellular signaling pathways involved in intestinal cell survival and proliferation in neonatal piglets     - (Peer Reviewed Journal)

Burrin, D.G., Stoll, B., Guan, X., Cui, L., Chang, X., Hadsell, D. 2007. GLP-2 rapidly activates divergent intracellular signaling pathways involved in intestinal cell survival and proliferation in neonatal piglets. American Journal of Physiology - Endocrinology and Metabolism. 292:E281-E291

First-pass metabolism limits the intestinal absorption of enteral alpha-ketoglutarate in young pigs     - (Peer Reviewed Journal)

Lambert, B.D., Filip, R., Stoll, B., Junghans, P., Derno, M., Hennig, U., Souffrant, W.B., Pierzynowski, S., Burrin, D.G. 2006. First-pass metabolism limits the intestinal absorption of enteral alpha-ketoglutarate in young pigs. Journal of Nutrition. 136:2779-2784.

Factors regulating gastric emptying in preterm infants - (Peer Reviewed Journal)

Ramirez, A., Wong, W.W., Shulman, R.J. 2006. Factors regulating gastric emptying in preterm infants. Journal of Pediatrics. 149(4):475-479.

What is the role of the vasculature in the neural stem cell niche? - (Review Article)

Falender, A.E., Hirschi, K.K. 2006. What is the role of the vasculature in the neural stem cell niche? Regenerative Medicine. 1(4):481-484.

Development and enteral long-chain n-3 fatty acids differentially alters muscle intracellular pools of free amino acids in the neonate piglet - (Abstract Only)

Thivierge, M.C., Bergeron, K., Julien, P., Davis, T.A. 2006. Development and enteral long-chain n-3 fatty acids differentially alters muscle intracellular pools of free amino acids in the neonate piglet [abstract]. Journal of Animal Science. 84(Suppl 1):144.

Skeletal muscle protein synthesis in neonatal pigs is stimulated by A-ketoisocaproic acid, but not by norleucine - (Abstract Only)

Escobar, J., Frank, J.W., Suryawan, A., Nguyen, H.V., Davis, T.A. 2006. Skeletal muscle protein synthesis in neonatal pigs is stimulated by A-ketoisocaproic acid, but not by norleucine [abstract]. Journal of Animal Science. 84(Suppl 1):258.

Stimulation of muscle protein synthesis by leucine is dependent on plasma amino acid availability - (Abstract Only)

Escobar, J., Frank, J.W., Suryawan, A., Nguyen, H.V., Davis, T.A. 2006. Stimulation of muscle protein synthesis by leucine is dependent on plasma amino acid availability [abstract]. Journal of Animal Science. 84(Suppl 1):284.

ENERGY IMBALANCE UNDERLYING THE DEVELOPMENT OF CHILDHOOD OBESITY IN HISPANIC CHILDREN - (Abstract Only)

Butte, N., Christiansen, E., Sorensen, T. 2006. Energy imbalance underlying the development of childhood obesity in Hispanic children [abstract]. Obesity. 14:A68.

Developmental regulation of the activation of signaling components leading to translation initiation in skeletal muscle of neonatal pigs - (Peer Reviewed Journal)

Suryawan, A., Escobar, J., Frank, J.W., Nguyen, H.V., Davis, T.A. 2006. Developmental regulation of the activation of signaling components leading to translation initiation in skeletal muscle of neonatal pigs. American Journal of Physiology, Endocrinology and Metabolism. 291(4):E849-E859.

Transplacental transfer of a growth hormone-releasing hormone peptide from mother to fetus in the rat. - (Peer Reviewed Journal)

Fiorotto, M.L., Lopez, R., Oliver, W.T., Khan, A.S., Draghia-Akli, R. 2006. Transplacental transfer of a growth hormone-releasing hormone peptide from mother to fetus in the rat. DNA and Cell Biology. 25(8):429-437.

LOCAL IGF-I ENHANCES THE SENSITIVITY OF MUSCLE PROTEIN SYNTHESIS TO INSULIN - (Abstract Only)

Oliver, W.T., Rosenberger, J., Lopez, R., Fiorotto, M.L. 2006. The local IGF-I enhances the sensitivity of muscle protein synthesis to insulin [abstract]. The 88th Annual Meeting of The Endocrine Society, June 24-27, 2006, Boston, Massachusetts. Abstract #OR40-6, p. 134.

DIET- AND COLONIZATION-DEPENDENT INTESTINAL DYSFUNCTION PREDISPOSES TO NECROTIZING ENTEROCOLITIS IN PRETERM PIGS - (Peer Reviewed Journal)

Sangild, P.T., Siggers, R.H., Schmidt, M., Elnif, J., Bjornvad, C.R., Thymann, T., Grondahl, M.L., Hansen, A.K., Jensen, S.K., Boye, M., Moelbak, L., Buddington, R.K., Westrom, B.R., Holst, J.J., Burrin, D.G. 2006. Diet- and colonization-dependent intestinal dysfunction predisposes to necrotizing enterocolitis in preterm pigs. Gastroenterology. 130(6):1776-1792.

HEART RATE VARIABILITY AND 24-HOUR MINIMUM HEART RATE - (Peer Reviewed Journal)

Burr, R.L., Motzer, S.A., Chen, W., Cowan, M.J., Shulman, R.J., Heitkemper, M.M. 2006. Heart rate variability and 24-hour minimum heart rate. Biological Research for Nursing. 7(4):256-267.

Gut glutamate metabolism is extensive in piglets supplemented with dietary glutamate     - (Abstract Only)

Janeczko, M.J., Stoll, B., Burrin, D.G. 2006. Gut glutamate metabolism is extensive in piglets supplemented with dietary glutamate [abstract]. Pediatric Academic Societies Annual Meeting. 59: Abstract No.4136.6. Available: http://www.abstracts2view.com/pasall/view.php?nu=PAS6L1_1973.

Chronic parenteral nutrition reduces lean tissue growth and induces insulin resistance in neonatal piglets     - (Abstract Only)

Horst, D.A., Sedenquist, M., Stoll, B., Ellis, K., Burrin, D. 2006. Chronic parenteral nutrition reduces lean tissue growth and induces insulin resistance in neonatal piglets [abstract]. Pediatric Academic Societies Annual Meeting. 59:Abstract No.4136.7. Available: http://www.abstracts2view.com/pasall/view.php?nu=PAS6L1_3024.

Multicenter, randomized, double-blind study comparing 20 and 40 mg of pantoprazole for symptom relief in adolescents (12 to 16 years of age) with gastroesophageal reflux disease (GERD) - (Peer Reviewed Journal)

Tsou, M.V., Baker, R., Book, L., Hammo, A., Soffer, E.F., Wang, W., Comer, G.M., Members of the 326 Study Group. 2006. Multicenter, randomized, double-blind study comparing 20 and 40 mg of pantoprazole for symptom relief in adolescents (12 to 16 years of age) with Gastroesophageal Reflux Disease (GERD). Clinical Pediatrics. 45(8):741-749.

STIMULATION OF MUSCLE PROTEIN SYNTHESIS BY GLUCOSE IN NEONATES IS AMP KINASE INDEPENDENT - (Abstract Only)

Jeyapalan, A.S. Orellana, R.A., Suryawan, A., Nguyen, H.V., Escobar, J., Frank, J., Davis, T.A. 2006. Stimulation of muscle protein synthesis by glucose in neonates is AMP kinase independent [abstract]. The Federation of American Societies for Experimental Biology Conference: Advancing the Biomedical Frontier, April 1-5, 2006, San Francisco, California. 20(5):Part II, p. A1046.

REGULATION OF ERK EXPRESSION BY MUSCLE IGF-I "IN VIVO" DETERMINES THE CAPACITY FOR MYONUCLEAR PROLIFERATION - (Abstract Only)

Oliver, W.T., Lopez, R., Yorks, K.A., Fiorotto, M.L. 2006. Regulation of ERK expression by muscle IGF-I "in vivo" determines the capacity for myonuclear proliferation [abstract]. The Federation of American Societies for Experimental Biology Conference: Advancing the Biomedical Frontier, April 1-5, 2006, San Francisco, California. 20(5):Part II, p. A1046.

MATERNAL DIETARY METHYL DONOR SUPPLEMENTATION OF "AXIN(FU)/+" MICE PREVENTS TAIL KINKS BY TAIL-SPECIFIC CPG HYPERMETHYLATION AT "AXIN(FU)" - (Abstract Only)

Waterland, R.A., Lin, J-R., Smith, C.A., Tahiliani, K. 2006. Maternal dietary methyl donor supplementation of "Axin(Fu)/+" mice prevents tail kinks by tail-specific CpG hypermethylation at "Axin(Fu)" [abstract]. The Federation of American Societies for Experimental Biology Conference: Advancing the Biomedical Frontier, April 1-5, 2006, San Francisco, California. 20(5):Part II, p. A1339.

AMINO ACIDS AUGMENT MUSCLE PROTEIN SYNTHESIS IN NEONATAL PIGS DURING ENDOTOXEMIA BY MODULATING TRANSLATION INITIATION - (Abstract Only)

Orellana, R.A., Escobar, J., Jeyapalan, A.S., Nguyen, H.V., Suryawan, A., Frank, J., Davis, T.A. 2006. Amino acids augment muscle protein synthesis in neonatal pigs during endotoxemia by modulating translation initiation [abstract]. The Federation of American Societies for Experimental Biology Conference: Advancing the Biomedical Frontier, April 1-5, 2006, San Francisco, California. 20(4):Part I, p. A9.

ORAL N-CARBAMYLGLUTAMATE (NCG) SUPPLEMENTATION INCREASES GROWTH RATE IN SOW-REARED PIGLETS - (Abstract Only)

Frank, J.W., Escobar, J., Nguyen, H.V., Jobgen, S.C., Davis, T.A., Wu, G. 2006. Oral N-carbamylglutamate (NCG) supplementation increases growth rate in sow-reared piglets [abstract]. The Federation of American Societies for Experimental Biology Conference: Advancing the Biomedical Frontier, April 1-5, 2006, San Francisco, California. 20(4):Part I, p. A425.

DEVELOPMENTAL REGULATION OF THE ACTIVATION OF SIGNALING COMPONENTS LEADING TO TRANSLATION INITIATION IN SKELETAL MUSCLE OF NEONATAL PIGS - (Abstract Only)

Suryawan, A., Escobar, J., Frank, J.W., Nguyen, H.V., Liu, C.W., Davis, T.A. 2006. Developmental regulation of the activation of signaling components leading to translation initiation in skeletal muscle of neonatal pigs [abstract]. The Federation of American Societies for Experimental Biology Conference: Advancing the Biomedical Frontier, April 1-5, 2006, San Francisco, California. 20(4):Part I, p. A425.

LEUCINE STIMULATION OF SKELETAL MUSCLE PROTEIN SYNTHESIS DURING PROLONGED LEUCINE INFUSION IS DEPENDENT ON AMINO ACID AVAILABILITY - (Abstract Only)

Escobar, J., Frank, J.W., Suryawan, A., Nguyen, H.V., Davis, T.A. 2006. Leucine stimulation of skeletal muscle protein synthesis during prolonged leucine infusion is dependent on amino acid availability [abstract]. The Federation of American Societies for Experimental Biology Conference: Advancing the Biomedical Frontier, April 1-5, 2006, San Francisco, California. 20(4):Part I, p. A162.

EFFECT OF THE LEUCINE ANALOGS, ALPHA-KETOISOCAPROIC ACID (KIC) AND NORLEUCINE, ON MUSCLE PROTEIN SYNTHESIS AND TRANSLATION INITIATION FACTOR ACTIVATION IN NEONATAL PIGS - (Abstract Only)

Escobar, J., Frank, J.W., Suryawan, A., Nguyen, H.V., Davis, T.A. 2006. Effect of the leucine analogs, Alpha-ketoisocaproic acid (KIC)and norleucine, on muscle protein synthesis and translation initiation factor activation in neonatal pigs [abstract]. The Federation of American Societies for Experimental Biology Conference: Advancing the Biomedical Frontier, April 1-5, 2006, San Francisco, California. 20(4):Part I, p. A162.

MEASURING SPLANCHNIC AMINO ACID METABOLISM IN VIVO USING STABLE ISOTOPIC TRACERS - (Review Article)

Stoll, B., Burrin, D.G. 2006. Measuring splanchnic amino acid metabolism in vivo using stable isotopic tracers. Journal of Animal Science. 84 (Supplement):E60-E72.

Kinetics of splanchnic 13C-cysteine metabolism in infant pigs     - (Abstract Only)

Cottrell, J., Stoll, B., Burrin, D. 2006. Kinetics of splanchnic 13C-cysteine metabolism in infant pigs [abstract]. Journal of Federation of American Societies for Experimental Biology. 20(4):A9.

Glucagon-like peptide-2 intracellularly stimulates eNOS phosphorylation and specifically induces submucosal arteriole vasodilation via a sheer stress-independent, local neural mechanism - (Abstract Only)

Guan, X., Zhang, K., Karpen, H., Bukowski, J., Bian, X., Galligan, J., Burrin, D. 2006. Glucagon-like peptide-2 intracellularly stimulates eNOS phosphorylation and specifically induces submucosal arteriole vasodilation via a sheer strees-independent, local neural mechanism [abstract]. Gastroenterology. 130:A686.

MODULATION OF MUSCLE PROTEIN SYNTHESIS BY INSULIN IS MAINTAINED DURING NEONATAL ENDOTOXEMIA - (Peer Reviewed Journal)

Orellana, R.A., O'Connor, P.M.J., Bush, J.A., Suryawan, A., Thivierge, M.C. Nguyen, H.V., Fiorotto, M.L., Davis, T.A. 2006. Modulation of muscle protein synthesis by insulin is maintained during neonatal endotoxemia. American Journal Physiology - Endocrinology and Metabolism. 291(1):E159-E166.

Intestinal amino acid metabolism in neonates     - (Proceedings)

Van Goudoever, J.B., Van Der Schoor, S.R., Stoll, B., Burrin, D.G., Wattimena, D., Schierbeek, H., Schaart, M.W., Riedijk, M.A., Van Der Lugt, J. 2006. Intestinal amino acid metabolism in neonates. In: Rigo, J., Ziegler, E.E., editors. Nestle Nutrition Workshop Series Pediatric Program. November 20-24, 2005, Ho Chi Minh City, Viet Nam. S. Karger AG, Basel (Switzerland). 58:95-108.

FORMULA-FEEDING REDUCES LACTOSE DIGESTIVE CAPACITY IN NEONATAL PIGS. - (Peer Reviewed Journal)

Thymann, T., Burrin, D.G., Tappenden, K.A., Bjornvad, C.R., Jensen, S.K., Sangild, P.T. 2006. Formula-feeding reduces lactose digestive capacity in neonatal pigs. British Journal of Nutrition. 95:1075-1081.

GLP-2 RECEPTOR LOCALIZES TO ENTERIC NEURONS AND ENDOCRINE CELLS EXPRESSING VASOACTIVE PEPTIDES AND MEDIATES INCREASED BLOOD FLOW. - (Peer Reviewed Journal)

Guan, X., Karpen, H.E., Bukowski, J.T., Stephens, J., Niu, S., Zhang, G., Stoll, B., Finegold, M.J., Holst, J.J., Burrin, D.G. 2006. GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow. Gastroenterology. 130:150-164.

GLUCAGON-LIKE PEPTIDE-2 PROTECTS AGAINST TPN-INDUCED INTESTINAL HEXOSE MALABSORPTION IN ENTERALLY RE-FED PIGLETS. - (Peer Reviewed Journal)

Cottrell, J.J., Stoll, B., Buddington, R.K., Stephens, J.E., Cui, L., Chang, X., Burrin, D.G. 2005. Glucagon-like peptide-2 protects against TPN-induced intestinal hexose malabsorption in enterally re-fed piglets. American Journal of Physiology - Gastrointestinal and Liver Physiology. 53:G293-G300.

GLUCAGON-LIKE PEPTIDE-2 ACUTELY INCREASES PROXIMAL SMALL INTESTINAL BLOOD FLOW IN TPN-FED NEONATAL PIGLETS. - (Peer Reviewed Journal)

Stephens, J., Stoll, B., Cottrell, J., Chang, X., Helmrath, M., Burrin, D.G. 2006. Glucagon-like peptide-2 acutely increases proximal small intestinal blood flow in TPN-fed neonatal piglets. American Journal of Physiology - Regulatory Integrative & Comparative Physiology. 59:R283-R289.

REGULATION OF CARDIAC AND SKELETAL MUSCLE PROTEIN SYNTHESIS BY INDIVIDUAL BRANCHED-CHAIN AMINO ACIDS IN NEONATAL PIGS - (Peer Reviewed Journal)

Escobar, J., Frank, J.W., Suryawan, A., Nguyen, H.V., Kimball, S.R., Jefferson, L.S., Davis, T.A. 2006. Regulation of cardiac and skeletal muscle protein synthesis by individual branched-chain amino acids in neonatal pigs. American Journal Physiology-Endocrinology and Metabolism. 290(4):E612-E621.

MITOMYCIN C IN THE MANAGEMENT OF PEDIATRIC CAUSTIC ESOPHAGEAL STRICTURES. A CASE REPORT - (Peer Reviewed Journal)

Olutoye, O.O., Shulman, R.J., Cotton, R.T. 2006. Mitomycin C in the management of pediatric caustic esophageal strictures. A case report. Journal of Pediatric Surgery. 41:E1-E3.

EXPRESSION OF THE TGF-BETA FAMILY OF LIGANDS IS DEVELOPMENTALLY REGULATED IN SKELETAL MUSCLE OF NEONATAL RATS - (Peer Reviewed Journal)

Suryawan, A., Frank, J.W., Nguyen, H.V., Davis, T.A. 2006. Expression of the TGF-Beta family of ligands is developmentally regulated in skeletal muscle of neonatal rats. Pediatric Research. 59(2):175-179.

THE LOCAL EXPRESSION AND ABUNDANCE OF INSULIN-LIKE GROWTH FACTOR (IGF) BINDING PROTEINS IN SKELETAL MUSCLE ARE REGULATED BY AGE AND GENDER BUT NOT LOCAL IGF-I "IN VIVO" - (Peer Reviewed Journal)

Oliver, W.T., Rosenberger, J., Lopez, R., Gomez, A., Cummings, K.K. Fiorotto, M.L. 2005. The local expression and abundance of insulin-like growth factor (IGF) binding proteins in skeletal muscle are regulated by age and gender but not local IGF-I "in vivo". Endocrinology. 146(12):5455-5462.

DIETARY PROTEIN AND LACTOSE INCREASE TRANSLATION INITIATION FACTOR ACTIVATION AND TISSUE PROTEIN SYNTHESIS IN NEONATAL PIGS - (Peer Reviewed Journal)

Frank, J.W., Escobar, J., Suryawan, A., Nguyen, H.V., Kimball, S.R., Jefferson, L.S., Davis, T.A. 2006. Dietary protein and lactose increase translation initiation factor activation and tissue protein synthesis in neonatal pigs. American Journal Physiology - Endocrinology and Metabolism. 290(2):E225-E233.

UNEXPLAINED VISCERAL PAIN IN CHILDREN: PATHOPHYSIOLOGY, CLINICAL FEATURES AND MANAGEMENT - (Book / Chapter)

(25-Jul-05)

EFFECT OF LACTOBACILLUS GG ON INTESTINAL INTEGRITY IN MALAWIAN CHILDREN AT RISK OF TROPICAL ENTEROPATHY - (Peer Reviewed Journal)

Galpin, L., Manary, M.J., Fleming, K., Ou, C., Ashorn, P., Shulman, R.J. 2005. Effect of Lactobacillus GG on intestinal integrity in Malawian children at risk of tropical enteropathy. American Journal of Clinical Nutrition. 82(11):1040-1045.

Effect of Lactobacillus GG on intestinal integrity in Malawian children at risk of tropical enteropathy - (Peer Reviewed Journal)

Galpin, L., Manary, M.J., Fleming, K., Ou, C.N., Ashorn, P., Shulman, R.J. 2005. Effect of Lactobacillus GG on intestinal integrity in Malawian children at risk of tropical enteropathy. American Journal of Clinical Nutrition. 82(11):1040-1045.

NUTRITIONAL AND FUNCTIONAL IMPORTANCE OF INTESTINAL SULFUR AMINO ACID METABOLISM - (Review Article)

Shoveller, A.K., Stoll, B., Ball, R.O., Burrin, D.G. 2005. Nutritional and functional importance of intestinal sulfur amino acid metabolism. Journal of Nutrition. 135:1609-1612.

PARENTERAL NUTRITION-ASSOCIATED CHOLESTASIS IN NEONATES: MULTIVARIATE ANALYSIS OF THE POTENTIAL PROTECTIVE EFFECT OF TAURINE - (Peer Reviewed Journal)

Spencer, A.U., Yu, S., Tracy, T.F., Aouthamany, M.M., Llanos, A., Brown, M.B., Brown, M., Shulman, R.J., Hirschl, R.B., Derusso, P.A., Cox, J., Dahlgren, J., Strouse, P.J., Groner, J.I., Teitelbaum, D.H. 2005. Parenteral nutrition-associated cholestasis in neonates: multivariate analysis of the potential protective effect of taurine. Journal of Parenteral and Enteral Nutrition. 29(5):337-344.

FEEDING AN ELEMENTAL DIET VS A MILK-BASED FORMULA DOES NOT DECREASE INTESTINAL MUCOSAL GROWTH IN INFANT PIGS. - (Peer Reviewed Journal)

Stoll, B., Price, P.T., Reeds, P.J., Chang, X., Henry, J.F., Van Goudoever, J.B., Holst, J.J., Burrin, D.G. 2006. Feeding an elemental diet vs a milk-based formula does not decrease intestinal mucosal growth in infant pigs. Journal of Parenteral and Enteral Nutrition. 30:32-39.

EFFECT OF ORAL N-CARBAMYLGLUTAMATE (NCG) SUPPLEMENTATION ON GROWTH AND TISSUE PROTEIN SYNTHESIS IN PIGLETS - (Abstract Only)

Frank, J., Escobar, J., Suryawan, A., Liu, C., Nguyen, H., Davis, T., Wu, G. 2005. Effect of oral N-carbamylglutamate (NCG) supplementation on growth and tissue protein synthesis in piglets [abstract]. Journal of Animal Science, Proceedings from the 2005 Joint Annual Meeting of the American Dairy Science Association and the American Society of Animal Science. 83(Suppl. 1):abstract 186, p. 118.

CARDIAC AND SKELETAL MUSCLE PROTEIN SYNTHESIS AND ACTIVATION OF TRANSLATION INITIATION FACTORS ARE STIMULATED BY LEUCINE, BUT NOT ISOLEUCINE OR VALINE, IN NEONATAL PIGS - (Abstract Only)

Escobar, J., Frank, J., Suryawan, A., Nguyen, H., Davis, T. 2005. Cardiac and skeletal muscle protein synthesis and activation of translation initiation factors are stimulated by leucine, but not isoleucine or valine, in neonatal pigs [abstract]. Journal of Animal Science, Proceedings from the 2005 Joint Annual Meeting of the American Dairy Science Association and the American Society of Animal Science. 83(Suppl. 1): abstract 390, p. 239.

The nutritional phenotype in the age of metabolomics - (Review Article)

Zeisel, S.H., Freake, H.C., Bauman, D., Bier, D.M., Burrin, D.G., German, J.B., Klein, S., Marquis, G.S., Milner, J.A., Pelto, G.H., Rasmussen, K.M. 2005. The nutritional phenotype in the age of metabolomics. Journal of Nutrition. 135:1613-1616.

PROTEIN SYNTHESIS AND TRANSLATION INITIATION FACTOR ACTIVATION IN NEONATAL PIGS FED INCREASING LEVELS OF DIETARY PROTEIN - (Peer Reviewed Journal)

Frank, J.W., Escobar, J., Suryawan, A., Kimball, S.R., Nguyen, H.V., Jefferson, L.S., Davis, T.A. 2005. Protein synthesis and translation initiation factor activation in neonatal pigs fed increasing levels of dietary protein. Journal of Nutrition. 135(6):1374-1381.

WHOLE-BODY AND HINDLIMB PROTEIN BREAKDOWN ARE DIFFERENTIALLY ALTERED BY FEEDING IN NEONATAL PIGLETS - (Peer Reviewed Journal)

Thivierge, M.C., Bush, J.A., Suryawan, A., Nguyen, H.V., Orellana, R.A., Burrin, D.G., Jahoor, F., Davis, T.A. 2005. Whole-body and hindlimb protein breakdown are differentially altered by feeding in neonatal piglets. Journal of Nutrition. 135(6):1430-1437.

LOCAL IGF-I ENHANCES THE SENSITIVITY OF MUSCLE PROTEIN SYNTHESIS TO INSULIN - (Abstract Only)

Oliver, W.T., Rosenberger, J., Lopez, R., Fiorotto, M.L. 2006. Local IGF-I enhances the sensitivity of muscle protein synthesis to insulin [abstract]. The Federation of American Societies for Experimental Biology Conference: Advancing the Biomedical Frontier, April 1-5, 2006, San Francisco, California. 20(5):Part II, p. A821.

SIGNALING HIERARCHY THAT REGULATES ENDOTHELIAL CELL PROLIFERATION AND VASCULAR REMODELING DURING VASCULOGENESIS - (Abstract Only)

Bohnsack, B.L., Lai, L., Hirschi, K.K. 2005. Signaling hierarchy that regulates endothelial cell proliferation and vascular remodeling during vasculogenesis [abstract]. Journal of Federation of American Societies for Experimental Biology Journal. 19(4):A234.

GLUCAGON-LIKE PEPTIDE 2 DECREASES A MARKER OF BONE RESORPTION IN TPN-FED NEONATAL PIGLETS - (Abstract Only)

Horst, D.A., Sedenquist, M., Stoll, B., Burrin, D.G. 2005. Glucagon-like peptide 2 decreases a marker of bone resorption in tpn-fed neonatal piglets [abstract]. Pediatric Academic Society Meeting. Pediatric Research. 57:Abstract 1609. 2005 CDROM.

CHANGES IN THE PLASMA CITRULLINE CONCENTRATION ARE A PREDICTOR OF ALTERATIONS IN GUT MUCOSAL MORPHOLOGY AND FUNCTIONS IN THE PIGLET. - (Abstract Only)

Lackeyram, D., Burrin, D.G., Mine, Y., Fan, M.Z. 2005. Changes in the plasma citrulline concentration are a predictor of alterations in gut mucosal morphology and functions in the piglet. Journal of Animal Science. 83 (Suppl. 1):207.

MEASURING SPLANCHNIC AMINO ACID METABOLISM BY USING STABLE ISOTOPE TRACERS. - (Abstract Only)

Stoll, B., Burrin, D.G. 2005. Measuring splanchnic amino acid metabolism by using stable isotope tracers [abstract]. Journal of Animal Science. 83(Suppl. 1):242.

INTESTINAL SULFUR AMINO ACID METABOLISM IN NEONATAL PIGLETS - (Abstract Only)

Riedijk, M.A., Stoll, B., Chako, S., Sunehag, A.L., Van Goudoever, J.B., Burrin, D.G. 2005. Intestinal sulfur amino acid metabolism in neonatal piglets [abstract]. Pediatric Research. 57:1608.

DEVELOPMENTAL REGULATION OF PROTEIN KINASE B ACTIVATION IS ISOFORM SPECIFIC IN SKELETAL MUSCLE OF NEONATAL PIGS - (Peer Reviewed Journal)

Suryawan, A., Davis, T.A. 2005. Developmental regulation of protein kinase B activation is isoform specific in skeletal muscle of neonatal pigs. Pediatric Research. 58(4):719-724.

THE GUT METABOLIZES MOST OF THE DIETARY GLUTAMATE EVEN DURING DIETARY EXCESS - (Abstract Only)

Stoll, B., Guan, X., Cottrell, J., Stephens, J., Chang, X., Cui, L., Burrin, D.G. 2005. The gut metabolizes most of the dietary glutamate even during dietary excess. Journal of Federation of American Societies for Experimental Biology. 19(4):A-1695.

FIRST-PASS INTESTINAL METHIONINE METABOLISM IS LIMITED IN ENTERALLY-FED PIGLETS - (Abstract Only)

Riedijk, M.A., Stoll, B., Chako, S., Cottrell, J., Stephens, J., Sunehag, A., Van Goudoever, J.B., Burrin, D.G. 2005. First-pass intestinal methionine metabolism is limited in enterally-fed piglets. Journal of Federation of American Societies for Experimental Biology. 19:A422.

GASTROINTESTINAL GLUCONEOGENESIS IS ABSENT IN THE 36HOUR FASTED PIGLET - (Abstract Only)

Burrin, D.G., Lambert, B., Stoll, B., Guan, X. 2005. Gastrointestinal gluconeogenesis is absent in the 36hour fasted piglet. Journal of Federation of American Societies for Experimental Biology. 19(4):A-420.

GLUCAGON-LIKE PEPTIDE-2 RECEPTOR CO-LOCALIZATION WITH VASOACTIVE NEUROTRANSMITTERS IN THE HUMAN SMALL INTESTINE - (Abstract Only)

Guan, X., Bukowski, J.T., Stephens, J., Niu, S., Zhang, G., Stoll, B., Karpen, H.E., Finegold, M.J., Holst, J.J., Hadsell, D.L., Nichols, B.L., Burrin, D.G. 2005. Glucagon-like peptide-2 receptor co-localization with vasoactive neurotransmitters in the human small intestine. Gastroenterology.

UNDERSTANDING ABNORMALITIES IN VASCULAR SPECIFICATION AND REMODELING - (Review Article)

Enciso, J.M., Hirschi, K.K. 2005. Understanding abnormalities in vascular specification and remodeling. Pediatrics. 116(1):228-230.

THREONINE UTILIZATION IS HIGH IN THE INTESTINE OF PIGLETS - (Peer Reviewed Journal)

Schaart, M.W., Schierbeek, H., Van Der Schoor, S.R., Stoll, B., Burrin, D.G., Reeds, P.J., Van Goudoever, J.B. 2005. Threonine utilization is high in the intestine of piglets. Journal of Nutrition. 135:765-770.

GLP-2 TREATMENT DURING CHRONIC TPN IMPROVES INTESTINAL GLUCOSE UPTAKE AFTER RE-FEEDING IN PIGLETS - (Abstract Only)

Cottrell, J., Stoll, B., Buddington, R., Riedijk, M., Stephens, J., Cui, L., Chang, X., Burrin, D.G. 2005. GLP-2 treatment during chronic tpn improves intestinal glucose uptake after re-feeding in piglets. Journal of Federation of American Societies for Experimental Biology. 19:A1695.

PHYSIOLOGICAL RISE IN PLASMA LEUCINE STIMULATES MUSCLE PROTEIN SYNTHESIS IN NEONATAL PIGS BY ENHANCING TRANSLATION INITIATION FACTOR ACTIVATION - (Peer Reviewed Journal)

Escobar, J., Frank, J.W., Suryawan, A., Nguyen, H.V., Kimball, S.R., Jefferson, L.S., Davis, T.A. 2005. Physiological rise in plasma leucine stimulates muscle protein synthesis in neonatal pigs by enhancing translation initiation factor activation. American Journal of Physiology, Endocrinology, and Metabolism. 288(5):E914-E921.

Red light, green light: Signals that control endothelial cell proliferation during embryonic vascular development - (Review Article)

Bohnsack, B.L., Hirschi, K.K. 2004. Red light, green light: Signals that control endothelial cell proliferation during embryonic vascular development. Cell Cycle. 3(12):1506-1511.

POSTPRANDIAL INTESTINAL AND WHOLE-BODY NITROGEN KINETICS AND DISTRIBUTION IN PIGLETS FED A SINGLE MEAL. - (Peer Reviewed Journal)

Bos, C., Stoll, B., Fouillet, H., Gaudichon, C., Guan, X., Grusak, M.A., Reeds, P.J., Burrin, D.G., Tome, D. 2005. Postprandial intestinal and whole body nitrogen kinetics and distribution in piglets fed a single meal. American Journal of Physiology: Endocrinology and Metabolism. 288(2):E436-E446.

GLUCAGON-LIKE PEPTIDE 2 DOSE-DEPENDENTLY ACTIVATES INTESTINAL CELL SURVIVAL AND PROLIFERATION IN NEONATAL PIGLETS - (Peer Reviewed Journal)

Burrin, D.G., Stoll, B., Guan, X., Cui, L., Chang, X., Holst, J.J. 2005. Glucagon-like peptide 2 dose-dependently activates intestinal cell survival and proliferation in neonatal piglets. Endocrinology. 146:22-32.

METABOLOMICS IN THE OPENING DECADE OF THE 21ST CENTURY: BUILDING THE ROADS TO INDIVIDUALIZED HEALTH. - (Review Article)

German, J.B., Bauman, D.E., Burrin, D.G., King, J.C., Klein, S., Milner, J.A., Pelto, G.H., Rasmussen, K.M., Zeisel, S.H. 2004. Metabolomics in the opening decade of the 21st century: building the roads to individualized health. Journal of Nutrition. 134:2729-2732.

USE OF CHOLECYSTOKININ-OCTAPEPTIDE FOR THE PREVENTION OF PARENTERAL NUTRITION-ASSOCIATED CHOLESTASIS - (Peer Reviewed Journal)

Teitelbaum, D.H., Tracy, T.F., Aouthmany, M.M., Llanos, A., Brown, M.B., Yu, S., Brown, M.R., Shulman, R.J., Hirschl, R.B., Derusso, P.A., Cox, J., Dahlgren, J., Groner, J.I., Strouse, P.J. 2005. Use of cholecystokinin-octapeptide for the prevention of parenteral nutrition-associated cholestasis. Pediatrics. 115(5):1332-1340.

GLUCAGON-LIKE PEPTIDE 2 DOSE-DEPENDENTLY ACTIVATES INTESTINAL CELL SURVIVAL AND PROLIFERATION IN NEONATAL PIGLETS - (Peer Reviewed Journal)

Burrin, D.G., Stoll, B., Guan, X., Cui, L., Holst, J.J. 2004. Glucagon-like peptide 2 dose-dependently activates intestinal cell survival and proliferation in neonatal piglets. Endocrinology. 146(1):22-32.

RELATIVE STIMULATION OF SUPERIOR MESENTERIC ARTERIAL (SMA) BLOOD FLOW BY ENTERAL NUTRITION AND GLUCAGON-LIKE PEPTIDE 2 (GLP-2) IN TOTAL PARENTERAL NUTRITION (TPN) FED NEONATAL PIGLETS - (Abstract Only)

Stephens, J., Stoll, B., Guan, X., Helmrath, M., Burrin, D.G. 2004. Relative stimulation of superior mesenteric arterial (SMA) blood flow by enteral nutrition and glucagon-like peptide 2 (GLP-2) in total parenteral nutrition (TPN) fed neonatal piglets. Gastroenterology. 126(4):A-142(Suppl. 2).

RELATIVE STIMULATION OF SUPERIOR MESENTERIC ARTERIAL (SMA) BLOOD FLOW BY ENTERAL NUTRITION AND GLUCAGON-LIKE PEPTIDE 2 (GLP-2) IN TOTAL PARENTERAL NUTRITION (TPN) FED NEONATAL PIGLETS - (Abstract Only)

Stephens, J., Stoll, B., Guan, X., Helmrath, M., Burrin, D.G. 2004. Relative stimulation of superior mesenteric arterial (SMA) blood flow by enteral nutrition and glucagon-like peptide 2 (GLP-2) in total parenteral nutrition (TPN) fed neonatal piglets [abstract]. Journal of Pediatric Gastroenterology and Nutrition. 39(Supplement 1):S127.

METHODOLOGICAL APPROACHES TO METABOLISM RESEARCH - (Book / Chapter)

Guan, X., Burrin, D.G. 2005. Methodological approaches to metabolism research. In: Burrin, D.G., Mersmann, H.J., editors. Biology of Metabolism in Growing Animals. Biology of Growing Animals Series, Volume 3. London: Elsevier. p. 435-477.

SIGNALING HIERARCHY DOWNSTREAM OF RETINOIC ACID THAT INDEPENDENTLY REGULATES VASCULAR REMODELING AND ENDOTHELIAL CELL PROLIFERATION - (Peer Reviewed Journal)

Bohnsack, B.L., Lai, L., Dolle, P., Hirschi, K.K. 2004. Signaling heirarchy downstream of retinoic acid that independently regulates vascular remodeling and endothelial cell proliferation. Genes and Development. 18(11):1345-1358.

INFLUENCE OF DIETARY PROTEIN AND LACTOSE LEVELS ON PROTEIN SYNTHESIS AND TRANSLATION INITIATION FACTOR ACTIVATION IN NEONATAL PIGS - (Abstract Only)

Frank, J.W., Escobar, J., Suryawan, A., Nguyen, H.V., Liu, C.W., Kimball, S.R., Jefferson, L.S., Davis, T.A. 2004. Influence of dietary protein and lactose levels on protein synthesis and translation initiation factor activation in neonatal pigs [abstract]. Journal of Animal Science, Proceedings of the 2004 Joint Annual Meeting of the American Society of Animal Sciences. 82(Suppl. 1):Abstract 766, p. 419.

INFUSION OF A PHYSIOLOGICAL DOSE OF LEUCINE STIMULATES MUSCLE PROTEIN SYNTHESIS IN NEONATAL PIGS BY ENHANCING THE ACTIVITY OF TRANSLATION INITIATION FACTORS - (Abstract Only)

Escobar, J., Frank, J.W., Kimball, S.R., Suryawan, A., Nguyen, H.V., Liu, C.W., Jefferson, L.S., Davis, T.A. 2004. Infusion of a physiological dose of leucine stimulates muscle protein synthesis in neonatal pigs by enhancing the activity of translation initiation factors [abstract]. Journal of Animal Science, Proceedings of the 2004 Joint Annual Meeting of the American Society of Animal Science. 82(Suppl. 1):abstract 767, p. 419.

RETINOIC ACID SLOWS PROGRESSION AND PROMOTES APOPTOSIS OF SPONTANEOUS PROSTATE CANCER - (Peer Reviewed Journal)

Huss, W.J., Lai, L., Barrios, R.J., Hirschi, K.K., Greenberg, N.M. 2004. Retinoic acid slows progression and promotes apoptosis of spontaneous prostate cancer. The Prostate. 61(2):142-152.

NUTRIENT REGULATION OF CELL CYCLE PROGRESSION - (Review Article)

Bohnsack, B.L., Hirschi, K.K. 2004. Nutrient regulation of cell cycle progression. Annual Review of Nutrition. 24:443-453.

REGULATION OF NEONATAL LIVER PROTEIN SYNTHESIS BY INSULIN AND AMINO ACIDS IN PIGS - (Peer Reviewed Journal)

O'Connor, P.M., Kimball, S.R., Suryawan, A., Bush, J.A., Nguyen, H.V., Jefferson, L.S., Davis, T.A. 2004. Regulation of neonatal liver protein synthesis by insulin and amino acids in pigs. American Journal of Physiology - Endocrinology and Metabolism. 286(6):E994-E1003.

PRIMITIVE ADULT HEMATOPOIETIC STEM CELLS CAN FUNCTION AS OSTEOBLAST PRECURSORS - (Peer Reviewed Journal)

Olmsted-Davis, E.A., Gugala, Z., Camargo, F., Gannon, F.H., Jackson, K., Kienstra, K.A., Shine, H.D., Lindsey, R.W., Hirschi, K., Goodell, M., Brenner, M.K., Davis, A.R. 2003. Primitive adult hematopoietic stem cells can function as osteoblast precursors. Proceedings of the National Academy of Sciences. 100:15877-15882.

RETINOIC ACID REGULATES ENDOTHELIAL CELL PROLIFERATION DURING VASCULOGENESIS - (Peer Reviewed Journal)

Lai, L., Bohnsack, B.L., Niederreither, K., Hirschi, K.K. 2003. Retinoic acid regulates endothelial cell proliferation during vasculogenesis. Development. 130(26):6465-6474.

OUABAIN- AND MARINOBUFAGENIN-INDUCED PROLIFERATION OF HUMAN UMBILICAL VEIN SMOOTH MUSCLE CELLS AND A RAT VASCULAR SMOOTH MUSCLE CELL LINE, A7R5 - (Peer Reviewed Journal)

Abramowitz, J., Dai, C., Hirschi, K., Dmitrieva, R.I., Doris, P.A., Liu, L., Allen, J.C. 2003. Ouabain- and marinobufagenin-induced proliferation of human umbilical vein smooth muscle cells and a rat vascular smooth muscle cell line, A7r5. Circulation. 108(24):3048-3053.

GAP JUNCTION COMMUNICATION MEDIATES TRANSFORMING GROWTH FACTOR-BETA ACTIVATION AND ENDOTHELIAL-INDUCED MURAL CELL DIFFERENTIATION - (Peer Reviewed Journal)

Hirschi, K.K., Burt, J.M., Hirschi, K.D., Dai, C. 2003. Gap junction communication mediates transforming growth factor-beta activation and endothelial-induced mural cell differentiation. Circulation Research. 93(5):429-437.

SMOOTH MUSCLE STEM CELLS - (Review Article)

Hirschi, K.K., Majesky, M.W. 2004. Smooth muscle stem cells. The Anatomical Record. 276A(1):22-33.

PHENOTYPE AND HEMATOPOIETIC POTENTIAL OF SIDE POPULATION CELLS THROUGHOUT EMBRYONIC DEVELOPMENT - (Peer Reviewed Journal)

Nadin, B.M., Goodell, M.A., Hirschi, K.K. 2003. Phenotype and hematopoietic potential of side population cells throughout embryonic development. Blood. 102(7):2436-2443.

THE FAKS ABOUT BLOOD VESSEL ASSEMBLY - (Review Article)

Bohnsack, B.L., Hirschi, K.K. 2003. The FAKs about blood vessel assembly. Circulation Research. 92(3):255-7.

DISTINCT PROGENITOR POPULATIONS IN SKELETAL MUSCLE ARE BONE MARROW DERIVED AND EXHIBIT DIFFERENT CELL FATES DURING VASCULAR REGENERATION - (Peer Reviewed Journal)

Majka, S.M., Jackson, K.A., Kienstra, K.A., Majesky, M.W., Goodell, M.A., Hirschi, K.K. 2003. Distinct progenitor populations in skeletal muscle are bone marrow derived and exhibit different cell fates during vascular regeneration. The Journal of Clinical Investigation. 111(1):71-79.