Epidemiology, Pathogenesis, And Countermeasures To Prevent And Control Avian Metapneumovirus Infection

Docket Number: 16108
Serial Number: 11890314

Summary: Methods and compositions for rapidly identifying CGEPs required for viral infection of mammalian cells are provided. Also provided are methods of inhibiting viral infection of mammalian cells by inhibiting the activity of one or more CGEPs (e.g., as identified in accordance with methods of the invention) in the cells. Aspects of the invention further include specifically identified CGEPs implicated in mammalian cell infection of specific viruses, e.g., African Swine Fever Virus and Foot and Mouth Virus, and methods of modulating their activity to achieve viral resistance. Patent Status: Patent Application Filed on August 2, 2007. Link at USPTO filed under patent title “Methods and compositions for identifying cellular genes exploited by viral pathogens.” Inventors: Laszlo Zsak Endemic Poultry Viral Diseases Research Unit USDA,ARS,SAA, SPRL 934 COLLEGE STATION ROAD ATHENS, GA, 30605 Phone: (706) 546-3654 Fax: (706) 546-3161 Laszlo.Zsak@ars.usda.gov