|Title: Methods for Detection of Prion Protein as an Indication of Transmissible Spongiform Encephalopathies|
US Patent Office Full Record
Methods for Detection of Prion Protein as an Indication of Transmissible Spongiform Encephalopathies
The invention involves a non-invasive method of detecting a specific protein that indicates the presence of transmissible spongiform encephalopathies (TSE) in ruminant animals. The invention uses monoclonal antibodies that bind to a prion protein in animal tissue from sheep, cattle, mule, deer and elk. The invention comprises a non-invasive diagnostic assay using third eyelid lymphoid tissue to detect prion protein in sheep. The invention is a specific, reliable and flexible tool to accurately diagnose TSE. This method is a practical and inexpensive way to test for presence of this potentially fatal neurological disease.
Please refer to USPN 6,514,707, which issued on February 4, 2003, and is a division of USPN 6,165,784, "Antibodies for the Detection of Prion Protein as an Indication of Transmissible Spongiform Encephalopathies," which issued on December 26, 2000.