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United States Department of Agriculture

Agricultural Research Service

Nancy L. Keim

Research Chemist


Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Dietary whole grain-microbiota interactions: Insights into mechanisms for human health - (Peer Reviewed Journal) - (16-Jul-14)
Improved metabolic health alters host metabolism in parallel with changes in systemic xeno-metabolites of gut origin - (Peer Reviewed Journal)
Campbell, C., Grapov, D., Fiehn, O., Chandler, C.J., Burnett, D.J., Souza, E.C., Casazza, G.A., Gustafson, M.B., Keim, N.L., Newman, J.W., Hunter, G.R., Fernandez, J.R., W. Timothy, G., Harper, M., Hoppel, C.L., Meissen, J.K., Take, K., Adams, S.H. 2014. Improved metabolic health alters host metabolism in parallel with changes in systemic xeno-metabolites of gut origin. PLoS One. 9(1):e84260. DOI: 10.1371/journal.pone.0084260.
Association between subcutaneous white adipose tissue and serum 25-hydroxyvitamin D in overweight and obese adults - (Peer Reviewed Journal)
Piccolo, B.D., Dolnikowski, G., Seyoum, E., Thomas, A., Gertz, E.R., Souza, E.C., Keim, N.L., Adams, S.H., Newman, J.W., Woodhouse, L.R., Van Loan, M.D. 2013. Association between subcutaneous white adipose tissue and serum 25-hydroxyvitamin D in overweight and obese adults. American Journal of Clinical Nutrition. 5(9), 3352-3366. DOI:10.3390/nu5093352.
Vegetable variety is a key to improved diet quality in low-income women in California - (Peer Reviewed Journal) - (08-Jul-13)
Effects of sugar-sweetened beverages on plasma acylation stimulating protein, leptin, and adiponectin: Relationships with metabolic outcomes - (Peer Reviewed Journal)
Resvani, R., Cianflone, K., Mcgahan, J.P., Berglund, L., Bermer, A.A., Keim, N.L., Griffen, S.C., Havel, P.J., Stanhope, K.L. 2013. Effects of sugar-sweetened beverages on plasma acylation stimulating protein, leptin, and adiponectin: Relationships with metabolic outcomes. Obesity. 10.1002.
Estimating dietary costs of low-income women in California: A comparison of two approaches - (Peer Reviewed Journal)
Aaron, G., Keim, N.L., Drewnowski, A., Townsend, M. 2013. Estimating dietary costs of low-income women in California: A comparison of two approaches. American Journal of Clinical Nutrition. 97(4):835:841.
Dairy food consumption and meal-induced cortisol response interact to influence weight loss in overweight women undergoing a 12-week meal-controlled weight loss intervention - (Peer Reviewed Journal)
Witbracht, M., Van Loan, M.D., Adams, S.H., Keim, N.L., Laugero, K.D. 2012. Dairy food consumption and meal-induced cortisol response interact to influence weight loss in overweight women undergoing a 12-week meal-controlled weight loss intervention. Journal of Nutrition. 143(1):45-52.
Energy assessment: physical activity - (Book / Chapter) - (31-Aug-12)
Variations in metabolic responses to meal challenges differing in glycemic index in healthy women: Is it meaningful? - (Peer Reviewed Journal)
Krishnan, S., Newman, J.W., Hembrooke, T.A., Keim, N.L. 2012. Variations in metabolic responses to meal challenges differing in glycemic index in healthy women: Is it meaningful?. Nutrition and Metabolism. 9:26.
Variation in metabolic responses to meal challenges differing in glycemic index in healthy women: Is it meaningful? - (Peer Reviewed Journal)
Krishnan, S., Newman, J.W., Hembrooke, T.A., Keim, N.L. 2012. Variation in metabolic responses to meal challenges differing in glycemic index in healthy women: Is it meaningful?. Journal of Nutrition and Metabolism. 9(1):26.
Association between vitamin D metabolites in fat tissue and serum 25-hydroxy vitamin D in overweight and obese adults - (Abstract Only)
Piccolo, B.D., Gertz, E.R., Thomas, A.P., Keim, N.L., Adams, S.H., Seyoum, E., Dolnikowski, G., Van Loan, M.D. 2012. Association between vitamin D metabolites in fat tissue and serum 25-hydroxy vitamin D in overweight and obese adults. Journal of Federation of American Societies for Experimental Biology. 386.4.
Within subject variation of satiety hormone responses to a standard lunch - (Abstract Only)
Forester, S.M., Witbracht, M., Horn, W.F., Keim, N.L., Laugero, K.D. 2012. Within subject variation of satiety hormone responses to a standard lunch. Journal of Federation of American Societies for Experimental Biology. 639.5.
Increased dietary saturated fat intake is negatively associated with compliance to exercise regimen and improvement in fitness parameters. - (Abstract Only)
Krishnan, S., Gustafson, M., Sheets, C., Souza, E., Keim, N.L. 2012. Increased dietary saturated fat intake is negatively associated with compliance to exercise regimen and improvement in fitness parameters.. Journal of Federation of American Societies for Experimental Biology. 257.4.
Skipping breakfast is associated with lower physical activity energy expenditure in young healthy women - (Abstract Only)
Marquez, A.P., Forester, S., Witbracht, M., Campbell, C., Gustafson, M., Keim, N.L. 2012. Skipping breakfast is associated with lower physical activity energy expenditure in young healthy women. Journal of Federation of American Societies for Experimental Biology. 820.21.
Circulating concentrations of monocyte chemoattranctant protein-1, plasminogen activator inhibitor-1, & soluble leukocyte adhesion molecule-1 in overweight/obese men/women consuming fructose-or glucose-sweetened beverages Reprint Icon - (Peer Reviewed Journal)
Cox, C.L., Stanhope, K.L., Marc Schwarz, J., Graham, J.L., Griffen, S.C., Bremer, A.A., Berglund, L., Mcgahan, J.P., Beysen, C., Keim, N.L., Havel, P.J. 2011. Circulating concentrations of monocyte chemoattranctant protein-1, plasminogen activator inhibitor-1, & soluble leukocyte adhesion molecule-1 in overweight/obese men/women consuming fructose-or glucose-sweetened beverages. Journal of Clinical Endocrinology and Metabolism. 96(12):E2034-E2038.
Assessing face validity of a physical activity questionnaire for Spanish-speaking women in California - (Peer Reviewed Journal)
Banna, J.C., Keim, N.L., Townsend, M.S. 2011. Assessing face validity of a physical activity questionnaire for Spanish-speaking women in California. Journal of Extension. Vol.49:5.
Consumption of fructose-sweetened beverages for 10 weeks reduces net fat oxidation and energy expenditure in overweight/obese men and women Reprint Icon - (Peer Reviewed Journal)
Cox, C., Stanhope, K.L., Schwarz, J.M., Graham, J.L., Havel, P.J., Keim, N.L. 2011. Consumption of fructose-sweetened beverages for 10 weeks reduces net fat oxidation and energy expenditure in overweight/obese men and women. American Journal of Clinical Nutrition. Eur J Clin Nutr. 2012 Feb;66(2):201-8.
Consumption of fructose and high fructose corn syrup increase postprandial triglycerides, LDL-cholestrol, and apolipoprotein-b in young men and women - (Peer Reviewed Journal)
Stanhope, K., Bremer, A.A., Natkajima, K., Ito, Y., Nakano, T., Chen, G., Fong, T.H., Lee, V., Menorca, R., Keim, N.L., Havel, P.J. 2011. DIFFERENTIAL EFFECTS OF CONSUMING GLUCOSE-, FRUCTOSE-, AND HIGH FRUCTOSE CORN SYRUP-SWEETENED BEVERAGES FOR 2 WEEKS ON FASTING AND POSTPRANDIAL LIPID AND LIPOPROTEIN PROFILES IN YOUNG MEN AND WOMEN. Journal of Clinical Endocrinology and Metabolism. 96(10):E1596-1605.
Dairy foods in a moderate energy restricted diet do not enhance central fat, weight & intra-abdominal adipose tissue loss or reduce adipocyte size & inflammatory markers in overweight & obese adults; Controlled feeding study - (Peer Reviewed Journal)
Van Loan, M.D., Keim, N.L., Adams, S.H., Souza, E., Woodhouse, L.R., Thomas, A., Witbracht, M., Gertz, E.R., Piccolo, B., Brenner, A.R., Spurlock, M. 2011. Dairy foods in a moderate energy restricted diet do not enhance central fat, weight & intra-abdominal adipose tissue loss or reduce adipocyte size & inflammatory markers in overweight & obese adults; Controlled feeding study. Journal of Obesity. 10.1155/2011/989657.
Performance on the Iowa gambling task is related to magnitude of weight loss and salivary cortisol in a diet-induced weight loss intervention in overweight women Reprint Icon - (Peer Reviewed Journal)
Witbracht, M.G., Laugero, K.D., Van Loan, M.D., Adams, S.H., Keim, N.L. 2011. PERFORMANCE ON THE IOWA GAMBLING TASK IS RELATED TO MAGNITUDE OF WEIGHT LOSS AND SALIVARY CORTISOL IN A DIET-INDUCED WEIGHT LOSS INTERVENTION IN OVERWEIGHT WOMEN. Physiology and Behavior. 10.1016/j.physbeh.2011.04.035.
Metabolic responses to prolonged consumption of glucose- and fructose-sweetened beverages are not associated with postprandial or 24-hour glucose and insulin excursions Reprint Icon - (Peer Reviewed Journal)
Stanhope, K., Griffin, S.C., Bremer, A.A., Schaefer, E., Natkajima, K., Schwarz, J.M., Beysen, C., Berglund, L., Keim, N.L., Havel, P.J. 2011. METABOLIC RESPONSES TO PROLONGED CONSUMPTION OF GLUCOSE- AND FRUCTOSE-SWEETENED BEVERAGES ARE NOT ASSOCIATED WITH POSTPRANDIAL OR 24-HOUR GLUCOSE AND INSULIN EXCURSIONS. American Journal of Clinical Nutrition. 94:112-119.
Translating the Dietary Guidelines for Americans 2010 to Bring About Real Behavior Change - (Peer Reviewed Journal)
Rowe, S., Alexander, N., Almeida, N., Black, R., Burns, R., Bush, L., Crawford, P., Keim, N.L., Kris-Etherton, P., Weaver, C. 2011. Translating the Dietary Guidelines for Americans 2010 to Bring About Real Behavior Change. Journal of American Dietetic Association. 111(1):28-39.
In polycystic ovary syndrome, adrenal steroids are regulated differently in the morning versus in response to nutrient intake Reprint Icon - (Peer Reviewed Journal)
Gurusinghe, D., Gill, S., Almario, R.U., Lee, J., Horn, W.F., Keim, N.L., Kim, K., Kasim-Karakas, S.E. 2009. In polycystic ovary syndrome, adrenal steroids are regulated differently in the morning versus in response to nutrient intake. Fertility and Sterility, 93(4):1192-1193, 2009.
Effects of consuming fructose- or glucose-sweetened beverages for 10 weeks on lipids, insulin sensitivity and adiposity Reprint Icon - (Peer Reviewed Journal)
Stanhope, K.L., Keim, N.L., Griffen, S.C., Bremer, A.A., Graham, J.L., Hatcher, B., Cox, C., Mcgahan, J.P., Seibert, A., Krauss, R.M., Chiu, S., Schaefer, E.J., Ai, M., Otokozawa, S., Nakajima, K., Nakano, T., Beysen, C., Schwarz, J.M., Hellerstein, M.K., Berglund, L., Havel, P.J. 2009. Effects of consuming fructose- or glucose-sweetened beverages for 10 weeks on lipids, insulin sensitivity and adiposity. Journal of Clinical Investigation. 119(5):1322-1334, 2009.
Endocrine and metabolic effects of consuming fructose- and glucose-sweetened beverages with meals in obese men and women: Influence of insulin resistance on plasma triglyceride responses Reprint Icon - (Peer Reviewed Journal)
Teff, K.L., Grudziak, J., Townsend, R.R., Dunn, T.N., Grant, R.W., Adams, S.H., Keim, N.L., Cummings, B.P., Stanhope, K.L., Havel, P.J. 2009. Endocrine and metabolic effects of consuming fructose- and glucose-sweetened beverages with meals in obese men and women: Influence of insulin resistance on plasma triglyceride responses. J. Clin Endocrinol Metab. 94(5):1562-1959.
Less-energy-dense diets of low-income women in California are associated with higher energy-adjusted diet costs Reprint Icon - (Peer Reviewed Journal)
Townsend, M., Grant, A., Monsivais, P., Keim, N.L., Drewnowski, A. 2009. Lower-energy-density diets of low-income women in California are associated with higher energy-adjusted diet costs. American Journal of Clinical Nutrition. 89:1220-1226, 2009.
Glycemic Index, Cholecystokinin, Satiety and Disinhibition: Is There An Unappreciated Paradox for Overweight Women? - (Peer Reviewed Journal)
Burton-Freeman, B., Keim, N.L. 2008. GLYCEMIC INDEX, CHOLECYSTOKININ, SATIETY AND DISINHIBITION: IS THERE AN UNAPPRECIATED PARADOX FOR OVERWEIGHT WOMEN? International Journal of Obesity. 32:1647-1654.
Consumption of Fructose- But not Glucose-Sweetened Beverages for 10 Weeks Increases Postprandial Triglyceride and Apolipoprotein B Concentrations in Overweight/Obese Women Reprint Icon - (Peer Reviewed Journal)
Swarbrick, M.M., Stanhope, K.L., Elliott, S.S., Graham, J.L., Krauss, R.M., Christiansen, M.P., Griffen, S.C., Keim, N.L., Havel, P.J. 2008. Consumption of Fructose- But not Glucose-Sweetened Beverages for 10 Weeks Increases Postprandial Triglyceride and Apolipoprotein B Concentrations in Overweight/Obese Women. Journal of Clinical Endocrinology and Metabolism. 100:947-952, 2008.
Twenty-four Hour Endocrine and Metabolic Profiles Following Consumption of High Fructose Corn Syrup-, Sucrose- Fructose-, and Glucose-Sweetened Beverages with Meals Reprint Icon - (Peer Reviewed Journal)
Stanhope, K.L., Griffen, S.C., Bair, B.R., Swarbrick, M.M., Keim, N.L., Havel, P.J. 2008. Twenty-four Hour Endocrine and Metabolic Profiles Following Consumption of High Fructose Corn Syrup-, Sucrose- Fructose-, and Glucose-Sweetened Beverages with Meals. American Journal of Clinical Nutrition. Amer. J. Clin. Nutr., 87:1194-1203, 2008.
Response of Selenium Status Indicators to Supplementation of Healthy North American Men with High-Selenium Yeast Reprint Icon - (Peer Reviewed Journal)
Hawkes, W.C., Keim, N.L., Richter, D., Gustafson, M.B., Gale, B., Mackey, B.E., Bonnel, E. 2008. Response of selenium status indicators to supplementation of healthy north american men with high-selenium yeast. Journal of Trace Elements in Medicine and Biology. Vol.122:107-121, 2008.
Postprandial Monocyte Activation in Response to Meals with High and Low Glycemic Loads in Overweight Women Reprint Icon - (Peer Reviewed Journal)
Keim, N.L., Motton, D.D., Tenorio, F.A., Horn, W.F., Rutledge, J.C. 2007. POSTPRANDIAL MONOCYTE ACTIVATION IN RESPONSE TO MEALS WITH HIGH AND LOW GLYCEMIC LOADS IN OVERWEIGHT WOMEN. American Journal of Clinical Nutrition. 85:60-65, 2007.
Best Practice Methods to Apply to Measurement of Resting Metabolic Rate, a Systematic Review Reprint Icon - (Peer Reviewed Journal)
Compher, C., Frankenfield, D., Keim, N.L., Roth-Yousey, L. Best practice methods to apply to measurement of resting metabolic rate, a systematic review. Journal Of The American Dietetic Association. 106:881-903, 2006.
Raman Spectroscopic Analysis of Biochemical Changes in Individual Triglyceride-Rich Lipoproteins in the Pre and Postprandial State. Reprint Icon - (Peer Reviewed Journal)
Chan, J.W., Motton, D., Rutledge, J.C., Keim, N.L., Huser, T. Raman spectroscopic analysis of biochemical changes in individual triglyceride-rich lipoproteins in the pre- and postprandial state.. Analytical Chemistry 77:5870-5876, 2005.
Visually Enhanced Evaluation for Low-Income Clients - (Abstract Only)
Townsend, M.S., Silva, K., Follett, J.R., Keim, N.L., Martin, A.C., Metz, D.L., Swanson-Wooten, P.C., Sugarman, S.B. Visually enhanced evaluation for low-income clients. Journal of Nutrition Education and Behavior. 2005; vol.37 Suppl 1:S49
Fructose - (Book / Chapter)
Keim, N.L., Havel, P.J. Fructose. Encyclopedia of Human Nutrition, 2nd edition. Elsevier Ltd. 2005, Vol.2;351-356.
Carbohydrates - (Book / Chapter)
Keim, N.L., Levin, R.J., Havel, P.J. Carbohydrates. Modern Nutrition in Health and Disease, 10th edition, Lippincott Williams & Williams, 2005. Pp. 62-82.
Size Acceptance and Intuitive Eating Improve Health for Obese Female Chronic Dieters Reprint Icon - (Peer Reviewed Journal)
Bacon, L., Stern, J.S., Van Loan, M.D., Keim, N.L. Size acceptance and intuitive eating improves health for obese female chronic dieters. Journal Of The American Dietetic Association. J Am Diet Assoc. 105(6):929-936, 2005.
American's Obesity Epidemic: Measuring Physical Activity to Promote An Active Lifestyle - (Peer Reviewed Journal)
Keim, N.L., Blanton, C.A., Kretsch, M.J. American's obesity epidemic: measuring physical activity to promote an active lifestyle. Journal Of The American Dietetic Association. J Am Diet Assoc. 2004;104:1398-1409.
Restrained Eating Behavior and the Metabolic Response to Dietary Energy Restriction in Women - (Peer Reviewed Journal)
Keim, N.L., Horn, W.F. 2004. Restrained eating behavior and the metabolic response to dietary energy restriction in women. Obesity Research. 12(1), 2004.
Dietary Fructose Reduces Circulating Insulin and Leptin, Attenuates Postprandial Suppression of Ghrelin and Increases Triglycerides in Women Reprint Icon - (Peer Reviewed Journal)
Teff, K.T., Elliott, S.S., Tschoep, M., Rader, D., Heiman, M., Townsend, R.R., Keim, N.L., D'Alessio, D., Havel, P.J. 2004. Consuming high-fructose beverages with meals reduces circulating insulin and leptin concentrations and raises plasma ghrelin and triglycerides in normal weight women. Clinical Endocrine Metabolism. 89(6):2963-2972, 2004.
Low Bone Mass in Pre-Menopausal Chronic Dieting Obese Women - (Peer Reviewed Journal)
Van Loan, M.D., Keim, N.L., Stern, J., Bacon, L. 2004. Low bone mass in pre-menopausal chronic dieting obese women. European Journal of Clinical Nutrition. European Journal of Clinical Nutrition. 58:966-971.
Dietary Selenium Intake Modulates Thyroid Hormone and Energy Metabolism in Men - (Peer Reviewed Journal)
Hawkes, W.C., Keim, N.L. 2003. Dietary selenium intake modulates thyroid hormone and energy metabolism in men. Journal of Nutrition. 133:3443-3448, 2003.
Fructose, Weight Gain, and the Insulin Resistance Syndrome - (Peer Reviewed Journal)
Elliott, S.S., Keim, N.L., Stern, J., Teff, K., Havel, P.J. 2002. FRUCTOSE, WEIGHT GAIN, AND THE INSULIN RESISTANCE SYNDROME. American Journal of Clinical Nutrition 76:911-922, 2002.
Evaluating a 'non-Diet' Wellness Intervention for Improvement of Metabolic Fitness, Psychological Well-Being and Eating and Activity Behaviors - (Peer Reviewed Journal)
Bacon, L., Keim, N.L., Van Loan, M.D., Derricote, M., Gale, B., Kazaks, A., Stern, J.S. 2002. EVALUATING A 'NON-DIET' WELLNESS INTERVENTION FOR IMPROVEMENT OF METABOLIC FITNESS, PSYCHOLOGICAL WELL-BEING AND EATING AND ACTIVITY BEHAVIORS. International Journal of Obesity 26:854-865, 2002.
Relation Between Circulating Leptin Concentrations and Appetite During a Prolonged, Moderate Energy Deficit in Women - (Peer Reviewed Journal) - (10-May-98)
Weight Loss Increased with Consumption of Large Morning Meals and Fat-Free Mass Is Preserved with Large Meals Evening in Women on a Controlled Weight Reduction Regimen - (Peer Reviewed Journal) - (26-Sep-96)
The Effects of Dietary Selenium on Thyroid Hormones, Energy Metabolism, Semen Quality, and Immune Funciton in Healthy Men - (Abstract Only) - (18-Aug-96)
The Effects of Cross-Training on Energy Expenditure and Utilization of Overweight Women - (Abstract Only) - (30-May-96)
Time of Meal Ingestion Affects Loss of Weight and Fat-Free Mass (Ffm) in Women - (Abstract Only) - (15-Feb-96)
Last Modified: 11/17/2011
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