Projects

STRATEGIES TO CONTROL AND PREVENT BACTERIAL INFECTIONS IN SWINE Appropriated (D)   Accession Number: 421211

COMPARISON OF PORCINE HIGH FEVER DISEASE ISOLATES OF PRRSV TO US ISOLATES FOR THEIR ABILITY TO CAUSE SECONDARY BACTERIAL INFECTION IN SWINE Reimbursable (R)   Accession Number: 422165

H1N1 INFLUENZA A VIRUS IN SWINE SUPPLEMENTAL RESEARCH PROGRAM Specific Cooperative Agreement (S)   Accession Number: 419005

SIV EPITOPES AND GENETIC FACTORS THAT AFFECT SURVEILLANCE AND IMMUNITY ELICITED BY INFLUENZA VACCINES AGAINST EMERGING INFLUENZA STRAINS Specific Cooperative Agreement (S)   Accession Number: 419073

H1N1 INFLUENZA A VIRUS IN SWINE SUPPLEMENTAL RESEARCH PROGRAM Other (X)   Accession Number: 418864

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Divergent immune responses and disease outcomes in piglets immunized with inactivated and attenuated H3N2 swine influenza vaccines in the presence of maternally-derived antibodies - (Abstract Only) - (14-Mar-13)

Overview of swine influenza virus vaccine research and technology: What's on the horizon and what do we need to move forward? - (Proceedings)

Kehrli, Jr., M.E., Vincent, A.L., Gauger, P.C., Kitikoon, P., Anderson, T.K., Loving, C.L., Lager, K.M. 2013. Overview of swine influenza virus vaccine research and technology: What's on the horizon and what do we need to move forward? In: Proceedings of 44th Annual Meeting of the American Association of Swine Veterinarians, San Diego, CA. p. 517-519.

Cross-reactive immune responses following vaccination with a live-attenuated influenza virus compared to adjuvanted, whole-inactivated virus in pigs - (Abstract Only)

Loving, C.L., Braucher, D.R., Brockmeier, S.L., Vincent, A.L. 2012. Cross-reactive immune responses following vaccination with a live-attenuated influenza virus compared to adjuvanted, whole-inactivated virus in pigs. Immunological Mechanisms of Vaccination, Keystone Symposia. Paper No. 2038.

Changes in circulating and thymic lymphocyte populations following infection with strains of North American or highly pathogenic PRRSV - (Abstract Only)

Loving, C.L., Brockmeier, S.L., Palmer, M.V., Spear, A.R., Faaberg, K.S., Nicholson, T.L. 2012. Changes in circulating and thymic lymphocyte populations following infection with strains of North American or highly pathogenic PRRSV. International PRRS Symposium 2012. Poster No. 77.

Comparison of the pathogenesis of Asian highly-pathogenic PRRSV isolates to U.S. isolates and their ability to cause secondary bacterial infection in swine - (Abstract Only)

Brockmeier, S.L., Loving, C.L., Palmer, M.V., Spear, A.R., Faaberg, K.S., Nicholson, T.L. 2012. Comparison of the pathogenesis of Asian highly-pathogenic PRRSV isolates to U.S. isolates and their ability to cause secondary bacterial infection in swine. International PRRS Symposium 2012. Poster No. 64.

Changes in circulating and thymic lymphocyte populations following infection with strains of North American or highly pathogenic PRRSV - (Abstract Only)

Loving, C.L., Brockmeier, S.L., Palmer, M.V., Spear, A.R., Faaberg, K.S., Nicholson, T.L. 2012. Changes in circulating and thymic lymphocyte populations following infection with strains of North American or highly pathogenic PRRSV. Conference of Research Workers in Animal Diseases Annual Meeting. Paper No. 185.

Comparison of Asian highly-pathogenic PRRSV isolates to US isolates for their ability to cause secondary bacterial infection in swine - (Abstract Only)

Brockmeier, S.L., Loving, C.L., Palmer, M.V., Spear, A.R., Faaberg, K.S., Nicholson, T.L. 2012. Comparison of Asian highly-pathogenic PRRSV isolates to US isolates for their ability to cause secondary bacterial infection in swine. Conference of Research Workers in Animal Diseases. Paper No. 184.

Biotherapeutics as alternatives to antibiotics: Effects of adenoviral delivered cytokines on innate and adaptive immunity - (Abstract Only) - (12-Sep-12)

Intranasal vaccination with replication defective adenovirus-5 encoding influenza hemagglutinin elicits protective immunity to homologous challenge and partial protection to heterologous challenge in pigs - (Peer Reviewed Journal)

Braucher, D.R., Henningson, J.N., Loving, C.L., Vincent, A.L., Kim, E., Steitz, J., Gambotto, A.A., Kehrli, Jr., M.E. 2012. Intranasal vaccination with replication-defective adenovirus type 5 encoding influenza virus hemagglutinin elicits protective immunity to homologous challenge and partial protection to heterologous challenge in pigs. Clinical and Vaccine Immunology. 19(11):1722-1729.

Genomic sequence and virulence comparison of four type 2 porcine reproductive and respiratory syndrome virus strains - (Peer Reviewed Journal)

Brockmeier, S.L., Loving, C.L., Vorwald, A.C., Kehrli, Jr., M.E., Baker, R.B., Nicholson, T.L., Lager, K.M., Miller, L.C., Faaberg, K.S. 2012. Genomic sequence and virulence comparison of four Type 2 porcine reproductive and respiratory syndrome virus strains. Virus Research. 169(1):212-221.

Strain-dependent effects of PB1-F2 of triple reassortant H3N2 influenza viruses in swine - (Peer Reviewed Journal)

Pena, L., Vincent, A.L., Loving, C.L., Henningson, J.N., Lager, K.M., Perez, D.R. 2012. Strain-dependent effects of PB1-F2 of triple reassortant H3N2 influenza viruses in swine. Journal of General Virology. 93(10):2204-2214.

Live attenuated influenza vaccine provides superior protection from heterologous infection in pigs with maternal antibodies without inducing vaccine associated enhanced respiratory disease (VAERD) - (Peer Reviewed Journal)

Vincent, A.L., Ma, W., Lager, K.M., Richt, J.A., Janke, B.H., Sandbulte, M.R., Gauger, P.C., Loving, C.L., Webby, R.J., Garcia-Sastre, A. 2012. Live attenuated influenza vaccine provides superior protection from heterologous infection in pigs with maternal antibodies without inducing vaccine associated enhanced respiratory disease. Journal of Virology. 86(19):10597-10605.

Heightened adaptive immune responses following vaccination with a temperature-sensitive, live-attenuated influenza virus compared to adjuvanted, whole-inactivated virus in pigs - (Peer Reviewed Journal)

Loving, C.L., Vincent, A.L., Pena, L., Perez, D.R. 2012. Heightened adaptive immune responses following vaccination with a temperature-sensitive, live-attenuated influenza virus compared to adjuvanted, whole-inactivated virus in pigs. Vaccine. 30(40):5830-5838.

Biotherapeutics as alternatives to antibiotics: effects of IFN-a and G-CSF on innate and adaptive immunity in swine - (Abstract Only) - (16-Jun-12)

Comparison of human-like H1 (delta-cluster) influenza A viruses in the swine host - (Peer Reviewed Journal)

Ciacci Zanella, J.R., Vincent, A.L., Zanella, E.L., Lorusso, A., Loving, C.L., Brockmeier, S.L., Gauger, P.C., Janke, B.H., Gramer, M.R. 2012. Comparison of human-like H1 (delta-cluster) influenza A viruses in the swine host. Influenza Research and Treatment. Available: http://www.hindawi.com/journals/irt/2012/329029/.

Influenza A virus and secondary bacterial infection in swine - (Abstract Only) - (02-Apr-12)

Restored PB1-F2 into the 2009 pandemic H1N1 influenza virus has minimal effects in swine - (Peer Reviewed Journal)

Pena, L., Vincent, A.L., Loving, C.L., Henningson, J.N., Lager, K.M., Lorusso, A., Perez, D.R. 2012. Restored PB1-F2 into the 2009 pandemic H1N1 influenza virus has minimal effects in swine. Journal of Virology. 86(10):5523-5532.

The presence of alpha interferon at the time of infection alters the innate and adaptive immune responses to porcine reproductive and respiratory syndrome virus - (Peer Reviewed Journal)

Brockmeier, S.L., Loving, C.L., Nelson, E.A., Miller, L.C., Nicholson, T.L., Register, K.B., Grubman, M.J., Brough, D.E., Kehrli, Jr., M.E. 2012. The presence of alpha interferon at the time of infection alters the innate and adaptive immune responses to porcine reproductive and respiratory syndrome virus. Clinical and Vaccine Immunology. 19(4):508-514.

Effects of interferon-alpha on the immune response to porcine reproductive and respiratory syndrome virus - (Peer Reviewed Journal) - (01-Jan-12)

Phenotypic modulation of the Bvg+ phase is not required for pathogenesis and transmission of Bordetella bronchiseptica in swine - (Peer Reviewed Journal)

Nicholson, T.L., Brockmeier, S.L., Loving, C.L., Register, K.B., Kehrli, Jr., M.E., Stibitz, S.E., Shore, S.M. 2012. Phenotypic modulation of the virulent Bvg phase is not required for pathogenesis and transmission of Bordetella bronchiseptica in swine. Infection and Immunity. 80(3):1025-1036.

Vaccination with NS1-truncated H3N2 swine influenza virus primes T cells and confers cross-protection against an H1N1 heterosubtypic challenge in pigs - (Peer Reviewed Journal)

Kappes, M.A., Sandbulte, M.R., Platt, R., Wang, C., Lager, K.M., Henningson, J.N., Lorusso, A., Vincent, A.L., Loving, C.L., Roth, J.A., Kehrli Jr, M.E. 2012. Vaccination with NS1-truncated H3N2 swine influenza virus primes T cells and confers cross-protection against an H1N1 heterosubtypic challenge in pigs. Vaccine. 30(2):280-288.

Influenza A virus in pigs – protection, provocation and predisposition - (Abstract Only) - (13-Oct-11)

Enhancement of innate immunity with granulocyte colony-stimulating factor did not prevent disease in pigs infected with a highly pathogenic Chinese PRRSV strain - (Abstract Only)

Schlink, S.N., Lager, K.M., Brockmeier, S.L., Loving, C.L., Henningson, J.N., Faaberg, K.S., Guo, B., Miller, L.C., Vorwald, A.C., Kehrli, Jr., M.E. 2011. Enhancement of innate immunity with granulocyte colony-stimulating factor did not prevent disease in pigs infected with a highly pathogenic Chinese PRRSV strain. 2011 International PRRS Symposium. Paper No. 59. page 76.

Modified live virus vaccine induces a distinct immune response profile compared to inactivated influenza A virus vaccines in swine - (Abstract Only)

Gauger, P., Vincent, A., Loving, C., Lorusso, A., Lager, K., Pena, L., Perez, D. 2011. Modified live virus vaccine induces a distinct immune response profile compared to inactivated influenza A virus vaccines in swine [abstract]. Conference of Research Workers in Animal Diseases. Paper No. 148.

Sequence and virulence comparison of four North American isolates of porcine reproductive and respiratory syndrome virus - (Abstract Only)

Brockmeier, S.L., Loving, C.L., Miller, L.C., Vorwald, A.C., Kehrli, Jr., M.E., Baker, R.B., Nicholson, T.L., Lager, K.M., Faaberg, K.S. 2011. Sequence and virulence comparison of four North American isolates of porcine reproductive and respiratory syndrome virus. Conference of Research Workers in Diseases. Paper No. 174. p. 171.

Intranasal vaccination with Ad5-encoding influenza HA elicits sterilizing immunity to homologous challenge and partial protection to heterologous challenge in pigs - (Abstract Only)

Braucher, D.R., Henningson, J.N., Loving, C.L., Vincent, A.L., Kim, E., Steitz, J., Gambotto, A.A., Kehrli, Jr., M.E. 2011. Intranasal vaccination with Ad5-encoding influenza HA elicits sterilizing immunity to homologous challenge and partial protection to heterologous challenge in pigs [abstract]. Conference of Research Workers in Animal Diseases. Paper No. 131.

Host response to secondary bacterial infection associated with antecedent influenza virus infection in pigs – exacerbation associated with vaccination - (Abstract Only)

Loving, C.L., Vincent, A.L., Brockmeier, S.L., Henningson, J.N., Braucher, D.R., De Souza Rajao, D. 2011. Host response to secondary bacterial infection associated with antecedent influenza virus infection in pigs - exacerbation associated with vaccination [abstract]. Autumn Immunology Conference. Poster No. 140.

DNA vaccination elicits protective immune responses against pandemic and classic swine influenza viruses in pigs - (Peer Reviewed Journal)

Gorres, J.P., Lager, K.M., Kong, W.P., Royals, M., Todd, J.P., Vincent, A.L., Wei, C.J., Loving, C.L., Zanella, E.L., Janke, B., Kehrli, Jr., M.E., Nabel, G.J., Rao, S.S. 2011. DNA vaccination elicits protective immune responses against pandemic and classic swine influenza viruses in pigs. Clinical and Vaccine Immunology. 18(11):1987-1995.

Bordetellosis - (Book / Chapter)

Brockmeier, S.L., Register, K.B., Nicholson, T.L., Loving, C.L. 2012. Bordetellosis. In: Zimmerman, J., Karriker, L., Ramirez, A., Schwartz, K., Stevenson, G., editors.Diseases of Swine. 10th edition. Ames, IA: Iowa State University Press. pp. 670-679.

Comparison of Humoral and Cellular Immune Responses to Inactivated Swine Influenza Virus Vaccine in Weaned Pigs - (Peer Reviewed Journal)

Platt, R., Vincent, A.L., Gauger, P.C., Loving, C.L., Zanella, E.L., Lager, K.M., Kehrli, Jr., M.E., Kimura, K., Roth, J.A. 2011. Comparison of humoral and cellular immune responses to inactivated swine influenza virus vaccine in weaned pigs. Veterinary Immunology and Immunopathology. 142(3-4):252-257.

HP-PRRSV challenge of 4 and 10-week-old pigs - (Proceedings)

Lager, K.M., Faaberg, K.S., Guo, B., Brockmeier, S., Henningson, J.N., Schlink, S.N., Miller, L.C., Kappes, M.A., Kehrli, Jr., M.E., Loving, C.L., Nicholson, T.L., Yang, H.C. 2011. HP-PRRSV challenge of 4 and 10-week-old pigs. In: Proceedings of the 5th Asian PRRSpective Symposium, May 10, 2011, Bangkok, Thailand. 6 pages.

Contribution of Bordetella bronchiseptica Type III secretion system to respiratory disease in swine - (Abstract Only)

Brockmeier, S., Nicholson, T.L., Loving, C.L., Register, K.B. 2011. Contribution of Bordetella bronchiseptica type III secretion system to respiratory disease in swine [abstract]. American Society for Microbiology 2011 Annual Meeting. Abstract No. 1494.

Enhanced pneumonia and disease in pigs vaccinated with an inactivated human-like (delta-cluster) H1N2 vaccine and challenged with pandemic 2009 H1N1 influenza virus - (Peer Reviewed Journal)

Gauger, P.C., Vincent, A.L., Loving, C.L., Lager, K.M., Janke, B.H., Kehrli, Jr., M.E., Roth, J.A. 2011. Enhanced pneumonia and disease in pigs vaccinated with an inactivated human-like (delta-cluster) H1N2 vaccine and challenged with pandemic 2009 H1N1 influenza virus. Vaccine. 29(15):2712-2719.

Immune responses elicited to a live-attenuated influenza virus vaccine compared to a traditional whole-inactivated virus vaccine for pandemic H1N1in pigs - (Abstract Only)

Loving, C.L., Vincent, A.L., Pena, L., Perez, D. 2011. Immune responses elicited to a live-attenuated influenza virus vaccine compared to a traditional whole-inactivated virus vaccine for pandemic H1N1 in pigs [abstract]. Keystone Symposium, Immunity in the Respiratory Tract. Poster No. 228. p. 163.

Innate immune responses to pathogens involved in the porcine respiratory disease complex - (Abstract Only)

Brockmeier, S.L., Loving, C.L., Vincent, A.L. 2011. Innate immune responses to pathogens involved in the porcine respiratory disease complex [abstract]. Keystone Symposia, Immunity in the Respiratory Tract. Poster No. 114. p. 149.

Innate Immune Responses are Enhanced in Pigs After Sequential Infection with Influenza Virus and Haemophilus parasuis - (Abstract Only)

Loving, C.L., Brockmeier, S.L., Vincent, A.L. 2010. Innate immune responses are enhanced in pigs after sequential infection with influenza virus and Haemophilus parasuis [abstract]. Conference of Research Workers in Animal Diseases. Paper No. 165.

G-CSF Analogue Treatment Increases Peripheral Neutrophil Numbers in Pigs - a Potential Alternative for In-Feed Antibiotics - (Abstract Only)

Loving, C.L., Brockmeier, S.L., Bayles, D.O., Greenlee, J.J., Lager, K.M., Kehrli, Jr., M.E. 2010. G-CSF analogue treatment increases peripheral neutrophil numbers in pigs - a potential alternative for in-feed antibiotics. Conference of Research Workers in Animal Diseases. Paper No. 140.

Comparison of Humoral and Cellular Immune Responses to Inactivated Swine Influenza Virus Vaccine in Weaned Pigs - (Abstract Only)

Platt, R., Gauger, P., Kimura, K., Roth, J., Vincent, A., Loving, C., Zanella, E., Lager, K., Kehrli, M. 2010. Comparison of humoral and cellular immune responses to inactivated swine influenza virus vaccine in weaned pigs [abstract]. Conference of Research Workers in Animal Diseases. Paper No. 085P/85P.

Use of an Avirulent Isolate of Haemophilus parasuis as a Vaccine - (Abstract Only)

Brockmeier, S., Register, K.B., Loving, C.L., Nicholson, T.L. 2010. Use of an avirulent Isolate of Haemophilus parasuis as a vaccine. 45th US-Japan Cooperative Program in Natural Resources Panel of Animal and Avian Health Meeting. p 14.

Safety and efficacy of a novel live attenuated influenza vaccine against pandemic H1N1 in swine - (Peer Reviewed Journal)

Pena, L., Vincent, A.L., Ye, J., Ciacci-Zanella, J.E., Angel, M., Lorusso, A., Gauger, P.C., Janke, B.H., Loving, C.L., Perez, D.R. 2011. Safety and efficacy of a novel live attenuated influenza vaccine against pandemic H1N1 in swine. Influenza and Other Respiratory Viruses. 5(S1):341-344.

Influenza Vaccination in the Face of Maternal Antibody Results in Enhanced Pneumonia Following Heterologous, Homosubtypic Influenza Challenge - (Abstract Only)

Loving, C.L., Brockmeier, S.L., Vincent, A.L., Gauger, P.C., Kehrli, Jr., M.E. 2010. Influenza vaccination in the face of maternal antibody results in enhanced pneumonia following heterologous, homosubtypic influenza challenge [abstract]. Keystone Symposia, Immunological Mechanisms of Vaccination. Paper No. 243.

Influenza Virus Coinfection with Bordetella bronchiseptica Enhances Bacterial Colonization and Host Responses Exacerbating Pulmonary Lesions - (Peer Reviewed Journal)

Loving, C.L., Brockmeier, S.L., Vincent, A.L., Palmer, M.V., Sacco, R.E., Nicholson, T.L. 2010. Influenza Virus Coinfection with Bordetella bronchiseptica Enhances Bacterial Colonization and Host Responses Exacerbating Pulmonary Lesions. Microbial Pathogenesis. 49(5):237-245.

Enhanced Pneumonia and Proinflammatory Cytokine Response in Pigs Challenged with Pandemic 2009 A/H1N1 Influenza Virus Following Vaccination with an Inactivated delta-Cluster H1N2 Virus - (Abstract Only)

Gauger, P.C., Vincent, A.L., Loving, C.L., Lager, K.M., Janke, B.A., Roth, J.A. 2010. Enhanced pneumonia and proinflammatory cytokine response in pigs challenged with pandemic 2009 A/H1N1 influenza virus following vaccination with an inactivated delta-cluster H1N2 virus [abstract]. International Conference on Emerging Infectious Diseases. Paper No. L1345.

Investigation of the Function of the Influenza A Virus PB1-F2 Protein During Infection of Swine and Human Cells with a Predominant Circulating Swine Virus Isolate - (Abstract Only)

Buehler, J., Mccullough, D., Loving, C.L., Vincent, A.L., Lager, K.M., Miller, C. 2010. Investigation of the Function of the Influenza A Virus PB1-F2 Protein During Infection of Swine and Human Cells with a Predominant Circulating Swine Virus Isolate [abstract]. American Society for Virology Meeting. p. 279.

Prior Swine Influenza Virus Infection Enhances Pulmonary Responses to Secondary Haemophilus parasuis Infection - (Proceedings)

Loving, C.L., Brockmeier, S., Vincent, A.L. 2010. Prior Swine Influenza Virus Infection Enhances Pulmonary Responses to Secondary Haemophilus parasuis Infection. In: Proceedings of the Pig Veterinary Society International Congress, July 18-21, 2010, Vancouver, Canada. p. 264.

Prior Colonization with an Avirulent Haemophilus parasuis Isolate Prevents Disease from a Subsequent Virulent Challenge with a Heterologous Isolate - (Proceedings)

Brockmeier, S., Loving, C.L., Mullins, M., Register, K.B., Nicholson, T.L. Prior Colonization with an Avirulent Haemophilus parasuis Isolate Prevents Disease from a Subsequent Virulent Challenge with a Heterologous Isolate. In: Proceedings of the Pig Veterinary Society International Congress, July 18-21, Vancouver, Canada. p. 192.

Enhanced Pneumonia With Pandemic 2009 A/H1N1 Swine Influenza Virus in Pigs - (Proceedings)

Gauger, P.C., Vincent, A.L., Loving, C.L., Lager, K.M. 2010. Enhanced Pneumonia With Pandemic 2009 A/H1N1 Swine Influenza Virus in Pigs. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 255.

Contribution of the Bordetella Bps Polysaccharide to Biofilm Formation and Respiratory Disease in Swine - (Abstract Only)

Nicholson, T.L., Brockmeier, S., Loving, C.L., Lu, H., Sloan, G.P., Deora, R. 2010. Contribution of the Bordetella Bps Polysaccharide to Biofilm Formation and Respiratory Disease in Swine [abstract]. American Society for Microbiology. p. 123.

Antecedent Influenza Virus Infection Enhances Pulmonary Responses to Secondary Haemophilus Infection in a Porcine Co-Infection Model - (Abstract Only)

Loving, C.L., Brockmeier, S.L., Vincent, A.L. 2010. Antecedent Influenza virus infection enhances pulmonary responses to secondary Haemophilus infection in a porcine co-infection model [abstract]. American Association of Immunologists. Paper No. 803219.

Swine influenza virus co-infection with Bordetella bronchiseptica enhances bacterial colonization and host immune responses exacerbating pulmonary lesions - (Abstract Only)

Loving, C.L., Brockmeier, S.L., Vincent, A.L., Palmer, M.V., Sacco, R.E., Nicholson, T.L. 2010. Swine influenza virus co-infection with Bordetella bronchiseptica enhances bacterial colonization and host immune responses exacerbating pulmonary lesions [abstract]. Conference Research Workers Disease Meeting. Paper No. 130.

Studies of pathogenesis, transmission, heterologous protection, and genomics of four isolates of Haemophilus parasuis - (Abstract Only)

Brockmeier, S., Loving, C.L., Register, K.B., Nicholson, T.L., Bayles, D.O., Phillips, G.J. 2009. Studies of pathogenesis, transmission, heterologous protection, and genomics of four isolates of Haemophilus parasuis [abstract]. 2009 Conference of Research Workers in Diseases. Abstract No. 15, p. 118.

Studies of Pathogenesis, Transmission, and Heterologous Protection of Four Isolates of Haemophilus parasuis in a Highly Susceptible Swine Population - (Abstract Only)

Brockmeier, S., Loving, C.L., Register, K.B., Nicholson, T.L., Bayles, D.O., Phillips, G.J. 2010. Studies of pathogenesis, transmission, and heterologous protection of four isolates of Haemophilus parasuis in a highly susceptible swine population [abstract]. 2010 American Association of Swine Veterinarians Annual Meeting. p. 127-129.

Characterization and comparative analysis of the genes encoding Haemophilus parasuis outer membrane proteins P2 and P5 - (Peer Reviewed Journal)

Mullins, M.A., Register, K.B., Bayles, D.O., Loving, C.L., Nicholson, T.L., Brockmeier, S.L., Dyer, D.W., Phillips, G.J. 2009. Characterization and Comparative Analysis of the Genes Encoding Haemophilus parasuis Outer Membrane Proteins P2 and P5. Journal of Bacteriology. 191(19):5988-6002.

Identification and Comparative Analysis of Genes Encoding Outer Membrane Proteins P2 and P5 in Haemophilus parsuis - (Abstract Only)

Mullins, M.A., Register, K.B., Bayles, D.O., Loving, C.L., Nicholson, T.L., Brockmeier, S.L., Dyer, D.W., Phillips, G.J. 2009. Identification and comparative analysis of genes encoding outer membrane proteins P2 and P5 in Haemophilus parsuis [abstract]. 109th American Society for Microbiology General Meeting. Poster No. Z-034.

Contribution of Bordetella bronchiseptica Filamentous Hemagglutinin and Pertactin to Respiratory Disease in Swine - (Peer Reviewed Journal)

Nicholson, T.L., Brockmeier, S., Loving, C.L. 2009. Contribution of Bordetella bronchiseptica Filamentous Hemagglutinin and Pertactin to Respiratory Disease in Swine. Infection and Immunity. 77(5):2136-2146.

Differences in immune response of pigs challenged with a high versus low dose inoculum of porcine reproductive and respiratory syndrome virus - (Peer Reviewed Journal)

Loving, C.L., Brockmeier, S.L., Vincent, A.L., Lager, K.M., Sacco, R.E. 2008. Differences in clinical disease and immune response of pigs challenged with a high-dose versus low-dose inoculum of porcine reproductive and respiratory syndrome virus. Viral Immunology. 21(3):315-325.

Investigating the porcine immune reponse to Haemophilus parasuis - (Abstract Only) - (15-May-08)

Early Induction of Cytokines in Pigs Coinfected with Swine Influenza Virus and Bordetella bronchiseptica - (Proceedings)

Brockmeier, S., Vincent, A.L., Loving, C.L., Nicholson, T.L., Sacco, R.E. 2008. Early Induction of Cytokines in Pigs Coinfected with Swine Influenza Virus and Bordetella bronchiseptica. In: Proceedings of the 20th International Pig Veterinary Society Congress, June 22-26, 2008, Durban, South Africa. 1:10.

Bordetella bronchiseptica Bvg Phase-Dependent Contribution to Colonization, Transmission, and Immune Responses in Pigs - (Abstract Only)

Loving, C.L., Nicholson, T.L., Brockmeier, S. 2008. Bordetella bronchiseptica Bvg Phase-Dependent Contribution to Colonization, Transmission, and Immune Responses in Pigs [abstract]. American Society for Microbiology Meeting, June 2-4, 2008, Boston, Massachusetts. 2008 CDROM.

Early Induction of Cytokines in Pigs Coinfected with Swine Influenza Virus and Bordetella bronchiseptica - (Abstract Only)

Brockmeier, S., Loving, C.L., Nicholson, T.L., Vincent, A.L., Sacco, R.E. 2008. Early Induction of Cytokines in Pigs Coinfected with Swine Influenza Virus and Bordetella bronchiseptica [abstract]. American Society for Microbiology Meeting, June 2-4, 2008, Boston, Massachusetts. 2008 CDROM.

Contribution of Bordetella bronchiseptica Filamentous Hemagglutinin and Pertactin to Respiratory Disease in Swine - (Abstract Only)

Nicholson, T.L., Brockmeier, S., Loving, C.L. 2008. Contribution of Bordetella bronchiseptica Filamentous Hemagglutinin and Pertactin to Respiratory Disease in Swine [abstract]. American Society for Microbiology Meeting, June 2-4, 2008, Boston, Massachusetts. 2008 CDROM.