Projects

INTERVENTION STRATEGIES TO CONTROL VIRAL DISEASES OF SWINE Appropriated (D)   Accession Number: 421208

Publications (Clicking on the reprint icon will take you to the publication reprint.)

A divergent picornavirus from a turkey with gastro-intestinal disease - (Peer Reviewed Journal)

Ng, T.F.F., Cheung, A.K., Wong, W., Lager, K.M., Kondov, N.O., Cha, Y., Murphy, D.A., Pogranichniy, R.M., Delwart, E. 2013. Divergent picornavirus from a turkey with gastro-intestinal disease. Genome Announcements. 1(3):e00134-13.

Functions of Rep and Rep' during porcine circovirus rolling-circle replication - (Abstract Only)

Cheung, A.K. 2013. Functions of Rep and Rep' during porcine circovirus rolling-circle replication [abstract]. DNA Replication and Recombination - training for proteins involved in eukaryotic DNA replication, Keystone Symposium, March 3-8, 2013, Banff, Canada. Paper No. Abs. x5 1017. p. 80.

Diversity of viruses detected by deep sequencing in pigs from a common background - (Peer Reviewed Journal)

Lager, K.M., Ng, T.F., Bayles, D.O., Alt, D.P., Delwart, E.L., Cheung, A.K. 2012. Diversity of viruses detected by deep sequencing in pigs from a common background. Journal of Veterinary Diagnostic Investigation. 24(6):1177-1179.

Replicative intermediates of porcine circovirus in animal tissue cultured cells or in bacteria undergoing copy-release replication - (Peer Reviewed Journal)

Cheung, A.K. 2012. Replicative intermediates of porcine circovirus in animal tissue cultured cells or in bacteria undergoing copy-release replication. Virology. 434(1):38-42.

Development of antinuclear antibodies and a genetic linkage in pigs infected with porcine circovirus type 2 - (Abstract Only)

Cheung, A.K., Kehrli, Jr., M.E., Lager, K.M., Gauger, P.C., Rohrer, G.A., Michael, D.D., Miller, L.C., Vincent, A.L., Braucher, D.R. 2012. Development of antinuclear antibodies and a genetic linkage in pigs infected with porcine circovirus type 2 [abstract]. IXth International Congress of Veterinary Virology. p. 189-190.

Porcine circovirus: transcription and rolling-circle DNA replication - (Review Article)

Cheung, A.K. 2012. Porcine circovirus: transcription and DNA replication. Virus Research. 164(1-2):46-53.

The RNA profile of porcine parvovirus 4, a Boca-like virus, is unique among the Parvoviruses - (Peer Reviewed Journal)

Cheung, A.K., Long, J.X., Huang, L., Yuan, S.S. 2011. The RNA profile of porcine parvovirus 4, a boca-like virus, is unique among the parvoviruses. Archives of Virology. 56(11):2071-2078.

Leukogram abnormalities in gnotobiotic pigs infected with porcine circovirus type 2 - (Peer Reviewed Journal)

Gauger, P.C., Lager, K.M., Vincent, A.L., Opriessnig, T., Cheung, A.K., Butler, J.E., Kehrli, Jr., M.E. 2011. Leukogram abnormalities in gnotobiotic pigs infected with porcine circovirus type 2. Veterinary Microbiology. 154(1-2):185-190.

Postweaning multisystemic wasting syndrome produced in gnotobiotic pigs following exposure to various amounts of porcine circovirus type 2a or type 2b - (Peer Reviewed Journal)

Gauger, P.C., Lager, K.M., Vincent, A.L., Opriessnig, T., Kehrli, Jr., M.E., Cheung, A.K. 2011. Postweaning multisystemic wasting syndrome produced in gnotobiotic pigs following exposure to various amounts of porcine circovirus type 2a or type 2b. Veterinary Microbiology. 153(3-4):229-239.

Porcine bocaviruses: genetic analysis and prevalence in Chinese swine population - (Peer Reviewed Journal)

Zhang, H.B., Huang, L., Lin, T., Sun, C.Q., Deng, Y., Wei, Z.Z., Cheung, A.K., Long, J.X., Yuan, S.S. 2011. Porcine bocaviruses: genetic analysis and prevalence in Chinese swine population. Epidemiology and Infection. 139(10):1581-1586.

Evidence for porcine parvovirus type 4 (PPV4) in Brazilian swine herds - (Proceedings)

Gava, D., Sa Rocha, C., Ritterbusch, G.A., Simon, N.L., Zanella, E.L., Caron, L., Cheung, A.K., Ciacci-Zanella, J.R. 2011. Evidence for porcine parvovirus type 4 (PPV4) in Brazilian swine herds. In: Proceedings of the 6th International Symposium on Emerging and Re-emerging Pig Diseases, June 12-15, 2011, Barcelona, Spain. p. 303.

Detection of a Novel Porcine Parvovirus in Chinese Swine Herds - (Peer Reviewed Journal)

Huang, L.V., Zhai, S.L, Cheung, A.K., Zhang, H.B., Long, J.X., Yuan, S.S. 2010. Detection of a novel porcine parvovirus, PPV4, in Chinese swine herds. Virology Journal. 7(1):333.

Identification of an Amino Acid Domain Encoded by the Capsid Protein Gene of Porcine Circovirus Type 2 that Modulates Viral Protein Distribution During Replication - (Peer Reviewed Journal)

Cheung, A.K., Greenlee, J.J. 2011. Identification of an amino acid domain encoded by the capsid gene of porcine circovirus type 2 that modulates intracellular viral protein distribution during replication. Virus Research. 155(1):358-362.

Discovery of Antinuclear Antibodies in Pigs Infected with Porcine Circovirus Type 2 - (Proceedings)

Kehrli, Jr., M.E., Gauger, P.C., Cheung, A.K., Vincent, A.L., Lager, K.M. 2010. Discovery of Antinuclear Antibodies in Pigs Infected with Porcine Circovirus Type 2. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 332.

The rolling-circle melting-pot model for porcine circovirus DNA replication - (Proceedings)

Cheung, A.K. 2009. Porcine Circovirus DNA Replication via the Rolling-Circle Mechanism. In: Proceedings of the Korean Society for Biochemistry and Molecular Biology (KSBMB) 66th Annual Meeting, May 12, 2009, Seoul, Republic of Korea. Paper No. S8-1. p. 154.

Homologous recombination within the capsid gene of porcine circovirus type 2 subgroup viruses via natural co-infection - (Peer Reviewed Journal)

Cheung, A.K. 2009. Homologous Recombination within the Capsid Gene of Porcine Circovirus Type 2 Subgroup Viruses via Natural Co-Infection. Archives of Virology. 154(3):531–534.

Analysis of the biologic differences between porcine circovirus type 2 Group-1 and Group-2 viruses - (Abstract Only)

Cheung, A.K. 2008. Analysis of the Biologic Differences Between Porcine Circovirus Type 2 Group-1 and Group-2 Viruses [abstract]. International Congress of Virology. Paper No. VOP-52. p. 37.

Determination of growth stimulating activity of 'Rhizoginin-S' on cell cultures used in virology - (Abstract Only)

Bitov, N., Nahanov, A., Sembaev, K., Gilmanov, M., Cheung, A.K. 2008. Determination of growth stimulating activity of 'Rhizoginin-S' on cell cultures used in virology [abstract]. FEBS Journal 275(Suppl. 1):402. Abstract No. PP8-64.

Pathogenesis of PCV2a and PCV2b virus in germ-free pigs - (Proceedings)

Gauger, P.C., Lager, K.M., Vincent, A.L., Opriessnig, T., Kehrli, Jr., M.E., Cheung, A.K. 2008. Pathogenesis of PCV2a and PCV2b Virus in Germ-Free pigs. In: Proceedings of the International Pig Veterinary Society Congress, June 22-26, 2008, Durban, South Africa. Paper No. OR.01.28.

Reproduction of PMWS of high mortality with a porcine circovirus type 2-group 1 isolate - (Proceedings)

Cheung, A.K., Lager, K.M., Gauger, P.C., Vincent, A.L., Opriessnig, T., Kehrli, Jr., M.E. 2007. Reproduction of PMWS of high mortality with a porcine circovirus type 2-group 1 isolate. In: Proceedings of the 13th International World Association of Veterinary Laboratory Diagnosticians Symposium, November 11-14, 2007, Melbourne, Australia. p. 213.

Comparison of the pathogenicity of porcine circovirus type 2 group 1 and group 2 isolates - (Proceedings)

Cheung, A.K., Lager, K.M., Gauger, P.C., Vincent, A.L., Opriessnig, T. 2007. Comparison of the pathogenicity of porcine circovirus type 2 group 1 and group 2 isolates. In: Proceedings of the 5th International Symposium on Emerging and Re-Emerging Pig Diseases, June 24-27, 2007, Krakow, Poland. p. 273.

Mortality in pigs given PCV2 virus derived from DNA clones - (Peer Reviewed Journal)

Lager, K.M., Gauger, P.C., Vincent, A.L., Opriessnig, T., Kehrli, Jr., M.E., Cheung, A.K. 2007. Mortality in pigs given porcine circovirus type 2 subgroup 1 and 2 viruses derived from DNA clones. Veterinary Record. 161(12):428-429.

Exploring the genetic basis for porcine circovirus pathogenicity - (Abstract Only)

Cheung, A.K. 2007. Exploring the genetic basis for porcine circovirus pathogenicity [abstract]. 5th International Geminivirus Symposium and 3rd International ssDNA Comparative Virology Workshop. Paper No. Py4-KN. p. 122.

Characterization of the leukogram in PCV2 infected germ-free pigs - (Proceedings)

Gauger, P.C., Lager, K.M., Cheung, A.K. 2007. Characterization of the leukogram in PCV2 infected germ-free pigs. In: Proceedings of the 46th Annual North Central Conference of Veterinary Laboratory Diagnosticians, June 7-8, 2007, Ames, Iowa. p. 39-42.

Homologous recombination plays minor role in excision of unit-length viral genomes from head-to-tail direct tandem repeats of porcine circovirus during DNA replication in Escherichia coli - (Peer Reviewed Journal)

Cheung, A.K. 2007. Homologous recombination plays minor role in excision of unit-length viral genomes from head-to-tail direct tandem repeats of porcine circovirus during DNA replication in Escherichia coli. Archives of Virology. 152:1531-1539.

PCVAD diagnosis and emerging diseases: building a systematic approach - (Proceedings)

Lager, K.M., Gauger, P.C., Vincent, A.L., Cheung, A.K. 2007. PCVAD diagnosis and emerging diseases: building a systematic approach. In: Proceedings of the American Association of Swine Veterinarians Annual Meeting, March 3-6, 2007, Orlando, Florida. p. 525-528.

A stem-loop structure, sequence non-specific, at the origin of DNA replication of porcine circovirus is essential for termination but not for initiation of rolling-circle DNA replication - (Peer Reviewed Journal)

Cheung, A.K. 2007. A stem-loop structure, sequence non-specific, at the origin of DNA replication of porcine circovirus is essential for termination but not for initiation of rolling-circle DNA replication. Virology. 363(1):229-235.

Identification of two genotype subgroups of porcine circovirus type 2 in swine herds of the United States - (Abstract Only)

Cheung, A.K., Lager, K.M., Vincent, A.L. 2006. Identification of two genotype subgroups of porcine circovirus type 2 in swine herds of the United States [abstract]. Conference of Research Workers in Animal Diseases 87th Annual Meeting. Paper No. 171. p. 78.

Detection of two porcine circovirus type 2 genotypic groups in United States swine herds - (Peer Reviewed Journal)

Cheung, A.K., Lager, K.M., Kohutyuk, O.I., Vincent, A.L., Henry, S.C., Baker, R.B., Rowland, R.R., Dunham, A.G. 2007. Detection of two porcine circovirus type 2 genotypic groups in United States swine herds. Archives of Virology. 152(5):1035-1044.

Diagnostics of Severe PCVAD - (Proceedings)

Lager, K.M., Vincent, A.L., Cheung, A.K., Gauger, P.C. 2006. Diagnostics of severe PCVAD. In: Proceedings of the 14th Annual Swine Disease conference for Practitioners, November 9-10, 2006, Ames, Iowa. p. 131-133.

ROLLING-CIRCLE REPLICATION OF AN ANIMAL CIRCOVIRUS GENOME IN A THETA-REPLICATING BACTERIAL PLASMID IN ESCHERICHIA COLI - (Abstract Only)

Cheung, A.K. 2006. Rolling-circle replication of an animal circovirus genome in a theta-replicating bacterial plasmid in Escherichia coli [abstract]. 7th International Congress of European Society for Veterinary Virology. Paper No. 049.

ROLLING-CIRCLE REPLICATION OF AN ANIMAL CIRCOVIRUS GENOME IN A THETA-REPLICATING BACTERIAL PLASMID IN ESCHERICHIA COLI - (Peer Reviewed Journal)

Cheung, A.K. 2006. Rolling-circle replication of an animal circovirus genome in a Theta-replicating bacterial plasmid in Escherichia coli. Journal of Virology. 80(17):8686-8694.

REGENERATION OF THE REPLICATION-ASSOCIATED PROTEINS TANDEM DIRECT REPEAT RECOGNITION NUCLEOTIDE SEQUENCE AT THE ORIGIN OF DNA REPLICATION OF PORCINE CIRCOVIRUS TYPE 1 - (Peer Reviewed Journal)

Cheung, A.K. 2005. Regeneration of the replication-associated proteins tandem direct repeat recognition nucleotide sequence at the origin of DNA replication of porcine circovirus type 1. Virology. 346(1):32-39.

INVESTIGATION OF THE TANDEM DIRECT REPEATS AT THE ORIGIN OF DNA REPLICATION OF PORCINE CIRCOVIRUS TYPE 1 - (Abstract Only)

Cheung, A.K. 2005. Investigation of the tandem direct repeats at the origin of DNA replication of porcine circovirus type 1 [abstract]. International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology. Paper No. 12. p. 43.

MUTATIONAL ANALYSIS OF THE TANDEM DIRECT REPEATS AT THE ORI OF PORCINE CIRCOVIRUS - (Abstract Only)

Cheung, A.K. 2005. Mutational analysis of the tandem direct repeats at the Ori of porcine circovirus [abstract]. International Congress of Virology. p. 79-80.

MUTATIONAL ANALYSIS OF THE DIRECT TANDEM REPEAT SEQUENCES AT THE ORIGIN OF DNA REPLICATION OF PORCINE CIRCOVIRUS TYPE 1 - (Peer Reviewed Journal)

Cheung, A.K. 2005. Mutational analysis of the direct tandem repeat sequences at the origin of DNA replication of porcine circovirus type 1. Virology. 339:192-199.

DETECTION OF RAMPANT NUCLEOTIDE REVERSION AT THE ORIGIN OF DNA REPLICATION OF PORCINE CIRCOVIRUS TYPE 1 - (Peer Reviewed Journal)

Cheung, A.K. 2005. Detection of rampant nucleotide reversion at the origin of DNA replication of porcine circovirus type 1. Virology. 333(1):22-30.

PALINDROME REGENERATION BY TEMPLATE-STRAND SWITCHING MECHANISM AT THE ORIGIN OF DNA REPLICATION OF PORCINE CIRCOVIRUS VIA THE ROLLING-CIRCLE MELTING-POT REPLICATION MODEL - (Peer Reviewed Journal)

Cheung, A.K. 2004. Palindrome regeneration by template strand switching mechanism at the origin of DNA replication of porcine circovirus via the rolling circle melting pot replication model. Journal of Virology. 78(17):9016-9029.

IDENTIFICATION OF AN OCTANUCLEOTIDE MOTIF SEQUENCE AT THE ORIGIN OF DNA REPLICATION OF PORCINE CIRCOVIRUS TYPE 2 ESSENTIAL FOR VIRAL PROTEIN, DNA AND PROGENY VIRUS BIOSYNTHESIS - (Peer Reviewed Journal)

Cheung, A.K. 2004. Identification of an octanucleotide motif sequence essential for viral protein, DNA, and progeny virus biosynthesis at the origin of DNA replication of porcine circovirus type 2. Virology. 324(1):28-36.

DETECTION OF TEMPLATE STRAND-SWITCHING DURING INITIATION AND TERMINATION OF DNA REPLICATION OF PORCINE CIRCOVIRUS - (Peer Reviewed Journal)

Cheung, A.K. 2004. Detection of template strand-switching during initiation and termination of dna replication of porcine circovirus. Journal of Virology. 78(8):4268-4277.

A NOVEL ROLLING-CIRCLE DNA REPLICATION MECHANISM FOR PORCINE CIRCOVIRUS - (Abstract Only)

Cheung, A.K. 2004. A novel rolling-circle DNA replication mechanism for porcine circovirus. 2nd International ssDNA Comparative Virology Workshop. Paper No. 17/2 S2-4.

IDENTIFICATION OF THE ESSENTIAL AND NON-ESSENTIAL TRANSCRIPTION UNITS FOR PROTEIN SYNTHESIS, DNA REPLICATION AND INFECTIOUS VIRUS PRODUCTION OF PORCINE CIRCOVIRUS TYPE 1 - (Peer Reviewed Journal)

Cheung, A.K. 2004. Identification of the essential and non-essential transcription units for protein synthesis, DNA replication and infectious virus production of porcine circovirus type 1. Archives of Virology. 149(5):975-988.

IDENTIFICATION OF THE ESSENTIAL AND NON-ESSENTIAL RNAS FOR VIRAL PROTEIN SYNTHESIS AND DNA REPLICATION OF PORCINE CIRCOVIRUS TYPE 2 - (Proceedings) - (24-Apr-03)

THE ESSENTIAL AND NON-ESSENTIAL TRANSCRIPTION UNITS FOR VIRAL PROTEIN SYNTHESIS AND DNA REPLICATION OF PORCINE CIRCOVIRUS TYPE 2 - (Peer Reviewed Journal)

CHEUNG, A.K. THE ESSENTIAL AND NON-ESSENTIAL TRANSCRIPTION UNITS FOR VIRAL PROTEIN SYNTHESIS AND DNA REPLICATION OF PORCINE CIRCOVIRUS TYPE 2. VIROLOGY. 2003. v. 313. p. 452-459.

Comparative analysis of the transcriptional patterns of pathogenic and nonpathogenic porcine circoviruses - (Peer Reviewed Journal)

Cheung, A.K. 2003. Comparative analysis of the transcriptional patterns of pathogenic and nonpathogenic porcine circoviruses. Virology. 310(1):41-49.

TRANSCRIPTIONAL ANALYSIS OF PORCINE CIRCOVIRUS TYPE 2 - (Peer Reviewed Journal)

Cheung, A.K. 2003. Transcriptional analysis of porcine circovirus type 2. Virology. 305(1):168-80.

TRANSCRIPTIONAL ANALYSIS OF PORCINE CIRCOVIRUSES - (Abstract Only) - (27-Jul-02)

KINETICS OF TYPE 2 PORCINE CIRCOVIRUS REPLICATION - (Proceedings) - (01-Jun-01)

INDUCTION OF APOPTOSIS IN MADIN-DARBY BOVINE KIDNEY CELLS BY PSEUDORABIES VIRUS - (Abstract Only) - (08-Nov-98)

ANALYSIS OF THE LATENCY-ASSOCIATED TRANSCRIPT/UL1-3.5 GENE CLUSTER PROMOTER COMPLEX OF PSEUDORABIES VIRUS - (Peer Reviewed Journal) - (10-Sep-98)

ANALYSIS OF THE LATENCY-ASSOCIATED TRANSCRIPT/UL1.3-5 GENE CLUSTER PROMOTER COMPLEX OF PESUDORABIES VIRUS - (Abstract Only) - (01-Aug-98)

KINETICS OF GENE EXPRESSION AND REPLICATION OF PSEUDORABIES VIRUS DURING VARIOUS STAGES OF MDBK AND 3T3 CELL CYCLES - (Abstract Only) - (27-Mar-98)

HERPES SIMPLEX VIRUS TYPE 1 ICP-0 INDUCES REACTIVATION OF PSEUDORABIES VIRUS FROM LATENTLY INFECTED TRIGEMINAL GANGLIA EXPLANT CULTURES - (Peer Reviewed Journal) - (15-Oct-97)

REACTIVATION OF PSEUDORABIES VIRUS FROM LATENTLY INFECTED TRIGEMINAL GANGLIA OF SWINE BY HERPES SIMPLEX VIRUS TYPE 1 ICP-0 - (Abstract Only) - (02-Aug-97)

HERPES SIMPLEX VIRUS TYPE 1 ICP-0 REACTIVATES PSEUDORABIES VIRUS FROM LATENCY-INFECTED TRIGEMINAL GANGLIA - (Abstract Only) - (02-May-97)

REPLICATION AND PATHOGENICITY AFTER INTRANASAL AND INTRACRANIAL INOCULATIONOF SWINE WITH A RECOMBINANT PSEUDORABIES VIRUS CONTAINING A DELETION AT THEUL/IR JUNCTION - (Peer Reviewed Journal) - (31-May-96)

NEW GENE TARGETS FOR ENGINEERING PSEUDORABIES VIRUS VACCINES - (Peer Reviewed Journal) - (15-Feb-96)

PSEUDORABIES VIRUS EP0 IS FUNCTIONALLY HOMOLOGOUS TO VARICELLA-ZOSTER VIRUS ORF61 PROTEIN AND HERPES SIMPLEX VIRUS TYPE 1 ICP0 - (Peer Reviewed Journal) - (01-Jun-95)

A DELETION AT THE UL/IR JUNCTION REDUCES PSEUDORABIES VIRUS NEUROVIRULENCE - (Peer Reviewed Journal) - (17-Nov-94)