Publications (Clicking on the reprint icon will take you to the publication reprint.)

Regulation of gene expression in human mammary epithelium: effect of breast pumping - (Peer Reviewed Journal)

Maningat, P.D., Sen, P., Sunehag, A.L., Hadsell, D.L., Haymond, M.W. 2007. Regulation of gene expression in human mammary epithelium: Effect of breast pumping. Journal of Endocrinology. 195(3):503-511.

The declining phase of lactation: Peripheral or central, programmed or pathological? - (Review Article)

Hadsell, D., George, J., Torres, D. 2007. The declining phase of lactation: Peripheral or central, programmed or pathological? Journal of Mammary Gland Biology and Neoplasia. 12:59-70.

Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2 - (Review Article)

Dearth, R.K., Cui, X., Kim, H., Kuiatse, I., Lawrence, N.A., Zhang, X., Divisova, J., Britton, O.L., Mohsin, S., Allred, D.C., Hadsell, D.L., Lee, A.V. 2006. Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2. Molecular and Cellular Biology. 26:9302-9314.

GLP-2 rapidly activates divergent intracellular signaling pathways involved in intestinal cell survival and proliferation in neonatal piglets - (Peer Reviewed Journal)

Burrin, D.G., Stoll, B., Guan, X., Cui, L., Chang, X., Hadsell, D. 2007. GLP-2 rapidly activates divergent intracellular signaling pathways involved in intestinal cell survival and proliferation in neonatal piglets. American Journal of Physiology - Endocrinology and Metabolism. 292:E281-E291

The growth hormone receptor antagonist pegvisomant blocks both mammary gland development and MCF-7 breast cancer xenograft growth. - (Peer Reviewed Journal)

Divisova, J., Kuiatse, I., Lazard, Z., Weiss, H., Vreeland, F., Hadsell, D.L., Schiff, R., Osborne, C.K., Lee, A.V. 2006. The growth hormone receptor antagonist pegvisomant blocks both mammary gland development and MCF-7 breast cancer xenograft growth. Breast Cancer Research and Treatment. 98(3):315-327.

Overexpression of des(1-3)hIGF-I in the mammary gland during prolonged lactation enhances milk yield and elevates prolactin secretion - (Abstract Only)

Hadsell, D.L., Torres, D., George, J., Shelton, G.S., Parlow, A.F., Fiorotto, M.L. 2005. Overexpression of des(1-3)hIGF-I in the mammary gland during prolonged lactation enhances milk yield and elevates prolactin secretion [abstract]. In: The 87th Annual Meeting of the Endocrine Society, June 4-7, 2005, San Diego, California. p. 531.

CHANGES IN SECRETORY CELL TURNOVER, AND MITOCHONDRIAL OXIDATIVE DAMAGE IN THE MOUSE MAMMARY GLAND DURING A SINGLE PROLONGED LACTATION CYCLE SUGGEST THE POSSIBILITY OF ACCELERATED CELLULAR AGING. - (Peer Reviewed Journal)

Hadsell, D.L., Torres, D., George, J., Capuco, A.V., Ellis, S.E., Fiorotto, M.L. 2006. Changes in secretory cell turnover, and mitochondrial oxidative damage in the mouse mammary gland during a single prolonged lactation cycle suggest the possibility of accelerated cellular aging. Experimental Gerontology. 41(3):271-281.

Lactation persistence is enhanced in transgenic mice overexpressing des(1-3)hIGF-I in the mammary gland - (Abstract Only)

Hadsell, D.L., Torres, D.T., George, J., Shelton, G.S., Fiorotto, M.L. 2004. Lactation persistence is enhanced in transgenic mice overexpressing des(1-3)hIGF-I in the mammary gland [abstract]. Journal of Animal Science Supplement. 82(Suppl. 1):204.

Estrogen-mediated down-regulation of E-cadherin in breast cancer cells - (Peer Reviewed Journal)

Oesterreich, S., Deng, W., Jiang, S., Cui, X., Ivanova, M., Schiff, R., Kang, K., Hadsell, D.L., Behrens, J., Lee, A.V. 2003. Estrogen-mediated down-regulation of E-cadherin in breast cancer cells. Cancer Research. 63:5203-5208.

The insulin-like growth factor system in normal mammary gland function - (Review Article)

Hadsell, D. 2003. The insulin-like growth factor system in normal mammary gland function. Breast Disease. 17:3-14.

COOPERATIVE INTERACTION BETWEEN MUTANT P53 AND DES(1-3)IGF-I ACCELERATES MAMMARY TUMORIGENESIS IN BIGENIC MICE - (Peer Reviewed Journal) - (02-Dec-99)

ACTIVITY OF UPSTREAM STIMULATORY FACTOR (USF) DURING MAMMARY GLAND DEVELOPMENT AND MILK PROTEIN GENE EXPRESSION. - (Abstract Only) - (20-Mar-98)

REGULATION OF CELL APOPTOSIS BY INSULIN-LIKE GROWTH FACTOR I. - (Book / Chapter) - (01-Dec-97)

MAMMARY-SPECIFIC TRANSGENES AS TOOLS IN SCIENCE AND INDUSTRY. - (Review Article) - (15-Jun-97)