Projects

MACRO- AND MICRONUTRIENT MODULATION OF BIOMARKERS OF CHRONIC DISEASE AND INDICATORS OF NUTRITIONAL ADEQUACY Appropriated (D)   Accession Number: 415241

BIOAVAILABILITY AND HEALTH BENEFITS OF PHYTONUTRIENTS Appropriated (D)   Accession Number: 415242

PHYSICAL ACTIVITY TO FUEL MANAGEMENT AND GLUCOSE REGULATION Nonfunded Cooperative Agreement (N)   Accession Number: 415225

NATURALLY OCCURRING FOOD COMPONENTS AND THEIR MODULATION OF CANCER RISK Reimbursable (R)   Accession Number: 423117

THE HUMAN MICROBIOME AND FLAVONOID ABSORPTION IMPLICATIONS FOR CANCER RISK Reimbursable (R)   Accession Number: 423360

THE INFLUENCE OF LOW CALORIES CRANBERRY JUICE ON RISK FACTORS FOR CARDIOVASCULAR DISEASE Reimbursable (R)   Accession Number: 418951

NUTRITION RESEARCH TO REDUCE RISK OF DISEASE Specific Cooperative Agreement (S)   Accession Number: 422008

Nutrition Research To Reduce the Risk of Disease Specific Cooperative Agreement (S)   Accession Number: 423933

NUTRITION RESEARCH OF NATURALLY OCCURRING FOOD COMPONENTS TO REDUCE RISK OF CANCER Specific Cooperative Agreement (S)   Accession Number: 423053

HIGH OLEIC ACID AND VASCULAR HEALTH Trust (T)   Accession Number: 422081

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Anthocyanins and heart disease - (Book / Chapter)

Novotny Dura, J. 2012. Anthocyanins and heart disease. In: Carkeet, C., Grann, K., Randolph, R.K., Venzon, D.S., Izzy, S. Phytochemicals: Health Promotion and Therapeutic Potential. Boca Raton, FL: Taylor and Francis CRC Press. p. 559-568.

Anthocyanin bioavailability: Past progress and current challenges - (Book / Chapter)

Novotny Dura, J. 2012. Anthocyanin bioavailability: Past progress and current challenges. In: Patil B.S., Jayaprakasha G.K., Chidambara Murthy K.N., Seeram, N.P. Emerging Trends in Dietary Components for Preventing and Combating Disease. Washington, DC: American Chemical Society. p.559-568.

An HPLC-MS method for d8-ß-carotene and d4-retinyl esters useful in studies of ß-carotene absorption and its conversion to vitamin A in humans - (Peer Reviewed Journal)

Fleshman, M.K., Riedl, K., Novotny Dura, J., Schwartz, S.J., Harrison, E.H. 2012. An HPLC-MS method for d8-ß-carotene and d4-retinyl esters useful in studies of ß-carotene absorption and its conversion to vitamin A in humans. Journal of Lipid Research. 53:820-827.

Anthocyanin kinetics are dependent on anthocyanin structure - (Peer Reviewed Journal)

Novotny Dura, J., Clevidence, B.A., Kurilich, A.C. 2011. Anthocyanin kinetics are dependent on anthocyanin structure. British Journal of Nutrition. 107:504-509.

The measured energy value of pistachio nuts in the human diet - (Peer Reviewed Journal)

Baer, D.J., Gebauer, S.K., Novotny Dura, J. 2011. The measured energy value of pistachio nuts in the human diet. British Journal of Nutrition. 28:1-6.

Molybdenum nutriture in humans - (Peer Reviewed Journal)

Novotny Dura, J. 2011. Molybdenum nutriture in humans. Evidence-based Complementary and Alternative Medicine. 16(3):164-168.

Oolong tea does not improve glucose metabolism in non-diabetic adults - (Peer Reviewed Journal)

Baer, D.J., Novotny Dura, J., Harris, K., Stote, K., Clevidence, B.A., Rumpler, W.V. 2010. Oolong tea does not improve glucose metabolism in non-diabetic adults. European Journal of Clinical Nutrition. 65:87-93.

Beta-carotene conversion to vitamin A decreases as the dietary dose increases in humans - (Peer Reviewed Journal)

Novotny Dura, J., Harrison, D.J., Pawlosky, R., Flanagan, V.P., Harrison, E.H., Kurilich, A.C. 2010. Beta-Carotene conversion to vitamin A decreases as the dietary dose increases in humans. Journal of Nutrition. 140(5):915-918.

Vitamin K absorption and kinetics in human subjects after consumption of 13C-labeled phylloquinone from kale - (Peer Reviewed Journal)

Novotny Dura, J., Kurilich, A.C., Britz, S.J., Baer, D.J., Clevidence, B.A. 2010. Vitamin K absorption and kinetics in human subjects after consumption of 13C-labeled phylloquinone from kale. British Journal of Nutrition. 104(6):858-62.

Bioavailability of Anthocyanins from Purple Carrot Juice: Effects of Acylation and Plant Matrix - (Peer Reviewed Journal)

Charron, C.S., Kurilich, A.C., Clevidence, B.A., Simon, P.W., Harrison, D.J., Britz, S.J., Baer, D.J., Novotny Dura, J. 2009. Bioavailability of Anthocyanins from Purple Carrot Juice: Effects of Acylation and Plant Matrix. Journal of Agricultural and Food Chemistry. 57(4):1226-1230.

Isotopic Labeling of Red Cabbage Anthocyanins with Atmospheric 13-CO2 - (Peer Reviewed Journal)

Charron, C.S., Britz, S.J., Mirecki, R.M., Harrison, D.J., Clevidence, B.A., Novotny, J. 2008. Isotopic labeling of red cabbage anthocyanins with atmospheric 13-CO2. J. Amer. Soc. Hort. Sci. 133(3):351-359.

Anthocyanin excretion increases linearly with increasing strawberry dose. - (Peer Reviewed Journal)

Carkeet, C., Clevidence, B.A., Novotny, J. 2008. Anthocyanin excretion by humans increases linearly with increasing strawberry dose. Journal of Nutrition. 138(5):897-902.

Role of Color and Pigments in Breeding, Genetics, and Nutritional Improvement of Carrots - (Book / Chapter)

Simon, P.W., Tanumihardjo, S.A., Clevidence, B.A., Novotny Dura, J. 2008. Role of Color and Pigments in Breeding, Genetics, and Nutritional Improvement of Carrots. In: Culver, C.A., Wrolstad, R.E., editors. Color Quality of Fresh and Processed Foods. Washington, D.C.: Oxford University Press. p. 151-165.

EFFECTS OF ANTHOCYANIN AND CAROTENOID COMBINATIONS ON FOLIAGE AND IMMATURE FRUIT COLOR OF CAPSICUM ANNUM L. - (Peer Reviewed Journal)

Lightbourn, G., Griesbach, R., Novotny Dura, J., Clevidence, B.A., Rao, D.D., Stommel, J.R. 2008. Effects of anthocyanin and carotenoid combinations on foliage and immature fruit color of capsicum annum l. Journal of Heredity. 99:105-111.

Anthocyanins Present in Some Tropical Fruits. - (Peer Reviewed Journal)

Brito, E., Araujo, M., Alves, R., Clevidence, B.A., Novotny Dura, J. 2007. Anthocyanins present in some tropical fruits. Journal of Agricultural and Food Chemistry. 55:9389-9394.

Dynamic Modeling of Molybdenum Metabolism in Humans - (Book / Chapter)

Novotny Dura, J., Turnlund, J.R. 2007. Dynamic Modeling of Molybdenum Metabolism in Humans. Virginia: Virginia Polytechnic University. p. 39-50.

The Effect of Dose Size on Bioavailability of Acylated and Nonacylated Anthocyanins from Red Cabbage (Brassica oleracea L. var. capitata) - (Peer Reviewed Journal)

Charron, C.S., Clevidence, B.A., Britz, S.J., Novotny Dura, J. 2007. The effect of dose size on bioavailability of acylated and nonacylated anthocyanins from red cabbage (Brassica oleracea L. var. capitata). Journal of Agricultural and Food Chemistry. 55(13):5354-5362.

The Effect of Dose Size on Bioavailability of Acylated and Nonacylated Anthocyanins from Red Cabbage - (Abstract Only)

Charron, C.S., Clevidence, B.A., Britz, S.J., Novotny Dura, J. 2007. The Effect of Dose Size on Bioavailability of Acylated and Nonacylated Anthocyanins from Red Cabbage [abstract]. Experimental Biology. p. 240.7.

A feasibiity study to quantify in vivo human alpha-tocopherol metabolism - (Peer Reviewed Journal)

Clifford, A.J., De Moura, F.F., Ho, C.C., Chuang, J.C., Follett, J.R., Fadel, J.G., Novotny Dura, J. 2006. A feasibiity study to quantify in vivo human alpha-tocopherol metabolism. American Journal of Clinical Nutrition. 84(6):1430-1441.

A FEASIBILITY STUDY TO QUANTIFY IN VIVO HUMAN ALPHA-TOCOPHEROL METABOLISM - (Peer Reviewed Journal)

Clifford, A.J., Demoura, F.F., Ho, C.C., Chuang, J.C., Follett, J., Fadel, J.G., Vogel, J.S., Novotny Dura, J., Cohn, W. 2006. A feasibility study to quantify in vivo human alpha-tocopherol metabolism. American Journal of Clinical Nutrition. 84(6):1430-1441.

MOLYBDENUM INTAKE INFLUENCES MOLYBDENUM KINETICS IN HUMANS. - (Peer Reviewed Journal)

Novotny Dura, J., Turnlund, J.R. 2007. Molybdenum intake influences molybdenum kinetics in humans. Journal of Nutrition. 137:37-42.

STABILITY OF URINARY METABOLITES OF STRAWBERRY ANTHOCYANINS - (Abstract Only)

Carkeet, C., Clevidence, B.A., Novotny Dura, J. 2006. Stability of urinary metabolites of strawberry anthocyanins. Federation of American Societies for Experimental Biology Conference.

MOLYBDENUM DISPOSITION IN HUMANS DURING MOLYBDENUM DEPLETION AND REPLETION. - (Peer Reviewed Journal)

Novotny Dura, J., Turnlund, J.R. 2006. Molybdenum disposition in humans during molybdenum depletion and repletion. Journal of Nutrition 136:953-957.

EFFECT OF COOKING METHOD ON XANTHOPHYLL CONTENT OF YELLOW-FLESHED POTATO - (Proceedings)

Clevidence, B.A., Haynes, K.G., Rao, D.D., Novotny Dura, J. 2005. Effect of cooking method on xanthophyll content of yellow-fleshed potato. United States Japan Natural Resources Protein Panel. 34:280-284.

WHAT CAN PHARMACOKINETIC MODELS TELL US ABOUT THE DISPOSITION OF LYCOPENE AND THE POTENTIAL ROLE OF LYCOPENE IN CANCER PREVENTION? - (Proceedings)

Novotny Dura, J. 2005. What can pharmacokinetic models tell us about the disposition of lycopene and the potential role of lycopene in cancer prevention? Journal of Nutrition 135:2048S-2049S.

PLASMA AND URINE RESPONSES ARE LOWER FOR ACYLATED VS NONACYLATED ANTHOCYANINS FROM RAW AND COOKED PURPLE CARROT. - (Peer Reviewed Journal)

Kurilich, A.C., Clevidence, B.A., Britz, S.J., Simon, P.W., Novotny Dura, J. 2005. Plasma and urine responses are lower for acylated vs nonacylated anthocyanins from raw and cooked purple carrot. Journal of Agricultural and Food Chemistry. 53:6537-6542.

PLASMA APPERANCE OF LABELED BETA-CAROTENE, LUTEIN, AND RETINOL IN HUMANS AFTER CONSUMPTION OF ISOTOPICALLY LABELED-KALE - (Peer Reviewed Journal)

Novotny Dura, J., Kurilich, A.C., Britz, S.J., Clevidence, B.A. 2005. Plasma appearance of labeled beta-carotene, lutein, and retinol in human consumption of iso topically-labeled kale. Available online: http://pubs.acs.org/cgi-bin/asap.cgi/jafcau/asap/html/jf050570o.html.

BIOAVAILABILITY OF ANTHOCYANINS FROM RAW AND COOKED PURPLE CARROTS. - (Proceedings)

Clevidence, B.A., Kurilich, A.C., Britz, S., Simon, P.W., Novotny Dura, J. 2004. Bioavailability of anthocyanins from raw and cooked purple carrots. Proceedings of the 33rd U.S.-Japan Cooperative Program in Natural Resources. UJNR 33:171-174.

MATHEMATICAL INVESTIGATIONS OF CAROTENOID KINETICS IN HUMANS. - (Book / Chapter)

Novotny Dura, J. 2005. Mathematical investigations of carotenoid kinetics in humans. Mathematical Modeling in Health and Toxicology. Athens, GA: Mathematical Biology Press. 189-204.

APPEARANCE OF LABELED BETA-CAROTENE, LUTEIN, RETINOL, AND PHYLLOQUINONE IN PLASMA AFTER CONSUMPTION OF ISOTOPICALLY-LABELED KALE. - (Abstract Only)

Novotny Dura, J., Kurilich, A.C., Britz, S.J., Baer, D.J., Clevidence, B.A. 2004. Appearance of labeled beta-carotene, lutein, retinol, and phylloquinone in plasma after consumption of isotopically-labeled kale. Journal of Lipid Research 46:1896-903

COMPARTMENTAL MODELING OF 14C-LYCOPENE IN THE F344 RAT - (Abstract Only)

Novotny Dura, J., Zaripheh, S., Erdman, J. 2004. Compartmental modeling of 14c-lycopene in the f344 rat. Experimental Biology.

LABELED BETA-CAROTENE AND LUTEIN IN PLASMA AFTER CONSUMPTION OF ISOTOPICALLY-LABELED KALE - (Abstract Only)

Novotny Dura, J., Kurilich, A.C., Britz, S.J., Clevidence, B.A. 2004. Labeled beta-carotene and lutein in plasma after consumption of isotopically-labeled kale. Carotenoid Gordon Conference.

ESSENTIAL FEATURES OF PHYTONUTRIENT KINETIC STUDIES. - (Abstract Only)

Novotny Dura, J. 2003. Essential features of phytonutrient kinetic studies.. Meeting Abstract.

INTERACTIONS BETWEEN GENDER AND FOOD INTAKE ON THE RELATIONSHIP BETWEEN ENERGY EXPENDITURE AND BODY COMPOSITION. - (Peer Reviewed Journal)

Paul, D.R., Novotny Dura, J., Rumpler, W.V. 2004. Interactions between gender and food intake on the relationship between energy expenditure and body composition. American Journal of Clinical Nutrition. 79:385-389.

STRUCTURAL CHARACTERIZATION AND IMPROVED DETECTION OF KALE FLAVONOIDS BY ELECTROSPRAY IONIZATION MASS SPECTROMETRY. - (Peer Reviewed Journal)

Zhang, J., Satterfield, M., Brodbelt, J., Britz, S.J., Clevidence, B.A., Novotny Dura, J. 2003. Structural characterization and improved detection of kale flavonoids by electrospray ionization mass spectrometry. Analytical Chemistry. 75(23):6401-07.

ISOTOPIC LABELING AND LC-APCI-MS QUANTIFICATION FOR INVESTIGATING ABSORPTION OF CAROTENOIDS AND VITAMIN K1 FROM KALE - (Peer Reviewed Journal)

Kurilich, A.C., Britz, S.J., Clevidence, B.A., Novotny Dura, J. 2003. Isotopic labeling and lc-apci-ms quantification for investigating absorption of carotenoids and vitamin k1 from kale. Journal of Agricultural and Food Chemistry.51(7):4877-4889.

A PHYSIOLOGICAL COMPARTMENTAL MODEL DESCRIBING THE DYNAMICS OF LYCOPENE METABOLISM IN HEALTHY MEN. - (Peer Reviewed Journal)

Diwadkar-Navsariwala, V., Novotny Dura, J., Gustin, G.M., Rodvold, K.A., Sosman, J.A., Stacewicz-Sapuntzaki, J., Murray, J.L., Tiller, P.A., Bowen, P.E. 2003. A physiological compartmental model describing the dynamics of lycopene metabolism in healthy men. Journal of Lipid Research.44(10):1927-39.

THE TIME COURSE DISTRIBUTION OF A SINGLE DOSE OF 14C-LYCOPENE IN THE F344 RAT. - (Abstract Only)

Zaripheh, S., Cooke, P., Novotny Dura, J., Erdman, J.W. 2003. The time course distribution of a single dose of 14c-lycopene in the f344 rat. Meeting Abstract.

THE EFFECT OF DAILY ALCOHOL INTAKE ON BREATH ALCOHOL CONCENTRATIONS OF POST-MENOPAUSAL WOMEN AFTER A BOLUS DOSE. - (Peer Reviewed Journal)

Novotny Dura, J., Rumpler, W.V., Baer, D.J., Judd, J.T. 2003. The effect of daily alcohol intake on breath alcohol concentrations of post-menopausal women after a bolus dose. Alcohol and Alcoholism. 64:380-383.

WINSAAM: SOFTWARE FOR SIMULATION, ANALYIS, AND MODELING - (Peer Reviewed Journal)

Novotny Dura, J., Greif, P., Boston, R.C. 2003. Winsaam: Software for simulation, analyis, and modeling. Advances in Experimental Medicine and Biology. 537:343-356

PERSONALITY CHARACTERISTICS AS PREDICTORS OF UNDER-REPORTING OF ENERGY INTAKE ON 24H DIETARY RECALLS - (Peer Reviewed Journal)

Novotny Dura, J., Rumpler, W.V., Riddick, H., Judd, J.T., Baer, D.J., Mcdowell, M., Hebert, J., Briefel, R. 2003. Personality characteristics as predictors of under-reporting of energy intake on 24h dietary recalls. Journal Of The American Dietetic Association. 103:1146-1151

NUTRITIONAL ASSESSMENT OF COLORED CARROTS - (Abstract Only)

Kurilich, A.C., Novotny Dura, J., Clevidence, B.A., Britz, S.J. 2002. Nutritional assessment of colored carrots. BARC Poster Day.

INTRINSIC LABELING OF PLANTS FOR NUTRIENT BIOAVAILABILITY STUDIES - (Peer Reviewed Journal)

Novotny Dura, J., Britz, S.J., Caulfield, F.A., Beecher, G.R., Clevidence, B.A. 2003. Intrinsic labeling of plants for nutrient bioavailability studies. Advances in Experimental Medicine and Biology.537:131-140.

DETERMINATION OF 13C-LABELED AND ENDOGENOUS BETA-CAROTENE, LUTEIN, AND VITAMIN A IN HUMAN PLASMA USING QUANTITATIVE MASS SPECTROMETRY - (Peer Reviewed Journal)

Kelm, M., Flanagan, V.P., Pawlosky, R.J., Novotny Dura, J., Clevidence, B.A., Britz, S.J. 2001. Determination of 13c-labeled and endogenous beta-carotene, lutein, and vitamin a in human plasma using quantitative mass spectrometry. Lipids.36:1277-1282.

ABSORPTION OF BETA-CAROTENE FROM CARBON-13 LABELED KALE - (Abstract Only)

Novotny Dura, J., Britz, S.J., Pawlosky, R.J., Harrison, D.J., Kelm, M.A., Flanagan, V.P., Brown, E., Beecher, G.R., Clevidence, B.A. 2001. Absorption of beta-carotene from carbon-13 labeled kale. Experimental Biology.

A PHYSIOLOGIC COMPARTMENTAL ANALYSIS OF ALPHA-LINOLENIC ACID METABOLISM IN ADULT HUMANS - (Peer Reviewed Journal)

Pawlosky, R.J., Novotny Dura, J., Hibbeln, J., Salem, Jr, N. 2001. A physiologic compartmental analysis of alpha-linolenic acid metabolism in adult humans. Journal of Lipid Research. 42(8):1257-1265

METHODS FOR DETERMINING THE METABOLISM OF ALPHA-LINOLENIC ACID IN HUMANS FROM INTRINSICALLY-LABLED FOOD - (Peer Reviewed Journal)

Pawlosky, R.J., Novotny Dura, J., Britz, S.J., Clevidence, B.A. 2001. Methods for determining the metabolism of alpha-linolenic acid in humans from intrinsically-labled food. Present Knowledge in Nutrition. Book Chapter.56:75-77.

AN LC/PB METHOD FOR THE ANALYSIS OF 13 C LABELED LUTEIN AND B-CAROTENE IN KALE AND HUMAN PLASMA (BARC POSTER DAY, 2000) - (Abstract Only)

Kelm, M.A., Flanagan, V.P., Pawlosky, R.J., Novotny Dura, J., Britz, S.J. 2000. An lc/pb method for the analysis of 13 c labeled lutein and b-carotene in kale and human plasma. (BARC Poster Day, 2000). Meeting Abstract.

A SENSITIVE PROCEDURE FOR THE STUDY OF BETA-CAROTENE-D8 METABOLISM IN HUMANS USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY - (Peer Reviewed Journal)

Pawlosky, R.J., Flanagan, V.P., Novotny Dura, J. 2000. A sensitive procedure for the study of beta-carotene-d8 metabolism in humans using liquid chromatography-mass spectrometry. Journal of Lipid Research. 41:1027-1031.

A STABLE ISOTOPE LC-MS PROCEDURE TO STUDY THE METABOLISM OF 2H8-BETA- CAROTENE IN HUAMNS (EXPERIMENTAL BIOLOGY '99) - (Abstract Only)

Pawlosky, R.J., Novotny Dura, J., Flanagan, V.P. 1999. A stable isotope lc-ms procedure to study the metabolism of 2h8-beta-carotene in humans (experimental biology '99). Meeting Abstract.

COMPARTMENTAL MODELING AND BALANCE STUDIES - (Book / Chapter) - (18-Mar-99)

COMPARTMENTAL MODELING OF HUMAN LACTATION - (Peer Reviewed Journal) - (05-Dec-97)

PROTON AND HYDROXIDE DECAY KINETICS IN BUFFERED VESCILES - (Abstract Only) - (06-Mar-97)

MODELING OF ENERGY EXPENDITURE AND RESTING METABOLIC RATE DURING WEIGHT LOSS IN HUMANS - (Peer Reviewed Journal) - (14-Dec-96)