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United States Department of Agriculture

Agricultural Research Service

Theresa Pedersen
Obesity and Metabolism Research Unit
(This person is no longer with ARS)
Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Circulating levels of endocannabinoids and oxylipins altered by dietary lipids in older women are likely associated with previously identified gene targets - (Peer Reviewed Journal)
Watkins, B.A., Kim, J., Kenny, A., Pedersen, T.L., Pappan, K.L., Newman, J.W. 2016. Circulating levels of endocannabinoids and oxylipins altered by dietary lipids in older women are likely associated with previously identified gene targets . BBA Molecular and Cell Biology of Lipids. S1388-1981. doi:10.1016/j.bbalip.2016.07.007.
Intake of farmed Atlantic salmon fed soybean oil increases hepatic levels of arachidonic acid-derived oxylipins and ceramides in mice - (Peer Reviewed Journal)
Midtbø, L.K., Borkowska, A.G., Bernhard, A., Rønnevik, A.K., Lock, E., Fitzgerald, M.L., Torstensen, B.E., Liaset, B., Brattelid, T., Pedersen, T.L., Newman, J.W., Kristiansen, K., Madsen, L. 2015. Intake of farmed Atlantic salmon fed soybean oil increases hepatic levels of arachidonic acid-derived oxylipins and ceramides in mice. Journal of Nutritional Biochemistry. 26(6):585-595. doi: 10.1016/j.jnutbio.2014.12.005.
Zinc transporter 7 deficiency affects lipid synthesis in adipocytes by inhibiting insulin-dependent Akt activity and glucose uptake - (Peer Reviewed Journal)
Tepaamorndech, S., Kirschke, C.P., Pedersen, T.L., Keyes, W.R., Newman, J.W., Huang, L. 2015. Zinc transporter 7 deficiency affects lipid synthesis in adipocytes by inhibiting insulin-dependent Akt activity and glucose uptake. FEBS Journal. doi:10.1111/febs.13582.
The impact of micronutrient supplementation in alcohol-exposed pregnancies on information processing skills in Ukrainian infants - (Peer Reviewed Journal) - (13-Aug-15)
The omega-3 fatty acid DHA dose-dependently reduces atherosclerosis: a putative role for F4-neuroprostanes a specific class of peroxidized metabolites - (Peer Reviewed Journal)
Gladine, C., Newman, J.W., Durand, T., Pedersen, T.L., Galano, J., Demougeot, C., Berdeaux, O., Pujos-Guillot, E., Mazur, A., Comte, B. 2014. The omega-3 fatty acid DHA dose-dependently reduces atherosclerosis: a putative role for F4-neuroprostanes a specific class of peroxidized metabolites. PLoS One. 9(11):e111471.
Effect of omega-3 fatty acids on the oxylipin composition of lipoproteins in hypertriglyceridemic, statin-treated subjects - (Peer Reviewed Journal)
Newman, J.W., Pedersen, T.L., Brandenburg, V.R., Harris, W.S., Shearer, G.C. 2014. Effect of omega-3 fatty acids on the oxylipin composition of lipoproteins in hypertriglyceridemic, statin-treated subjects. PLoS One. 9(11):e111471. doi: 10.1371/journal.pone.0111471.
Dietary long-chain omega-3 fatty acids do not diminish eosinophilic pulmonary inflammation in mice - (Peer Reviewed Journal)
Schuster, G.U., Bratt, J., Jiang, X., Pedersen, T.L., Grapov, D., Adkins, Y.C., Kelley, D.S., Newman, J.W., Kenyon, N.J., Stephensen, C.B. 2014. Dietary long-chain omega-3 fatty acids do not diminish eosinophilic pulmonary inflammation in mice. American Journal of Respiratory Cell and Molecular Biology. doi: 10.1165/rcmb.2013-0136OC.
Direct comparison of fatty acid ratios in single cellular lipid droplets as determined by Raman spectroscopy and gas chromatography - (Peer Reviewed Journal)
Schie, I.W., Pedersen, T.L., Smith, Z., Wu, J., Newman, J.W., Huser, T., Noltel, L., Yahiatene, I. 2013. Direct comparison of fatty acid ratios in single cellular lipid droplets as determined by Raman spectroscopy and gas chromatography. Analyst. doi: 10.1039/C3AN00970J.
High dose simvastatin exhibits enhanced lipid lowering effects relative to simvastatin/ezetimibe combination therapy - (Peer Reviewed Journal)
Snowden, S.G., Grapov, D., Nygren, H., Settergren, M., D'Alexandri, F.L., Haeggstrom, J.Z., Hyotylainen, T., Oresic, M., Pedersen, T.L., Newman, J.W., Pernow, J., Wheelock, C.E. 2014. High dose simvastatin exhibits enhanced lipid lowering effects relative to simvastatin/ezetimibe combination therapy. Circulation: Cardiovascular Genetics. 7:955-964. doi: 10.1161/CIRCGENETICS.114.000606.
Oral or parenteral administration of curcumin does not prevent the growth of high-risk t(4;11) acute lymphoblastic leukemia cells engrafted into a NOD/SCID mouse model - (Peer Reviewed Journal)
Zunino, S.J., Storms, D.H., Newman, J.W., Pedersen, T.L., Keen, C.L., Ducore, J.M. 2013. Oral or parenteral administration of curcumin does not prevent the growth of high-risk t(4;11) acute lymphoblastic leukemia cells engrafted into a NOD/SCID mouse model. International Journal of Oncology. 42:741-748. DOI: 10.3892/ijo.2012.1734.
Type 2 diabetes associated changes in the plasma non-esterified fatty acids, oxylipins and endocannabinoids - (Peer Reviewed Journal)
Grapov, D., Adams, S.H., Pedersen, T.L., Garvey, W.T., Lok, K.H., Newman, J.W. 2012. Type 2 diabetes associated changes in the plasma non-esterified fatty acids, oxylipins and endocannabinoids. PLoS One. 7(11):e48852.
Dietary resveratrol does not delay engraftment, sensitize to vincristine, or inhibit growth of high-risk acute lymphoblastic leukemia cells in NOD/SCID mice - (Peer Reviewed Journal)
Zunino, S.J., Storms, D.H., Newman, J.W., Pedersen, T.L., Keen, C.L., Ducore, J.M. 2012. Dietary resveratrol does not delay engraftment, sensitize to vincristine, or inhibit growth of high-risk acute lymphoblastic leukemia cells in NOD/SCID mice. International Journal of Oncology. 41(6):2207-2212. DOI: 10.3892/ijo.2012.1650.
Quantitative profiling of oxylipins through comprehensive lc-ms/ms analysis: Application in cardiac surgery - (Peer Reviewed Journal)
Strassburg, K., Pedersen, T.L., Huijbrechts, A.M., Kortekaas, K., Lindeman, J., Dane, A., Berger, R., Brenkman, A., Hankemeier, T., Van Duynhoven, J., Kalkhoven, E., Newman, J.W., Vreeken, R. 2012. Quantitative profiling of oxylipins through comprehensive lc-ms/ms analysis: Application in cardiac surgery. Analytical and Bioanalytical Chemistry. 404(5):1413-1426.
Basal omega-3 fatty acid status affects fatty acid and oxylipin responses to high-dose n3-HUFA in healthy volunteers - (Peer Reviewed Journal)
Keenan, A.H., Pedersen, T.L., Fillaus, K., Larson, M.K., Shearer, G.C., Newman, J.W. 2012. Basal omega-3 fatty acid status affects fatty acid and oxylipin responses to high-dose n3-HUFA in healthy volunteers. Journal of Lipid Research. doi: 10.1194.
Resveratrol given intraperitoneally does not inhibit growth of high-risk t(4;11) acute lymphoblastic leukemia cells in NOD/SCID mouse model - (Peer Reviewed Journal)
Zunino, S.J., Storms, D.H., Newman, J.W., Pedersen, T.L., Keen, C.L., Ducore, J.M. 2012. Resveratrol given intraperitoneally does not inhibit growth of high-risk t(4;11) acute lymphoblastic leukemia cells in NOD/SCID mouse model. International Journal of Oncology. 40(4):1277-84. DOI:10.3892/IJO.2011.1316.
An optimized method for measuring methylmalonic acid in low volumes of serum using UPLC-MS/MS - (Peer Reviewed Journal)
Pedersen, T.L., Keyes, W.R., Shahab-Ferdows, S., Allen, L.H., Newman, J.W. 2011. An Optimized Method for Measuring Methylmalonic Acid in Low Volumes of Serum Using UPLC-MS/MS. Journal of Chromatography. B. 879, 1502-6.
ALOX5 gene variants affect eicosanoid production and response to fish oil supplementation Reprint Icon - (Peer Reviewed Journal)
Stephensen, C.B., Armstrong, P., Newman, J.W., Pedersen, T.L., Legault, J., Schuster, G., Kelley, D.S., Vikman, S., Hartiala, J., Hooman, A. 2011. ALOX5 gene variants affect eicosanoid production and response to fish oil supplementation. Journal of Lipid Research. 52(5):991-1003.
The human serum metabolome Reprint Icon - (Peer Reviewed Journal)
Psychogios, N., Hau, D.D., Peng, J., Guo, A., Mandal, R., Bouatra, S., Sinelnikov, I., Krishnamurthy, R., Eisner, R., Gautam, B., Young, N., Xia, J., Knox, C., Dong, E., Huang, P., Hollander, Z., Pedersen, T.L., Smith, S.R., Bamforth, F., Greiner, R., Mcmanus, B., Newman, J.W., Goodfriend, T., Wishart, D.S. 2011. THE HUMAN SERUM METABOLOME. PLoS One. 6(2): e16957.
12- and 15-lipoxygenases in human carotid atherosclerotic lesions: Associations with cerebrovascular symptoms Reprint Icon - (Peer Reviewed Journal)
Gertow, K., Nobili, E., Folkersen, L., Newman, J.W., Pedersen, T.L., Swedenborg, J., Paulsson-Berne, G., Kuhn, H., Hedin, U., Wheelock, C.E., Hansson, G.K., Haeggstrom, J.Z., Gabrielsen, A. 2011. 12- and 15-lipoxygenases in human carotid atherosclerotic lesions: Associations with cerebrovascular symptoms. Atherosclerosis. 215:411-416.
Effects of dynamic exercise on plasma arachidonic acid epoxides and diols in human volunteers - (Peer Reviewed Journal)
Giordano, R.M., Newman, J.W., Pedersen, T.L., Ramos, M.I., Stebbins, C. 2011. Effects of dynamic exercise on plasma arachidonic acid epoxides and diols in human volunteers. American Journal of Clinical Nutrition. doi: 21, 471-479.
Insight in modulation of inflammation in response to diclofenac intervention: a human intervention study - (Peer Reviewed Journal)
Van Erk, M.J., Wopereis, S., Rubingh, C., Van Vliet, T., Verheij, E., Cnubben, N., Pedersen, T.L., Newman, J.W., Age, S., Van Der Greef, J., Hendriks, H., Van Ommen, B. 2010. Insight in modulation of inflammation in response to diclofenac intervention: a human intervention study. Biomed Central (BMC) Genomics. 3:5.
Detection of omega-3 oxylipins in human plasma and response to treatment with omega-3 acid ethyl esters Reprint Icon - (Peer Reviewed Journal)
Shearer, G.C., Harris, W.S., Pedersen, T.L., Newman, J.W. 2010. DETECTION OF OMEGA-3 OXYLIPINS IN HUMAN PLASMA AND RESPONSE TO TREATMENT WITH OMEGA-3 ACID ETHYL ESTERS. Journal of Lipid Research. 51(8):2074-81.
TRIGLYCERIDE-RICH LIPOPROTEIN LIPOLYSIS RELEASES NEUTRAL AND OXIDIZED FREE FATTY ACIDS THAT INDUCE ENDOTHELIAL CELL INFLAMMATION Reprint Icon - (Peer Reviewed Journal)
Wang, L., Gill, R., Pedersen, T.L., Higgins, L.J., Newman, J.W., Rutledge, J.C. 2008. Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized free fatty acids that induce endothelial cell inflammation. Journal of Lipid Research. Papers in press published ahead of print, doi:10.1194/jlr.M700505-JLR200
INCREASED BLOOD PRESSURE IN MICE LACKING CYTOCHROME P450 2J5 Reprint Icon - (Peer Reviewed Journal)
Athirakul, K., Bradbury, A.J., Graves, J.P., Degraff, L.M., Ma, J., Zhao, Y., Couse, J.F., Quigley, R., Harder, D.R., Zhao, X., Imig, J.D., Pedersen, T.L., Newman, J.W., Hammock, B.D., Conley, A.J., Korach, K.S., Coffman, T.M., Zeldin, D.C. 2008. INCREASED BLOOD PRESSURE IN MICE LACKING CYTOCHROME P450 2J5. Federation of American Societies for Experimental Biology Conference. 12):4096-108.
ARS News Articles
Last Modified: 8/24/2016
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