Projects

Technologies for Detecting and Determining the Bioavailability of Bacterial Toxins Appropriated (D)   Accession Number: 421099

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Review of the inhibition of biological activities of selected food-related toxins by natural compounds - (Peer Reviewed Journal)

Friedman, M., Rasooly, R. 2013. Review of the inhibition of biological activities of selected food-related toxins by natural compounds. Toxins. 5:743-775. doi: 10.3390/toxins50x100x..

Purification and characterization of Shiga toxin 2f, an immunologically unrelated subtype of Shiga toxin 2 - (Peer Reviewed Journal)

Skinner, C.B., Mcmahon, S.A., Rasooly, R., Carter, J.M., He, X. 2013. Purification and characterization of Shiga toxin 2f, an immunologically unrelated subtype of Shiga toxin 2. PLoS One. 8(3):e59760. doi:10.1371/journal.pone.0059760.

Milk inhibits the biological activity of ricin - (Peer Reviewed Journal)

Rasooly, R., He, X., Friedman, M. 2012. Milk inhibits the biological activity of ricin. Journal of Biological Chemistry. 287(33):27924-27929. doi:10.1074/jbc.M112.362988.

TNF as biomarker for rapid quantification of active Staphylococcus enterotoxin A in food - (Peer Reviewed Journal)

Rasooly, R., Hernlem, B.J. 2012. TNF as biomarker for rapid quantification of active Staphylococcus enterotoxin A in food. Sensors. 12:5978-5985. doi:10.3390/s120505978.

Techniques for rapid detection and quantification of active foodborne Staphylococcus Enterotoxin(Abstract) - (Abstract Only)

Hernlem, B.J., Rasooly, R. 2012. Techniques for rapid detection and quantification of active foodborne Staphylococcus Enterotoxin(Abstract). Meeting Abstract. Poster no. B266.

Sensitive bioassay for detection of biologically active ricin in food - (Peer Reviewed Journal)

Rasooly, R., He, X. 2012. Sensitive bioassay for detection of biologically active ricin in food. Journal of Food Protection. 75(5):951-954.

CD154 as a potential early molecular biomarker for rapid quantification analysis of active Staphylococcus enterotoxin A - (Peer Reviewed Journal)

Rasooly, R., Hernlem, B.J. 2011. CD154 as a potential early molecular biomarker for rapid quantification analysis of active Staphylococcus enterotoxin A. FEMS Immunology and Medical Microbiology. 64(2):169-174.

Evaluation and comparison of three enzyme-linked immunosorbent assay formats for the detection of ricin in milk and serum - (Peer Reviewed Journal)

He, X., Mcmahon, S.A., Rasooly, R. 2012. Evaluation and comparison of three enzyme-linked immunosorbent assay formats for the detection of ricin in milk and serum. Biocatalysis and Agricultural Biotechnology. 1(2):105-109. doi:10.1016/j.bcab.2011.08.016.

Food compounds inhibit Staphylococcus aureus bacteria and the toxicity of Staphylococcus Enterotoxin A (SEA) associated with atopic dermatitis - (Book / Chapter)

Rasooly, R., Friedman, M. 2012. Food compounds inhibit Staphylococcus aureus bacteria and the toxicity of Staphylococcus Enterotoxin A (SEA) associated with atopic dermatitis. In: Esparza-Gordillo, J., editor. Atopic Dermatitis-Disease Etiology and Clinical Management. Croatia: Intech Europe. p. 387-404

The olive compound 4-hydroxytyrosol inactivates Staphyloccoccus aureus bacteria and Staphylococcal enterotoxin A (SEA) - (Peer Reviewed Journal)

Friedman, M., Rasooly, R., Do, P.M., Henika, P.R. 2011. The olive compound 4-hydroxytyrosol inactivates Staphyloccoccus aureus bacteria and Staphylococcal enterotoxin A (SEA). Journal of Food Science. 76:M558-M558. doi:10.1111/j.1750-3841.2001.02365.x.

Auto-presentation of Staphylococcal enterotoxin A by mouse CD4+ T cells - (Peer Reviewed Journal)

Rasooly, R., Do, P.M., Hernlem, B.J. 2011. Auto-presentation of Staphylococcal enterotoxin A by mouse CD4+ T cells. Open Journal of Immunology. 1(1):8-14. doi:10.4236/oji.2011.11002.

Clostridium botulinum neurotoxin type B is heat-stable in milk and not inactivated by pasteurization - (Peer Reviewed Journal)

Rasooly, R., Do, P.M. 2010. Clostridium botulinum neurotoxin type B is heat-stable in milk and not inactivated by pasteurization. Journal of Agricultural and Food Chemistry. 58:12557-12561.

Ingested Shiga Toxin 2 (Stx2) Causes Histopathological Changes in Kidney, Spleen and Thymus Tissues and Mortality in Mice - (Peer Reviewed Journal)

Rasooly, R., Do, P.M., Griffey, S.M., Vilches-Moure, J.G., Friedman, M. 2010. Ingested Shiga Toxin 2 (Stx2) Causes Histopathological Changes in Kidney, Spleen and Thymus Tissues and Mortality in Mice. Journal of Agricultural and Food Chemistry. (58):9821-9286

Inhibition of Biological Activity of Staphylococcal Enterotoxin A (SEA) by Apple Juice and Apple Polyphenols - (Peer Reviewed Journal)

Rasooly, R., Do, P.M., Friedman, M. 2010. Inhibition of Biological Activity of Staphylococcal Enterotoxin A (SEA) by Apple Juice and Apple Polyphenols. Journal of Agricultural and Food Chemistry. 58:5421-5426.

Inhibition of Shiga Toxin 2 (Stx2) in Apple Juices and its Resistance to Pasteurization - (Peer Reviewed Journal)

Rasooly, R., Do, P.M., Levin, C.E., Friedman, M. 2010. Inhibition of Shiga Toxin 2 (Stx2) in Apple Juices and its Resistance to Pasteurization. Applied and Environmental Microbiology. Vol. 75(5):M296-M301.

Shiga toxin Stx2 is heat-stable and not inactivated by pasteurization - (Peer Reviewed Journal)

Rasooly, R., Do, P.M. 2009. Shiga toxin Stx2 is heat-stable and not inactivated by pasteurization. International Journal of Food Microbiology. 136(2010):290-294

Detection of Protein Toxins - (Abstract Only)

Brandon, D.L., Cheng, L.W., He, X., Rasooly, R., Scotcher, M.C., Stanker, L.H., Carter, J.M. 2009. Detection of Protein Toxins. Meeting Abstract. Poster No. 8.

In vitro cell based assay for activity analysis of staphylococcal enterotoxin A in food - (Peer Reviewed Journal)

Rasooly, R., Do, P.M. 2009. In vitro cell based assay for activity analysis of staphylococcal enterotoxin A in food. FEMS Immunology and Medical Microbiology 56(2009): 172-178.

Immunochemical technologies for replacement of rodent bioassays in sensitive detection of toxins in foods - (Proceedings)

Carter, J.M., Cheng, L.W., He, X., Rasooly, R., Brandon, D.L., Stanker, L.H. 2010. Immunochemical technologies for replacement of rodent bioassays in sensitive detection of toxins in foods. Proceedings from Biodetection Technologies 6th Edition. 5:75-95.

Effect of food matrices on the biological activity of ricin - (Peer Reviewed Journal)

He, X., Lu, S.S., Cheng, L.W., Rasooly, R., Carter, J.M. 2008. Effect of food matrices on the biological activity of ricin. Journal of Food Protection 71(10):2053-2058.

Bactericidal activity of the food color additive Phloxine B against Staphylococcus aureus and other food borne microbial pathogens - (Abstract Only) - (20-May-08)

In vitro peptide cleavage assay for detection of Botulinum Neurotoxin-A activity in food - (Peer Reviewed Journal)

Rasooly, R., Do, P.M. 2008. In vitro peptide cleavage assay for detection of Botulinum Neurotoxin-A activity in food. Applied and Environmental Microbiology. 74(14):4309-4313

Detection of botulinum neurotoxin-A activity in food by peptide cleavage assay - (Peer Reviewed Journal)

Rasooly, R., Stanker, L.H., Carter, J.M., Do, P.M., Cheng, L.W., He, X., Brandon, D.L. 2008. In vitro peptide cleavage assay for detection of Botulinum Neurotoxin-A activity in food. International Journal of Food Microbiiology. 126 (2008):135-139

Docosahexaenoic Acid (DHA) But Not Eicosapentaenoic Acid (EPA) Reverses Trans-10, Cis-12 Conjugated Linoleic Acid Induced Insulin Resistance in Mice1 - (Peer Reviewed Journal)

Vemuri, M., Kelley, D.S., Mackey, B.E., Rasooly, R., Bartolini, G.L. Docosahexaenoic Acid (DHA) But Not Eicosapentaenoic Acid (EPA) Reverses Trans-10, Cis-12 Conjugated Linoleic Acid Induced Insulin Resistance in Mice. Metabolic Syndrome and Related Disorders, 2007 Vol.5, No.4:315-322.

Phloxine B, aversatile bacterial stain - (Peer Reviewed Journal)

Rasooly, R. 2007. Phloxine B, aversatile bacterial stain. International Journal of Food Microbiology.157: 29-34.

DIETARY T10, C-12-CONJUGATED LINOLEIC ACID REDUCES THE EXPRESSION OF FATTY ACID OXIDATION AND DRUG DETOXIFICATION ENZYMES IN MOUSE LIVER - (Peer Reviewed Journal)

Rasooly, R., Kelley, D.S., Greg, J., Mackey, B.E. Dietary t10, c-12-conjugated linoleic acid reduces the expression of fatty acid oxidation and drug detoxification enzymes in mouse liver. Journal of Nutrition. 97:58-66, 2007.

CONSUMPTION OF BING SWEET CHERRIES LOWERS CIRCULATING CONCENTRATIONS OF INFLAMMATION MARKERS IN HEALTHY MEN AND WOMEN - (Peer Reviewed Journal)

Kelley, D.S., Rasooly, R., Jacob, R.A., Kader, A.A., Mackey, B.E. 2006. CONSUMPTION OF BING SWEET CHERRIES LOWERS CIRCULATING CONCENTRATIONS OF INFLAMMATION MARKERS IN HEALTHY MEN AND WOMEN. Journal of Nutrition. 136:981-986, 2006.

RETINOID X RECEPTOR AGONISTS INCREASE BCL2A1 EXPRESSION AND DECREASE APOPTOSIS OF NAÏVE T LYMPHOCYTES - (Peer Reviewed Journal)

Rasooly, R., Schuster, G.U., Gregg, J.P., Xiao, J.H., Chandraratna, R., Stephensen, C.B. 2005. RETINOID X RECEPTOR AGONISTS INCREASE BCL2A1 EXPRESSION AND DECREASE APOPTOSIS OF NAÏVE T LYMPHOCYTES. Journal of Immunology. 175:7916-7929.