Projects

Mitigating the Risk of Transmission and Environmental Contamination of Transmissible Spongiform Encephalopathies Appropriated (D)   Accession Number: 422167

DISSEMINATION OF ABNORMAL PRION PROTEIN IN THE NEURAL AND EXTRANEURAL TISSUES OF WILD ROCKY MOUNTAIN ELK Specific Cooperative Agreement (S)   Accession Number: 413374

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Accumulation of PrP-Sc in hemal nodes of naturally and experimentally scrapie-infected sheep - (Peer Reviewed Journal)

Dassanayake, R.P., Truscott, T.C., Özyigit, Ö.M., Zhuang, D., Schneider, D.A., O'Rourke, K.I. 2013. Accumulation of PrP-Sc in hemal nodes of naturally and experimentally scrapie-infected sheep. BioMed Central (BMC) Veterinary Research. doi:10.1186/1746-6148-9-82.

Ovine progressive pneumonia virus is transmitted more effectively via aerosol nebulization than oral administration - (Peer Reviewed Journal)

Herrmann-Hoesing, L.M., White, S.N., Neiswanger-Broughton, L.E., Johnson, W.C., Noh, S.M., Schneider, D.A., Li, H., Taus, N.S., Reynolds, J.O., Truscott, T.C., Dassanayake, R.P., Knowles Jr, D.P. 2012. Ovine progressive pneumonia virus is transmitted more effectively via aerosol nebulization than oral administration. Open Journal of Veterinary Medicine . 2(3):113-119.

Differential immunoreactivity of goat derived scrapie following in vitro misfolding versus mouse bioassay - (Peer Reviewed Journal)

Madsen-Bouterse, S.A., Zhuang, D., Orourke, K.I., Schneider, D.A. 2012. Differential immunoreactivity of goat derived scrapie following in vitro misfolding versus mouse bioassay. Biochemical and Biophysical Research Communications. 423(4):770-774.

Diagnostic accuracy of rectal mucosa biopsy testing for chronic wasting disease within white-tailed deer (Odocoileus virginianus) herds in North America:Effects of age,sex,polymorphism at PRNP codon 96,and disease progression - (Peer Reviewed Journal)

Thomsen, B.V., Schneider, D.A., O'Rourke, K., Gidlewski, T., Mclane, J., Allen, R.W., Mcisaac, A.A., Mitchell, G.B., Keane, D.P., Spraker, T., Balachandran, A. 2012. Diagnostic accuracy of rectal mucosa biopsy testing for chronic wasting disease within white-tailed deer (Odocoileus virginianus) herds in North America:Effects of age,sex,polymorphism at PRNP codon 96,and disease progression. J Vet Diagn Invest. 24(5):878-87.

Acute and persistent infection by a transfected Mo7 strain of Babesia bovis - (Peer Reviewed Journal)

Suarez, C.E., Laughery, J., Schneider, D.A., Sondgeroth, K.S., Mcelwain, T.F. 2012. Acute and persistent infection by a transfected Mo7 strain of Babesia bovis. Molecular and Biochemical Parasitology. 185(1):52-7.

Ovine herpesvirus 2 infection in american bison: virus and host dynamics in the development of sheep-associated malignant catarrhal fever - (Peer Reviewed Journal)

Cunha, C.W., Gailbreath, K.L., O'Toole, D., Knowles Jr, D.P., Schneider, D.A., White, S.N., Taus, N.S., Davis, C.J., Davis, W.C., Li, H. 2012. Ovine herpesvirus 2 infection in american bison: virus and host dynamics in the development of sheep-associated malignant catarrhal fever. Veterinary Microbiology. 159:307-319.

Transmissibility of caprine scrapie in ovine transgenic mice - (Peer Reviewed Journal)

Orourke, K.I., Schneider, D.A., Spraker, T.R., Dassayanake, R., Highland, M., Zhuang, D., Truscott, T.C. 2012. Transmissibility of caprine scrapie in ovine transgenic mice. BioMed Central (BMC) Veterinary Research. 8:42.

Disease-associated prion protein in neural and lymphoid tissues of mink (Mustela vison) inoculated with transmissible mink encephalopathy - (Peer Reviewed Journal)

Schneider, D.A., Harrington, R., Zhuang, D., Yan, H., Truscott, T.C., Dassanayake, R., Orourke, K.I. 2012. Disease-associated prion protein in neural and lymphoid tissues of mink (Mustela vison) inoculated with transmissible mink encephalopathy. Journal of Comparative Pathology. 147:508-521.

Extended scrapie incubation time in goats singly heterozygous for PRNP S146 or K222 - (Peer Reviewed Journal)

White, S.N., Reynolds, J.O., Waldron, D.F., Schneider, D.A., Orourke, K.I. 2012. Extended scrapie incubation time in goats singly heterozygous for PRNP S146 or K222. Gene. 501(1):49-51.

Cell surface expression of PrP-c and the presence of scrapie prions in the blood of goats - (Peer Reviewed Journal)

Dassanayake, R.P., Schneider, D.A., Hoesing, L.M., Truscott, T.C., Davis, W.C., Orourke, K.I. 2012. Cell surface expression of PrP-c and the presence of scrapie prions in the blood of goats. Journal of General Virology. 1127-1131.

Classical scrapie prions in ovine blood are associated with B lymphocytes and platelets-rich plasma - (Peer Reviewed Journal)

Dassanayake, R.P., Schneider, D.A., Truscott, T.C., Young, A.J., Zhuang, D., Orourke, K.I. 2011. Classical scrapie prions in ovine blood are associated with B lymphocytes and platelets-rich plasma. BioMed Central (BMC) Veterinary Research. 7:75.

Cytokine antibody array analysis in brain and periphery of scrapie-infected Tg338 mice - (Peer Reviewed Journal)

Newsom, D.M., Liggitt, H.D., Orourke, K.I., Zhuang, D., Schneider, D.A., Harrington, R.D. 2011. Cytokine antibody array analysis in brain and periphery of scrapie-infected Tg338 mice. Comparative Immunology Microbiology and Infectious Diseases. 34(5):387-97.

Expression of Anaplasma marginale ankyrin repeat-containing proteins during infection of the mammalian host and tick vector - (Peer Reviewed Journal)

Solomon, R.S., Schneider, D.A., Brayton, K.A., Ueti, M.W., Graca, T., Futse, J.E., Noh, S.M., Baszler, T.V., Palmer, G.H. 2011. Expression of Anaplasma marginale ankyrin repeat-containing proteins during infection of the mammalian host and tick vector. Infection and Immunity. 79(7):2847-2855.

Scant PrP-Sc accumulation in the placentas of goats with naturally acquired scrapie - (Peer Reviewed Journal)

Orourke, K.I., Zhuang, D., Truscott, T.C., Yan, H., Schneider, D.A. 2011. Scant PrP-Sc accumulation in the placentas of goats with naturally acquired scrapie. BioMed Central (BMC) Veterinary Research. 7(1):7.

Dynamics of bovine spleen cell populations during the response to acute Babesia bovis infection: an immunohistological study - (Peer Reviewed Journal)

Schneider, D.A., Yan, H., Bastos, R.G., Johnson, W.C., Gavin, P.R., Allen, A.J., Barrington, G.M., Hoesing, L.M., Knowles Jr, D.P., Goff, W.L. 2010. Dynamics of bovine spleen cell populations during the response to acute Babesia bovis infection: an immunohistological study. Parasite Immunology. Available: onlinelibrary.wiley.com/doi/10.1111/j.1365-3024.2010.01249.x/pdf.

The bovine spleen: Interactions among splenic cell populations in the innate immunologic control of hemoparasitic infections - (Review Article)

Goff, W.L., Bastos, R.G., Brown, W.C., Johnson, W.C., Schneider, D.A. 2010. The bovine spleen: interactions among splenic cell populations in the innate immunologic control of hemoparasitic infections. Veterinary Immunology and Immunopathology. 138:1-14.

Sheep (Ovis aries) airway epithelial cells support ovine herpesvirus 2 lytic replication in vivo - (Peer Reviewed Journal)

Taus, N.S., Schneider, D.A., Oaks, J.L., Yan, H., Gailbreath, K.L., Knowles Jr, D.P., Li, H. 2010. Sheep (Ovis aries) airway epithelial cells support ovine herpesvirus 2 lytic replication in vivo. Veterinary Microbiology. 145(1-2):47-53.

Ovine Progressive Pneumonia Virus Capsid Antigen as Found in CD163- and CD172a-Positive Alveolar Macrophages of Persistently Infected Sheep - (Peer Reviewed Journal)

Hoesing, L.M., Noh, S.M., Snekvik, K.R., White, S.N., Schneider, D.A., Truscott, T.C., Knowles Jr, D.P. 2010. Ovine Progressive Pneumonia Virus Capsid Antigen as Found in CD163- and CD172a-Positive Alveolar Macrophages of Persistently Infected Sheep. Veterinary Pathology. 47(3):518-528.

Sensitive detection of PrPCWD in rectoanal mucosa-associated lymphoid tissue from preclinical white-tailed deer - (Abstract Only)

Schneider, D.A., Orourke, K.I., Balachandran, A., Keane, D. 2009. Sensitive Detection of PrPCWD in Rectoanal Mucosa-Associated Lymphoid Tissue from Preclinical White-Tailed Deer. United States Animal Health Association Proceedings. pg.224-225.

Diagnosis of preclinical CWD in farmed white-tailed deer in Canada by the immunohistochemical examination of recto-anal mucosa- associated lymphoid tissue (RAMALT) - (Abstract Only)

Balachandran, A., Thomsen, B.V., Gidlewski, T., Spraker, T.R., Mitchell, G., Soutyrine, A., Harrington, N.P., Munger, R., Schneider, D.A., Orourke, K.I. 2009. Diagnosis of preclinical CWD in farmed white-tailed deer in Canada by the immunohistochemical examination of recto-anal mucosa- associated lymphoid tissue (RAMALT). NeuroPrion Workshop: New developments in TSEs of domestic and wild animals. pg.9

Validation of Use of Rectoanal Mucosa-Associated Lymphoid Tissue for Immunohistochemical Diagnosis of Chronic Wasting Disease in White-Tailed Deer (Odocoileus virginianus) - (Peer Reviewed Journal)

Keane, D., Barr, D., Osborn, R., Langenberg, J., Orourke, K.I., Schneider, D.A., Bochsler, P. 2009. Validation of Use of Rectoanal Mucosa-Associated Lymphoid Tissue for Immunohistochemical Diagnosis of Chronic Wasting Disease in White-Tailed Deer (Odocoileus virginianus). Journal of Veterinary Diagnostic Investigation. 47(5):1412-1417.

Blood chimerism confounds genetic relative susceptibility testing for classical scrapie in sheep - (Peer Reviewed Journal)

Schneider, D.A., Tibary, A., Raudsepp, T., Das, P.J., Orourke, K.I. 2009. Blood chimerism confounds genetic relative susceptibility testing for classical scrapie in sheep. Journal of Veterinary Diagnostic Investigation. 21(3):295-305.

Antemortem detection of PrP-CWD in preclinical, ranch-raised Rocky Mountain elk (Cervus elaphus nelsoni) by biopsy of the rectal mucosa - (Peer Reviewed Journal)

Spraker, T.R., Vercauteren, K.C., Gidlewski, T., Schneider, D.A., Munger, R., Balanchandran, A., Orourke, K.I. 2009. Antemortem detection of PrP-CWD in preclinical, ranch-raised Rocky Mountain elk (Cervus elaphus nelsoni) by biopsy of the rectal mucosa. Journal of Veterinary Diagnostic Investigation. 21(1):15-24.

Myenteric neurons of the ileum that express somatostatin are a target of prion neuroinvasion in an alimentary model of sheep scrapie - (Peer Reviewed Journal)

Schneider, D.A., Yan, H., Fry, L.M., Alverson, J., White, S.N., Orourke, K.I. 2008. Myenteric neurons of the ileum that express somatostatin are a target of prion neuroinvasion in an alimentary model of sheep scrapie. Acta Neuropathologica. 115(6):651-661.

A species barrier limits transmission of chronic wasting disease to mink (Mustela vison) - (Peer Reviewed Journal)

Harrington, R.D., Baszler, T.V., Orourke, K.I., Schneider, D.A., Spraker, T.R., Liggitt, H.D., Knowles Jr, D.P. 2008. A species barrier limits transmission of chronic wasting disease to mink (Mustela vison). Journal of General Virology. 89(4):1086-1096.