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United States Department of Agriculture

Agricultural Research Service

Related Topics

James Zhu
Foreign Animal Disease Research
Computational Biologist

Phone: (631) 323-3186
Fax: (631) 323-3006
40550 ROUTE 25
ORIENT POINT, NY, 11957

Projects
COUNTERMEASURES TO CONTROL FOREIGN ANIMAL DISEASES OF SWINE
Appropriated (D)
  Accession Number: 422018
INTERVENTION STRATEGIES TO SUPPORT THE GLOBAL CONTROL AND ERADICATION OF FOOT-AND-MOUTH DISEASE VIRUS (FMDV)
Appropriated (D)
  Accession Number: 422203
ECOLOGY AND PATHOGENESIS OF RE-EMERGING VESICULAR STOMATITIS VIRUS (VSV) IN NORTH AMERICA
Appropriated (D)
  Accession Number: 422286
COUNTERMEASURES FOR FOOT-AND-MOUTH DISEASE UTILIZING DIAGNOSTICS, BIOTHERAPEUTICS, A NOVEL VACCINE PLATFORM AND IMPROVED CHALLENGE SYSTEMS
Reimbursable (R)
  Accession Number: 421628
Evaluation of Recombinant Replication-Defective Adenoviruses Which Induce Anti-Viral Activity in Cattle
Specific Cooperative Agreement (S)
  Accession Number: 424153

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Fusion protein IRF7/3(5D) efficiently controls Foot-and-Mouth Disease Virus particles - (Peer Reviewed Journal)
Ramirez-Carvajal, L., Long, C.R., Zhu, J.J., Diaz San Segundo, F.C., Rodriguez, L.L., De Los Santos, T.B. 2014. Fusion protein IRF7/3(5D) efficiently controls Foot-and-Mouth Disease Virus particles. Journal of Virology. DOI:10.1128/JVI.00372-14.
Mechanisms of foot-and-mouth disease virus tropism inferred from differential tissue gene expression Reprint Icon - (Peer Reviewed Journal)
Zhu, J.J., Arzt, J., Puckette, M.C., Smoliga, G.R., Pacheco Tobin, J., Rodriguez, L.L. 2013. Mechanisms of foot-and-mouth disease virus tropism inferred from differential tissue gene expression. PLoS One. 8(5):e64119. DOI:10.1371/journal.pone.0064119.
Antiviral activity of bovine type III interferon against foot-and-mouth disease virus - (Peer Reviewed Journal)
Diaz-San Segundo, F., Weiss, M., Perez-Martin, E., Koster, M.J., Zhu, J.J., Grubman, M.J., De Los Santos, T.B. 2011. Antiviral activity of bovine type III interferon against foot-and-mouth disease virus. Virology. 413(2):283-292.
Differential gene expression in bovine cells infected with wild type and leaderless foot-and-mouth disease virus - (Peer Reviewed Journal)
Zhu, J.J., Weiss, M., Grubman, M.J., De Los Santos, T.B. 2010. Differential gene expression in bovine cells infected with wild type and leaderless foot-and-mouth disease virus. Virology. 404(1):32-40.
IgA antibody response of swine to foot-and-mouth disease virus infection and vaccination Reprint Icon - (Review Article)
Pacheco Tobin, J., Butler, J.E., Jew, J., Ferman, G., Zhu, J.J., Golde, W.T. 2010. IgA antibody response of swine to foot-and-mouth disease virus infection and vaccination. Clinical and Vaccine Immunology. p. 550-558.
IgA antibody response of swine to foot-and-mouth disease virus (FMDV) infection and vaccination - (Peer Reviewed Journal)
Pacheco Tobin, J., Butler, J.E., Jew, J., Ferman, G.S., Zhu, J.J., Golde, W.T. 2010. IgA antibody response of swine to foot-and-mouth disease virus (FMDV) infection and vaccination. Clinical and Vaccine Immunology. 17(4):550-558.
Mutations in the classical swine fever virus NS4B protein affects virulence in swine - (Abstract Only)
Fernandez Sainz, I., Gladue, D.P., Holinka-Patterson, L.G., O'Donnell, V.K., Gudmundsdottir, I., Prarat, M.V., Patch, J.R., Golde, W.T., Zhiqiang, L., Risatti, G.R., Zhu, J.J., Borca, M.V. 2009. Mutations in the classical swine fever virus NS4B protein affects virulence in swine. Proceedings. P. 143.
Mutations in classical swine fever virus NS4B affect virulence in swine - (Peer Reviewed Journal)
Fernandez-Sainz, I., Gladue, D.P., Holinka-Patterson, L.G., O'Donnell, V.K., Gudmundsdottir, I., Prarat, M.V., Patch, J.R., Golde, W.T., Lu, Z., Risatti, G.R., Zhu, J.J., Borca, M.V. 2010. Mutations in classical swine fever virus NS4B affect virulence in swine. Journal of Virology. 84(3):1536-1549.
The region between the two polyprotein initiation codons of foot-and-mouth disease virus is critical for virulence in cattle - (Peer Reviewed Journal)
Piccone, M.E., Pacheco Tobin, J., Pauszek, S.J., Borca, M.V., Rieder, A.E., Kramer Jr, E.V., Zhu, J.J., Rodriguez, L.L. 2010. The region between the two polyprotein initiation codons of foot-and-mouth disease virus is critical for virulence in cattle. Virology. 396:152-159.
Functional genomics approach to understand the role of Lpro in FMDV virulence - (Abstract Only)
De Los Santos, T.B., Grubman, M.J., Zhu, J.J. 2009. Functional genomics approach to understand the role of Lpro in FMDV virulence. American Society for Virology Meeting. Paper No. 9-21: P.262.
A Conserved Domain in the Leader Proteinase of Foot-and-Mouth Disease Virus is Required for Proper Sub-Cellular Localization and Function - (Peer Reviewed Journal)
De Los Santos, T.B., Diaz-San Segundo, F., Zhu, J.J., Koster, M.J., Dias, C., Grubman, M.J. 2008. A Conserved Domain in the Leader Proteinase of Foot-and-Mouth Disease Virus is Required for Proper Sub-Cellular Localization and Function. Journal of Virology. 83(4):1800-1810.
Patterns of gene expression in swine macrophages infected with classical swine fever virus detected by microarray - (Peer Reviewed Journal)
Gladue, D.P., Zhu, J.J., Holinka-Patterson, L.G., Fernandez-Sainz, I., Prarat, M.V., O'Donnell, V.K., Borca, M.V. 2010. Patterns of gene expression in swine macrophages infected with classical swine fever virus detected by microarray. Virology. 138(1-2):89-96.
Cellular Changes Induced by Adenovirus Vaccine Vectors Expressing Foot-and-Mouth Disease Virus Structural and Nonstructural Proteins - (Abstract Only)
Moraes, M., O'Donnell, V.K., Burrage, T.G., Pena, L., Diaz-San Segundo, F., Koster, M.J., Zhu, J., Grubman, M.J. 2008. Cellular Changes Induced by Adenovirus Vaccine Vectors Expressing Foot-and-Mouth Disease Virus Structural and Nonstructural Proteins. European Study Group on the Molecular Biology of Picornaviruses. P 203
A Conserved Domain in the Leader Proteinase of Foot-and-Mouth Disease Virus is Required for Proper Subcellular Localization and Function - (Abstract Only)
De Los Santos, T., San Segundo-Diaz, F., Zhu, J., Koster, M.J., Grubman, M.J. 2008. A conserved domain in the leader proteinase of foot-and-mouth disease virus is required for proper subcellular localization and function. European Study Group on the Molecular Biology of Picornaviruses. P 86
DNA microarray analysis reveals crosstalk of Salmonella enterica serovar Typhimurium with AI-2 of Escherichia coli - (Abstract Only)
Jesudhasan, P.R., Cepeda, M.L., Widmer, K., Dowd, S.E., Soni, K.A., Hume, M.E., Zhu, J., Pillai, S.D. 2007. DNA microarray analysis reveals crosstalk of Salmonella enterica serovar Typhimurium with AI-2 of Escherichia coli [abstract]. In: American Society for Microbiology Cell to Cell Communication in Bacteria Abstracts, October 7-10, 2007, Austin, Texas. No. 110A.
Gene regulation of Salmonella enterica serovar Typhimurium as influenced by LuxS/AI-2 - (Abstract Only)
Jesudhasan, P.R., Cepeda, M.L., Widmer, K., Dowd, S.E., Soni, K.A., Hume, M.E., Zhu, J., Pillai, S.D. 2007. Gene regulation of Salmonella enterica serovar Typhimurium as influenced by LuxS/AI-2 [abstract]. American Society for Microbiology Cell to Cell Communication in Bacteria Abstracts, October 7-10, 2007, Austin, Texas. No. 111B.
Autoinducer-2 controls virulence of Salmonella enterica serovar Typhimurium - (Abstract Only)
Jesudhasan, P.R., Cepeda, M.L., Widmer, K., Dowd, S.E., Soni, K.A., Hume, M.E., Zhu, J., Pillai, S.D. 2007. Autoinducer-2 controls virulence of Salmonella enterica serovar Typhimurium [abstract]. American Society for Microbiology Cell to Cell Communication in Bacteria Abstracts, October 7-10, 2007, Austin, Texas. No. 108A.
Mutations in the Carboxyl Terminal Region of E2 Glycoprotein of Classical Swine Fever Virus are Responsible for Viral Attenuation in Swine - (Abstract Only)
Risatti, G.R., Holinka, L.G., Fernanez-Sainz, I., Carrillo, C., Kutish, G., Lu, Z., Zhu, J., Rock, D.L., Borca, M.V., 2007, Mutations in the Carboxyl Terminal Region of E2 Glycoprotein of Classical Swine Fever Virus are Responsible for Viral Attenuation in Swine. Positive Strand RNA Virus International Conference Proceedings. P2-K27, p.116
Mutations in the Carboxyl Terminal Region of E2 Glycoprotein of Classical Swine Fever Virus is Responsible for Viral Attenuation in Swine - (Peer Reviewed Journal)
Risatti, G., Holinka, L.G., Fernandez-Sainz, I., Carrillo, C., Kutish, G.F., Lu, Z., Zhu, J., Rock, D.L., Borca, M.V. 2007. Mutations in the Carboxyl Terminal Region of E2 Glycoprotein of Classical Swine Fever Virus is Responsible for Viral Attenuation in Swine. Virology. 364 (2): 371-82.
Genomics and vaccine development - (Peer Reviewed Journal)
Gay, C.G., Zuerner, R., Bannantine, J.P., Lillehoj, H.S., Zhu, J., Green, R.D., Pastoret, P.P. 2007. Genomics and vaccine development. OIE Rev. Sci Tech. 26:49-67.
Gene Expression Profiling to Study 12 Cytokine Production after Eimeria Infection - (Abstract Only) - (01-Jun-03)
Mapping Quantitative Trait Loci Affecting Disease Resistance to Avian Coccidiosis (73rd Necab Mtg, College Park, Md) - (Abstract Only) - (20-Jun-01)
Mapping Qtl Loci Affecting Growth and Disease Resistance to Avian Coccidiosis - (Abstract Only) - (30-Apr-01)
Analysis of Disease Resistance Associated Parameters in Broiler Chickens - (Abstract Only) - (01-Sep-00)
Kinetic Differences in Intestinal and Systemic Inferferon-Gamma and Antigen-Specific Antibodies in Chickens Experimentally Infected with Eimeria Maxima - (Peer Reviewed Journal) - (07-Jul-00)
Kinetic Differences in Intestinal and Systemic Interfon-Gamma and Antigen Specific Antibodies in Chickens Experimentally Infected with Eimeria Maxima - (Abstract Only) - (03-Apr-00)
Analysis of Disease Resistance Associated Parameters. Analysis of Disease Resistance Associated Parameters in Broiler Chickens Challenged with Eimeria Maxima - (Peer Reviewed Journal) - (01-Apr-00)
Marek's Disease Challenge of An F2 Broiler Chicken Population - (Abstract Only) - (21-Feb-00)
Kinetic Differences in Intestinal and Systemic Inferteron-Gamma and Antigen-Specific Antibodies in Chckens Experimentally Infected with Eimeriamaxima - (Peer Reviewed Journal) - (01-Feb-00)
Screening for Heterozygous Chickens. Screening for Highly Heterozygous Chickens in Outbred Commercial Broiler Lines to Increase Detection Power for Mapping Quantitative Trait Loci - (Peer Reviewed Journal) - (20-Jan-00)
Screening for Highly Heterozygous Chickens in Outbred Commercial Broiler Lines to Increase Detection Power for Mapping Quantitative Trait Loci - (Abstract Only) - (01-Dec-99)
ARS News Articles
Last Modified: 10/20/2014