Publications

Factors influencing the attenuation of serotype 1 Marek's disease virus by serial cell culture passage, and evaluation of attenuated strains for protection and replication - (Peer Reviewed Journal)

Dudnikova, E., Vlasov, A., Norkina, S., Kireev, D., Witter, R.L. 2009. Factors Influencing the Attenuation of Serotype 1 Marek's Disease Virus by Serial Cell Culture Passage and Evaluation of Attenuated Strains for Protection and Replication. Avian Diseases. 53(1):63-72.

Frequency of multiple serotype 1 Marek's disease virus strains in feather follicle epithelium and tumor cells following superinfection - (Abstract)

Dunn, J.R., Witter, R.L., Silva, R.F., Lee, L.F. 2008. Frequency of multiple serotype 1 Marek's disease virus strains in feather follicle epithelium and tumor cells following superinfection [abstract]. American Veterinary Medical Association Convention Notes. 145th AVMA Annual Convention, July 19-22, 2008, New Orleans, LA. 2008 CD-ROM.

A comparison between Marek's disease virus production in feather pulp versus feather follicle epithelium (FFE) - (Abstract)

Dunn, J.R., Finlay, J.B., Witter, R.L., Silva, R.F. 2007. A comparison between Marek's disease virus production in feather pulp versus feather follicle epithelium (FFE) [abstract]. American Association of Avian Pathologists/American Veterinary Medical Association Abstract. p. 40.

Reticuloendotheliosis - (Book/Chapter)

Fadly, A.M., Zavala, G., Witter, R.L. 2008. Reticuloendotheliosis. In: Saif, Y.M., Fadly, A.M., Glisson, J.R., McDougald, L.R., Nolan, L.K., Swayne, D.E., editors. Diseases of Poultry. 12th edition. Ames, IA: Iowa State University Press. p. 568-588.

Evaluation of Marek's disease field isolates by the "best fit" pathotyping assay - (Peer Reviewed Journal)

Dudnikova, E., Norkina, S., Vlasov, A., Slobodchuk, A., Lee, L.F., Witter, R.L. 2007. Evaluation of Marek's disease field isolates by the "best fit" pathotyping assay. Avian Pathology. 36(2):135-143.

Putative evidence that genes outside the MHC have a significant influence on efficacy of Marek's disease vaccine - (Abstract)

Zhang, H.M., Dunn, J.R., Witter, R.L., Heidari, M., Bacon, L.D., Cui, Y., Song, J., Cheng, H.H. 2007. Putative evidence that genes outside the MHC have a significant influence on efficacy of Marek's disease vaccine [abstract]. Plant and Animal Genome VX Conference Abstracts. Paper #107. p. 128.

METHODS TO DISTINQUISH SELECTED SEROTYPE 1 MDV IN DUALLY INFECTED CHICKENS - (Abstract)

Dunn, J.R., Gross, S.B., Witter, R.L., Silva, R.F., Lee, L.F. 2006. Methods to distinquish selected serotype 1 MDV in dual-infected chickens [abstract]. 4th International Workshop on Molecular Pathogenesis of Marek's Disease Virus. p. 39.

THE THRESHOLD OF GENETIC SUSCEPTIBILITY TO MAREK'S DISEASE - (Abstract)

Zhang, H.M., Dunn, J.R., Heidari, M., Witter, R.L., Kulkarni, G., Bacon, L.D. 2006. The threshold of genetic susceptibility to Marek's disease [abstract]. 4th International Workshop on Molecular Pathogenesis of Marek's Disease Virus. p. 33.

Application of the "best fit" pathotyping assay for evaluation of Russian isolates of Marek's disease virus - (Abstract)

Dudnikova, E., Norkina, S., Vlasov, A., Slobodchuk, A., Lee, L.F., Witter, R.L. 2006. Application of the "best fit" pathotyping assay for evaluation of Russian isolates of Marek's disease virus. 4th International Workshop on Molecular Pathogenesis of Marek's Disease Virus. p. 40.

A COMPARISON BETWEEN MDV PRODUCTION IN FEATHER PULP VERSUS FEATHER FOLLICLE EPITHELIUM (FFE) - (Abstract)

Finlay, J.B., Dunn, J.R., Witter, R.L., Silva, R.F. 2006. A comparison between MDV production in feather pulp versus feather follicle epithelium (FFE)[abstract]. 2006 Merck/Merial National Veterinary Scholar Symposium. Veterinary Medicine and Biomedical Science: Creating the Gumbo of Progress. p. 97.

PREVENTION AND CONTROL OF RETICULOENDOTHELIOSIS VIRUS INFECTION: RATIONALE AND STRATEGIES - (Review Article)

Witter, R.L. 2006. Prevention and control of reticuloendotheliosis virus infection: rationale and strategies. American Association of Avian Pathologists. In: A.A.A.P. Symposium Program, "Impact of Subclinical Immunosuppression on Poultry Production", July 2006, Honolulu, Hawaii. p. 81-89.

METHODS TO DISTINGUISH SELECTED SEROTYPE 1 MDV IN DUALLY INFECTED CHICKENS - (Abstract)

Dunn, J.R., Gross, S.B., Witter, R.L., Silva, R.F., Lee, L.F. 2006. Methods to distinguish selected serotype 1 MDV in dually infected chickens [abstract]. American Veterinary Medical Association and American Association of Avian Pathologists Scientific Program. p. 73.

SUSCEPTIBILITY OF ADULT CHICKENS, WITH AND WITHOUT PRIOR VACCINATION, TO CHALLENGE WITH MAREK'S DISEASE VIRUS - (Peer Reviewed Journal)

Witter, R.L., Gimeno, I.M. 2006. Susceptibility of adult chickens, with and without prior vaccination, to challenge with Marek's disease virus. Avian Diseases. 50(3):354-365.

ONCORNAVIRUSES: LEUKOSIS/SARCOMA AND RETICULOENDOTHELIOSIS - (Book/Chapter)

Fadly, A.M., Witter, R.L., Hunt, H.D. 2008. Oncornaviruses: leukosis/sarcomas and reticuloendotheliosis. In: Dufour-Zavala, L., Swayne, D.E., Glisson, J.R., Pearson, J.E., Reed, W.M., Jackwood, M.W., Woolcock, P.R., editors. A Laboratory Manual for the Isolation, Identification and Characterization of Avian Pathogens. 5th edition. Jacksonville, FL: American Association of Avian Pathologists. p. 164-172.

MAREK'S DISEASE VIRUS MEQ TRANSFORMS CHICKEN CELLS VIA THE V-JUN TRANSCRIPTIONAL CASCADE: A CONVERGING TRANSFORMING PATHWAY FOR AVIAN ONCOVIRUSES - (Peer Reviewed Journal)

Levy, A.M., Gilad, O., Xia, L., Izumiya, Y., Choi, J., Tsalenko, A., Yakhini, Z., Witter, R.L., Lee, L.F., Cardona, C., Kung, H. 2005. Marek's disease virus MEQ transforms chicken cells via the v-jun transcriptional cascade: a converging transforming pathway for avian oncoviruses. Proceedings of the National Academy of Sciences. 102:14831-14836.

DIFFERENTIAL DIAGNOSIS OF LYMPHOID AND MYELOID TUMORS IN THE CHICKEN - (Review Article)

Witter, R.L., Gimeno, I.M., Fadly, A.M. 2005. AAAP Continuing Education Program Slide Study Sets: Differential diagnosis of lymphoid and myeloid tumors in the chickens [CD-ROM]. Set 26 & 27. Athens, Georgia: American Association of Avian Pathologists (AAAP).

NOVEL CRITERIA FOR THE DIAGNOSIS OF MDV INDUCED LYMPHOMAS - (Peer Reviewed Journal)

Gimeno, I.M., Witter, R.L., Fadly, A.M., Silva, R.F. 2005. Novel criteria for the diagnosis of Marek's disease virus-induced lymphomas. Avian Pathology. 34(4):332-340.

CLASSIFICATION OF MAREK'S DISEASE VIRUSES ACCORDING TO PATHOTYPE--PHILOSOPHY AND METHODOLOGY - (Peer Reviewed Journal)

Witter, R.L., Calnek, B.W., Buscaglia, C., Gimeno, I.M., Schat, K.A. 2005. Classification of Marek's disease viruses according to pathotype--philosophy and methodology. Avian Pathology. 34:75-90.

THE PP38 GENE OF MAREK'S DISEASE VIRUS (MDV) IS NECESSARY FOR CYTOLYTIC INFECTION OF B CELLS AND THE MAINTENANCE OF THE TRANSFORMED STATE BUT NOT FOR CYTOLYTIC ... SPREAD OF MDV. - (Peer Reviewed Journal)

Gimeno, I.M., Witter, R.L., Hunt, H.D., Reddy, S.M., Lee, L.F., Silva, R.F. 2005. The pp38 gene of Marek's disease virus (MDV) is necessary for cytolytic infection of B cells and maintenance of the transformed state but not for cytolytic infection of the feather follicle epithelium and horizontal spread of MDV. Journal of Virology. 79(7):4545-4549.

MAREK'S DISEASE: THE CONTINUING STRUGGLE BETWEEN PATHOGEN AND HOST - (Review Article)

Witter, R.L. 2005. Marek's disease: the continuing struggle between pathogen and host. Review Article. Available: http://authors.elsevier.com/sd/article/S1090023304002199.

MAREK'S DISEASE - (Review Article)

Gimeno, I.M., Witter, R.L., Miles, A.M. 2005. AAAP Continuing Education Program Slide Study Sets: Marek's disease [CD-ROM]. Set 26 & 27. Athens, Georgia: American Association of Avian Pathologists (AAAP).

RETROVIRUSES AND MAREK'S DISEASE VIRUS - (Proceedings/Symposium)

Fadly, A.M., Witter, R.L., Crespo, R., Davidson, I., Hafez, H.M. 2004. Retroviruses and Marek's Disease virus. In: Emerging and Re-emerging Diseases. American Association of Avian Pathologists Symposium, July 25, 2004, Philadelphia, Pennsylvania. p. 33-36.

NOVEL METHODS TO DIAGNOSIS MAREK'S DISEASE - (Abstract)

Gimeno, I.M., Witter, R.L., Fadly, A.M., Silva, R.F. 2004. Novel methods to diagnosis Marek's Disease [abstract]. American Veterinary Medical Association. p. 59.

TOWARDS A UNIVERSAL PATHOTYPING METHODOLOGY FOR MAREK'S DISEASE VIRUS - (Abstract)

Witter, R.L., Calnek, B.W., Buscaglia, C., Gimeno, I.M., Schat, K.A. 2004. Towards a universal pathotyping methodology for Marek's disease virus [abstract]. International Marek's Disease Symposium Abstracts and Proceedings. Paper No. III-5.

MAREK'S DISEASE VIRUS ENCODED MEQ GENE IS INVOLVED IN TRANSFORMATION OF LYMPHOCYTES BUT DISPENSABLE FOR REPLICATION - (Peer Reviewed Journal)

Lupiani, B.M., Lee, L.F., Cui, X., Gimeno, I.M., Anderson, A., Morgan, R.W., Silva, R.F., Witter, R.L., Kung, H., Reddy, S. 2004. Marek's disease virus-encoded Meq gene is involved in transformation of lymphocytes but is dispensable for replication. Proceedings of the National Academy of Sciences. 101(32):11815-11820.

VIRUS-INDUCED NEOPLASTIC DISEASES OF TURKEYS: AN UPDATE - (Abstract)

Fadly, A.M., Witter, R.L., Crespo, R., Davidson, I., Hafez, H.M. 2004. Virus-induced neoplastic diseases of turkeys: an update [abstract]. 5th International Symposium on Turkey Diseases. p. 18.

VIRUS-INDUCED NEOPLASTIC DISEASES OF TURKEYS: AN UPDATE - (Proceedings/Symposium)

Fadly, A.M., Witter, R.L., Crespo, R., Davidson, I., Hafez, H.M. 2005. Virus-induced neoplastic diseases of turkeys: an update. In: Proceedings of the German Branch of the World Veterinary Poultry Association. 5th International Symposium on Turkey Diseases. p. 64-67.

SEROTYPE 1 VIRUSES MODIFIED BY BACKPASSAGE OR INSERTIONAL MUTAGENESIS: APPROACHING THE THRESHOLD OF VACCINE EFFICACY IN MAREK'S DISEASE - (Peer Reviewed Journal)

Witter, R.L., Kreager, K.S. 2004. Serotype 1 viruses modified by backpassage or insertional mutagenesis: approaching the threshold of vaccine efficacy in Marek's disease. Avian Diseases. 48:768-782.

A COMPARISON OF SEROLOGICAL AND VIROLOGICAL FINDINGS FROM AVIAN LEUKOSIS VIRUS, SUBGROUP J-AFFECTED FLOCKS AND NORMAL BROILER BREEDER FLOCKS - (Peer Reviewed Journal)

Malkinson, M., Banet-Noach, C., Davidson, I., Fadly, A.M., Witter, R.L. 2004. Comparison of serological and virological findings from subgroup J avian leukosis virus-infected neoplastic and non-neoplastic flocks in Israel. Avian Pathology. p. 281-287.

THE EFFICACY OF RECOMBINANT FOWLPOX VACCINE PROTECTION AGAINST MAREK'S DISEASE: ITS DEPENDENCE ON CHICKEN LINE AND B HAPLOTYPE - (Peer Reviewed Journal)

Lee, L.F., Bacon, L.D., Yoshida, S., Yanagida, N., Zhang, H., Witter, R.L. 2004. The efficacy of recombinant fowlpox vaccine protection against marek's disease: its dependence on chicken line and b haplotype. Avian Diseases. 48:129-137.

BIOCHARACTERISTICS SHARED BY HIGHLY PROTECTIVE VACCINES AGAINST MAREK'S DISEASE - (Peer Reviewed Journal)

Gimeno, I.M., Witter, R.L., Hunt, H.D., Reddy, S.M., Reed, W.M. 2003. Biocharacteristics shared by highly protective vaccines against Marek's disease. Avian Pathology. 33(1):59-68.

NEW TECHNIQUES FOR DIAGNOSIS OF MAREK'S DISEASE IN CHICKENS - (Proceedings/Symposium)

Shaw, G., Gimeno, I.M., Witter, R.L., Lee, L.F., Silva, R.F., Fadly, A.M. 2003. New techniques for diagnosis of Marek's disease in chickens. Annual Merck Merial Veterinary Scholars Symposium. p. 105.

ROLE OF THE GENE PP38 IN THE PATHOGENESIS OF MAREK'S DISEASE VIRUS - (Proceedings/Symposium)

Gimeno, I.M., Hunt, H.D., Witter, R.L., Neumann, U., Reddy, S., Silva, R.F. 2003. Role of the gene pp38 in the pathogenesis of marek's disease virus. World Veterinary Poultry Association Congress Proceedings. p. 101.

MAREK'S DISEASE - PAST SUCCESSES AND FUTURE CONCERNS - (Abstract)

WITTER, R.L. MAREK'S DISEASE - PAST SUCCESSES AND FUTURE CONCERNS. PROCEEDINGS OF NORTHEAST CONFERENCE ON AVIAN DISEASES. 2003. p. 1-2.

IMMUNOLOGICAL FEATURES OF SEROTYPE 1 MAREK'S DISEASE VIRUS VACCINES - (Abstract)

Gimeno, I.M., Witter, R.L., Hunt, H.D., Reed, W.M. 2002. Immunological features of serotype 1 marek's disease virus vaccines [abstract]. American Veterinary Medical Association. p. 19.

CASE REPORT: DETERMINING THE ETIOLOGY OF UNUSUAL TUMORS IN CHICKENS - (Abstract) - (13-Jul-02)

INDUCTION OF STRONG PROTECTION BY VACCINATION WITH PARTIALLY ATTENUATED SEROTYPE 1 MAREK'S DISEASE VIRUSES - (Peer Reviewed Journal)

Witter, R.L. 2002. Induction of strong protection by vaccination with partially attenuated serotype 1 marek's disease viruses. Avian Diseases. 46:925-937.

NEUROPATHOTYPING: A NEW SYSTEM TO CLASSIFY MAREK'S DISEASE VIRUS - (Peer Reviewed Journal)

Gimeno, I.M., Witter, R.L., Neumann, U. 2002. Neuropathotyping: a new system to classify marek's disease virus. Avian Diseases. 46:909-918.

VACCINATION OF POULTRY: THE SPECIAL CASE OF MAREK'S DISEASE HERPESVIRUS-INDUCED LYMPHOMAS - (Abstract) - (06-May-02)

SUSCEPTIBILITY OF ADULT CHICKENS TO MAREK'S DISEASE - (Proceedings/Symposium) - (01-May-02)