Projects

GENETIC AND BIOLOGICAL DETERMINANTS OF AVIAN TUMOR VIRUS PATHOGENICITY, TRANSMISSION, AND EVOLUTION Appropriated (D)   Accession Number: 422136

COMPARISON OF TRADITIONAL AND SEQUENCED-BASED PATHOTYPING OF MAREK'S DISEASE VIRUS FIELD STRAINS Trust (T)   Accession Number: 423880

Publications (Clicking on the reprint icon will take you to the publication reprint.)

The influence of host genetics on Marek's disease virus evolution - (Peer Reviewed Journal) - (28-Dec-12)

Current status of Marek’s disease in the United States & worldwide based on a questionnaire survey - (Peer Reviewed Journal) - (13-Dec-12)

Positive correlation between replication rate and pathotype of Marek’s disease virus strains in maternal antibody negative chickens - (Abstract Only)

Auten, K.M., Heidari, M., Dunn, J.R. 2012. Positive correlation between replication rate and pathotype of Marek’s disease virus strains in maternal antibody negative chickens. Meeting Abstract. Merial-NIH National Veterinary Scholar Sympsoium. Comparative Medicine: The Key to Translation, August 2-5, 2012, Loveland, Colorado.

Current status of Marek's disease in the united states and worldwide - (Abstract Only)

Dunn, J.R., Gimeno, I. 2012. Current status of Marek's disease in the united states and worldwide [abstract]. 9th International Symposium on Marek's Disease and Avian Herpesviruses, June 24-28, 2012, Freie Universitat Berlin. p. 53.

Marek’s disease virus evolution in specific MHC haplotypes. - (Abstract Only)

Hunt, H.D., Dunn, J.R. 2012. Marek’s disease virus evolution in specific MHC haplotypes [abstract]. 9th International Symposium on Marek's Disease and Avian Herpesviruses, June 24-28, 2012, Freie Universitat Berlin. p. 41.

Differential genetic variation of chickens and MD vaccine protective efficacy - (Abstract Only)

Xie, Q., Chang, S., Ernst, C.W., Dunn, J.R., Song, J., Zhang, H. 2012. Differential genetic variation of chickens and MD vaccine protective efficacy [abstract]. 9th International Symposium on Marek's Disease and Avian Herpesviruses, June 24-28, 2012, Freie Universitat Berlin. p.36.

Use of Polymerase chain reaction (PCR) in diagnosis of Marek’s disease and reticuloendotheliosis in formalin-fixed, paraffin-embedded tumorous tissues - (Abstract Only)

Fadly, A.M., Cao, W., Fulton, R.M., Mays, J.K., Dunn, J.R., Silva, R.F. 2012. Use of Polymerase chain reaction (PCR) in diagnosis of Marek’s disease and reticuloendotheliosis in formalin-fixed, paraffin-embedded tumorous tissues. Meeting Abstract. Paper No. 12498.

Ability of MEQ-deleted MDV vaccine candidates to adversely affect lymphoid organs and chicken weight gain - (Peer Reviewed Journal)

Dunn, J.R., Silva, R.F. 2012. Ability of MEQ-deleted MDV vaccine candidates to adversely affect lymphoid organs and chicken weight gain. Avian Diseases. 56:494-500.

Host genetic resistance sustains HVT protective efficacy comparable to CV1988/Rispens' in lines of chickens relatively resistant to Marek's disease - (Abstract Only)

Zhang, H., Chang, S., Dunn, J.R., Heidari, M., Song, J., Fulton, J. 2012. Host genetic resistance sustains HVT protective efficacy comparable to CV1988/Rispens' in lines of chickens relatively resistant to Marek's disease. Plant and Animal Genome Conference. Available: https://pag.confex.com/pag/xx/webprogram/Paper3980.html.

Competition between two virulent Marek's disease virus strains in vivo - (Peer Reviewed Journal)

Dunn, J.R., Silva, R.F., Lee, L.F., Witter, R.L. 2012. Competition between two virulent Marek's disease virus strains in vivo. Avian Pathology. 41(3):267-275. Available: http://dx.doi.org/10.1080/03079457.2012.677804.

Vaccine by chicken line interaction alters the protective efficacy against challenge with a very virulent plus strain of Marek's disease virus in white leghorn chickens - (Peer Reviewed Journal)

Chang, S., Dunn, J.R., Heidari, M., Lee, L.F., Ernst, C.W., Song, J., Zhang, H. 2012. Vaccine by chicken line interaction alters the protective efficacy against challenge with a very virulent plus strain of Marek's disease virus in white leghorn chickens. World Journal of Vaccines. 2(1):1-11. Available: http://www.scirp.org/journal/wjv/.

Research update: Avian Disease and Oncology Laboratory avian tumor viruses - (Proceedings)

Fadly, A.M., Cheng, H.H., Dunn, J.R., Heidari, M., Hunt, H.D., Lee, L.F., Silva, R.F., Zhang, H. 2012. Research update: Avian Disease and Oncology Laboratory avian tumor viruses. In: Proceedings for the 115th Annual Meeting of the United States Animal Health Association, September 29-October 5, 2011, Buffalo, New York. 462-464.

Correlation between Marek's disease virus replication rates and pathotype based on fifteen virus strains - (Abstract Only)

Dunn, J.R. 2011. Correlation between Marek's disease virus replication rates and pathotype based on fifteen virus strains [CD-ROM]. American Veterinary Medical Association (AVMA) Convention, July 16-19, 2011, St. Louis, Missouri. Paper No. 11066.

Appraisal of experimental and commercial Marek's disease vaccines to induce bursal and thymic atrophy - (Abstract Only)

Silva, R.F., Dunn, J.R. 2011. Appraisal of experimental and commercial Marek's disease vaccines to induce bursal and thymic atrophy [CD-ROM]. American Veterinary Medical Association (AVMA) Convention, July 16-19, 2011, St. Louis, Missouri. Paper No. 11069.

Detection of lymphoid leukosis tumors in white leghorn chickens of line ALV6 that is resistant to subgroups A and E avian leukosis virus and maintained under specific pathogen-free conditions - (Abstract Only)

Fadly, A.M., Mays, J.K., Dunn, J.R., Kulkarni, G. 2011. Detection of lymphoid leukosis tumors in white leghorn chickens of line ALV6 that is resistant to subgroups A and E avian leukosis virus and maintained under specific pathogen-free conditions [CD-ROM]. American Veterinary Medical Association (AVMA) Convention, July 16-19, 2011, St. Louis, Missouri. Paper No. 11129.

A comparative evaluation of the protective efficacy of rMd5-delta-Meq and CV1988/Rispens against a vv+ strain of Marek's disease virus infection in a series of recombinant congenic strains of white leghorn chickens - (Peer Reviewed Journal)

Chang, S., Ding, Z., Dunn, J.R., Lee, L.F., Heidari, M., Song, J., Ernst, C.W., Zhang, H. 2011. A comparative evaluation of the protective efficacy of rMd5-delta-Meq and CV1988/Rispens against a vv+ strain of Marek's disease virus infection in a series of recombinant congenic strains of white leghorn chickens. Avian Diseases. 55(3):384-390.

The protective efficacy of rMd5deltaMeq against challenge with a very virulent plus strain of MDV in relatively resistant lines of chickens - (Abstract Only)

Chang, S., Dunn, J.R., Lee, L.F., Heidari, M., Song, J.Z., Ernst, C.W., Zhang, H.M. 2011. The protective efficacy of rMd5deltaMeq against challenge with a very virulent plus strain of MDV in relatively resistant lines of chickens [abstract]. Poultry Science Association/American Association of Avian Pathologists Abstracts, July 16-19, 2011, St. Louis, Missouri. p. 124.

Identifying genetic determinants of host resistance to Marek's disease - (Abstract Only)

Zhang, H., Chang, S., Dunn, J.R., Luo, J., Song, J. 2011. Identifying genetic determinants of host resistance to Marek's disease [abstract]. International Plant and Animal Genome Conference PAG XIX, January 15-19, 2011, San Diego, California. Paper #W466. Available: http://www.intl-pag.org/.

Serial Transfer of a Transplantable Tumor: Implications for Marek's Vaccine Mechanisms - (Peer Reviewed Journal)

Hunt, H.D., Dunn, J.R. 2011. Serial transfer of a transplantable tumor: implications for Marek's vaccine mechanisms. Avian Diseases. 55(2):293-301.

Avian Disease and Oncology Laboratory (ADOL) research update - (Proceedings)

Fadly, A.M., Cheng, H.H., Dunn, J.R., Heidari, M., Hunt, H.D., Lee, L.F., Silva, R.F., Zhang, H. 2011. Avian Disease and Oncology Laboratory (ADOL) research update. Proceedings One Hundred and Fourteenth Annual Meeting of the United States Animal Health Association (USAHA), November 11-17, 2010, Minneapolis, Minnesota. p. 528-530.

Mortality of one-week-old chickens during naturally occurring Marek's disease virus infection - (Peer Reviewed Journal)

Carvallo, F.R., French, R.A., Gilbert-Marcheterre, K., Risatti, G., Dunn, J.R., Forster, F., Kiupel, M., Smyth, J.A. 2011. Mortality of one-week-old chickens during naturally occurring Marek's disease virus infection. Veterinary Pathology. 48(5):993-998.

Potential Evidence of a Unique Marek's Disease Virus Strain Circulating in Pennsylvania - (Abstract Only)

Dunn, J.R., Gingerich, E. 2010. Potential evidence of a unique Marek's disease virus strain circulating in Pennsylvania [abstract]. In: 5th International Workshop on the Molecular Pathogenesis of Marek's Disease Virus and 1st Symposium on Avian Herpesviruses, October 17-20, 2010, Athens, Georgia, p. 103.`

MDV-Vectored Vaccine for Infectious Laryngotracheitis - (Abstract Only)

Silva, R.F., Hunt, H.D., Dunn, J.R. 2010. MDV-vectored vaccine for infectious laryngotracheitis [abstract]. In: 5th International Workshop on the Molecular Pathogenesis of Marek’s Disease Virus and 1st Symposium on Avian Herpesviruses, October 17-20, 2010, Athens, Georgia, p. 117.

Low Dose Vaccination Revealed An Interaction Between Vaccine and Chicken Line Affecting Protective Efficacy - (Abstract Only)

Zhang, H., Chang, S., Dunn, J.R., Heidari, M., Lee, L.F. 2010. Low dose vaccination revealed an interaction between vaccine and chicken line affecting protective efficacy [abstract]. In: 5th International Workshop on the Molecular Pathogenesis of Marek's Disease Virus and 1st Symposium on Avian Herpesviruses, October 17-20, 2010, Athens, Georgia, p. 129.

Diagnosis of Marek's Disease From a Japanese Quail (Coturnix Japonica) Using Paraffin-embedded Liver - (Abstract Only)

Dunn, J.R., Southard, T., Cooper, C., Kiupel, M., Witter, R.L. 2010. Diagnosis of Marek's Disease From a Japanese Quail (Coturnix Japonica) Using Paraffin-embedded Liver [abstract]. In: American Association of Avian Pathologists Symposium and Scientific Program, August 1-4, 2010, Atlanta, Georgia. Paper No. 9389.

Genetics and Vaccine Efficacy: Host Genetic Variation Affecting Marek's Disease Vaccine Efficacy in White Leghorn Chickens - (Peer Reviewed Journal)

Chang, S., Dunn, J.R., Heidari, M., Lee, L.F., Song, J., Ernst, C.W., Ding, Z., Bacon, L.D., Zhang, H. 2010. Genetics and Vaccine Efficacy: Host Genetic Variation Affecting Marek's Disease Vaccine Efficacy in White Leghorn Chickens. Poultry Science. 89(10):2083-2091.

The Effect of the Time Interval Between Exposures On the Susceptibility of Chickens to Superinfection with Marek Disease Virus - (Peer Reviewed Journal)

Dunn, J.R., Witter, R.L., Silva, R.F., Lee, L.F., Finlay, J., Marker, B.A., Kaneene, J.B., Fulton, R.M., Fitzgerald, S.D. 2010. The Effect of the Time Interval Between Exposures on the Susceptibility of Chickens to Superinfection with Marek Disease Virus. Avian Diseases. 54(3):1038-1049.

Genome-Wide SNP Association Analysis for Loci Conferring Marek's Disease - (Abstract Only)

Chang, S., Dunn, J.R., Heidari, M., Mitra, A., Song, J., Zhang, H. 2010. Genome-wide SNP association analysis for loci conferring Marek's disease [abstract]. In: 32nd Conference of the International Society for Animal Genetics Program and Abstract Book, July 26-30, 2010, Edinburgh, Scotland. Page No. 5088.

A MEQ Deleted Marek's Disease Virus Cloned as a Bacterial Artificial Chromosome is a Highly Efficacious Vaccine - (Peer Reviewed Journal)

Silva, R.F., Dunn, J.R., Cheng, H.H., Niikura, M. 2010. A MEQ-Deleted Marek's Disease Virus Cloned as a Bacterial Artificial Chromosome Is a Highly Efficacious Vaccine. Avian Diseases. 54(2):862-869.

Virus Competition for Shedding and Tumor Formation Over Time in Marek's Disease Virus Dual-infected Chickens - (Abstract Only)

Dunn, J.R., Witter, R.L., Silva, R.F., Lee, L.F., Fitzgerald, S.D., Kaneene, J.B., Fulton, R.M. 2009. Virus Competition for Shedding and Tumor Formation Over Time in Marek's Disease Virus Dual-infected Chickens [abstract]. In: 146th American Veterinary Medical Association Convention Notes, July 11-14, 2009, Seattle, Washington. Paper No. 7655.

Non-MHC genomic variation affecting Marek’s disease resistance and vaccine protective efficiency - (Abstract Only)

Chang, S., Dunn, J.R., Heidari, M., Lee, L.F., Song, J., Dodgson, J., Ding, Z., Zhang, H. 2009. Non-MHC Genomic Variation Affecting Marek’s Disease Resistance and Vaccine Protective Efficiency [abstract]. International Plant and Animal Genome XVII Conference, January 9-14, 2009, San Diego, California. p. 526.

Protective efficacy of a MEQ deleted BAC clone of Marek's disease virus - (Abstract Only)

Silva, R.F., Lee, L.F., Heidari, M., Dunn, J.R. 2008. Protective efficacy of a MEQ deleted BAC clone of Marek's disease virus [abstract]. American Veterinary Medical Association Convention Notes. 145th AVMA Annual Convention, July 19-22, 2008, New Orleans, LA. 2008 CD-ROM.

Frequency of multiple serotype 1 Marek's disease virus strains in feather follicle epithelium and tumor cells following superinfection - (Abstract Only)

Dunn, J.R., Witter, R.L., Silva, R.F., Lee, L.F. 2008. Frequency of multiple serotype 1 Marek's disease virus strains in feather follicle epithelium and tumor cells following superinfection [abstract]. American Veterinary Medical Association Convention Notes. 145th AVMA Annual Convention, July 19-22, 2008, New Orleans, LA. 2008 CD-ROM.

Genetic bases for Marek's disease resistance - (Abstract Only)

Zhang, H., Heidari, M., Dunn, J.R., Yu, Y., Song, J. 2008. Genetic bases for Marek's disease resistance. Plant and Animal Genome Conference Proceedings. p. 96.

A comparison between Marek's disease virus production in feather pulp versus feather follicle epithelium (FFE) - (Abstract Only)

Dunn, J.R., Finlay, J.B., Witter, R.L., Silva, R.F. 2007. A comparison between Marek's disease virus production in feather pulp versus feather follicle epithelium (FFE) [abstract]. American Association of Avian Pathologists/American Veterinary Medical Association Abstract. p. 40.

The effect of vaccination on Marek's disease virus shedding - (Abstract Only)

Silva, R.F., El-Gohary, A., Dunn, J.R. 2007. The effect of vaccination on Marek's disease virus shedding [abstract]. American Association of Avian Pathologists/American Veterinary Medical Association Abstract. p. 39.

MDV-induced skin leukosis in scaleless chickens: tumor development in the absence of feather follicles - (Peer Reviewed Journal)

Heidari, M., Fitzgerald, S.D., Zhang, H.M., Silva, R.F., Lee, L.F., Dunn, J.R. 2007. MDV-induced skin leukosis in scaleless chickens: tumor development in the absence of feather follicles. Avian Diseases. 51(3):713-718.

Putative evidence that genes outside the MHC have a significant influence on efficacy of Marek's disease vaccine - (Abstract Only)

Zhang, H.M., Dunn, J.R., Witter, R.L., Heidari, M., Bacon, L.D., Cui, Y., Song, J., Cheng, H.H. 2007. Putative evidence that genes outside the MHC have a significant influence on efficacy of Marek's disease vaccine [abstract]. Plant and Animal Genome VX Conference Abstracts. Paper #107. p. 128.

METHODS TO DISTINQUISH SELECTED SEROTYPE 1 MDV IN DUALLY INFECTED CHICKENS - (Abstract Only)

Dunn, J.R., Gross, S.B., Witter, R.L., Silva, R.F., Lee, L.F. 2006. Methods to distinquish selected serotype 1 MDV in dual-infected chickens [abstract]. 4th International Workshop on Molecular Pathogenesis of Marek's Disease Virus. p. 39.

THE THRESHOLD OF GENETIC SUSCEPTIBILITY TO MAREK'S DISEASE - (Abstract Only)

Zhang, H.M., Dunn, J.R., Heidari, M., Witter, R.L., Kulkarni, G., Bacon, L.D. 2006. The threshold of genetic susceptibility to Marek's disease [abstract]. 4th International Workshop on Molecular Pathogenesis of Marek's Disease Virus. p. 33.

A COMPARISON BETWEEN MDV PRODUCTION IN FEATHER PULP VERSUS FEATHER FOLLICLE EPITHELIUM (FFE) - (Abstract Only)

Finlay, J.B., Dunn, J.R., Witter, R.L., Silva, R.F. 2006. A comparison between MDV production in feather pulp versus feather follicle epithelium (FFE)[abstract]. 2006 Merck/Merial National Veterinary Scholar Symposium. Veterinary Medicine and Biomedical Science: Creating the Gumbo of Progress. p. 97.

METHODS TO DISTINGUISH SELECTED SEROTYPE 1 MDV IN DUALLY INFECTED CHICKENS - (Abstract Only)

Dunn, J.R., Gross, S.B., Witter, R.L., Silva, R.F., Lee, L.F. 2006. Methods to distinguish selected serotype 1 MDV in dually infected chickens [abstract]. American Veterinary Medical Association and American Association of Avian Pathologists Scientific Program. p. 73.