Projects

INTERVENTION STRATEGIES TO CONTROL AND PREVENT ENTERIC VIRAL DISEASES OF POULTRY Appropriated (D)   Accession Number: 422701

Publications (Clicking on the reprint icon will take you to the publication reprint.)

NDV HN gene C-terminal extension is not the determinant of the enteric tropism but influences the virus virulence - (Abstract Only) - (18-Jan-13)

Passive antibody transfer in chickens to model maternal antibody after avian influenza vaccination - (Peer Reviewed Journal)

Faulkner, O.B., Estevez, C., Yu, Q., Suarez, D.L. 2013. Passive antibody transfer in chickens to model maternal antibody after avian influenza vaccination. Veterinary Immunology and Immunopathology. 152(3-4):341-347.

Avian metapneumovirus in the USA - (Review Article)

Yu, Q. 2012. Avian metapneumovirus in the USA. Review Article. 2012 CDROM.

Reverse genetics of avian metapneumoviruses - (Abstract Only) - (01-Oct-12)

Generation and characterization of a recombinant Newcastle disease virus expressing the red fluorescent protein for use in co-infection studies - (Peer Reviewed Journal)

Li, J., Hu, H., Yu, Q., Diel, D.G., Li, D., Miller, P.J. 2012. Generation and characterization of a recombinant Newcastle disease virus expressing the red fluorescent protein for use in co-infection studies. Virology Journal. 9:227. DOI 10.1186/1743-422X-9-227.

Development of Recombinant Newcastle Disease Viruses Expressing the Glycoprotein (G) of Avian Metapneumovirus as Bivalent Vaccines - (Abstract Only)

Yu, Q., Roth, J.P., Hu, H., Estevez, C., Zsak, L. 2012. Development of Recombinant Newcastle Disease Viruses Expressing the Glycoprotein (G) of Avian Metapneumovirus as Bivalent Vaccines [abstract]. Meeting Abstract. CDROM.

Characteristics of pigeon paramyxovirus serotype-1 isolates (PPMV-1) from the Russian Federation from 2001 to 2009 - (Peer Reviewed Journal) - (01-Aug-12)

Generation of recombinant newcastle disease viruses, expressing the glycoprotein (G) of avian metapneumovirus, subtype A, or B, for use as bivalent vaccines - (Proceedings)

Yu, Q., Roth, J.P., Hu, H., Estevez, C., Zsak, L. 2012. Generation of recombinant newcastle disease viruses, expressing the glycoprotein (G) of avian metapneumovirus, subtype A, or B, for use as bivalent vaccines. International Symposium on Avian Corona and Pneumoviruses and Complicating Pathogens. CDROM.

Avian Metapneumovirus Molecular Biology and Development of Genetically Engineered Vaccines - (Review Article)

Hu, H., Zhao, W., Yu, Q. 2012. Avian metapneumovirus molecular biology and development of genetically engineered vaccines. China Poultry. 34(12):1-5.

Biochemical characterization of the small hydrophobic protein of avian metapneumovirus - (Peer Reviewed Journal)

Deng, Q., Song, M., Demers, A., Weng, Y., Lu, W., Wang, D., Kaushik, R.S., Yu, Q., Li, F. 2012. Biochemical characterization of the small hydrophobic protein of avian metapneumovirus. Virus Research. 167:297-301.

Evaluation of a LaSota strain-based recombinant Newcastle disease virus (NDV) expressing the glycoprotein (G) of avian metapneumovirus (aMPV) subgroup A or B as a bivalent vaccine in turkeys - (Abstract Only)

Yu, Q., Roth, J.P., Hu, H., Estevez, C., Zsak, L. 2012. Evaluation of a LaSota strain-based recombinant Newcastle disease virus (NDV) expressing the glycoprotein (G) of avian metapneumovirus (aMPV) subgroup A or B as a bivalent vaccine in turkeys [abstract]. Meeting Abstract. CDROM.

Development of a Recombinant Newcastle Disease Virus VG/GA Strain Infectious Clone as an Enterotropic Vaccine Vector - (Abstract Only) - (02-Dec-11)

Thermal inactivation of avian viral pathogens in an effluent treatment system within a biosafety level 2 and 3 enhanced facility - (Peer Reviewed Journal)

Chmielewski, R.A., Day, J.M., Spatz, S.J., Yu, Q., Gast, R.K., Zsak, L., Swayne, D.E. 2011. Thermal inactivation of avian viral pathogens in an effluent treatment system within a biosafety level 2 and 3 enhanced facility. Applied Biosafety. 16(4):206-217.

Generation and characterization of a LaSota strain recombinant Newcastle disease virus expressing the red fluorescent protein for use in co-infection studies - (Abstract Only)

Miller, P.J., Hu, H., Yu, Q., Diel, D.G., Li, J. 2012. Generation and characterization of a LaSota strain recombinant Newcastle disease virus expressing the red fluorescent protein for use in co-infection studies [abstract]. Meeting Abstract. 50:378-387.

Exchange of Newcastle disease virus fusion and hemagglutinin-neuraminidase genes into a vaccine backbone: effects on virulence - (Abstract Only)

Cardenas Garcia, S., Susta, L., Diel, D.G., Decanini, E.L., Absalon, A., Brown, C., Yu, Q., Miller, P.J., Afonso, C.L. 2012. Exchange of Newcastle disease virus fusion and hemagglutinin-neuraminidase genes into a vaccine backbone: effects on virulence . Meeting Abstract. 50:378-387.

Generation and evaluation of a recombinant Newcastle disease virus expressing the glycoprotein (G) of avian metapneumovirus subgroup C as a bivalent vaccine in turkeys - (Peer Reviewed Journal)

Hu, H., Roth, J.P., Estevez, C., Liu, B., Zsak, L., Yu, Q. 2011. Generation and evaluation of a recombinant Newcastle disease virus expressing the glycoprotein (G) of avian metapneumovirus subgroup C as a bivalent vaccine in turkeys. Vaccine. 29(47):8624-33.

Topology and cellular localization of the small hydrophobic protein of avian metapneumovirus - (Peer Reviewed Journal)

Deng, Q., Weng, Y., Lu, W., Demers, A., Song, M., Wang, D., Yu, Q., and Li, F. 2011. Topology and cellular localization of the small hydrophobic protein of avian metapneumovirus. Virus Research. 160:102-107.

Development and characterization of a LaSota strain recombinant Newcastle disease virus expressing the red fluorescent protein for use in co-infection studies - (Abstract Only)

Li, J., Hu, H., Yu, Q., Miller, P.J. 2011. Development and characterization of a LaSota strain recombinant Newcastle disease virus expressing the red fluorescent protein for use in co-infection studies [abstract]. 1st International Avian Respiratory Disease Conference, May 15-18, 2011, Athens, Georgia. p. 53.

Generation and evaluation of a LaSota strain-based recombinant Newcastle disease virus (NDV) expressing the glycoprotein (G) of avian metapneumovirus subgroup C (aMPV-C) as a bivalent vaccine - (Abstract Only) - (01-Feb-11)

Deletion of the M2-2 Gene from Avian Metapneumovirus Subgroup C (aMPV-C) Impairs Virus Replication and Immunogenicity in Turkeys - (Abstract Only) - (01-Feb-11)

The cellular endosomal sorting complex required for transport pathway is not involved in avian metapneumovirus budding in a virus-like-particle expression system. - (Peer Reviewed Journal)

Weng, Y., Lu, W., Harmon, A., Xiang, X., Deng, Q., Song, M., Wang, D., Yu, Q., Li, F. 2011. The cellular endosomal sorting complex required for transport pathway is not involved in avian metapneumovirus budding in a virus-like-particle expression system.. Journal of General Virology. 92:1205-1213.

Deletion of the M2-2 gene from avian metapneumovirus subgroup C impairs virus replication and immunogenicity in turkeys - (Peer Reviewed Journal)

Yu, Q., Estevez, C., Roth, J.P., Hu, H., Zsak, L. 2011. Deletion of the M2-2 gene from avian metapneumovirus subgroup C impairs virus replication and immunogenicity in turkeys. Virus Genes. 42:339-346.

A single amino acid substitution in the hemagglutinin-neuraminidase protein of Newcastle disease virus results in increased fusion and decreased neuraminidase activities without changes in virus pathotype - (Peer Reviewed Journal)

Estevez, C., King, D.J., Lou, M., Yu, Q. 2011. A single amino acid substitution in the hemagglutinin-neuraminidase protein of Newcastle disease virus results in increased fusion and decreased neuraminidase activities without changes in virus pathotype. Journal of General Virology. 92:544-551.

Update on poultry viral diseases research conducted at Southeast Poultry Research Laboratory - (Abstract Only)

Pantin Jackwood, M.J., Swayne, D.E., Spackman, E., Suarez, D.L., Afonso, C.L., Miller, P.J., Zsak, L., Day, J.M., Yu, Q. 2011. Update on poultry viral diseases research conducted at Southeast Poultry Research Laboratory [abstract]. Proceedings of the United States Animal Health Association 114th Annual Meeting, November 17, 2010, Minneapolis, MN. p. 526-527.

Pathogenicity evaluation of different Newcastle disease virus chimeras in 4-week-old chickens - (Peer Reviewed Journal)

Susta, L., Miller, P.J., Afonso, C.L., Estevez, C., Yu, Q., Zhang, J., Brown, C.C. 2010. Pathogenicity evaluation of different Newcastle disease virus chimeras in 4-week-old chickens. Tropical Animal Health and Production. 42(8):1785-1795.

Passive antibody transfer in chickens to model maternal antibody after avian influenza vaccination - (Abstract Only) - (30-Dec-09)

Generation and biological assessment of recombinant avian metapneumovirus subgroup C (aMPV-C) viruses containing different length of the G gene. - (Peer Reviewed Journal)

Yu, Q., Estevez, C., Song, M., Kapczynski, D.R., Zsak, L. 2010. Generation and biological assessment of recombinant avian metapneumovirus subgroup C (aMPV-C) viruses containing different length of the G gene. Virus Research. 147:182-188.

Generation of recombinant avian metapneumovirus subgroup C (aMPV-C) viruses containing different length of the G gene. - (Proceedings)

Yu, Q., Estevez, C., Kapczynski, D.R., Zsak, L. 2009. Generation of recombinant avian metapneumovirus subgroup C (aMPV-C) viruses containing different length of the G gene. In: Proceedings of the 6th International Symposium on Avian Corona and Pneumoviruses and Complicating Pathogens, June 14-17, 2009, Rauischholzhausen, Germany. p. 315-325.

Biological assessment of recombinant avian metapneumovirus subgroup C (aMPV-C) viruses containing different length of the G gene in cultured cells and SPF turkeys. - (Abstract Only)

Yu, Q., Estevez, C., Kapczynski, D., Zsak, L. 2009. Biological assessment of recombinant avian metapneumovirus subgroup C (aMPV-C) viruses containing different length of the G gene in cultured cells and SPF turkeys (abstract). In: Proceedings of the 2009 Annual Meeting of American Association of Avian Pathologists, July 11-15, 2009, Seattle, Washington. p. 25.

Pathogenic assessment of recombinant avian metapneumovirus subgroup C viruses in SPF chickens and turkeys. - (Abstract Only)

Yu, Q., Estevez, C. N., King, D. J., Kapczynski, D. R., Zsak, L. 2008. Pathogenic assessment of recombinant avian metapneumovirus subgroup C viruses in SPF chickens and turkeys [abstract]. In: Abstracts of the 14th International Congress of Virology, Istanbul, Turkey. p. 318.

Generation of recombinant avian metapneumovirus subgroup C viruses for pathogenesis studies and vaccine development - (Abstract Only)

Yu, Q., Estevez, C. N., King, D. J., Kapczynski, D. R., Zsak, L. 2008. Generation of recombinant avian metapneumovirus subgroup C viruses for pathogenesis studies and vaccine development [abstract]. In: Proceedings of the 27th Annual Meeting of American Society for Virology, Cornell, New York. p. 296.

The role of antigenic composition of Newcastle disease (ND) vaccines in ND control - (Abstract Only)

Miller, P.J., Estevez, C., Yu, Q., Suarez, D.L., King, D.J. 2008. The role of antigenic composition of Newcastle disease (ND) vaccines in ND control [abstract]. In: Proceedings of the American Association of Avian Pathologists annual meeting, July 19-23, 2008, New Orleans, Louisiana. p. 65.

Glycoprotein gene truncation in avian metapneumovirus subtype C isolates from the United States - (Peer Reviewed Journal)

Velayudhan, B. T., Yu, Q., Nagaraja, K. V., Estevez, C. N., Halvorson, D. A. 2008. Glycoprotein gene truncation in avian metapneumovirus subtype C isolates from the United States. Virus Genes. 37(2):266-72.

Construction of a fowl adenovirus recombinant to express avian metapneumovirus glycoprotein - (Abstract Only)

Strother, K.O., Yu, Q., Kapczynski, D.R., Nagy, E., Zsak, L. 2008. Construction of a fowl adenovirus recombinant to express avian metapneumovirus glycoprotein [abstract]. American Association of Avian Pathologists Annual Convention, July 19-23, 2008, New Orleans, Louisiana. 2008 CDROM.

Research update on exotic and emerging poultry diseases - (Proceedings)

Pantin Jackwood, M.J., Suarez, D.L., Zsak, L., Spackman, E., Kapczynski, D.R., King, D.J., Afonso, C.L., Day, J.M., Spatz, S.J., Yu, Q., Swayne, D.E. 2007. Research update on exotic and emerging poultry diseases. In: Proceedings of the 111th Annual Meeting of the U. S. Animal Health Association, Reno, Nevada, October 22-23, 2007. p. 702-707. Available: http://www.usaha.org/meetings/2007/2007_USAHA_Proceedings.pdf.

Rescue of recombinant avian metapneumovirus subgroup C viruses from cloned DNAs for vaccine development and pathogenesis studies - (Proceedings)

Yu, Q., Estevez, C., King, D.J., Kapczynski, D.R., Zsak, L. 2007. Rescue of recombinant avian metapneumovirus subgroup C viruses from cloned DNAs for vaccine development and pathogenesis studies. In: Proceedings of 2007 Turkey Research Review and Avian Pneumovirus Symposium, September 26-27, 2007 Willmar, Minnesota. 2007 CDROM.

Evaluation of different hemagglutinin-neuraminidase and fusion protein chimeras using a reverse genetic system based on the mesogenic anhinga Newcastle disease virus strain - (Proceedings)

Estevez, C., King, D.J., Miller, P.J., Yu, Q. 2007. Evaluation of different hemagglutinin-neuraminidase and fusion protein chimeras using a reverse genetic system based on the mesogenic anhinga Newcastle disease virus strain. In: The 15th World Poultry Veterinarian Association Abstract Book, September 10-15, 2007, Beijing, China. p. 153.

Evaluation of Newcastle disease virus chimeras expressing the hemagglutinin-neuraminidase protein of velogenic strains in the context of a mesogenic recombinant virus backbone - (Peer Reviewed Journal)

Estevez, C., King, D.J., Seal, B.S., Yu, Q. 2007. Evaluation of Newcastle disease virus chimeras expressing the hemagglutinin-neuraminidase protein of velogenic strains in the context of a mesogenic recombinant virus backbone. Virus Research. 129:182-190.

A Newcastle disease virus hemagglutinin-neuraminidase mutation that diminished hemagglutination and neuraminidase activity did not change infectivity and pathogenecity - (Abstract Only)

Yu, Q., Estevez, C., King, D.J., Miller, P.J. 2007. A Newcastle disease virus hemagglutinin-neuraminidase mutation that diminished hemagglutination and neuraminidase activity did not change infectivity and pathogenecity [abstract]. In: Proceedings of the 26th Annual Meeting of American Society for Virology, July 14-18, 2007, Corvallis, Oregon. p. 106.

Evaluation of different hemagglutinin-neuraminidase (HN) chimeras using a newly developed reverse genetic system based on the mesogenic anhinga Newcastle disease virus strain - (Abstract Only)

Estevez, C., Yu, Q., King, D.J., Miller, P.J. 2007. Evaluation of different hemagglutinin-neuraminidase (HN) chimeras using a newly developed reverse genetic system based on the mesogenic anhinga Newcastle disease virus strain [abstract]. 144th American Veterinary Medical Association Annual Convention Notes, July 14-28, 2007, Washington, DC. CD, paper #4439.

Protection against exotic Newcastle disease virus (NDV) challenge of chickens vaccinated with NDV vaccines made from different genetic lineages - (Abstract Only)

Miller, P.J., Estevez, C., Yu, Q., Suarez, D.L., King, D.J. 2007. Protection against exotic Newcastle disease virus (NDV) challenge of chickens vaccinated with NDV vaccines made from different genetic lineages [abstract]. International Poultry Forum Proceedings. p. 31.

Characterization of monoclonal antibodies produced against Avian metapneumovirus Sybtype C - (Proceedings)

Yu, Q., Estevez, C., Kapczynski, D.R. 2006. Characterization of monoclonal antibodies produced against Avian metapneumovirus Sybtype C. Symposium on Avian Pneumovirus.

SEQUENCE ANALYSIS OF THE COMPLETE GENOME OF AVIAN METAPNEUMOVIRUS SUBGROUP C COLORADO STRAIN: DEVELOPMENT OF A REVERSE GENETICS SYSTEM FOR THIS VIRUS - (Peer Reviewed Journal)

Yu, Q., Estevez, C. 2006. Sequence analysis of the complete genome of avian metapneumovirus Subgroup C Colorado strain: development of a reverse genetics system for this virus. In: Proceedings of the International Symposium on Avian Corona and Pneumoviruses and Complicating Pathogens, May 14-16, 2006, Rauischholzhausen, Germany. p. 6-15.

Production and characterization of monoclonal antibodies that react to the nucleocapsid protein of avian metapneumovirus subtype C - (Peer Reviewed Journal)

Yu, Q., Estevez, C., Kapczynski, D.R. 2006. Production and characterization of monoclonal antibodies that react to the nucleocapsid protein of avian metapneumovirus subtype C. Avian Diseases. 50(3):419-424.

VIRAL RESCUE FROM AN INFECTIOUS CLONE OF A MESOGENIC NEWCASTLE DISEASE VIRUS - (Abstract Only)

Estevez, C., Seal, B.S., Yu, Q. 2006. Viral rescue from an infectious clone of a mesogenic Newcastle disease virus. In: Proceedings of the 14th Annual Meeting of American Society for Virology, July 15, 2006, Madison, WI. p.217.

DEVELOPMENT OF A GREEN FLUORESCENT PROTEIN (GFP)-BASED MINIREPLICON SYSTEM FOR NEWCASTLE DISEASE VIRUS - (Abstract Only)

Estevez, C., Yu, Q. 2006. Development of a green fluorescent protein (gfp)-based minireplicon system for newcastle disease virus [abstract]. Ninth Southeastern Regional Virology Conference Program Book. p. 15.

PRODUCTION AND CHARACTERIZATION OF MONOCLONAL ANTIBODIES PRODUCED AGAINST AVIAN METAPNEUMOVIRUS SUBTYPE C WHICH REACT AGAINST THE NUCLEOCAPSID PROTEIN - (Abstract Only)

Yu, Q., Estevez, C., Kapczynski, D.R. 2006. Production and characterization of monoclonal antibodies produced against Avian Metapneumovirus Subtype C which react against the nucleocapsid protein [abstract]. In: Proceedings of the 2006 Annual Meeting of American Association of Avian Pathologists, July 16-19, 2006, Honolulu, HI. p. 164.

A wild goose avian metapneumovirus containing a large attachment glycoprotein is avirulent but immunoprotective in domestic turkeys - (Peer Reviewed Journal)

Bennett, R.S., Larue, R., Shaw, D., Yu, Q., Halvorson, D.A., Njenga, M.K. 2005. A wild goose avian metapneumovirus containing a large attachment glycoprotein is avirulent but immunoprotective in domestic turkeys. Journal of Virology. 79(23):14834-14842.

SEQUENCE ANALYSIS OF THE COMPLETE GENOME OF AVIAN METAPNEUMOVIRUS SUBGROUP C COLORADO STRAIN: DEVELOPMENT OF A REVERSE GENETICS SYSTEM FOR THIS VIRUS - (Proceedings)

Yu, Q. 2005. Sequence analysis of the complete genome of avian metapneumovirus subgroup C Colorado strain: development of a reverse genetics system for this virus. In: Proceedings of 2005 Turkey Research Review and Avian Pneumovirus Symposium, October 5, 2005, Willmar, MN. 2005 CDROM.

GENOMIC SEQUENCES OF LOW VIRULENCE AVIAN PARAMYXOVIRUS 1 (NEWCASTLE DISEASE VIRUS) ISOLATES OBTAINED FROM LIVE-BIRD MARKETS IN NORTH AMERICA NOT RELATED TO COMMONLY UTILIZED COMMERCIAL VACCINE STRAINS - (Peer Reviewed Journal)

Seal, B.S., Wise, M., Pedersen, J.C., Senne, D.A., Alvarez, R., Scott, M.A., King, D.J., Yu, Q., Kapczynski, D.R. 2005. Genomic sequences of low virulence avian paramyxovirus 1 (Newcastle disease virus) isolates obtained from live-bird markets in North America not related to commonly utilized commercial vaccine strains. Veterinary Microbiology. 106(1-2):7-16.

COMPARISON OF THE FULL LENGTH GENOME SEQUENCE OF AVIAN METAPNEUMOVIRUS SUBTYPE C WITH OTHER PARAMYXOVIRUSES INCLUDING HIGHLY VIRULENT NEWCASTLE DISEASE VIRUSES - (Peer Reviewed Journal)

Lwamba, H.M., Alvarez, R., Wise, M., Yu, Q., Halvorson, D., Njenga, M., Seal, B.S.2005. Comparison of the Full Length Genome Sequence of Avian Metapneumovirus Subtype C With Other Paramyxoviruses Including Highly Virulent Newcastle Disease Viruses. Virus Research. 107(1):83-92.

CHARACTERIZATION OF RECOMBINANT RESPIRATORY SYNCYTIAL VIRUSES WITH THE ATTACHMENT (G) PROTEIN DELETED OF THE REGION RESPONSIBLE FOR TYPE 2 T CELL RESPONSES AND PULMONARY EOSINOPHILIA - (Peer Reviewed Journal)

Elliott, M.B., Pryharski, K.S., Yu, Q., Boutilier, L.A., Campeol, N., Melville, K., Laughlin, T.S., Gupta, C.K., Lerch, R.A., Randolph, V.B., Lapierre, N.A., Heers Dack, K.M., Hancock, G.E. 2004. Characterization of recombinant respiratory syncytial viruses with the attachment (G) protein deleted of the region responsible for type 2 T cell responses and pulmonary eosinophilia. Journal of Virology. 78:8446-8454.

RECOMBINANT RESPIRATORY SYNCYTIAL VIRUSES LACKING THE C-TERMINAL THIRD OF THE ATTACHMENT (G) PROTEIN ARE IMMUNOGENIC AND ATTENUATED IN VIVO AND IN VITRO - (Peer Reviewed Journal)

Elliott, M.B., Pryharski, K.S., Yu, Q., Parks, C.L., Laughlin, T.S., Gupta, K., Lerch, R.A., Randolph, V.B., Lapierre, N.A., Heers Dack, K.M., Hancock, G.E. 2004. Recombinant Respiratory Syncytial Viruses Lacking the C-Terminal Third of the Attachment (G) Protein Are Immunogenic and Attenuated In Vivo and In Vitro. Journal of Virology. 2004 Jun:78(11):5773-83.