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Agricultural Research Service United States Department of Agriculture
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Janice K Huwe
Animal Metabolism-Agricultural Chemicals Research
Research Chemist

Phone: (701) 239-1288
Fax: (701) 239-1430
1605 ALBRECHT BLVD
BRL
BIOSCIENCES RESEARCH LABORATORY
FARGO, ND, 58105-5674

Projects
Dioxins and Other Environmental Contaminants in Food
Appropriated (D)
  Accession Number: 410310

Publications
Levels and Trends of Historic POPs (PCDD/Fs and PCBs) and Newer POPs (PBDEs) in U.S. Meat and Poultry and Implications for Human Exposure - (Abstract) - (03-Nov-09)
A Survey of Polychlorinated Dibenzo-p-dioxins, Polychlorinated Dibenzofurans and Co-planar Polychlorinated Biphenyls in U.S. Meat and Poultry, 2007-2008 - (Peer Reviewed Journal)
Huwe, J.K., Pagan-Rodriguez, D., Abdelmajid, N., Clinch, N., Gordon, D., Holterman, J., Zaki, E., Lorentzsen, M.K., Dearfield, K. 2009. A Survey of Polychlorinated Dibenzo-p-dioxins, Polychlorinated Dibenzofurans and Co-planar Polychlorinated Biphenyls in U.S. Meat and Poultry, 2007-2008. Journal of Agriculture and Food Chemistry. DOI:10.1021/jf902251t.
Residue and Food Safety Research at the USDA ARS Animal Metabolism Research Unit - (Abstract)
Smith, D.J., Huwe, J.K., Hakk, H., Shappell, N.W., Shelver, W.L. 2009. Residue and Food Safety Research at the USDA ARS Animal Metabolism Research Unit. In: Proceedings of 4th International Symposium on Recent Advances in Food Analysis, November 4-6, 2009, Prague, Czech Republic. Poster A-54, page 33.
Fate and Metabolism of PBDEs in Mammalian Systems - (Abstract)
Huwe, J.K., Hakk, H. 2009. Fate and Metabolism of PBDEs in Mammalian Systems [Abstract]. International Society of Exposure Science 2009 Abstract Book, November 1-5, 2009, Minneapolis, MN. 2009-P-124-ISES, page 97.
Food Safety Research at USDA: Hormones in Water and POPs in Food - (Abstract)
Huwe, J.K., Shappell, N.W. 2009. Food Safety Research at USDA: Hormones in Water and POPs in Food. In: Proceedings of 4th International Symposium on Recent Advances in Food Analysis, November 4-6, 2009, Prague, Czech Republic. Presentation LS2, page 11.
Evaluation of Background Exposures of Americans to Dioxin-Like Compounds in the 1990's and the 2000's - (Peer Reviewed Journal)
Lorber, M., Patterson, D.G., Huwe, J.K., Kahn, H. 2009. Evaluation of Background Exposures of Americans to Dioxin-Like Compounds in the 1990's and the 2000's. Chemosphere. 77:640-651. DOI:10.1016/j.chemosphere.2009.08.016.
Concentrations of PCDD/PCDFs and PCBs in spent foundry sands - (Peer Reviewed Journal)
Dungan, R.S., Huwe, J.K., Chaney, R.L. 2009. Concentrations of PCDD/PCDFs and PCBs in spent foundry sands. Chemosphere. 75:1232-1235.
Absorption, Distribution, Metabolism and Excretion (ADME) Study with 2,2',4,4',5,6' Hexabromodiphenyl Ether(BDE 154)in Male Sprague-Dawley Rats - (Peer Reviewed Journal)
Hakk, H., Huwe, J.K., Larsen, G.L. 2009. Absorption, Distribution, Metabolism and Excretion (ADME) Study with 2,2',4,4',5,6' Hexabromodiphenyl Ether (BDE 154) in Male Sprague-Dawley Rats. Xenobiotica. 39:46-56.
Hypertension, Cardiac Hypertrophy, and Impaired Vascular Relaxation Induced by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin are Associated with Increased Superoxide - (Peer Reviewed Journal)
Kopf, P.G., Huwe, J.K., Walker, M.K. 2008. Hypertension, cardiac hypertrophy, and impaired vascular relaxation induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin are associated with increased superoxide. Cardiovascular Toxicology 8:181-193.
Tissue distribution of polybrominated diphenyl ethers in male rats and implications for biomonitoring - (Peer Reviewed Journal)
Huwe, J.K., Hakk, H., Birnbaum, L.S. 2008. Tissue distribution of polybrominated diphenyl ethers in male rats and implications for biomonitoring. Environmental Science and Technology 42:7018-7024. doi:10.1021/es801344a
Effect of updated 2005 TEFS on previous USDA food surveys of PCDD/Fs and co-planar PCBS and comparison to initial results from a new survey - (Peer Reviewed Journal)
Huwe, J.K., Dearfield, K., Pagan-Rodriguez, D., Clinch, N., Hicks, J., Holterman, J., Lorentzsen, M.K., Larsen, G.L., Gordon, D. 2008. Effect of updated 2005 TEFS on previous USDA food surveys of PCDD/Fs and co-planar PCBS and comparison to initial results from a new survey. Organohalogen Compounds 70:1514-1517.
Tissue distribution of polybrominated diphenyl ethers in rats following oral exposure and the relationship to body burdens - (Abstract)
Huwe, J.K., Hakk, H., Stapleton, H.M., Birnbaum, L.S. 2008. Tissue Distribution of Polybrominated Diphenyl Ethers in Rats Following Oral Exposure and the Relationship to Body Burdens [Abstract]. In: Abstract Book of the 18th Annual International Society of Exposure Analysis Conference, October 12-16, 2008, Pasadena, CA. Presentation S41-04, p 157.
Evaluation of automated direct sample introduction with comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry for the screening analysis of dioxins of fish oil - (Peer Reviewed Journal)
Hoh, E., Lehotay, S.J., Mastovska, K., Huwe, J.K. 2008. Evaluation of automated direct sample introduction with comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry for the screening analysis of dioxins of fish oil. Journal of Chromatography A. 1201(1):69-77.
Comparative absorption and bioaccumulation of polybrominated diphenyl ethers following ingestion via dust and oil in male rats - (Peer Reviewed Journal)
Huwe, J.K., Hakk, H., Smith, D.J., Diliberto, J.J., Richardson, V., Birnbaum, L.S., Stapleton, H.M. 2008. Comparative absorption and bioaccumulation of polybrominated diphenyl ethers following ingestion via dust and oil in male rats. Environmental Science and Technology 42:2694-2700.
In utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: Effects on fetal and adult cardiac gene expression and adult cardiac and renal morphology - (Peer Reviewed Journal)
Aragon, A.C., Kopf, P.G., Campen, M.J., Huwe, J.K., Walker, M.K. 2008. In utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: Effects on fetal and adult cardiac gene expression and adult cardiac and renal morphology. Toxicological Sciences 101(2):321-330.
Are polybrominated diphenyl ethers from household dust bioavailable and biologically active? - (Abstract)
Huwe, J.K., Hakk, H., Stapleton, H., Diliberto, J., Richarson, V., Birnbaum, L. 2007. Are polybrominated diphenyl ethers from household dust bioavailable and biologically active?. Meeting Abstract. International Society of Exposure Analysis, Oct. 14-18, 2007, Durham, NC.
Brominated flame retardants as food contaminants - (Book/Chapter)
Covaci, A., Voorspoels, S., D'Silva, K., Huwe, J.K., Harrad, S. 2008. Brominated flame retardants as food contaminants IN Wilson & Wilson's Comprehensive Analytical Chemistry, Food Contaminants and Residue Analysis, Vol 51:507-570.
Accumulation, Whole-body Depletion, and Debromination of Decabromodiphenyl Ether (BDE-209) in Male Sprague-Dawley Rats Following Dietary Exposure - (Peer Reviewed Journal)
Huwe, J.K., Smith, D.J. 2007. Accumulation, Whole-body Depletion, and Debromination of Decabromodiphenyl Ether (BDE-209) in Male Sprague-Dawley Rats Following Dietary Exposure. Environmental Science and Technology 41:2371-2377.
Comparative oral bioavailability of PBDEs from dust and oil in male rats. - (Abstract)
Huwe, J.K., Hakk, H., Diliberto, J.J., Staplet0n, H., Birnbaum, L.S. 2007. Comparative oral bioavailability of PBDEs from dust and oil in male rats. BFR 2000, 4th International Workshop on Brominated Flame Retardants. 04/24-27/2007, Amsterdam, Netherlands.
An ADME study with 2,2'4,4',-tetrabromodiphenyl ether (BDE-47) in chickens. - (Abstract)
Hakk, H., Huwe, J.K., Larsen, G.L. 2007. An ADME study with 2,2'4,4',-tetrabromodiphenyl ether (BDE-47) in chickens. Meeting Abstract. BFR 2007 4th International Workshop on Brominated Flame Retardants, April 24-27, 2007, Amsterdam, The Netherlands.
Bioavailability of PBDEs in male rats from orally administered household dust - (Abstract)
Hakk, H., Huwe, J.K., Diliberto, J.J., Stapleton, H., Birnbaum, L.S. 2007. Bioavailability of PBDEs in male rats from orally administered household dust. Meeting Abstract. 46th Annual Meeting of the Society of Toxicology, March 25-29, 2007, Charlotte, NC.
Effect of Sodium [36cl]chlorate Dose on Total Radioactive Residues and Residues of Parent Chlorate in Growing Swine - (Peer Reviewed Journal)
Smith, D.J., Anderson, R.C., Huwe, J.K. Effect of sodium [36cl]chlorate dose on total radioactive residues and residues of parent chlorate in growing swine. Journal of Agriculture and Food Chemistry 54:8648-8653.
Pcdd and Pcdf Emissions from Simulated Sugarcane Field Burning - (Peer Reviewed Journal)
Gullett, B.K., Touati, A., Huwe, J.K., Hakk, H. 2006. PCDD and PCDF emissions from simulated sugarcane field burning. Environmental Science and Technology. 40(20):6228-6234.
A Statistically-Designed Survey of Polychlorinated Dibenzo-P-Dioxins, Polychlorinated Dibenzofurans and Co-Planar Polychlorinated Biphenyls in U.S. Meat and Poultry, 2002-2003: Results, Trends, and Implications - (Peer Reviewed Journal)
Hoffman, M.K., Huwe, J.K., Deyrup, C.L., Lorentzsen, M.K., Zaylskie, R.G., Clinch, N.R., Saunders, P., Sutton, W.R. 2006. Statistically-Designed Survey of Polychlorinated Dibenzo-p-Dioxins, Polychlorinated Dibenzofurans and Co-Planar Polychlorinated Biphenyls in U.S. Meat and Poultry, 2002-2003: Results, Trends, and Implications. Environmental Science and Technology. 40:5340-5346
Uptake of Dioxin-Like Compounds in Growing Swine: Correlation Between Experimental and Predicted Data - (Peer Reviewed Journal)
Huwe, J.K. Uptake of dioxin-like compounds in growing swine: correlation between experimental and predicted data. Organohalogen Compounds 68.
Bioavailability and Mass Balance Studies of a Commercial Pentabromodiphenyl Ether Mixture in Male Sprague-Dawley Rats - (Peer Reviewed Journal)
Huwe, J.K., Hakk, H., Lorentzsen, M.K. 2007. Bioavailability and mass balance studies of a commercial pentabromodiphenyl ether mixture in male Sprague-Dawley rats. Chemosphere 66:259-266.
Effects of Short-Chain Nitrocompounds Against Campylobacter Jejuni and Campylobacter Coli in Vitro - (Peer Reviewed Journal)
Horrocks, S.M., Jung, Y., Huwe, J.K., Harvey, R.B., Ricke, S.C., Carstens, G.E., Callaway, T.R., Anderson, R.C., Ramlachan, N., Nisbet, D.J. 2007. Effects of short-chain nitrocompounds against Campylobacter jejuni and Campylobacter coli in vitro. Journal of Food Science. 72:M50-M55.
Tissue Disposition, Excretion, and Metabolism of 2,2',4,4',6-Pentabromodiphenyl Ether (Bde-100) in Male Sprague-Dawley Rats. - (Peer Reviewed Journal)
Hakk, H., Huwe, J.K., Low, M.C., Rutherford, D., Larsen, G.L. 2006. Tissue disposition, excretion, and metabolism of 2,2',4,4',6-pentabromodiphenyl ether (BDE-100) in male Sprague-Dawley rats. Xenobiotica 36(1):79-94.
Modern Analytical Methods for Chemical Residue Detection - (Proceedings/Symposium)
Huwe, J.K. 2005. Modern analytical methods for chemical residue detection. Proceedings of MOST-USDA Workshop on Agricultural Products Processing and Food Safety, Sept. 21-24, 2005, Beijing, China, p. 391.
Dioxins and Dioxin-Like Compounds in Domestic Meats. - (Proceedings/Symposium)
Huwe, J.K., Larsen, G.L. 2005. Dioxins and dioxin-like compounds in domestic meats. Proceedings of the 6th International Symposium on the Epidemiology & Control of Foodborne Pathogens in Pork (SafePork 2005), Sept. 6-9, 2005, Rohnert Park, CA, pp. 129-132.
Bioaccumulation of Decabromodiphenyl Ether (Bde-209) from the Diet into Sprague-Dawley Rats. - (Peer Reviewed Journal)
Huwe, J.K. 2005. Bioaccumulation of decabromodiphenyl ether (BDE-209) from the diet into Sprague-Dawley rats. Organohalogen Compounds 67:633-635.
An Adme Study with 2,2',4,4',5,6'-Hexabromodiphenyl Ether (Bde-154) in Male Spragye-Dawley Rats. - (Peer Reviewed Journal)
Hakk, H., Huwe, J.K., Larsen, G.L. 2005. An ADME study with 2,2',4,4',5,6'-hexabromodiphenyl ether (BDE-154) in male Sprague-Dawley rats. Organohalogen Compounds 67:2339-2342.
Polychlorinated Dioxins, Furans, and Biphenyls, and Polybrominated Diphenyl Ethers in a Us Meat Market Basket and Estimates of Dietary Intake - (Peer Reviewed Journal)
Huwe, J.K., Larsen, G.L. 2005. Polychlorinated dioxins, furans, and biphenyls, and polybrominated diphenyl ethers in a U.S. meat market basket and estimates of dietary intake. Environmental Science and Technology 39(15):5606-5611.
Laboratory and on-Farm Studies on the Bioavailability of Dioxins from a Contaminated Mineral Supplement Fed to Dairy Cows - (Peer Reviewed Journal)
Huwe, J.K., Smith, D.J. 2005. Laboratory and on-farm studies on the bioavailability of dioxins from a contaminated mineral supplement fed to dairy cows. Journal of Agriculture and Food Chemistry 53:2362-2370.
A Survey of Pcdd/fs and Co-Planar Pcbs in the Us Meat and Poultry Supply in 2002-2003 - (Peer Reviewed Journal)
Huwe, J.K., Hoffman, M.K., Deyrup, C., Hulebak, K., Larsen, G.L., Zaylskie, R., Lorentzsen, M.K., Clinch, N. 2004. A survey of pcdd/fs and co-planar pcbs in the us meat and poultry supply in 2002-2003. Organohalogen Compounds 66:1942-1946.
Binding of 2,2',4,4',6-Pentabromodiphenyl Ether (Bde-100) And/or Its Metabolites to Mammalian Biliary Carrier Proteins - (Peer Reviewed Journal)
Larsen, G.L., Huwe, J.K., Low, M., Rutherford, D., Hakk, H. 2004. Binding of 2,2',4,4',6-pentabromodiphenyl ether (bde-100) and/or its metabolites to mammalian biliary carrier proteins. Organohalogen Compounds 66:3830-3835.
Biotransformation of [14c]-Phenylbutazone after Oral Or Intravenous Administration to Cattle - (Abstract)
Smith, D.J., Huwe, J.K., Lorentzsen, M.K., Harrington, G.E. 2004. Biotransformation of [14c]-phenylbutazone after oral or intravenous administration to cattle. [abstract] American Chemical Society National Meeting, Philadelphia, PA, 8/22-26/2004, Picogram No. 67, Abstract No. 124.
Polybrominated Diphenyl Ethers in Meat Samples Collected from Supermarkets Across the Us - (Proceedings/Symposium)
Huwe, J.K. 2004. Polybrominated diphenyl ethers in meat samples collected from supermarkets across the US. [abstract] Abstracts of the 3rd International Workshop on Brominated Flame Retardants, June 6-9, 2004, Toronto, ON, Canada. pp. 41-44.
Levels of Polychlorinated Dibenzo-P-Dioxins and Dibenzofurans in Cattle Raised at Agricultural Research Facilities Across the Usa and the Influence of Pentachlorophenol-Treated Wood. - (Peer Reviewed Journal)
Huwe, J.K., Davison, K., Feil, V.J., Larsen, G.L., Lorentzsen, M.K., Zaylskie, R., Tiernan, T.O. 2004. Levels of polychlorinated dibenzo-p-dioxins and dibenzofurans in cattle raised at agricultural research facilities across the USA and the influence of pentachlorophenol-treated wood. Journal of Food Additives & Contaminants 21(2):182-194.
Transfer and Bioconcentration of Dioxins from Feeds into Beef Cattle and Dairy Cows. - (Other)
Huwe, Janice K. Transfer and Bioconcentration of Dioxins from Feeds into Beef Cattle and Dairy Cows. www.feedinfo.com
Uptake and Excretion of Pcdd/fs from a Magnesium Mineral Supplement Fed to Dairy Cows. - (Peer Reviewed Journal)
Huwe, J.K., Smith, D.J. 2003. Uptake and excretion of pcdd/fs from a magnesium mineral supplement fed to dairy cows. Organohalogen Compounds. 64:419-422.
Calux and High Resolution Gc/ms Analysis of Dioxin-Like Compounds in Chlorophenoxy Pesticide Formulations. - (Peer Reviewed Journal)
Huwe, J.K., Clark, G., Chu, A., Garry, V. 2003. Calux and high resolution gc/ms analysis of dioxin-like compounds in chlorophenoxy pesticide formulations. Organohalogen Compounds. 60:227-230.
A Mass Balance Feeding Study of a Commercial Octabromodiphenyl Ether Mixture in Rats - (Peer Reviewed Journal)
Huwe, J.K., Hakk, H., Lorentzsen, M.K. 2002. A mass balance feeding study of a commercial octabromodiphenyl ether mixture in rats. Organohalogen Compounds. 58:229-232.
Comparison of Soxhlet and Accelerated Solvent Extractions in the Analysis of Dioxins and Furans from Liver Samples - (Peer Reviewed Journal)
Huwe, J.K. 2002. Comparison of soxhlet and accelerated solvent extractions in the analysis of dioxins and furans from liver samples. Organohalogen Compounds. 58:229-232.

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