Building on previous studies using site-directed mutagenesis
Relationship of viroid sequence/structure to function
Viroid/host interactions - protein kinase signaling in viroid pathogenesis
Identification of nuclear targeting signals on viroid molecules
Characterization of plant viral genomes and genome expression
Development of novel plant viral-based vectors
Contribute knowledge towards controlling viral diseases
Development and utilization of plant viral-based vectors for transient gene expression of candidate sequences/ proteins for plant and animal disease control
Cucumber mosaic virus - Virus-like particles expressing engineered Newcastle Disease Virus (NDV) epitope and decorated with antiserum to NDV (L. Nemchinov and W. D. Swaim and R. W. Hammond)