Projects

Development of Strategies to Control Anaplasmosis Appropriated (D)   Accession Number: 422174

Pharmacological and Immunologic Interventions Against Vector-Borne Bovine and Equine Babesiosis Appropriated (D)   Accession Number: 422175

THREAT OF CATTLE FEVER IN TEXAS: SCREENING FOR THE PRESENCE OF BABESIA AND DETERMINING TICK POPULATION STRUCTURE USING MOLECULAR GENETICS Reimbursable (R)   Accession Number: 419642

TICK-HOST-LANDSCAPE INTERACTIONS INFLUENCING THE ECOLOGY OF EQUINE PIROPLASMOSIS IN SUB-TROPICAL TEXAS Specific Cooperative Agreement (S)   Accession Number: 422543

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Subdominant antigens in bacterial vaccines: Am779 is subdominant in the anaplasma marginale outer membrane vaccine but does not associate with protective immunity - (Peer Reviewed Journal)

Albarrak, S.M., Brown, W.C., Noh, S.M., Reif, K.E., Scoles, G.A., Turse, J.E., Norimine, J., Ueti, M.W., Palmer, G.H. 2012. Subdominant antigens in bacterial vaccines: Am779 is subdominant in the anaplasma marginale outer membrane vaccine but does not associate with protective immunity. PLoS One. PloSONE 7(9):e46372.

Analysis of Babesia bovis-induced gene expression changes in the cattle tick, Rhipicephalus (Boophilus) microplus - (Peer Reviewed Journal)

Heekin, A.M., Guerrero, F., Bendele, K.G., Saldivar, L., Scoles, G.A., Gondro, C., Nene, V., Djikeng, A., Brayton, K.A. 2012. Analysis of Babesia bovis-induced gene expression changes in the cattle tick, Rhipicephalus (Boophilus) microplus. Parasites & Vectors. 5:162.

Expansion of variant diversity associated with high prevalence of pathogen strain superinfection under conditions of natural transmission - (Peer Reviewed Journal)

Ueti, M.W., Tan, Y., Broschat, S., Castaneda-Ortiz, E., Camacho-Nuez, M., Mosqueda, J., Scoles, G.A., Grimes, M., Brayton, K., Palmer, G. 2012. Expansion of variant diversity associated with high prevalence of pathogen strain superinfection under conditions of natural transmission. Infection and Immunity. 80(7):2354-60.

Identification of endosymbionts in ticks by broad-range polymerase chain reaction and electrospray ionization mass spectrometry - (Peer Reviewed Journal)

Rounds, M.A., Crowder, C.D., Matthews, H.E., Philipson, C.A., Scoles, G.A., Eshoo, M.W. 2012. Identification of endosymbionts in ticks by broad-range polymerase chain reaction and electrospray ionization mass spectrometry. Applied and Environmental Microbiology. 49(4):843-850.

Analysis of Babesia bovis-induced gene expression changes in the cattle tick, Rhipcephalus (Boophilus) microplus. - (Other) - (30-Jan-12)

Dispersion and sampling of adult dermacentor andersoni in rangeland in Western North America - (Peer Reviewed Journal)

Rochon, K., Scoles, G.A., Lysyk, T.J. 2012. Dispersion and sampling of adult dermacentor andersoni in rangeland in Western North America. Journal of Economic Entomology. 49:253-261.

Dermacentor andersoni transmission of Francisella tularensis subsp. novicida reflects bacterial colonization, dissemination and replication coordinated with tick feeding. - (Peer Reviewed Journal)

Reif, K., Palmer, G.H., Ueti, M.W., Scoles, G.A., Noh, S.M. 2011. Dermacentor andersoni transmission of Francisella tularensis subsp. novicida reflects bacterial colonization, dissemination and replication coordinated with tick feeding.. Infection and Immunity. 79(12):4941-6.

Equine Piroplasmosis Associated with Amblyomma cajennense Ticks, Texas, USA - (Peer Reviewed Journal)

Scoles, G.A., Hutcheson, H.J., Schlater, J.L., Hennager, S.G., Pelzel, A.M., Knowles Jr, D.P. 2011. Equine Piroplasmosis Associated with Amblyomma cajennense Ticks, Texas, USA. Emerging Infectious Diseases. 17(10)1903-1905.

Assessment of bacterial diversity in the cattle tick Rhipicephalus (Boophilus) microplus through tag-encoded pyrosequencing - (Peer Reviewed Journal)

Andreotti, R., Perez De Leon, A.A., Dowd, S.E., Guerrero, F., Bendele, K.G., Scoles, G.A. 2011. Assessment of bacterial diversity in the cattle tick Rhipicephalus (Boophilus) microplus through tag-encoded pyrosequencing. BMC Microbiology. 11:article 6.

The Rhipicephalus (Boophilus) microplus Bm86 gene plays a critical role in the fitness of ticks fed on cattle during acute Babesia bovis infection - (Peer Reviewed Journal)

Bastos, R., Ueti, M.W., Knowles Jr, D.P., Scoles, G.A. 2010. The Rhipicephalus (Boophilus) microplus Bm86 gene plays a critical role in the fitness of ticks fed on cattle during acute Babesia bovis infection. Parasites & Vectors. 3:111.

Anaplasma marginale infection with persistent high-load bacteremia induces a dysfunctional memory CD4+ T lymphocyte response but sustained high IgG titers - (Peer Reviewed Journal)

Han, S., Norimine, J., Brayton, K.A., Palmer, G.H., Scoles, G.A., Brown, W.C. 2011. Anaplasma marginale infection with persistent high-load bacteremia induces a dysfunctional memory CD4+ T lymphocyte response but sustained high IgG titers. Clinical and Vaccine Immunology. 17(12): 1881-1890. (doi:10.1128/CVI.00257-10).

Assessment of bacterial diversity in the cattle tick Rhipicephalus microplus through tag-encoded pyrosequencing - (Proceedings)

Andreotti, R., Perez De Leon, A.A., Dowd, S.E., Guerrero, F., Bendele, K.G., Scoles, G.A. 2011. Assessment of bacterial diversity in the cattle tick Rhipicephalus microplus through tag-encoded pyrosequencing. Acarology International Congress Proceedings. 6:11.

Detection of Babesia DNA in cattle fever ticks using a Reverse Line BLot - (Proceedings) - (10-Jun-10)

One Health Approach to Identify Research Needs in Bovine and Human Babesioses: Workshop Report - (Peer Reviewed Journal)

Perez De Leon, A.A., Strickman, D.A., Knowles Jr, D.P., Fish, D., Thacker, E.L., De La Fuente, J., Krause, P.J., Wikel, S.K., Miller, R., Wagner, G.G., Almazan, C., Hillman, R., Messenger, M.T., Ugstad, P.O., Duhaime, R.A., Teel, P.D., Ortega-Santos, A., Hewitt, D.G., Bowers, E.J., Bent, S.J., Cochran, M.H., Mcelwain, T.F., Scoles, G.A., Suarez, C.E., Davey, R.B., Freeman, J.M., Lohmeyer, K.H., Li, A.Y., Guerrero, F., Kammlah, D.M., Phillips, P.L., Pound, J.M. 2010. One Health approach to identify research needs in bovine and human babesioses: Workshop report. Parasites & Vectors. 3:Article 36.

Silencing of a putative immunophilin gene in the cattle tick Rhipicephalus (Boophilus) microplus increases the infection rate of Babesia bovis in larval progeny - (Peer Reviewed Journal)

Bastos, R., Ueti, M.W., Guerrero, F., Knowles Jr, D.P., Scoles, G.A. 2009. Silencing of a putative immunophilin gene in the cattle tick Rhipicephalus (Boophilus) microplus increases the infection rate of Babesia bovis in larval progeny. BioMed Central (BMC) Vectors and Parasites. 2(1):57.

Silencing of a putative immunophilin gene in the cattle tick Rhipicephalus (Boophilus) microplus increases the infection rate of Babesia bovis in larval progeny - (Peer Reviewed Journal)

Bastos, R.G., Ueti, M.W., Guerrero, F., Knowles Jr, D.P., Scoles, G.A. 2009. Silencing of a putative immunophilin gene in the cattle tick Rhipicephalus (Boophilus) microplus increases the infection rate of Babesia bovis in larval progeny. Parasites & Vectors. 2:article 57.

Imidocarb dipropionate clears persistent Babesia caballi infection with elimination of transmission potential - (Peer Reviewed Journal)

Schwint, O.N., Ueti, M.W., Palmer, G.H., Kappmeyer, L.S., Hines, M.T., Cordes, R.T., Knowles Jr, D.P., Scoles, G.A. 2009. Imidocarb dipropionate clears persistent Babesia caballi infection with elimination of transmission potential. Antimicrobial Agents and Chemotherapy. 53(10):4327-4332.

Quantification of Theileria parva in Rhipicephalus appendiculatus (Acari: Ixodidae) Confirms Differences in Infection Between Selected Tick Strains - (Peer Reviewed Journal)

Odongo, D., Ueti, M.W., Mwaura, S., Knowles Jr, D.P., Bishop, R., Scoles, G.A. 2009. Quantification of Theileria parva in Rhipicephalus appendiculatus (Acari: Ixodidae) Confirms Differences in Infection Between Selected Tick Strains. Journal of Medical Entomology. 46(4):888-894.

Transovarial Transmission of Francisella-Like Endosymbionts and Anaplasma phagocytophilum Variants in Dermacentor albipictus (Acari: Ixodidae) - (Peer Reviewed Journal)

Baldridge, G.D., Scoles, G.A., Burkhardt, N.Y., Schloeder, B., Kurtti, T.J., Munderloh, U.G. 2009. Transovarial Transmission of Francisella-Like Endosymbionts and Anaplasma phagocytophilum Variants in Dermacentor albipictus (Acari: Ixodidae). Journal of Medical Entomology. 46(3):625-632.

Quantitative Differences in Salivary Pathogen Load during Tick Transmission Underlie Strain-Specific Variation in Transmission Efficiency of Anaplasma marginale - (Peer Reviewed Journal)

Ueti, M.W., Knowles Jr, D.P., Davitt, C.M., Scoles, G.A., Baszler, T.V., Palmer, G.H. 2009. Quantitative Differences in Salivary Pathogen Load during Tick Transmission Underlie Strain-Specific Variation in Transmission Efficiency of Anaplasma marginale. Infection and Immunity. 77(1):70-75.

Microarray analysis of Rhipicephalus (Boophilus) microplus gene expression associated with Babesia bovis infection - (Proceedings)

Guerrero, F., Scoles, G.A., Saldivar, L., Brayton, K.A. 2008. Microarray analysis of Rhipicephalus (Boophilus) microplus gene expression associated with Babesia bovis infection. In Proceedings of the VI Internacional Seminar of Animal Parasitology, September 3-5, 2008, Vera Cruz, Mexico. 2008 CDROM.

Reproductive Compatibility of Prairie and Montane Populations of Dermacentor andersoni - (Peer Reviewed Journal)

Lysyk, T.J., Scoles, G.A. 2008. Reproductive Compatibility of Prairie and Montane Populations of Dermacentor andersoni. Journal of Medical Entomology. 45(6):1064-1070.

Expressed gene sequences from larval genes over-expressed upon Babesia bovis infection of Rhipecephalus (Boophilus) microplus - (Other)

Saldivar, L., Guerrero, F., Nene, V.M., Scoles, G.A. 2009. Expressed gene sequences from larval genes over-expressed upon Babesia bovis infection of Rhipecephalus (Boophilus) microplus. National Center for Biotechnology Information (NCBI). Available: http://ncbi.nlm.nih.gov. Assession numbers FG579553-FG579858.

Expressed gene sequences from adult ovary and adult female gut genes over-expressed upon Babesia bovis infection of Rhipcephalus (Boophilus) microplus - (Other)

Saldivar, L., Guerrero, F.D., Nene, V.M., Bendele, K.G., Scoles, G.A. 2009. Expressed gene sequences from adult ovary and adult female gut genes over-expressed upon Babesia bovis infection of Rhipcephalus (Boophilus) microplus. National Center for Biotechnology Information (NCBI). Available: http://www.ncbi.nhm.nih.gov. Accession numbers FG305399-FG309475 (Gut)and FG301341-FG305398 (Ovary).

Persistently Infected Horses Are Reservoirs for Intrastadial Tick-Borne Transmission of the Apicomplexan Parasite Babesia equi - (Peer Reviewed Journal)

Ueti, M.W., Palmer, G.H., Scoles, G.A., Kappmeyer, L.S., Knowles Jr, D.P. 2008. Persistently Infected Horses Are Reservoirs for Intrastadial Tick-Borne Transmission of the Apicomplexan Parasite Babesia equi. Infection and Immunity. 76(8):3525-3529.

Microarray analysis of expressed genes from Rhipcephalus (Boophilus) microplus larvae, adult ovary, and adult female gut associated with Babesia bovis infection - (Other)

Saldivar, L., Guerrero, F., Bendele, K.G., Brayton, K.A., Scoles, G.A. 2008. Microarray analysis of expressed genes from Rhipcephalus (Boophilus) microplus larvae, adult ovary, and adult female gut associated with Babesia bovis infection. National Center for Biotechnology Information (NCBI). Available: http://www.ncbi.nlm.nih.gov. GEO Submissions Series Record Number GSE10816, Sample Numbers GSM273028-273051.

A novel SINE family occurs frequently in both genomic DNA and transcribed sequences in ixodid ticks of the arthropod sub-phylum Chelicerata. - (Peer Reviewed Journal)

Sunter, J.D., Patel, S.P., Skilton, R.A., Githaka, N., Knowles Jr, D.P., Scoles, G.A., Nene, V., De Villiers, E., Bishop, R. 2008. A novel SINE family occurs frequently in both genomic DNA and transcribed sequences in ixodid ticks of the arthropod sub-phylum Chelicerata. Gene. 415(1-2):13-22.

Transmission of Babesia caballi by Dermacentor nitens (Acari: Ixodidae) Is Restricted to One Generation in the Absense of Alimentary Reinfection on a Susceptible Equine Host - (Peer Reviewed Journal)

Schwint, N.O., Knowles Jr, D.P., Ueti, M.W., Kappmeyer, L.S., Scoles, G.A. 2008. Transmission of Babesia caballi by Dermacentor nitens (Acari: Ixodidae) Is Restricted to One Generation in the Absense of Alimentary Reinfection on a Susceptible Equine Host. Journal of Medical Entomology. 45(6):1152-1155.

Validation of an Anaplasma marginale cELISA for use in the diagnosis of A. ovis infections in domestic sheep and Anaplasma spp. in wild ungulates - (Peer Reviewed Journal)

Scoles, G.A., Goff, W.L., Lysyk, T.J., Lewis, G.S., Knowles Jr, D.P. 2008. Validation of an Anaplasma marginale cELISA for use in the diagnosis of A. ovis infections in domestic sheep and Anaplasma spp. in wild ungulates. Veterinary Microbiology. 130:184-190.

Proteomic profiling of Rhipicephalus (Boophilus) microplus midgut responses to infection with Babesia bovis - (Peer Reviewed Journal)

Rachinsky, A.S., Guerrero, F., Scoles, G.A. 2008. Proteomic profiling of Rhipicephalus (Boophilus) microplus midgut responses to infection with Babesia bovis. Veterinary Parasitology. 152(3-4):294-313.

Serial analysis of gene expression associated with Babesoa bovis infection of Rhipecephalus (Boophilus) microplus - (Other)

Guerrero, F., Saldivar, L., Bendele, K.G., Scoles, G.A. 2008. Serial analysis of gene expression associated with Babesoa bovis infection of Rhipecephalus (Boophilus) microplus. National Center for Biotechnology Information (NCBI). Available: http://www.ncbi.nlm.nih.gov. GEO Submissions Series Record Number GSE9880.

Differential protein expression in ovaries of uninfected and Babesia-infected southern cattle ticks, Rhipicephalus (Boophilus) microplus - (Peer Reviewed Journal)

Rachinsky, A., Guerrero, F.D., Scoles, G.A. 2007. Differential protein expression in ovaries of uninfected and Babesia-infected southern cattle ticks, Rhipicephalus (Boophilus) microplus. Insect Biochemistry and Molecular Biology. 37:1291-1308.

Persistently Infected Calves as Reservoirs for Acquisition and Transovarial Transmission of Babesia bovis by Rhipicephalus (Boophilus) microplus - (Peer Reviewed Journal)

Howell, J.M., Ueti, M.W., Palmer, G.H., Scoles, G.A., Knowles Jr, D.P. 2007. Persistently Infected Calves as Reservoirs for Acquisition and Transovarial Transmission of Babesia bovis by Rhipicephalus (Boophilus) microplus. Journal of Clinical Microbiology. 45(10):3155-3159

Comparison of the Efficiency of Biological Transmission of Anaplasma marginale (Rickettsiales: Anaplasmataceae) by Dermacentor andersoni Stiles (Acari: Ixodidae) with Mechanical Transmission by the Horse Fly, Tabanus fuscicos - (Peer Reviewed Journal)

Scoles, G.A., Miller, J.A., Foil, L.D. 2008. Comparison of the Efficiency of Biological Transmission of Anaplasma marginale (Rickettsiales: Anaplasmataceae) by Dermacentor andersoni Stiles (Acari: Ixodidae) with Mechanical Transmission by the Horse Fly, Tabanus fuscicostatus Hine (Diptera: Muscidae). Journal of Medical Entomology. 45(1):109-114.

Identification of Midgut and Salivary Glands as Specific and Distinct Barriers to Efficient Tick-Borne Transmission of Anaplasma marginale - (Peer Reviewed Journal)

Ueti, M.W., Reagon, J.O., Knowles Jr, D.P., Scoles, G.A., Shkap, V., Palmer, G.H. 2007. Identification of Midgut and Salivary Glands as Specific and Distinct Barriers to Efficient Tick-Borne Transmission of Anaplasma marginale. Infection and Immunity. 75(6):2959-2964

Transovarial Transmission Efficiency of Babesia bovis Tick Stages Acquired by Rhipicephalus (Boophilus) microplus during Acute Infection - (Peer Reviewed Journal)

Howell, J.M., Ueti, M.W., Palmer, G.H., Scoles, G.A., Knowles Jr, D.P. 2007. Transovarial Transmission Efficiency of Babesia bovis Tick Stages Acquired by Rhipicephalus (Boophilus) microplus during Acute Infection. Journal of Clinical Microbiology. 45(2):426-431.

Conservation of Transmission Phenotype of Anaplasma marginale (Rickettsiales: Anaplasmataceae) Strains Among Dermacentor and Rhipicephalus Ticks (Acari: Ixodidae) - (Peer Reviewed Journal)

Scoles, G.A., Ueti, M.W., Noh, S.M., Knowles Jr, D.P., Palmer, G.H. 2007. Conservation of Transmission Phenotype of Anaplasma marginale (Rickettsiales: Anaplasmataceae) Strains Among Dermacentor and Rhipicephalus Ticks (Acari: Ixodidae). Journal of Medical Entomology. 44(3):484-491

A Canadian Bison Isolate of Anaplasma marginale (Rickettsialles: Anaplasmataceae) Is Not Transmissible by Dermacentor andersoni (Acari: Ixodidae), Whereas Ticks from Two Canadian D. andersoni Populations Are Competent Vectors - (Peer Reviewed Journal)

Scoles, G.A., Mcelwain, T.F., Rurangirwa, F.R., Knowles Jr, D.P., Lysyk, T.J. 2006. A Canadian Bison Isolate of Anaplasma marginale (Rickettsiales: Anaplasmataceae) Is Not Transmissible by Dermacentor andersoni (Acari: Ixodidae), Whereas Ticks from Two Canadian D. andersoni Populations Are Competent Vectors of a U.S. Strain. Journal of Medical Entomology. 43(5): 971-975.

ABILITY OF THE VECTOR TICK BOOPHILUS MICROPLUS TO ACQUIRE AND TRANSMIT BABESIA EQUI FOLLOWING FEEDING ON CHRONICALLY INFECTED HORSES WITH LOW LEVEL PARASITEMIA - (Peer Reviewed Journal)

Ueti, M.W., Palmer, G.H., Kappmeyer, L.S., Statdfield, M., Scoles, G.A., Knowles Jr, D.P. 2005. Ability of the Vector Tick Boophilus microplus To Acquire and Transmit Babesia equi following Feeding on Chronically Infected Horses with Low-Level Parasitemia. Journal of Clinical Microbiology. 43(8):3755-3759.

RELATIVE EFFICIENCY OF BIOLOGICAL TRANSMISSION OF ANAPLASMA MARGINALE (RICKETTSIALES: ANAPLASMATACEAE) BY DERMACENTOR ANDERSONI STILES (ACARI: IXODIDAE) COMPARED TO MECHANICAL TRANSMISSION BY STOMOXYS CALCITRANS (L.)(DIPTERA: - (Peer Reviewed Journal)

Scoles, G.A., Lysyk, T.J., Broce, A.B., Palmer, G.H. 2005. Relative Efficiency of Biological transmission of Anaplasma marginale (Rickettsiales: Anaplasmataceae) by Dermacentor andersoni Stiles (Acari: Ixodidae) Compared to Mechanical Transmission by Stomoxys calcitrans (L.)(Diptera: Muscidae). Journal of Medical Entomology. 42(4):668-675.

VARIATION AMONG GEOGRAPHICALLY SEPARATED POPULATIONS OF DERMACENTOR ANDERSONI (ACARI: IXODIDAE) IN MIDGUT SUSCEPTIBILITY TO ANAPLASMA MARGINALE (RICKETTSIALLES: ANAPLASMATACEAE) - (Peer Reviewed Journal)

Scoles, G.A., Ueti, M., Palmer, G. 2005. Variation Among Geographically Separated Populations of Dermacentor andersoni (Acari: Ixodidae) in Midgut Susceptibility to Anaplasma marginale (Rickettsiales: Anaplasmataceae). Journal of Medical Entomology. 42(2):153-162.

VARIATION AMONG GEOGRAPHICALLY SEPARATED POPULATIONS OF DERMACENTOR ANDERSONI (ACARI: IXODIDAE) IN MIDGUT SUSCEPTIBILITY TO ANAPLASMA MARGINALE (RICKETTSIALES: ANAPLASMATACEAE) - (Peer Reviewed Journal)

Scoles, G.A., Ueti, M.W., Palmer, G.H. 2005. Variation among geographically separated populations of dermacentor andersoni (acari: ixodidae) in midgut susceptibility to anaplasma marginale (rickettsiales: anaplasmataceae). Journal of Medical Entomology. 42(2):153-162.

A PHYLOGENETIC ANALYSIS OF THE FRANCISELLA-LIKE ENDOSYMBIONTS OF DERMACENTOR TICKS - (Peer Reviewed Journal)

Scoles, G.A. 2004. Phylogenetic analysis of the Francisella-like endosymbionts of Dermacentor Ticks. 41:277-286.

EXPRESSION OF EQUI MEROZOITE ANTIGEN 2 DURING DEVELOPMENT OF BABESIA EQUI IN THE MIDGUT AND SALIVARY GLAND OF THE VECTOR TICK BOOPHILUS MICROPLUS - (Peer Reviewed Journal)

Ueti, M.W., G.H. Palmer, L.S. Kappmeyer, G.A. Scoles and D.P. Knowles. 2003. Expression of Equi Merozoite Antigen 2 during Development of Babesia equi in the Midgut and Salivary Gland of the vector tick Boophilus microplus. J. Clin. Micro. 41(12):5803-5809.