Projects

Identification and Enhancement of Seed-Based Biochemical Resistance in Crops to Aflatoxin Producing Pathogens Appropriated (D)   Accession Number: 409782

Aflatoxin Control Through Targeting Mechanisms Governing Aflatoxin Biosynthesis in Corn and Cottonseed Appropriated (D)   Accession Number: 409790

Ecological Basis for Aflatoxin Reduction Through Crop Management and Biological Control Appropriated (D)   Accession Number: 409880

Identification of Regulatory Genes in A. Flavus and A. Nidulans That Are Involved in Mycotoxin Production, Morphogenesis, and Virulence Specific Cooperative Agreement (S)   Accession Number: 416848

Publications

Predicted roles of the uncharacterized clustered genes in aflatoxin biosynthesis - (Peer Reviewed Journal) - (23-Sep-09)

Characterization of the Aspergillus ochraceoroseus aflatoxin/sterigmatocystin biosynthetic gene cluster - (Peer Reviewed Journal)

Cary, J.W., Ehrlich, K., Beltz, S.B., Harris Coward, P.Y., Klich, M.A. 2009. Characterization of the Aspergillus ochraceoroseus aflatoxin/sterigmatocystin biosynthetic gene cluster. Mycologia. 101(3):352-362.

Synthetic strategy of nonreducing iterative polyketide synthases and the origin of the classical ¿starter unit effect¿ - (Peer Reviewed Journal)

Crawford, J.M., Vagstad, A.L., Whitworth, K.P., Ehrlich, K., Townsend, C.A. 2008. Synthetic strategy of nonreducing iterative polyketide synthases and the origin of the classical ¿starter unit effect." ChemBioChem. 9(7):1019-1023.

Acyl-carrier protein - Phosphopantetheinyltransferase partnerships in fungal fatty acid synthases - (Peer Reviewed Journal)

Crawford, J.M., Vagstad, A.L., Ehrlich, K., Udwary, D.W., Townsend, C.A. 2008. Acyl-carrier protein - Phosphopantetheinyltransferase partnerships in fungal fatty acid synthases. ChemBioChem. 9(10):1559-1563.

Starter unit specificity directs genome mining of polyketide synthase pathways in fungi - (Peer Reviewed Journal)

Crawford, J.M., Vagstad, A.L., Ehrlich, K., Townsend, C.A. 2008. Starter unit specificity directs genome mining of polyketide synthase pathways in fungi. Bioorganic Chemistry. 36:16-22.

Use of Pyrosequencing to Quantify Incidence of a Specific Aspergillus flavus Within Complex Fungal Communities Associated with Commercial Cotton Crops - (Peer Reviewed Journal)

Das, M.K., Ehrlich, K., Cotty, P.J. 2008. Use of Pyrosequencing to Quantify Incidence of a Specific Aspergillus flavus Within Complex Fungal Communities Associated with Commercial Cotton Crops. Phytopathology. 98:282-288.

Biodiversity of Aspergillus Species in Some Important Agricultural Products - (Peer Reviewed Journal)

Perrone, G., Susca, A., Cozzi, G., Ehrlich, K., Varga, J., Frisvad, J.C., Meijer, M., Noonim, P., Mahakarnchanakul, W., Samson, R.A. 2007. Biodiversity of Aspergillus Species in Some Important Agricultural Products. Studies in Mycology 59:53-66.

Secondary Metabolite Profiling, Growth Profiles and Other Tools for Species Recognition and Important Aspergillus Mycotoxins - (Peer Reviewed Journal)

Frisvad, J.C., Larsen, T.O., De Vries, R., Meijer, M., Houbraken, J., Cabanes, F.J., Ehrlich, K., Samson, R.A. 2007. Secondary Metabolite Profiling, Growth Profiles and Other Tools for Species Recognition and Important Aspergillus Mycotoxins. Studies in Mycology 59:31-37.

Cloning and Characterization of the Aspergillus ochraceoroseus Aflatoxin Biosynthetic Gene Cluster - (Abstract) - (01-Mar-07)

Understanding the Genetics of Regulation of Aflatoxin Production and Aspergillus flavus Development - (Review Article)

Bhatnagar, D., Cary, J.W., Ehrlich, K., Yu, J., Cleveland, T.E. 2006. Understanding the Genetics of Regulation of Aflatoxin Production and Aspergillus flavus Development. Mycopathologia. 162:155-166.

Evolution of the Aflatoxin Gene Cluster - (Peer Reviewed Journal)

Ehrlich, K.C. 2006. Evolution of the Aflatoxin Gene Cluster. Mycotoxin Research. 22:9-15.

Aflatoxin-Producing Aspergillus Species from Thailand - (Peer Reviewed Journal)

Ehrlich, K., Kobbeman, K., Montalbano, B.G., Cotty, P.J. 2006. Aflatoxin-Producing Aspergillus Species from Thailand. International Journal of Food Microbiology. 114:153-159.

Polyketide Biosynthesis in Fungi - (Book/Chapter)

Ehrlich, K. 2007. Polyketide Biosynthesis in Fungi. In: Rimando, A.M. and Baerson, S.R., editors. Washington, DC: American Chemical Society. American Chemical Society Symposium Series. 955:68-80.

Analysis of Single Nucleotide Polymorphisms in Three Genes Shows Evidence for Genetic Isolation of Certain Aspergillus flavus Vegetative Compatibility Groups - (Peer Reviewed Journal)

Ehrlich, K., Montalbano, B.G., Cotty, P.J. 2007. Analysis of Single Nucleotide Polymorphisms in Three Genes Shows Evidence for Genetic Isolation of Certain Aspergillus flavus Vegetative Compatibility Groups. Federation of European Microbiological Societies Microbiology Letters. 268(2):231-236.

Aflatoxigenicity in Aspergillus: Molecular Genetics, Phylogenetic Relationships and Evolutionary Implications - (Review Article)

Cary, J.W., Ehrlich, K. 2006. Aflatoxigenicity in Aspergillus: molecular genetics, phylogenetic relationships and evolutionary implications. Mycopathologia. 162:167-177.

Regulatory Elements in Aflatoxin Biosynthesis - (Review Article)

Cary, J.W., Ehrlich, K., Kale, S.P., Calvo, A.M., Bhatnagar, D., Cleveland, T.E. 2006. Regulatory Elements in Aflatoxin Biosynthesis. Mycotoxin Research. 22(2):105-109.

Cladal Relatedness among Aspergillus Oryzae Isolates and Aspergillus Flavus S and L Morphotype Isolates - (Peer Reviewed Journal)

Chang, P.-K., Ehrlich, K., Hua, S.T. 2006. Cladal relatedness among Aspergillus oryzae isolates and Aspergillus flavus S and L morphotype isolates. International Journal of Food Microbiology. 108:172-177.

The Aflatoxin Biosynthesis Cluster Gene, Aflx, Encodes An Oxidoreductase Involved in Conversion of Versicolorin a to Sterigmatocystin - (Peer Reviewed Journal)

Cary, J.W., Ehrlich, K., Bland, J.M., Montalbano, B.G. 2005. The aflatoxin biosynthesis cluster gene, aflX, encodes an oxidoreductase involved in conversion of versicolorin A to sterigmatocystin. Applied and Environmental Microbiology. 72(2):1096-1100.

The Aflatoxin Biosynthesis Cluster Gene Hypa Is Required for Conversion of Versicolorin a to Sterigmatocystin - (Peer Reviewed Journal)

Ehrlich, K., Montalbano, B.G., Boue, S.M., Bhatnagar, D. 2005. An aflatoxin biosynthesis cluster gene encodes a novel oxidase required for conversion of versicolorin a to sterigmatocystin. Applied and Environmental Microbiology. 71:8963-8965.

Aflatoxin Biosynthesis Gene Clusters and Flanking Regions - (Peer Reviewed Journal)

Ehrlich, K.C., Yu, J., Cotty, P.J. 2005. Aflatoxin biosynthesis gene clusters and flanking regions. Journal of Applied Microbiology. 99:518-527.

The Aflatoxin Biosynthesis Cluster Gene Cypa Is Required for Aflatoxin G1 and G2 Formation - (Peer Reviewed Journal)

Ehrlich, K.C., Chang, P.-K., Yu, J., Cotty, P.J. 2004. Aflatoxin biosynthesis cluster gene cypA is required for G aflatoxin formation. Applied and Environmental Microbiology. 70(11):6518-6524.

Divergent Regulation of Aflatoxin Production at Acidic Ph by Two Aspergillus Strains - (Peer Reviewed Journal)

Ehrlich, K., Montalbano, B.G., Cotty, P.J. 2005. Divergent regulation of aflatoxin production at acidic pH by two Aspergillus strains. Mycopathologia. 159:579-581.

An Isolate of Aspergillus Flavus Used to Reduce Aflatoxin Contamination in Cottonseed Has a Defective Polyketide Synthase - (Peer Reviewed Journal)

Ehrlich, K., Cotty, P.J. 2004. An isolate of Aspergillus flavus used to reduce aflatoxin contamination in cottonseed has a defective polyketide synthase. Applied Microbiology and Biotechnology. Available: http://springerlink.metapress.com/link.asp?id=3u5j6w5nnmj3dve8.

Aspergillus Genomics: Understanding Fungal Ecology and Aflatoxin Production - (Abstract)

Bhatnagar, D., Yu, J., Ehrlich, K., Cleveland, T.E. Aspergillus genomics: Understanding fungal ecology and aflatoxin production [abstract]. International Union of Pure and Applied Chemistry (IUPAC) Symposium on Mycotoxins and Phycotoxins, May 17-21, 2004, Bethesda, Maryland.

Aflatoxin-Producing Aspergillus Species from Thailand - (Abstract)

Ehrlich, K., Montalbano, B.G., Kobbeman, K., Cotty, P.J. 2004. Aflatoxin-producing Aspergillus species from Thailand. Proceedings of American Society for Microbiology Annual Meeting. O-015:463.

The Clustered Pathway Genes in Aflatoxin Biosynthesis - (Review Article)

Yu, J., Chang, P.-K., Ehrlich, K., Cary, J.W., Bhatnagar, D., Cleveland, T.E., Payne, G.A., Linz, J.E., Woloshuk, C.P., Bennett, J.W. 2004. The clustered pathway genes in aflatoxin biosynthesis. Applied And Environmental Microbiology. 70(3):1253-1262.

Characterization of the Complete Aflatoxin Pathway Gene Cluster in Aspergillus Parasiticus - (Abstract)

Yu, J., Chang, P.-K., Ehrlich, K., Cary, J.W., Bhatnagar, D., Cleveland, T.E. 2003. Characterization of the complete aflatoxin pathway gene cluster in Aspergillus parasiticus. Proceedings of USDA-ARS Aflatoxin/Fumonisin Elimination and Fungal Genomics Workshop, October 13-15, 2003, Savannah, Georgia.

New Insights into Ph Regulation of Aflatoxin Production by Aspergillus Species - (Abstract)

Ehrlich, K., Cotty, P.J. 2003. New insights into pH regulation of aflatoxin production by Aspergillus species. XXII Fungal Genetics Conference Proceedings. Abstract No. 201. p. 283.

Molecular Genetic Analysis of Aflatoxin Biosynthesis and Its Application to Understanding the Biological Role of Aflatoxin - (Review Article)

Bhatnagar, D., Ehrlich, K., Cleveland, T.E. 2003. Molecular genetic analysis of aflatoxin biosynthesis and its application to understanding the biological role of aflatoxin. Applied Microbiology and Biotechnology. 61:83-93.

Aflatoxin Biosynthesis - (Review Article)

Yu, J., Bhatnagar, D., Ehrlich, K. 2002. Aflatoxin biosynthesis. Revista Iberoamericana De Micologia. 19:191-200.