Paul Jacques
(Tufts University)
Human Nutrition Research Center on Aging
(This person is no longer with ARS)
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The Development of the Mediterranean-Style Dietary Pattern Score and Its Application to the American Diet in the Framingham Offspring Cohort
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Rumawas, M.E., Dwyer, J.T., Mckeown, N.M., Meigs, J.B., Rogers, G., Jacques, P. 2009. The Development of the Mediterranean-Style Dietary Pattern Score and Its Application to the American Diet in the Framingham Offspring Cohort. Journal of Nutrition. 139:1150-1156.
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Effect of vitamin E and SNPs at cytokine genes on cytokine production in the elderly
- (Abstract)
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Belisle, S.E., Leka, L.S., Delgado-Lista, J., Jacques, P., Ordovas, J.M., Meydani, S. 2009. Effect of vitamin E and SNPs at cytokine genes on cytokine production in the elderly. Journal of Federation of American Societies for Experimental Biology. 23:110.2.2.
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SNPs at IL-2 and IL-10 genes are associated with respiratory infection in the elderly and may modulate the effect of vitamin E on lower respiratory infections in elderly women
- (Abstract)
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Belisle, S.E., Hamer, D.H., Leka, L.S., Dallal, G., Delgado-Lista, J., Fine, B.C., Jacques, P., Ordovas, J.M., Meydani, S. 2009. SNPs at IL-2 and IL-10 genes are associated with respiratory infection in the elderly and may modulate the effect of vitamin E on lower respiratory infections in elderly women. Journal of Federation of American Societies for Experimental Biology. 23:221.1.
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Cross-sectional association of dietary patterns with insulin resistance phenotypes among adults without diabets in the Framingham Offspring Study
- (Peer Reviewed Journal)
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Liu, E., Mckeown, N.M., Newby, P., Meigs, J.B., Vasan, R.S., D'Agostino, R.B., Quatromoni, P., Jacques, P. 2009. Cross-sectional association of dietary patterns with insulin resistance phenotypes among adults without diabets in the Framingham Offspring Study. British Journal of Nutrition. 16:1-8.
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Association of lifestyle factors with abdominal subcutaneous and visceral adiposity: The Framingham Heart Study
- (Peer Reviewed Journal)
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Molenaar, E., Massaro, J., Jacques, P., Pou, K., Ellison, R., Hoffmann, U., Pencina, K., Shadwick, S., Vasan, R., O'Donnell, C., Fox, C. 2009. Association of lifestyle factors with abdominal subcutaneous and visceral adiposity: The Framingham Heart Study. Diabetes Care. 32(3):505-510.
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Plasma 25-Hydroxyvitamin D is Associated with Markers of the Insulin Resistance Phenotype in Non-diabetic Adults
- (Peer Reviewed Journal)
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Liu, E., Meigs, J.B., Pittas, A.G., Mckeown, N.M., Economos, C.D., Booth, S.L., Jacques, P. 2009. Plasma 25-Hydroxyvitamin D is Associated with Markers of the Insulin Resistance Phenotype in Non-diabetic Adults. Journal of Nutrition. 139:329-334.
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Cytokine response to vitamin E supplementation is dependent on pre-supplementation cytokine levels
- (Peer Reviewed Journal)
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Belisle, S.E., Leka, L.S., Dallal, G., Jacques, P., Lista, J., Ordovas, J.M., Meydani, S. 2008. Cytokine response to vitamin E supplementation is dependent on pre-supplementation cytokine levels. Biofactors. 33:191-200.
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Not all cases of neural-tube defect can be prevented by increasing the intake of folic acid
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Heseker, H.B., Mason, J.B., Selhub, J., Rosenberg, I., Jacques, P. 2009. Not all cases of neural-tube defect can be prevented by increasing the intake of folic acid. British Journal of Nutrition. 102:173-180.
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Alternative Approaches to the Calculation of Nutrient Density
- (Review Article)
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Kennedy, E., Racsa, P., Dallal, G., Lichtenstein, A.H., Goldberg, J., Jacques, P., Hyatt, R. 2008. Alternative Approaches to the Calculation of Nutrient Density. Nutrition Reviews. 66(12):703-709.
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Effect of Vitamin K Supplementation on Insulin Resistance in Older Men and Women
- (Peer Reviewed Journal)
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Yoshida, M., Jacques, P., Meigs, J., Saltzman, E., Shea, K., Gundberg, C., Dawson-Hughes, B., Dallal, G., Booth, S.L. 2008. Effect of Vitamin K Supplementation on Insulin Resistance in Older Men and Women. Diabetes Care. 31:2092-2096.
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Contemporary Trends in Dyslipidemia in the Framingham Heart Study
- (Peer Reviewed Journal)
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Ingelsson, E., Massaro, J.M., Sutherland, P., Jacques, P., Levy, D., D'Agostino, R.B., Vasan, R.S., Robins, S.J. 2009. Contemporary Trends in Dyslipidemia in the Framingham Heart Study. Archives of Internal Medicine. 169(3):279-286.
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Magnesium Intake and Prevalence of Metabolic Syndrome in Older Adults
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Mckeown, N., Jacques, P., Xinli, Z., Wenyen, J., Sayhoun, N. 2008. Magnesium Intake and Prevalence of Metabolic Syndrome in Older Adults. European Journal of Nutrition. 47:210-216.
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Phylloquinone intake is associated with greater insulin sensitivity and glycemic status in adult men and women
- (Peer Reviewed Journal)
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Yoshida, M., Booth, S.L., Megis, J.B., Saltzman, E., Jacques, P. 2008. Phylloquinone intake is associated with greater insulin sensitivity and glycemic status in adult men and women. American Journal of Clinical Nutrition. 88:210-215.
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Plasma B vitamins, homocysteine and their relation with bone loss and hip fracture in elderly men and women
- (Peer Reviewed Journal)
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Mclean, R.R., Jacques, P., Selhub, J., Fredman, L., Tucker, K., Samelson, E.J., Kiel, D.P., Cupples, L.A., Hannan, M.T. 2008. Plasma B vitamins, homocysteine and their relation with bone loss and hip fracture in elderly men and women. Journal of Clinical Endocrinology and Metabolism. 93(6):2206-2212.
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Experts stress both wellness and amenity aspects of food and nutrition services in assisted living facilities for older adults
- (Peer Reviewed Journal)
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Chao, S.Y., Dwyer, J.T., Houser, R.F., Jacques, P., Tennstedt, S. 2008. Experts stress both wellness and amenity aspects of food and nutrition services in assisted living facilities for older adults. Journal Of The American Dietetic Association. 108:1654-1661.
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Practitioners¿ Opinions on Food and Nutrition Care Indicators (FANCI) in Assisted Living Facilities for Older Adults
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Chao, S.Y., Dwyer, J.T., Houser, R.F., Tennstedt, S., Jacques, P. 2008. Practitioners¿ Opinions on Food and Nutrition Care Indicators (FANCI) in Assisted Living Facilities for Older Adults. Journal Of The American Dietetic Association. 108(9):1526-1531.
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Will Increasing Folic Acid in Fortified Grain Products Further Reduce Neural Tube Defects without Causing Harm?: Consideration of the Evidence
- (Other)
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Morris, M.S., Jacques, P., Rosenberg, I., Selhub, J. 2008. Will Increasing Folic Acid in Fortified Grain Products Further Reduce Neural Tube Defects without Causing Harm?: Consideration of the Evidence. Pediatric Research. 63(4):450.
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Phylloquinone intake is associated with glucose metabolism in middle- and older-aged men and women
- (Abstract)
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Yoshida, M., Booth, S.L., Meigs, J.B., Saltzman, E., Jacques, P. 2008. Phylloquinone intake. Journal of Federation of American Societies for Experimental Biology. 22:1106.4.
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Response to Quinlivan: Post-fortification, folate intake in vitamin B12 deficiency is positively related to homocysteine and methylmalonic acid
- (Other)
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Morris, M.S., Jacques, P., Selhub, J. 2008. Response to Quinlivan: Post-fortification, folate intake in vitamin B12 deficiency is positively related to homocysteine and methylmalonic acid. Proceedings of the National Academy of Sciences. 105(5):E8.
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Plasma Pyridoxal 5'-phosphate (PLP) in the United States population: the National Health and Nutrition Examination Survey, 2003-2004
- (Peer Reviewed Journal)
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Morris, M.S., Picciano, M.F., Jacques, P., Selhub, J. 2008. Plasma Pyridoxal 5'-phosphate (PLP) in the United States population: the National Health and Nutrition Examination Survey, 2003-2004. American Journal of Clinical Nutrition. 87(5):1446-1454.
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Relationship between the 19 base pair deletion polymorphism in DHFR and unmetabolized folic and in plasma and RBC folate
- (Abstract)
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Kalmbach, R., Choumenkovitch, S., Jacques, P., D'Agostino, R.B., Troen, A., Selhub, J. 2008. Relationship between the 19 base pair deletion polymorphism in DHFR and unmetabolized folic and in plasma and RBC folate. Federation of American Societies for Experimental Biology Journal. 22:296.4.
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Dietary patterns and the insulin resistance phenotype among non-diabetic adults
- (Abstract)
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Liu, E., McKeown, N.M., Newby, P., Meigs, J.B., Vasan, R.S., D'Agostino, R.B., Quatromoni, P., Jacques, P. 2008. Dietary patterns and the insulin resistance phemotype among non-diabetic adults. Experimental Biology. Abstract No. 3088.
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In vitamin B12 deficiency, higher serum folate is assoicated with increased total homocysteine (tHcy) and methlmalonic acid (MMA) concentrations
- (Peer Reviewed Journal)
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Selhub, J., Morris, M.S., Jacques, P. 2007. In vitamin B12 deficiency, higher serum folate is assoicated with increased total homocysteine (tHcy) and methlmalonic acid (MMA) concentrations. Proceedings of the National Academy of Sciences. 104(50):19995-20000.
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Vitamin D Deficiency and the Risk of Cardiovascular Disease
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Wang, T., Pencina, M.J., Booth, S.L., Jacques, P., Ingelsson, E., Lanier, K., Benjamin, E.J., D'Agostino, R.B., Wolf, M., Vasan, R.S. 2008. Vitamin D Deficiency and the Risk of Cardiovascular Disease. Circulation. 117:503-511.
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Dietary carbohydrates and cardiovascular disease risk factors in the Framingham Offspring Cohort
- (Peer Reviewed Journal)
- (01-Oct-07)
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Genetic and non-genetic correlates of vitamins K and D
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Shea, K.M., Benjamin, E.J., Dupuis, J., Massaro, J.M., Jacques, P., D'Agostino, R.B., Ordovas, J.M., O'Donnell, C.J., Dawson-Hughes, B., Vasan, R., Booth, S.L. 2009. Genetic and non-genetic correlates of vitamins K and D. European Journal of Clinical Nutrition. 63:458-464.
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Whole-grain intake and cereal fiber associated with lower abdominal adiposity in older adults
- (Abstract)
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Mckeown, N.M., Yoshida, M., Shea, K., Booth, S.L., Lichtenstein, A.H., Saltzman, E., Jacques, P. 2007. Whole-grain intake and cereal fiber associated with lower abdominal adiposity in older adults. Annual Scientific Meeting NAASO, The Obesity Society, October 20-24, 2007, New Orleans, LA. 15:A37.
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Surrogate markers of insulin resistance associated with consumption of sugar sweetened soft drinks and fruit juice in the Framingham Offspring Cohort
- (Peer Reviewed Journal)
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Yoshida, M., Mckeown, N.M., Megis, J.B., Rogers, G., Saltzman, E., D'Agostino, R., Jacques, P. 2007. Surrogate markers of insulin resistance associated with consumption of sugar sweetened soft drinks and fruit juice in the Framingham Offspring Cohort. Journal of Nutrition. 137:2121-2127.
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The Food and Nutrition Care Indicators (FANCI): Experts¿ views on quality indicators for food and nutrition services in assisted living facilities for elders
- (Peer Reviewed Journal)
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Chao, S.Y., Houser, R.F., Tennstedt, S., Jacques, P., Dwyer, J.T. 2007. The Food and Nutrition Care Indicators (FANCI): Experts¿ views on quality indicators for food and nutrition services in assisted living facilities for elders. Journal Of The American Dietetic Association. 107(9)1590-1598.
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The 2005 Dietary Guidelines for Americans and Risk of Metabolic Syndrome
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Fogli-Cawley, J., Dwyer, J., Saltzman, E., Mccullough, M., Troy, L.M., Megis, J., Jacques, P. 2007. The 2005 Dietary Guidelines for Americans and Risk of Metabolic Syndrome. American Journal of Clinical Nutrition. 86:1193-1201.
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A Temporal Association between Folic Acid Fortification and a Rise in Colorectal Cancer Rates May be Illuminating Important Biological Principles: a Hypothesis
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Mason, J.B., Dickstein, A., Jacques, P., Haggarty, P., Selhub, J., Dallal, G., Rosenberg, I. 2007. A temporal association between folic acid fortification and a rise in colorectal cancer rates may be illuminating important biological principles: a hypothesis. Cancer Epidemiology Biomarkers and Prevention. 16:1.
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Serum zinc and pneumonia in nursing home elderly
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Meydani, S., Barnett, J.B., Dallal, G., Fine, B.C., Jacques, P., Leka, L.S., Hamer, D.H. 2007. Serum zinc and pneumonia in nursing home elderly. American Journal of Clinical Nutrition. 86:1167-73.
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Dihydrophylloquinone intake is associated with low bone mineral density in men and women
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Troy, L.M., Jacques, P., Hannan, M.T., Kiel, D.P., Lichtenstein, A.H., Kennedy, E.T., Booth, S.L. 2007. Dihydrophylloquinone intake, a marker of a non-healthy dietary pattern, is associated with low bone mineral density in men and women. American Journal of Clinical Nutrition. 86:504-508.
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Associations of plasma natriuretic peptide, adrenomedullin, and homocysteine levels with alterations in arterial stiffness: The Framingham Heart Study
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Levy, D., Hwang, S., Katalar, A., Benjamin, E.J., Vasan, R.S., Parise, H., Larson, M.G., Wang, T.J., Selhub, J., Jacques, P., Vita, J.A., Keyes, M.J., Mitchell, G.F. 2007. Associations of plasma natriuretic peptide, adrenomedullin, and homocysteine levels with alterations in arterial stiffness: The Framingham Heart Study. Circulation. 115:3069-3085.
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Dietary Linolenic Acid Intake Is Positively Associated with Five-Year Change in Eye Lens Nuclear Density
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Lu, M., Taylor, A., Chylack, L.T., Rogers, G., Hankinson, S., Willett, W., Jacques, P. 2007. Dietary linolenic acid intake is positively associated with five-year change in eye lens nuclear density. Journal of Nutrition. 26(2):133-140.
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The 2005 Dietary Guidelines for Americans & Insulin Resistance in the Framingham Offspring Cohort
- (Peer Reviewed Journal)
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Fogli-Cawley, J., Dwyer, J., Saltzman, E., Mccollough, M., Troy, L.M., Meigs, J., Jacques, P. 2007. The 2005 Dietary Guidelines for Americans & Insulin Resistance in the Framingham Offspring Cohort. Diabetes Care. 304(4):817-822.
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Intake of zinc and antioxidant micronutrients and early age-related maculopathy lesions
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Morris, M., Jacques, P., Chylack, L.T., Hankinson, S.E., Willett, W.C., Taylor, A. 2007. Intake of zinc and antioxidant micronutrients and early age-related maculopathy lesions. Ophthalmic Epidemiology. 14:288-298.
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Plasma Homocysteine and Carotid Artery Intima-Media Thickness: Site-Specific Associations in the Framingham Offspring Cohort
- (Abstract)
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Dietrich, M., Jacques, P., Polak, J., Pencina, M., Evans, J., Selhub, J., Vasan, R., D'Agostino, R. 2006. Plasma Homocysteine and Carotid Artery Intima-Media Thickness: Site-Specific Associations in the Framingham Offspring cohort. Federation of American Societies of Experimental Biology. Abstract no. 660.9.
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Mediterranean-style dietary pattern is associated with surrogate measures of insulin resistance in the Framingham Offspring Cohort
- (Abstract)
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Rumawas, M.E., Mckeown, N., Rogers, G., Dwyer, J.T., Meigs, J., Jacques, P. 2007. Mediterranean-style dietary pattern is associated with surrogate measures of insulin resistance in the Framingham Offspring Cohort. Experimental Biology/FASEB Journal. 21(5):6.
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Use of the affinity/HPLC method for quantitative estimation of folic acid enriched cereal grain products
- (Peer Reviewed Journal)
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Poo-Prieto, R., Haytowitz, D.B., Holden, J.M., Rogers, G., Choumenkovitch, S.F., Jacques, P.F., Selhub, J. 2006. Use of the affinity/HPLC method for quantitative estimation of folic acid enriched cereal grain products. Journal of Nutrition. 136:3079-3083.
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Multiple Biomarkers for the Prediction of First Major Cardiovascular Events and Death
- (Peer Reviewed Journal)
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Wang, T.J., Gona, P., Larson, M.G., Toffler, G.H., Levy, D., Newton-Cheh, C., Jacques, P., Rifai, N., Selhub, J., Robins, S.J., Benjamin, E.J., D'Agostiono, R.B., Vasan, R.S. 2006. Multiple Biomarkers for the Prediction of First Major Cardiovascular Events and Death. New England Journal of Medicine. 355(25): 2631-9.
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The 2005 Dietary Guidelines for Americans Adherence Index: Development and Application
- (Peer Reviewed Journal)
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Fogli-Cawley, J.J., Dwyer, J.T., Saltzman, E., Mccullough, M.L., Troy, L.M., Jacques, P. 2006. The 2005 dietary guidelines for americans adherence index: development and application. Journal of Nutrition. 136:2908-2915.
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Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification
- (Peer Reviewed Journal)
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Morris, M.S., Jacques, P., Rosenberg, I., Selhub, J. 2007. Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification. American Journal of Clinical Nutrition. 85(1):193-200.
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Are Healthy Diets that follow The 2005 Dietary Guidelines for Americans (DGA) associated with Bone Mineral Density (BMD) in men and women?
- (Abstract)
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Troy, L.M., Hannan, M.T., Booth, S.L., Kennedy, E.T., Fogli, J., Kiel, D.P., Jacques, P. 2006. Are Healthy Diets that follow The 2005 Dietary Guidelines for Americans (DGA) associated with Bone Mineral Density (BMD) in men and women?. Journal of Bone and Mineral Research. 21(1):p.S272.
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Does gamma-tocopherol play a role in the primary prevention of heart disease and cancer? A review
- (Review Article)
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Dietrich, M., Traber, M.G., Jacques, P., Cross, C.E., Hu, Y., Block, G. 2006. Does gamma-tocopherol play a role in the primary prevention of heart disease and cancer? A review. Journal of the American College of Nutrition. 25(4): 292-299.
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Dietary Fiber and Whole Grain Intake Lessen Gains in Weight and Waist Circumference in Normal Weight Individuals
- (Abstract)
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Quatromoni, P., Mckeown, N., Rogers, G., Jacques, P. 2006. Dietary Fiber and Whole Grain Intake Lessen Gains in Weight and Waist Circumference in Normal Weight Individuals. Annual Scientific Meeting NAASO, The Obesity Society. October 20-24, 2006: Boston, MA. Abstract no. 9-OR.
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Consumption of sugar-sweetened soft-drink and fruit juice beverages differentially associated with glucose-related measures
- (Abstract)
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Yoshida, M., Mckeown, N., Meigs, J., Rogers, G., Saltzman, E., Jacques, P. 2006. Consumption of sugar-sweetened soft-drink and fruit juice beverages differentially associated with glucose-related measures. Annual Scientific Meeting NAASO, The Obesity Society. October 20-24, 2006: Boston, MA. Abstract no. 68-OR.
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Dietary fiber is related to metabolic risk factors in the Framingham Offspring Cohort
- (Proceedings/Symposium)
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Mckeown, N., Meigs, J., Rogers, G., Saltzman, E., Liu, S., Jacques, P. 2006. Dietary fiber is related to metabolic risk factors in the Framingham Offspring Cohort. Annual Scientific Meeting NAASO, The Obesity Society. October 20-24, 2006: Boston, MA. Obesity. 14(9):A22.
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Dietary Choline and Betanine Assessed by Food-Frequency Questionnaire in Relation to Plasma Total Homocysteine Concentration in the Framingham Offspring Study
- (Peer Reviewed Journal)
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Cho, E., Zeisel, S.H., Jacques, P.F., Selhub, J., Dougherty, L., Colditz, G.A., Willett, W.C. 2006. Dietary Choline and Betanine Assessed by Food-Frequency Questionnaire in Relation to Plasma Total Homocysteine Concentration in the Framingham Offspring Study. American Journal of Clinical Nutrition. 83(4):905-911.
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Nutrient Density: Making the Pyramid Come Alive
- (Abstract)
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Kennedy, E., Racsa, P., Dallal, G.E., Jacques, P.F., Lichtenstein, A.H., Goldberg, J., Wilde, P., Hyatt Jr, R.R. 2006. Nutrient Density: Making the Pyramid Come Alive. Federation of American Societies for Experimental Biology Conference. 20: A1311.
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The Cost of a Healthful Diet
- (Abstract)
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Kennedy, E., Racsa, P., Wilde, P., Dallal, G., Jacques, P., Lichtenstein, A.H., Goldberg, J., Hyatt Jr, R.R. 2006. The Cost of a Healthful Diet. Federation of American Societies for Experimental Biology Conference. San Francisco, CA: April 105, 2006. Abstract no. 401.5.
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Dihydrophylloquinone Intake, a Marker of Poor Diet, Is Associated with Low Bone Mineral Density in Men
- (Abstract)
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Troy, L.M., Jacques, P., Hannan, M.T., Kiel, D.P., Lichtenstein, A.H., Kennedy, E.T., Booth, S.L. 2006. Dihydrophylloquinone intake, a marker of poor diet, is associated with low bone mineral density in men. Experimental Biology 2006 Annual Meeting. April 1-5, 2006. San Francisco, CA. Abstract no. 646.2.
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The use of blood concentrations of vitamins and their respective functional indicators to define folate and vitamin B12 status
- (Proceedings/Symposium)
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Selhub, J., Jacques, P., Dallal, G., Choumenkovitch, S., Rogers, G. 2008. The use of blood concentrations of vitamins and their respective functional indicators to define folate and vitamin B12 status. Food and Nutrition Bulletin. 29(2)(Suppl):S67-S73.
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Dietary glycemic index and carbohydrate in relation to early
age-related macular degeneration
- (Peer Reviewed Journal)
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Chiu, C., Hubbard, L.D., Armstrong, J., Rogers, G., Jacques, P.F., Chylack, L.T., Hankinson, S.E., Willett, W.C., Taylor, A. 2006. Dietary glycemic index and carbohydrate in relation to early age-related macular degeneration. American Journal of Clinical Nutrition. 83(4):880-6.
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Dose-Dependent Effects of Folic Acid on Blood Concentrations of Homocysteine: a Meta-Analysis of the Randomized Trials
- (Review Article)
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Mason, J.B., Jacques, P.F., Rosenberg, I.H. 2005. Dose-dependent effects of folic acid on blood concentrations of homocysteine: a meta-analysis of the randomized trials. American Journal of Clinical Nutrition. 82(4):806-812.
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Homocysteine & Cognitive Performance in the Framingham Offspring Study: Age Is Important
- (Peer Reviewed Journal)
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Elias, M.F., Sullivan, L.M., D'Agostino, R.B., Elias, P.K., Jacques, P.F., Selhub, J., Seshadri, S., Au, R., Beiser, A., Wolf, P.A. 2005. Homocysteine & Cognitive Performance in the Framingham Offspring Study: Age is Important. American Journal of Epidemiology. 162(7):644-653.
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Tea Variety and Brewing Techniques Influence Flavonoid Content of Black Tea
- (Peer Reviewed Journal)
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Peterson, J., Dwyer, J., Jacques, P., Rand, W., Prior, R., Chiu, K. 2004. Tea variety and brewing techniques influence flavonoid content of black tea. Journal of Food Composition and Analysis. 17(3-4):397-405.
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A Common Polymorphism in the Methylenetetrahydrofolate Reductase (Mthfr) Gene Is Associated with Quantitative Ultrasound in Those with Low Plasma Folate
- (Peer Reviewed Journal)
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Mclean, R.R., Karasik, D., Selhub, J., Tucker, K., Ordovas, J.M., Russo, G.T., Cupples, A., Jacques, P., Kiel, D.P. 2004. A common polymorphism in the methylenetetrahydrofolate reductase (mthfr) gene is associated with quantitative ultrasound in those with low plasma folate. Journal of Bone and Mineral Research. 19:410-418.
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ARS News Articles
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