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Research directed towards;
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Using a molecular approach to gain fundamental understanding of the regulation of aflatoxin biosynthesis at the gene level.
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Characterization of antifungal compounds and genes governing production of antifungal compounds for use in biotechnological applications to control toxin-producing fungi or other fungi that reduce the quality and safety of foods and feeds.
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Elucidation of the mechanisms governing expression of genes/enzymes which govern aflatoxin synthesis during the plant-fungus interaction.
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Manipulation of agroecosystems involving complex interactions between the toxin-producing fungus, other endemic microflora and the crop plant to reduce levels of fungus and/or toxin in field environments.
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Characterization of the mechanisms of induction of isoflavonoids in legumes and phytoestrogen activities of these compounds in animal systems.
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Integration of research information into practical procedures for assuring a safe, domestic supply of food and feed.