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One-in-three girls and one-in-four boys had body fat levels considered obese for adults, according to a study of more than 600 children and teens living in the Houston area. That's a big jump from 20 years ago when only one-in-six girls and boys exceeded the obesity threshold for adults32 percent fat for women and 25 percent fat for men. The study, still ongoing, also found differences among white, black and Hispanic youths. Hispanic youths had the highest average body fat32 percent for girls and 24 percent for boys. White girls had the lowest average body fat26 percentamong the females. And black boys averaged the lowest19 percentamong the males. All subjects were measured by two highly accurate methods for assessing body composition: dual energy x-ray absorptiometry (DEXA) and emissions of potassium-40, a radioactive form of the element occurring naturally in the body in tiny amounts. This is the only study worldwide to assess fat and lean composition of children in different ethnic and racial groups. When complete, it should produce data on 1,000 childrenenough for developing charts that show normal ranges of body composition similar to the height and weight growth charts in pediatricians' offices.
Children's Nutrition Research Center, Houston, TX
Kenneth J. Ellis, (713) 798-7132
Black children start their growth spurt two to five years earlier than white or Hispanic children. This finding from a study of more than 600 children and teens points to the need to customize dietary recommendations for different ethnic groups to provide the protein and minerals for children when they need them. Black girls and boys tend to grow taller and heavier and mature faster than white or Hispanic children. At age 6, black girls begin adding significantly more muscle and bone than white or Hispanic girls, while these two groups wait until around age eight or nine for their growth spurt. Black boys begin to outpace white and Hispanic boys at age seven and grow even faster at age 12, when white and Hispanic boys are beginning their growth spurts. Current data on changes in body compositionfat, muscle and boneduring childhood were developed from data gathered in the 1950s, 60s and 70s on white children only. And they only give an average value for different ages. This ongoing study of boys and girls ages three to 18 aims to develop body composition charts showing the range of normal growth patterns among the major ethnic groups in this country. It shows that today's youths are bigger and taller than those of three to four decades ago along with having more body fat.
Children's Nutrition Research Center, Houston, TX
Kenneth J. Ellis, (713) 798-7132
Black adolescent girls had lower aerobic capacity than their white counterparts during a treadmill test, even though both ethnic groups had the same amount of body fat. Researchers conducted the study of 93 girls, ages 11 to 16, because of scanty information on the physical fitness of U.S. adolescents of different ethnic origins. Researchers measured peak oxygen consumptionan indicator of fitness known as VO2maxin 40 black girls and 53 white girls while they ran on a treadmill to the point of exhaustion. The black girls consumed 17 percent less oxygen than the white girls during the test and reached exhaustion nearly a minute earlier8.5 versus 9.4 minutes. Blood tests showed that hemoglobinthe oxygen-carrying molecule in red blood cellswas six percent lower in the black girls. Studies done in other countries suggest that ethnicity contributes to differences in aerobic fitness. Researcher don't yet have an explanation but suspect both genetics and lifestyle contribute to the differences. They are currently analyzing data they collected on the girls' body composition and resting metabolic rate for clues.
Children's Nutrition Research Center, Houston, TX
William W. Wong, (713) 798-7168
James M. Pivarnik (formerly ARS), (517) 353-3520
Older people's need for dietary protein markedly differed in two studiesindicating that more and larger studies are needed to resolve the question of protein requirements after age 50. A two-week study of 12 men and women in their late fifties, sixties and seventies suggests that the recommended dietary protein allowance (RDA) for people over age 50 may need to be adjusted upwards to 1.0 to 1.25 grams per kilogram of body weight each day (g/kg/d). The current RDA0.8 g/kg/dis the same as for younger adults, because the data on older people has been too scanty to establish a separate requirement. In this study, conducted at the ARS center in Boston, researchers calculated the amount of protein volunteers needed, using a formula adopted by the World Health Organization (WHO) in 1985. On average, the volunteers required a little more than the current RDAabout 1.0 g/kg/djust to replace the protein they excreted daily. The researchers also recalculated protein requirements for three earlier studies using the newer WHO formula and got nearly the same estimatean average of 0.9 g/kg/d. Their suggested 1.0 to 1.25 g/kg/d would cover those who require more than average. By contrast, all 14 women in a seven-week study stayed in balance while getting the RDA, suggesting that 0.8 g/kg/day is adequate. The women were between 51 and 70 years old. Conducted at the ARS center in Grand Forks, ND, this study differed from the Boston study in several ways. Most importantly, these diets provided more calories per kilogram of body weight. When calorie intake is too low to maintain body weight, people will burn protein to supply energy and thus appear to need more than they actually do to renew tissues. Larger studies need to be done to resolve the question of protein requirements after age 50.
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts, Boston, MA
Wayne W. Campbell (formerly ARS), (814) 865-3453
Grand Forks Human Nutrition Research Center, Grand Forks, ND
Janet Hunt, (701) 795-8328
Vitamin E, vitamin A and two other antioxidantslutein and zeaxanthinhave been found in the eyes' lenses, suggesting they may help protect against the formation of cataracts. Analyzing both healthy and cataract-clouded human lenses removed during surgery, researchers found significant levels of vitamins E and A, lutein and zeaxanthin. These latter two compounds are carotenoidsplant pigments related to beta caroteneand are abundant in yellow and dark green leafy vegetables, such as spinach, broccoli and kale. No other carotenoids, including beta carotene and lycopenetwo major carotenoids in human bloodwere found in the lenses. Population studies have shown a relationship between carotenoid or vitamin A levels in the blood and a lower incidence of cataracts. Of the 31 lenses analyzed, those removed from Asian Indians, who traditionally eat a lot of vegetables, had significantly higher levels of the antioxidants than those from Americans. Among the American lenses, antioxidant levels differed significantly, possibly reflecting a wide difference in vegetable intake among Americans.
Jean Mayer Human Nutrition Research Center on Aging at Tufts, Boston, MA
Kyung-Jin Yeum, (617) 556-3128
Obstetricians may someday monitor pregnant women's water weight gains using harmless electrical current. A study by scientists with ARS and the University of California at Berkeley may be the first to explore this specialized use of a technique known as bioimpedance spectroscopy, or BIS. During pregnancy, water accounts for most weight gain. But water buildup outside cellsextracellular watercan lead to edema for the mother-to-be. This sometimes painful swelling can raise blood pressure and cause other complications. In tests of 10 pregnant women, aged 20 to 37, the researchers found that BIS is faster and easier than options that require drinking or injecting fluid containing a tracer. A BIS measurement also is just as accurate, takes only two minutes and requires no blood samples, unlike tracer methods. BIS sends a harmless sweep of electricity through electrodes at the hand and foot. It distinguishes differences in resistance, as the electricity travels easily through water or is impeded by cell membranes. A computer converts these measurements into estimates of total water in the body, and water outside and inside cells. Xitron Technologies, Inc., San Diego, developers of the BIS instrument used in the experiment, collaborated with ARS in the study.
Western Human Nutrition Research Center, San Francisco, CA
Marta D. Van Loan, (415) 556-5729
Children's Nutrition Research Center, Houston, TX
William W. Wong, (713) 798-7168

A daily dose of the blue-green algae Spirulina may help prevent cancer of the mouth, a study shows. The finding could benefit people in developing countries where the algae is cheaper than vitamins. After one year of consuming only one gram of the algae daily, 45 percent of the volunteers had complete regression of the thick, white, pre-cancerous patches in the mouth known as leukoplakia. Taking in to account those volunteers who showed significant improvement raised the figure to 57 percent who benefitted from Spirulina. That compared to seven percent of those who got a placebo. The studythe first human evaluation of the cancer-preventive potential of Spirulinawas coordinated by an ARS researcher and conducted in southwestern India where the incidence of leukoplakia is high. The researchers tested Spirulina because it is an inexpensive source of beta carotene and related carotenoids in many developing countries. In other research, the algae has inhibited oral cancer in animal studies, while beta carotene or vitamin A supplements have reversed pre-cancerous conditions in people's mouths. Cancer of the mouth and of the cervixwhich has the same kind of mucus membraneis on the rise worldwide.
Beltsville Human Nutrition Research Center, Beltsville, MD
Padmanabhan P. Nair, (301) 504-8145
Measuring blood levels of the amino acid homocysteine only after an overnight fast could miss nearly half of the people with elevated levels. Research has linked high homocysteine levels to increased risk of heart disease and stroke. A second measurementtaken after a dose of another amino acid, methionineis needed to identify all cases, according to a study of 247 volunteers. That's because some people have a low tolerance for methionine and convert it rapidly to homocysteine, which raises blood levels. High blood levels of homocysteine may be damaging to arteries. Researchers found that the test done after overnight fasting failed to identify nearly half of the high-homocysteine cases. These cases were detected only after volunteers got a dose of methionine. Both tests are needed because three vitamins are involved in homocysteine metabolism. The overnight fast test reveals those people with folate (folic acid) or vitamin B12 deficiency, while the methionine test detects people who lack vitamin B6. Also, the researchers streamlined the second test so homocysteine can be measured two hours after a dose of methionine instead of four or six hours.
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts, Boston, MA
Andrew G. Bostom/Jacob Selhub, (617) 556-3356/-3191
People don't need to become severely deficient in magnesium for the brain to become hyperactive. A new study confirms earlier reports that a marginal magnesium intake overexcites the brain's neurons and results in less coherencecreating cacophony rather than symphonyaccording to electroencephalogram (EEG) measurements. Thirteen women consumed 115 milligrams of magnesium per day (mg/d)or about 40 percent of the Recommended Dietary Allowancefor half of the six-month study. During the other half, they got 315 mg/da little more than the 280 mg/d recommended intake for women. After only six weeks on the marginal intake, EEG readings showed significant differences in brain function. Magnesium is the fourth most abundant element in the brain and is essential in regulating central nervous system excitability. Clinical studies of people severely deficient in this essential element have reported epilepsy-type convulsions, dizziness and muscle tremors or twitching, as well as many psychological symptoms, including irritability, anxiety, confusion, depression, apathy, loss of appetite and insomnia. While the marginal intake in this study did not produce such severe symptoms, it did hype brain activity. This is the first experimental study in which magnesium intakes were tightly controlled and EEG measurements were analyzed by computer so that they could be statistically compared. Good sources of magnesium include whole grains, nuts, peanut butter, cottonseed, peanut and soybean flours, green leafy vegetables and spices.
Grand Forks Human Nutrition Research Center, Grand Forks, ND
James G. Penland, (701) 795-8471
Last updated: October 29, 1996
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Last Modified: 02/11/2002
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