A variety of fruits
and vegetables can be incorporated into a low-glycemic-load diet. Click the
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New Findings on Low-Glycemic-Load Diets for Weight
Loss By Rosalie
Marion Bliss December 27, 2005
A low-glycemic-load diet enhanced weight loss among certain volunteers
on a reduced-calorie diet for six months. The significant level of weight loss
was limited to those among the study participants who were considered
"high-insulin-secreting." The findings could lead to more customized
weight-loss strategies in the future, though the results must be replicated in
a larger study before being considered definitive.
The study findings were published in the December 2005 issue of Diabetes Care.
Greenberg were funded by the Agricultural Research Service (ARS). Roberts is director of the Energy
Metabolism Laboratory, and Greenberg is director of the Obesity and Metabolism
Laboratory, both at the Jean Mayer USDA Human Nutrition Research Center on
at Tufts University. Lead author
Anastassios G. Pittas is with the Tufts-New
England Medical Center. Both centers are based in Boston, Mass.
Roberts, Greenberg and Pittas worked with coauthors at both centers.
The study was performed at the HNRCA as part of a trial funded by the
National Institutes of Health.
The volunteers were all healthy but overweight adults--aged 24 to 42
years. Each was given a diet that provided 30 percent fewer calories than his
or her baseline calorie needs. Half the participants were randomly assigned to
a low-glycemic-load diet of 40 percent carbohydrates, 30 percent protein and 30
percent fat. The other half consumed a high-glycemic-load diet: 60 percent
carbohydrates, 20 percent protein and 20 percent fat.
All participants lost some weight as a result of restricting calories,
but those who lost the most had high baseline levels of insulin secretion and
ate the low-glycemic-load diet.
Glycemic load is a relative measure of how much carbohydrate is in the
diet combined with how quickly that food is converted in the body to blood
sugar. The volunteers' insulin secretion levels were based on their responses
to a standard, two-hour oral glucose tolerance test.
Further studies are planned for larger groups of volunteers.
ARS is the U.S. Department of
Agriculture's chief scientific research agency.