Page Banner

United States Department of Agriculture

Agricultural Research Service

Scientists Study Early Warning Stress Indicator in Animals / January 15, 2002 / News from the USDA Agricultural Research Service

Agricultural Research Service
U.S. Department of Agriculture
ARS News and Information Search News and Info Science for Kids Image Gallery Agricultural Research Magazine Publications and Newsletters News Archive News and Info home ARS News and Information
Latest news | Subscribe

Photo: Ted Elsasser prepares an injection of vitamin E to test its ability to relieve some effects of bacterial toxins. Link to photo information
Click image for caption and other photo information.

Read the magazine story to find out more.

Scientists Study Early Warning Stress Indicator in Animals

By Sharon Durham
January 15, 2002

Although an animal's life processes--such as giving birth and weaning--are natural, they can be stressful, and that stress can impair the animal’s normal biological functions. But how do you know how stressed an animal is? Agricultural Research Service scientist Ted H. Elsasser is close to answering that question.

Elsasser, based at the ARS Growth Biology Laboratory in Beltsville, Md., is investigating nitrated protein measurement as a biomarker of stress. Nitrated proteins, naturally present in the body, may serve as an early warning system for identifying an animal that may need help recovering from an illness, or that could yield unsafe meat or milk.

In response to high levels of infectious stress or injury, or when immune system hormones are secreted inside the animal, certain protein components, called tyrosines, can alter the function--and the shape--of the proteins. When this happens, the protein is said to be “nitrated.” Proteins are like jigsaw puzzle pieces that are designed to fit together to perform a specific function. When proteins are altered, they no longer fit and become ineffective.

Stress causes several undesirable effects, including slow animal growth and lowered immune response. Currently, farmers often use antibiotics to avert these effects. But sustained doses of antibiotics can accelerate the development of antibiotic-resistant bacteria that may later infect humans.

To slow the formation of nitrated--and thus ineffective--proteins, Elsasser is investigating vitamin E, a standard antioxidant supplement. Using vitamin E as a preconditioner allowed researchers to maintain animal growth rates better under stress and perhaps prevent the occurrence of secondary infections. Being able to prevent infections due to stress could lead to lower disease-management costs, less antibiotic use, and healthier animals.

A more detailed story appears in the January issue of Agricultural Research magazine.

ARS is the chief scientific research agency of the U.S. Department of Agriculture.

Top | News Staff | Photo Staff

E-mail the web team Privacy and other policies Site map About ARS Information Staff Bottom menu

Home | News | Pubs | Magazine | Photos | Sci4Kids | Search
About ARS Info | Site map | Policies | E-mail us

Last Modified: 1/15/2002
Footer Content Back to Top of Page