Table 1. Number of E.coli Isolates Tested from Chickens, 2000-2007
|
|
2000 |
2001 |
2002 |
2003 |
2004 |
2005 |
2006 |
2007 |
| Chickens |
285 |
1989 |
2100 |
1365 |
1697 |
2232 |
1357 |
1510 |
Table 2. Distribution of MICs and Occurrence of Resistance among E.coli Isolates from Chickens, 2007
|
| %I |
%R |
95% CI |
0.015 |
0.03 |
0.06 |
0.125 |
0.25 |
0.5 |
1 |
2 |
4 |
8 |
16 |
32 |
64 |
128 |
256 |
512 |
1024 |
| Amikacin |
0 |
0 |
0.0-0.3 |
|
|
|
|
|
1.7 |
32.3 |
54.8 |
10.1 |
1.1 |
|
|
|
|
|
|
|
| Gentamicin |
6.7 |
38 |
35.6-40.5 |
|
|
|
|
9 |
37.5 |
5.8 |
1.1 |
1.9 |
6.7 |
16.9 |
21.1 |
|
|
|
|
|
| Kanamycin |
1.7 |
7.7 |
6.4-9.2 |
|
|
|
|
|
|
|
|
|
81.9 |
8.7 |
1.7 |
0.6 |
7.2 |
|
|
|
| Streptomycin |
N/A |
47 |
44.5-49.6 |
|
|
|
|
|
|
|
|
|
|
|
53 |
24.2 |
22.8 |
|
|
|
| Ampicillin |
0.1 |
18.7 |
16.8-20.8 |
|
|
|
|
|
|
20.1 |
43 |
17.9 |
0.3 |
0.1 |
0.8 |
17.9 |
|
|
|
|
| Amoxicillin-Clavulanic Acid |
0.5 |
11.2 |
9.7-12.9 |
|
|
|
|
|
|
6 |
38.1 |
35.8 |
8.5 |
0.5 |
9.2 |
2 |
|
|
|
|
| Ceftiofur |
2.6 |
7 |
5.8-8.4 |
|
|
|
8.5 |
49.1 |
30 |
1.7 |
1 |
2.6 |
5.4 |
1.6 |
|
|
|
|
|
|
| Ceftriaxone |
2.6 |
0.1 |
0-0.5 |
|
|
|
|
88.1 |
0.5 |
0.7 |
0.3 |
2.1 |
5.6 |
2.5 |
0.1 |
0 |
0.1 |
|
|
|
| Cefoxitin |
1.9 |
10.3 |
8.8-12.0 |
|
|
|
|
|
0.1 |
2.4 |
25.1 |
46.9 |
13.4 |
1.9 |
6.5 |
3.8 |
|
|
|
|
| Sulfonamides |
N/A |
53.2 |
50.6-55.7 |
|
|
|
|
|
|
|
|
|
|
42 |
4 |
0.1 |
0.2 |
0.4 |
53.2 |
|
| Trimethoprim-Sulfamethoxazole |
N/A |
7.9 |
6.6-9.4 |
|
|
|
63.7 |
17.4 |
5.9 |
4 |
1.1 |
0.1 |
7.9 |
|
|
|
|
|
|
|
| Chloramphenicol |
0.6 |
2.3 |
1.6-3.2 |
|
|
|
|
|
|
|
14.6 |
61.5 |
21 |
0.6 |
0.2 |
2.1 |
|
|
|
|
| Ciprofloxacin |
0 |
0.1 |
0-0.5 |
90.6 |
5.1 |
0.2 |
2.1 |
1.7 |
0.3 |
0 |
0 |
0 |
0.1 |
|
|
|
|
|
|
|
| Nalidixic Acid |
N/A |
4.2 |
3.3-5.4 |
|
|
|
|
|
2.5 |
26 |
55.4 |
11.5 |
0.3 |
0.1 |
0.9 |
3.3 |
|
|
|
|
| Tetracycline |
1.8 |
40.2 |
37.7-42.7 |
|
|
|
|
|
|
|
|
58 |
1.8 |
6 |
17.2 |
17 |
|
|
|
|
Table 3. Percent Antimicrobial Resistance among E.coli Isolates from Chickens by Year, 2000-2007
|
|
2000 |
Table 2 notes:
95% confidence intervals for percent resistant (%R) were calculated using the Clopper-Pearson exact method
Antimicrobial subclasses and susceptible, intermediate and resistance breakpoints can be found in the antimicrobials and breakpoints section.
N/A- Not applicable
2001 |
2002 |
2003 |
2004 |
2005 |
2006 |
2007 |
| Amikacin |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
| Gentamicin |
40 |
33.4 |
38 |
38.8 |
39.1 |
36.7 |
33.1 |
38 |
| Kanamycin |
16.1 |
14.5 |
11.6 |
10.3 |
11.5 |
10.3 |
9.1 |
7.7 |
| Streptomycin |
77.5 |
65.8 |
65.1 |
64.2 |
64.1 |
58 |
49.5 |
47 |
| Ampicillin |
20 |
19.5 |
19 |
18.6 |
17.6 |
22 |
25.6 |
18.7 |
| Amoxicillin-Clavulanic Acid |
8.1 |
10 |
10.9 |
11.1 |
8.8 |
10.6 |
16 |
11.2 |
| Ceftiofur |
6.3 |
4.4 |
5.5 |
7.1 |
4.9 |
6.5 |
10.2 |
7 |
| Ceftriaxone |
0 |
0 |
0 |
0 |
0.1 |
0 |
0.1 |
0.1 |
| Cephalothin |
17.9 |
12.9 |
15.1 |
16.6 |
NT |
NT |
NT |
NT |
| Cefoxitin |
7.4 |
8.7 |
8.5 |
8.3 |
8.2 |
9.9 |
15 |
10.3 |
| Sulfonamides |
57.9 |
58.2 |
46.1 |
43.9 |
53.2 |
51.9 |
48.6 |
53.2 |
| Trimethoprim- |
17.2 |
12.6 |
10.4 |
10.5 |
10.7 |
10.4 |
8.4 |
7.9 |
| Chloramphenicol |
4.6 |
2.4 |
1.8 |
1.3 |
1 |
1 |
1.9 |
2.3 |
| Ciprofloxacin |
0 |
0.2 |
0 |
0.1 |
0.2 |
0.4 |
0 |
0.1 |
| Nalidixic Acid |
10.2 |
8.4 |
6.8 |
6.2 |
6.8 |
7.5 |
5.4 |
4.2 |
| Tetracycline |
68.4 |
61.6 |
58.6 |
52.2 |
50.3 |
48.9 |
1.3 |
40.2 |
Table 3 notes:
NT: Not tested
Table 4. Percent Frequency of Resistance Patterns of E.coli Isolates, by Year, 2000-2007
|
|
2000 |
2001 |
2002 |
2003 |
2004 |
2005 |
2006 |
2007 |
| No Resistance detected |
10.2 |
12.9 |
15.9 |
16 |
17 |
17.7 |
18.6 |
24.4 |
| Resistance >1 CLSI subclass |
89.8 |
87.1 |
84.1 |
84 |
83 |
82.3 |
81.4 |
75.6 |
| Resistance >2 CLSI subclasses |
76.8 |
21.7 |
68 |
65 |
66.5 |
64.7 |
62.9 |
60.8 |
| Resistance >3 CLSI subclasses |
55.1 |
34.2 |
43.3 |
38.9 |
42.3 |
41.1 |
42.9 |
36.1 |
| Resistance >4 CLSI subclasses |
18.9 |
7.9 |
13.8 |
13 |
11.5 |
14.7 |
16.6 |
12.6 |
| Resistance >5 CLSI subclasses |
7.7 |
4.1 |
6.6 |
6.4 |
4.8 |
6.8 |
7.3 |
6 |
Table 4 notes:
CLSI: Clinical and Laboratory Standards Institute M100 Document